公开(公告)号：US20150165233A1

公开(公告)日：2015-06-18

申请号：US14617652

申请日：2015-02-09

Applicant: ViewRay Incorporated

Inventor： James F. Dempsey ,  Iwan Kawrykow

IPC: A61N5/10

CPC classification number: A61N5/1031 ,  A61N5/1036 ,  A61N5/1045 ,  A61N5/1071 ,  A61N5/1077

Abstract: The subject matter described herein provides methods for developing an IMRT treatment plan for a radiotherapy system. In one aspect, the method can include providing initial treatment parameters. These parameters can include a number of isotopic beams, a transmission angle for each beam, a prescribed dose for a target, and dose volume histogram constraints. The method can further include determining an initial fluence map including one or more beamlets. The initial fluence map can specify a fluence value for each beamlet. The method can further include determining a delivery sequence for the fluence values in the initial fluence map. The delivery sequence can include one or more apertures formed by the leaves of a collimator. These apertures can have a specified size constrained to substantially less than a maximum size associated with the collimator, when the isotopic beam is near a critical structure. Related apparatus and systems are also described.

Abstract translation: 本文所述的主题提供了用于开发用于放射治疗系统的IMRT治疗计划的方法。 在一个方面，该方法可以包括提供初始治疗参数。 这些参数可以包括多个同位素束，每个束的传播角，目标的规定剂量以及剂量体积直方图约束。 该方法还可以包括确定包括一个或多个子束的初始注量图。 初始注量图可以为每个子束指定注量值。 该方法还可以包括确定初始注量图中的能量密度值的递送序列。 递送顺序可以包括由准直器的叶形成的一个或多个孔。 当同位素束接近临界结构时，这些孔可以具有被限制为基本上小于与准直器相关联的最大尺寸的规定尺寸。 还描述了相关装置和系统。

公开(公告)号：US08952346B2

公开(公告)日：2015-02-10

申请号：US13830794

申请日：2013-03-14

Applicant: ViewRay, Incorporated

Inventor： James F. Dempsey ,  Iwan Kawrykow

IPC: G02B5/00 ,  G21K1/00 ,  H01J1/52 ,  H01J3/00 ,  H01J5/18 ,  H01J29/46 ,  A61N5/10

CPC classification number: A61N5/1031 ,  A61N5/1036 ,  A61N5/1045 ,  A61N5/1071 ,  A61N5/1077

Abstract: The subject matter described herein provides methods for developing an IMRT treatment plan for a radiotherapy system. In one aspect, the method can include providing initial treatment parameters. These parameters can include a number of isotopic beams, a transmission angle for each beam, a prescribed dose for a target, and dose volume histogram constraints. The method can further include determining an initial fluence map including one or more beamlets. The initial fluence map can specify a fluence value for each beamlet. The method can further include determining a delivery sequence for the fluence values in the initial fluence map. The delivery sequence can include one or more apertures formed by the leaves of a collimator. These apertures can have a specified size constrained to substantially less than a maximum size associated with the collimator, when the isotopic beam is near a critical structure. Related apparatus and systems are also described.

Abstract translation: 本文所述的主题提供了用于开发用于放射治疗系统的IMRT治疗计划的方法。 在一个方面，该方法可以包括提供初始治疗参数。 这些参数可以包括多个同位素束，每个束的传播角，目标的规定剂量以及剂量体积直方图约束。 该方法还可以包括确定包括一个或多个子束的初始注量图。 初始注量图可以为每个子束指定注量值。 该方法还可以包括确定初始注量图中的能量密度值的递送序列。 递送顺序可以包括由准直器的叶形成的一个或多个孔。 当同位素束接近临界结构时，这些孔可以具有被限制为基本上小于与准直器相关联的最大尺寸的规定尺寸。 还描述了相关装置和系统。

公开(公告)号：US20140263990A1

公开(公告)日：2014-09-18

申请号：US13801835

申请日：2013-03-13

Applicant: VIEWRAY INCORPORATED

Inventor： Iwan Kawrykow ,  James F. Dempsey

IPC: A61N5/10

CPC classification number: A61N5/1031 ,  A61N5/1045 ,  A61N5/1075 ,  A61N2005/1034 ,  A61N2005/1076

Abstract: Disclosed herein are methods including calibrating a radiotherapy machine to identify an effective radiation source size of a radiation source contained within the radiotherapy machine, the radiation source having a nominal radiation source size, to improve accuracy of a predicted dose profile for one or more radiation beams from the radiation source to further improve accuracy of radiation dose calculation and treatment delivery.

