专利检索 ap:("VSY BIYOTEKNOLOJI VE ILAC SANAYI ANONIM SIRKETI") AND inv:"Mustafa CIFTCI" 第 1 页

1.

发明公开
INJECTABLE PHOTOCROSSLINKED HYALURONIC ACID HYDROGELS, PRODUCTION METHOD THEREOF AND THEIR USE FOR THE TREATMENT OF OSTEOARTHRITIS 审中-公开

公开(公告)号：US20240050628A1

公开(公告)日：2024-02-15

申请号：US18269760

申请日：2021-12-28

申请人： VSY BIYOTEKNOLOJI VE ILAC SANAYI ANONIM SIRKETI

发明人： Faruk OYTUN , Mustafa CIFTCI , Busra Gizem KAYA

IPC分类号： A61L27/52 , C08B37/08 , C08J3/075 , C08L5/08 , A61L27/20

CPC分类号： A61L27/52 , C08B37/0072 , C08J3/075 , C08L5/08 , A61L27/20 , C08J2305/08 , A61L2430/06 , A61L2400/06

摘要： An injectable viscoelastic hydrogel formulation comprising photocrosslinked hyaluronic acid in order to relieve pain caused by osteoarthritis (OA), to support synovial fluid which has decreased activity, and to treat osteochondral lesions is provided. In the production of hyaluronic acid (HA) hydrogels, the crosslinking process is carried out via biocompatible camphorquinone instead of synthetic crosslinkers having toxic effects. Therefore, long process times in the purification process of synthetic crosslinkers are significantly reduced with the present invention.