公开(公告)号：US09750814B2

公开(公告)日：2017-09-05

申请号：US15262716

申请日：2016-09-12

Applicant: University of Washington

Inventor： Erik Procko ,  David Baker ,  Geoffrey Y. Berguig ,  Patrick S. Stayton ,  Yifan Song ,  Stephanie Ann Berger ,  Daniel-Adriano Silva

IPC: A61K47/32 ,  C07K14/47 ,  A61K38/17 ,  A61K39/395 ,  C07K14/00 ,  G01N33/569 ,  C07K16/08 ,  C07K14/005 ,  C12N5/0781 ,  A61K39/12

CPC classification number: A61K47/32 ,  A61K38/1709 ,  A61K39/395 ,  A61K47/645 ,  C07K14/4747 ,  C07K16/085 ,  C07K14/005 ,  C07K2317/76 ,  C12N5/0635 ,  C12N2710/16211 ,  C12N5/0636 ,  C12N2710/16234 ,  C12N7/00 ,  A61K39/245 ,  A61K39/12 ,  A61K35/17 ,  C07K2317/34 ,  C07K14/001 ,  G01N33/56994 ,  G01N2333/05 ,  C07K14/4748

Abstract: The present invention provides designed polypeptides that selectively bind to and inhibit Epstein Barr protein BHFR1, and B cell lymphoma family proteins, and are thus useful for treating Epstein Barr-related diseases and cancer.