Abstract translation: 这里公开的方法包括校准放射治疗机器以识别包含在放射治疗机器内的辐射源的有效辐射源尺寸，辐射源具有标称辐射源尺寸，以提高一个或多个辐射束的预测剂量分布的精度 从辐射源进一步提高辐射剂量计算和治疗传递的准确性。

公开(公告)号：US20160228728A1

公开(公告)日：2016-08-11

申请号：US15042046

申请日：2016-02-11

Applicant: ViewRay Incorporated

Inventor： James F. Dempsey ,  Iwan Kawrykow

IPC: A61N5/10

CPC classification number: A61N5/1064 ,  A61N5/1037 ,  A61N5/1039 ,  A61N5/1049 ,  A61N5/107 ,  A61N5/1071 ,  A61N2005/1055 ,  A61N2005/1072 ,  G01R33/4808

Abstract: Magnetic resonance (MR) guided radiation therapy (MRgRT) enables control over the delivery of radiation based on patient motion indicated by MR imaging (MRI) images captured during radiation delivery. A method for MRgRT includes: simultaneously using one or more radiation therapy heads to deliver radiation and an MRI system to perform MRI; using a processor to determine whether one or more gates are triggered based on at least a portion of MRI images captured during the delivery of radiation; and in response to determining that one or more gates are triggered based on at least a portion of the MRI images captured during the delivery of radiation, suspending the delivery of radiation.

Abstract translation: 磁共振（MR）引导放射治疗（MRgRT）能够根据辐射传播期间捕获的MR成像（MRI）图像所指示的患者运动来控制辐射传播。 MRgRT的方法包括：同时使用一个或多个放射治疗头传送辐射和MRI系统进行MRI; 使用处理器来基于在辐射传送期间捕获的至少一部分MRI图像来确定是否触发一个或多个门; 并且响应于确定基于在辐射传送期间捕获的MRI图像的至少一部分来触发一个或多个门，暂停辐射的传送。

公开(公告)号：US20140275696A1

公开(公告)日：2014-09-18

申请号：US13830794

申请日：2013-03-14

Applicant: VIEWRAY, INCORPORATED

Inventor： James F. Dempsey ,  Iwan Kawrykow

IPC: A61N5/10

CPC classification number: A61N5/1031 ,  A61N5/1036 ,  A61N5/1045 ,  A61N5/1071 ,  A61N5/1077

Abstract: The subject matter described herein provides methods for developing an IMRT treatment plan for a radiotherapy system. In one aspect, the method can include providing initial treatment parameters. These parameters can include a number of isotopic beams, a transmission angle for each beam, a prescribed dose for a target, and dose volume histogram constraints. The method can further include determining an initial fluence map including one or more beamlets. The initial fluence map can specify a fluence value for each beamlet. The method can further include determining a delivery sequence for the fluence values in the initial fluence map. The delivery sequence can include one or more apertures formed by the leaves of a collimator. These apertures can have a specified size constrained to substantially less than a maximum size associated with the collimator, when the isotopic beam is near a critical structure. Related apparatus and systems are also described.

Abstract translation: 本文所述的主题提供了用于开发用于放射治疗系统的IMRT治疗计划的方法。 在一个方面，该方法可以包括提供初始治疗参数。 这些参数可以包括多个同位素束，每个束的传播角，目标的规定剂量以及剂量体积直方图约束。 该方法还可以包括确定包括一个或多个子束的初始注量图。 初始注量图可以为每个子束指定注量值。 该方法还可以包括确定初始注量图中的能量密度值的递送序列。 递送顺序可以包括由准直器的叶形成的一个或多个孔。 当同位素束接近临界结构时，这些孔可以具有被限制为基本上小于与准直器相关联的最大尺寸的规定尺寸。 还描述了相关装置和系统。