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公开(公告)号：US20170340432A1
公开(公告)日：2017-11-30
申请号：US15453115
申请日：2017-03-08
发明人： Mohammed S. El-Kurdi , J. Christopher Flaherty , Yi Hong , Jonathan McGrath , Lorenzo Soletti , John J. Stankus , David A. Vorp , William R. Wagner
CPC分类号： A61F2/06 , A61F2/04 , A61F2/062 , A61F2002/072
摘要： A tubular tissue graft device is provided comprising a tubular member and a restrictive fiber matrix of a bioerodible polymer about a circumference of the tubular tissue. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. Also provided is method of preparing a tubular graft comprising depositing a fiber matrix of a bioerodible polymer about a perimeter of a tubular tissue to produce a tubular tissue graft device. A cardiac bypass method comprising bypassing a coronary artery with a tubular tissue graft device comprising a vein and a restrictive fiber matrix of a bioerodible polymer about a circumference of the vein also is provided.
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公开(公告)号：US20160317280A1
公开(公告)日：2016-11-03
申请号：US15086612
申请日：2016-03-31
发明人： Mohammed S. El-Kurdi , Yi Hong , Lorenzo Soletti , John J. Stankus , David A. Vorp , William R. Wagner
CPC分类号： A61F2/06 , A61F2/07 , A61F2210/0004 , A61F2210/0076 , A61F2240/001 , A61F2250/0067 , A61L27/18 , A61L27/34 , A61L27/3625 , A61L27/3683 , A61L27/3691 , A61L27/3804 , A61L27/3826 , A61L27/507 , A61L27/54 , A61L27/58 , A61L2300/414 , A61L2300/604 , A61L2430/22 , C12N5/0068 , C12N2533/40 , D01D5/0007 , D01D5/0076 , D10B2331/10 , D10B2401/12 , D10B2509/06 , C08L67/04
摘要： A tubular tissue graft device is provided comprising a tubular tissue and a restrictive fiber matrix of a bioerodible polymer about a circumference of the tubular tissue. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. Also provided is method of preparing a tubular graft comprising depositing a fiber matrix of a bioerodible polymer about a perimeter of a tubular tissue to produce a tubular tissue graft device. A cardiac bypass method comprising bypassing a coronary artery with a tubular tissue graft device comprising a vein and a restrictive fiber matrix of a bioerodible polymer about a circumference of the vein also is provided.
摘要翻译： 提供了一种管状组织移植装置，其包括管状组织和围绕管状组织的圆周的生物可蚀解聚合物的限制性纤维基质。 基质可以电纺到管状组织上。 在一个实施例中，管状组织来自静脉，例如隐静脉，可用作动脉移植物，例如但不限于冠状动脉旁路手术。 还提供了制备管状移植物的方法，其包括围绕管状组织的周边沉积生物可蚀解聚合物的纤维基质以产生管状组织移植装置。 还提供了一种包括绕管冠状动脉的心脏旁路方法，所述管状组织移植装置包括静脉和围绕静脉周围的生物可蚀解聚合物的限制性纤维基质。
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公开(公告)号：US20240299155A1
公开(公告)日：2024-09-12
申请号：US18505610
申请日：2023-11-09
发明人： Mohammed S. El-Kurdi , William R. Wagner , David A. Vorp , John J. Stankus , Lorenzo Soletti , Jonathan McGrath , Yi Hong , J. Christopher Flaherty
CPC分类号： A61F2/06 , A61F2/04 , A61F2/062 , A61F2002/072
摘要： A tubular tissue graft device is provided comprising a tubular member and a restrictive fiber matrix of a bioerodible polymer about a circumference of the tubular tissue. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. Also provided is method of preparing a tubular graft comprising depositing a fiber matrix of a bioerodible polymer about a perimeter of a tubular tissue to produce a tubular tissue graft device. A cardiac bypass method comprising bypassing a coronary artery with a tubular tissue graft device comprising a vein and a restrictive fiber matrix of a bioerodible polymer about a circumference of the vein also is provided.
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公开(公告)号：US09333068B2
公开(公告)日：2016-05-10
申请号：US14601523
申请日：2015-01-21
发明人： Mohammed S. El-Kurdi , Yi Hong , Lorenzo Soletti , John J. Stankus , David A. Vorp , William R. Wagner
IPC分类号： A61F2/06 , D01D5/00 , A61L27/38 , A61L27/36 , A61L27/34 , A61L27/50 , A61L27/54 , A61L27/58 , C12N5/00
CPC分类号： A61F2/06 , A61F2/07 , A61F2210/0004 , A61F2210/0076 , A61F2240/001 , A61F2250/0067 , A61L27/18 , A61L27/34 , A61L27/3625 , A61L27/3683 , A61L27/3691 , A61L27/3804 , A61L27/3826 , A61L27/507 , A61L27/54 , A61L27/58 , A61L2300/414 , A61L2300/604 , A61L2430/22 , C12N5/0068 , C12N2533/40 , D01D5/0007 , D01D5/0076 , D10B2331/10 , D10B2401/12 , D10B2509/06 , C08L67/04
摘要： A tubular tissue graft device is provided comprising a tubular tissue and a restrictive fiber matrix of a bioerodible polymer about a circumference of the tubular tissue. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. Also provided is method of preparing a tubular graft comprising depositing a fiber matrix of a bioerodible polymer about a perimeter of a tubular tissue to produce a tubular tissue graft device. A cardiac bypass method comprising bypassing a coronary artery with a tubular tissue graft device comprising a vein and a restrictive fiber matrix of a bioerodible polymer about a circumference of the vein also is provided.
