公开(公告)号：USRE42835E1

公开(公告)日：2011-10-11

申请号：US12571974

申请日：2009-10-01

申请人： Victor Chornenky ,  Ali Jaafar

发明人： Victor Chornenky ,  Ali Jaafar

IPC分类号： A61N1/18

CPC分类号： A61N1/327 ,  A61N1/0412 ,  A61N1/0424 ,  A61N1/0456 ,  A61N1/328 ,  A61N1/36021

摘要： An apparatus and method for non-invasive treatment in lieu of cosmetic surgery is disclosed. The apparatus comprises a combination of a high and low voltage pulse generators connected to two or more electrodes placed on a treatment site of the patient's body. High voltage pulses, delivered to the electrodes, create an electric field that kills subcutaneous fat cells. Low voltage pulses, delivered to the same or individual electrodes provide transcutaneous electrical nerve stimulation (TENS), blocking the signals of discomfort or pain that may arise from the high voltage pulsing.

摘要翻译： 公开了一种用于非侵入性治疗代替整容手术的装置和方法。 该装置包括连接到放置在患者身体的治疗部位上的两个或多个电极的高电压脉冲发生器和低压脉冲发生器的组合。 输送到电极的高电压脉冲产生杀死皮下脂肪细胞的电场。 传递到相同或单独电极的低电压脉冲提供经皮电神经刺激（TENS），阻止由高压脉冲引起的不适或疼痛的信号。

公开(公告)号：US06994706B2

公开(公告)日：2006-02-07

申请号：US10217749

申请日：2002-08-13

申请人： Victor Chornenky ,  Ali Jaafar

发明人： Victor Chornenky ,  Ali Jaafar

IPC分类号： A61B18/18

CPC分类号： A61B18/1492 ,  A61B18/12 ,  A61B18/1206 ,  A61B2018/00029 ,  A61B2018/00285 ,  A61B2018/00434 ,  A61B2018/00517 ,  A61B2018/00547 ,  A61B2018/00613 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/124 ,  A61N1/325

摘要： An apparatus and a method for treatment of benign prostatic hyperplasia are disclosed. The apparatus includes an applicator piece carrying a set of electrodes shaped and positioned to create a substantial electric field in the volume of hyperplasia and a pulse generator adapted for delivery of electrical pulses above the upper electroporation limit for the neoplastic cells. The amplitude, duration and number of the electrical pulses are generally selected to cause necrosis of a significant fraction of the volume of benign prostatic hyperplasia. The apparatus may include a high frequency system for heating the prostatic tissue and a cooling system for cooling the urethra. The combined action of heating and cooling may increase the temperature of the prostate cells to 45° C. to 55° C., while keeping the urinary tract at a temperature 15° C. to 20° C. This temperature distribution can increase the selectivity of the treatment by increasing susceptibility of the neoplastic cells to the electroporation treatment and decreasing it for the normal urethral tissues.

公开(公告)号：US20060079860A1

公开(公告)日：2006-04-13

申请号：US11285123

申请日：2005-11-22

申请人： Victor Chornenky ,  Ali Jaafar

发明人： Victor Chornenky ,  Ali Jaafar

IPC分类号： A61M31/00

CPC分类号： A61M5/1456 ,  A61J3/002 ,  A61M5/1407 ,  A61M5/14244 ,  A61M5/1452 ,  A61M5/172 ,  A61M5/44 ,  A61M39/223 ,  A61M2005/1402 ,  A61M2205/3553 ,  A61M2205/3584 ,  A61M2205/3606 ,  A61M2205/50 ,  A61M2205/8206

摘要： This invention provides an apparatus and method for emergency administration or self-administration of thrombolytic therapy in early stage of a heart attack. The apparatus includes a needle injector for making a venipuncture, a battery operated micro cooler for maintaining low temperature environment for vials with lyophilized thrombolytic and adjuvant drugs, a container with a diluent for reconstitution of the lyophilized drugs, a programmable infusion pump, and a microprocessor for controlling the process of infusion and recording the data. As the system is activated, said container becomes fluidly communicable with the infusion pump and vials with drugs in the cooler. Designed for autonomous execution of several schedules of infusion, it also can be controlled remotely by a qualified operator via an Internet interface.

公开(公告)号：US20060020170A1

公开(公告)日：2006-01-26

申请号：US11222573

申请日：2005-09-09

申请人： Victor Chornenky ,  Ali Jaafar

发明人： Victor Chornenky ,  Ali Jaafar

IPC分类号： A61B1/00

CPC分类号： A61N5/1001 ,  A61B1/32 ,  H01J35/065 ,  H01J35/32 ,  H01J2235/064 ,  H01J2235/164

摘要： An appliance for use in delivering x-ray radiation therapy internally at desired locations in a body is disclosed. The appliance may be inserted into the tissue to receive radiation and expanded to a desired shape, thereby providing a predetermined configuration to the tissue surrounding the appliance. The appliance can be configured to provide a spherical shape, for example, or an elliptical shape if desired.

