公开(公告)号：US10711043B2

公开(公告)日：2020-07-14

申请号：US16030506

申请日：2018-07-09

申请人： University of Maryland, College Park ,  University of Maryland, Baltimore

发明人： Philip R. DeShong ,  Lenea Stocker ,  Daniel C. Stein ,  Stefanie N. Vogel ,  Katharina Richard

IPC分类号： A61K39/095 ,  A61K39/02 ,  A61K49/00 ,  C07K14/195 ,  C07K14/22 ,  A61K39/39 ,  A61K39/00

摘要： The disclosure relates to compositions, pharmaceutical compositions, vaccines, and methods of making and using the same. The compositions of the disclosure are useful to stimulate an antigen-specific immune response and, in some embodiments, a protective immune response in an animal after challenge to pathogens. The compositions of the disclosure are also useful for treatment and prevention of disease in a subject such as cancer.

公开(公告)号：US20190016761A1

公开(公告)日：2019-01-17

申请号：US16030506

申请日：2018-07-09

申请人： University of Maryland, College Park ,  University of Maryland, Baltimore

发明人： Philip R. DeShong ,  Lenea Stocker ,  Daniel C. Stein ,  Stefanie N. Vogel ,  Katharina Richard

IPC分类号： C07K14/195 ,  A61K39/39 ,  A61K39/095

CPC分类号： C07K14/195 ,  A61K39/0208 ,  A61K39/095 ,  A61K39/39 ,  A61K2039/55555 ,  C07K14/22

摘要： The disclosure relates to compositions, pharmaceutical compositions, vaccines, and methods of making and using the same. The compositions of the disclosure are useful to stimulate an antigen-specific immune response and, in some embodiments, a protective immune response in an animal after challenge to pathogens. The compositions of the disclosure are also useful for treatment and prevention of disease in a subject such as cancer.

公开(公告)号：US10017545B2

公开(公告)日：2018-07-10

申请号：US14295306

申请日：2014-06-03

申请人： University of Maryland, College Park ,  University of Maryland, Baltimore

发明人： Philip R. DeShong ,  Lenea Stocker ,  Daniel C. Stein ,  Stefanie N. Vogel ,  Katharina Richard

IPC分类号： A61K49/00 ,  A61K39/00 ,  A61K39/02 ,  C07K14/195 ,  A61K39/095 ,  C07K14/22 ,  A61K39/39

CPC分类号： C07K14/195 ,  A61K39/0208 ,  A61K39/095 ,  A61K39/39 ,  A61K2039/55555 ,  C07K14/22

摘要： The disclosure relates to compositions, pharmaceutical compositions, vaccines, and methods of making and using the same. The compositions of the disclosure are useful to stimulate an antigen-specific immune response and, in some embodiments, a protective immune response in an animal after challenge to pathogens. The compositions of the disclosure are also useful for treatment and prevention of disease in a subject such as cancer.

公开(公告)号：US20140356415A1

公开(公告)日：2014-12-04

申请号：US14295306

申请日：2014-06-03

申请人： University of Maryland, College Park ,  University of Maryland, Baltimore

发明人： Philip R. DeShong ,  Lenea Stocker ,  Daniel C. Stein ,  Stefanie N. Vogel ,  Katharina Richard

IPC分类号： A61K9/127 ,  C07K14/195 ,  C07K14/22 ,  A61K39/095 ,  A61K39/02

CPC分类号： C07K14/195 ,  A61K39/0208 ,  A61K39/095 ,  A61K39/39 ,  A61K2039/55555 ,  C07K14/22

摘要： The disclosure relates to compositions, pharmaceutical compositions, vaccines, and methods of making and using the same. The compositions of the disclosure are useful to stimulate an antigen-specific immune response and, in some embodiments, a protective immune response in an animal after challenge to pathogens. The compositions of the disclosure are also useful for treatment and prevention of disease in a subject such as cancer.

摘要翻译： 本公开涉及组合物，药物组合物，疫苗及其制备和使用方法。 本公开的组合物可用于刺激抗原特异性免疫应答，并且在一些实施方案中，在攻击病原体后在动物中具有保护性免疫应答。 本公开的组合物还可用于治疗和预防患者如癌症中的疾病。