摘要翻译： 提供了一种管状组织移植装置，其包括管状组织和围绕管状组织的圆周的生物可蚀解聚合物的限制性纤维基质。 基质可以电纺到管状组织上。 在一个实施例中，管状组织来自静脉，例如隐静脉，可用作动脉移植物，例如但不限于冠状动脉旁路手术。 还提供了制备管状移植物的方法，其包括围绕管状组织的周边沉积生物可蚀解聚合物的纤维基质以产生管状组织移植装置。 还提供了一种包括绕管冠状动脉的心脏旁路方法，所述管状组织移植装置包括静脉和围绕静脉周围的生物可蚀解聚合物的限制性纤维基质。
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公开(公告)号：US20150150673A1
公开(公告)日：2015-06-04
申请号：US14601523
申请日：2015-01-21
发明人： Mohammed S. El-Kurdi , Yi Hong , Lorenzo Soletti , John J. Stankus , David A. Vorp , William R. Wagner
CPC分类号： A61F2/06 , A61F2/07 , A61F2210/0004 , A61F2210/0076 , A61F2240/001 , A61F2250/0067 , A61L27/18 , A61L27/34 , A61L27/3625 , A61L27/3683 , A61L27/3691 , A61L27/3804 , A61L27/3826 , A61L27/507 , A61L27/54 , A61L27/58 , A61L2300/414 , A61L2300/604 , A61L2430/22 , C12N5/0068 , C12N2533/40 , D01D5/0007 , D01D5/0076 , D10B2331/10 , D10B2401/12 , D10B2509/06 , C08L67/04
摘要： A tubular tissue graft device is provided comprising a tubular tissue and a restrictive fiber matrix of a bioerodible polymer about a circumference of the tubular tissue. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. Also provided is method of preparing a tubular graft comprising depositing a fiber matrix of a bioerodible polymer about a perimeter of a tubular tissue to produce a tubular tissue graft device. A cardiac bypass method comprising bypassing a coronary artery with a tubular tissue graft device comprising a vein and a restrictive fiber matrix of a bioerodible polymer about a circumference of the vein also is provided.
摘要翻译： 提供了一种管状组织移植装置，其包括管状组织和围绕管状组织的圆周的生物可蚀解聚合物的限制性纤维基质。 基质可以电纺到管状组织上。 在一个实施例中，管状组织来自静脉，例如隐静脉，可用作动脉移植物，例如但不限于冠状动脉旁路手术。 还提供了制备管状移植物的方法，其包括围绕管状组织的周边沉积生物可蚀解聚合物的纤维基质以产生管状组织移植装置。 还提供了一种包括绕管冠状动脉的心脏旁路方法，所述管状组织移植装置包括静脉和围绕静脉周围的生物可蚀解聚合物的限制性纤维基质。
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公开(公告)号：US11850141B2
公开(公告)日：2023-12-26
申请号：US16577579
申请日：2019-09-20
发明人： Mohammed S. El-Kurdi , William R. Wagner , David A. Vorp , John J. Stankus , Lorenzo Soletti , Jonathan McGrath , Yi Hong , J Christopher Flaherty
CPC分类号： A61F2/06 , A61F2/04 , A61F2/062 , A61F2002/072
摘要： A tubular tissue graft device is provided comprising a tubular member and a restrictive fiber matrix of a bioerodible polymer about a circumference of the tubular tissue. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. Also provided is method of preparing a tubular graft comprising depositing a fiber matrix of a bioerodible polymer about a perimeter of a tubular tissue to produce a tubular tissue graft device. A cardiac bypass method comprising bypassing a coronary artery with a tubular tissue graft device comprising a vein and a restrictive fiber matrix of a bioerodible polymer about a circumference of the vein also is provided.
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公开(公告)号：US20200237494A1
公开(公告)日：2020-07-30
申请号：US16577579
申请日：2019-09-20
发明人： Mohammed S. El-Kurdi , William R. Wagner , David A. Vorp , John J. Stankus , Lorenzo Soletti , Jonathan McGrath , Yi Hong , J. Christopher Flaherty
IPC分类号： A61F2/06
摘要： A tubular tissue graft device is provided comprising a tubular member and a restrictive fiber matrix of a bioerodible polymer about a circumference of the tubular tissue. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. Also provided is method of preparing a tubular graft comprising depositing a fiber matrix of a bioerodible polymer about a perimeter of a tubular tissue to produce a tubular tissue graft device. A cardiac bypass method comprising bypassing a coronary artery with a tubular tissue graft device comprising a vein and a restrictive fiber matrix of a bioerodible polymer about a circumference of the vein also is provided.
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