摘要翻译： 公开了一种用于在体内所需位置内部输送x射线放射治疗的器具。 器具可以插入到组织中以接收辐射并且膨胀到期望的形状，从而为器具周围的组织提供预定的构造。 如果需要，器具可以被配置为提供球形形状，例如椭圆形。

公开(公告)号：US20060217703A1

公开(公告)日：2006-09-28

申请号：US11347965

申请日：2006-02-06

申请人： Victor Chornenky ,  Ali Jaafar

发明人： Victor Chornenky ,  Ali Jaafar

IPC分类号： A61B18/14

CPC分类号： A61B18/1492 ,  A61B18/12 ,  A61B18/1206 ,  A61B2018/00029 ,  A61B2018/00285 ,  A61B2018/00434 ,  A61B2018/00517 ,  A61B2018/00547 ,  A61B2018/00613 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/124 ,  A61N1/325

摘要： An apparatus and a method for treatment of benign prostatic hyperplasia are disclosed. The apparatus includes an applicator piece carrying a set of electrodes shaped and positioned to create a substantial electric field in the volume of hyperplasia and a pulse generator adapted for delivery of electrical pulses above the upper electroporation limit for the neoplastic cells. The amplitude, duration and number of the electrical pulses are generally selected to cause necrosis of a significant fraction of the volume of benign prostatic hyperplasia. The apparatus may include a high frequency system for heating the prostatic tissue and a cooling system for cooling the urethra. The combined action of heating and cooling may increase the temperature of the prostate cells to 45 degrees C. to 55 degrees C., while keeping the urinary tract at a temperature 15 degrees C. to 20 degrees C. This temperature distribution can increase the selectivity of the treatment by increasing susceptibility of the neoplastic cells to the electroporation treatment and decreasing it for the normal urethral tissues.

摘要翻译： 公开了一种用于治疗良性前列腺增生的装置和方法。 该装置包括一个施加器部件，其承载一组电极，其形状和位置以在增生体积中产生实质电场，以及脉冲发生器适用于递送高于肿瘤细胞上电穿孔极限的电脉冲。 通常选择电脉冲的幅度，持续时间和数量以使良性前列腺增生体积的显着部分坏死。 该装置可以包括用于加热前列腺组织的高频系统和用于冷却尿道的冷却系统。 加热和冷却的联合作用可将前列腺细胞的温度升高至45摄氏度至55摄氏度，同时将尿道保持在15摄氏度至20摄氏度的温度。该温度分布可提高选择性 通过增加肿瘤细胞对电穿孔治疗的敏感性并将其降低为正常的尿道组织来治疗。

公开(公告)号：US20060067467A1

公开(公告)日：2006-03-30

申请号：US11236147

申请日：2005-09-27

申请人： Victor Chornenky ,  Ali Jaafar

发明人： Victor Chornenky ,  Ali Jaafar

IPC分类号： A61N5/10

CPC分类号： A61N5/1015

摘要： A system and method providing conformal x-ray brachytherapy for treatment of a body having a tumor by irradiation of a target volume of tissue in a patient is disclosed wherein an x-ray probe including an x-ray emitter, an imaging probe configured to image the target volume, a translation stage mounting the x-ray probe for translational motion, a rotation stage mounting the x-ray probe for rotational motion, a compliant balloon inserted into a cavity created in a body by excision of a tumor, and computer operatively connected to the x-ray and imaging probes and the rotation and translation stages are provided to image and control the operation of the x-ray probe to irradiate the target volume according to predetermined treatment protocols.

摘要翻译： 公开了一种提供适形X射线近距离放射疗法的系统和方法，用于通过照射患者的目标体积的组织来治疗患有肿瘤的身体，其中包括x射线发射器的X射线探针，被配置为成像的成像探针 目标体积，安装用于平移运动的x射线探针的平移台，安装用于旋转运动的x射线探针的旋转台，插入通过切除肿瘤而在体内产生的腔中的顺应性球囊，以及可操作地计算机 连接到x射线和成像探针，并且提供旋转和平移阶段以根据预定的治疗方案对X射线探针的操作进行成像和控制以照射目标体积。

公开(公告)号：US20060074303A1

公开(公告)日：2006-04-06

申请号：US11236065

申请日：2005-09-27

申请人： Victor Chornenky ,  Ali Jaafar

发明人： Victor Chornenky ,  Ali Jaafar

IPC分类号： A61B5/05 ,  A61N5/00

CPC分类号： A61N5/1027 ,  A61B8/12

摘要： A system and method providing conformal x-ray brachytherapy for treatment of tumors by irradiation of a target volume of tissue in a patient is disclosed wherein an x-ray probe including an x-ray emitter, an imaging probe configured to image the target volume, a translation stage mounting the x-ray probe for translational motion, a rotation stage mounting the x-ray probe for rotational motion, a support base mounting the x-ray and imaging probes in known relation to each other, and a computer operatively connected to the x-ray and imaging probes and the rotation and translation stages are provided to image and control the operation of the x-ray probe to irradiate the target volume according to predetermined treatment protocols.

摘要翻译： 公开了一种提供适形X射线近距离放射疗法用于通过照射患者中的组织的靶体积来治疗肿瘤的系统和方法，其中包括x射线发射器的X射线探针，被配置成对目标体积进行成像的成像探针， 安装用于平移运动的x射线探针的平移台，安装用于旋转运动的x射线探针的旋转台，将X射线和成像探针以已知关系彼此安装的支撑基座，以及可操作地连接到 提供x射线和成像探针以及旋转和平移阶段以根据预定的治疗方案对X射线探针的操作进行成像和控制以照射目标体积。

公开(公告)号：US20050182462A1

公开(公告)日：2005-08-18

申请号：US11106835

申请日：2005-04-15

申请人： Victor Chornenky ,  Ali Jaafar

发明人： Victor Chornenky ,  Ali Jaafar

IPC分类号： A61N1/32 ,  A61N1/34 ,  A61F7/00 ,  A61F2/00 ,  A61F7/12

CPC分类号： A61N1/325 ,  A61N1/0424 ,  A61N1/327 ,  A61N1/328 ,  A61N1/36014

摘要： An apparatus and method for performing non-invasive treatment of the human face and body by electroporation in lieu of cosmetic surgery is provided. The apparatus comprises a high voltage pulse generator and an applicator having two or more electrodes in close mechanical and electrical contact with the patient's skin for applying the pulses to the patient's skin. The applicator may consist of two pieces with one electrode having a sharp tip and another having a flat surface. High voltage pulses delivered to the electrodes create at the tip of the sharp electrode an electric field high enough to cause death of relatively large subcutaneous fat cells by electroporation. Moving the electrode tip along the skin creates a line of necrotic subcutaneous fat cells, which later are metabolized by the body. Multiple applications of the electrode along predetermined lines on the face or neck create shrinkage of the skin and the subcutaneous fat volume underlying the treated area.

公开(公告)号：US20050038488A1

公开(公告)日：2005-02-17

申请号：US10938971

申请日：2004-09-10

申请人： Ali Jaafar ,  Victor Chornenky

发明人： Ali Jaafar ,  Victor Chornenky

IPC分类号： A61N5/10 ,  H01J35/06 ,  H01J35/32 ,  A61F2/00

CPC分类号： A61N5/1001 ,  A61B1/32 ,  A61N5/1014 ,  H01J35/065 ,  H01J35/32 ,  H01J2235/064 ,  H01J2235/164

摘要： The present invention provides apparatus and method for providing a stabilized x-ray output from a field emission x-ray apparatus by monitoring the operating current and adjusting the gap between the anode and cathode to stabilize the output.

摘要翻译： 本发明提供了一种用于通过监测工作电流并调节阳极和阴极之间的间隙来提供来自场发射x射线装置的稳定的x射线输出以稳定输出的装置和方法。

公开(公告)号：US20070161982A1

公开(公告)日：2007-07-12

申请号：US11690175

申请日：2007-03-23

申请人： Victor Chornenky ,  Ali Jaafar

发明人： Victor Chornenky ,  Ali Jaafar

IPC分类号： A61B18/18

CPC分类号： A61N1/0424 ,  A61B18/14 ,  A61B2018/00476 ,  A61N1/325

摘要： The present invention provides method for removal of body hair using electroporation using an apparatus having a pulse generator capable of generating electrical pulses of the desired amplitude and duration to kill hair follicles and an applicator having a first electrode placed in contact with a hair follicle and a second electrode interacting with the first electrode to provide an electroporating field in the tissue volume surrounding a hair to be removed. The method utilize a TENS system to provide patient relief from discomfort experienced by application of the electroporation pulses.

摘要翻译： 本发明提供了使用具有脉冲发生器的装置的电穿孔去除身毛的方法，所述脉冲发生器能够产生所需振幅和持续时间的电脉冲以杀死毛囊，以及具有放置成与毛囊接触的第一电极的施用器和 第二电极与第一电极相互作用，以在围绕要去除的毛发的组织体积中提供电穿孔区域。 该方法利用TENS系统来提供患者缓解通过施加电穿孔脉冲所经历的不适。