公开(公告)号：US06329530B1

公开(公告)日：2001-12-11

申请号：US09830948

申请日：2001-05-03

申请人： Volker Maywald ,  Adrian Steinmetz ,  Michael Rack ,  Norbert Götz ,  Roland Götz ,  Jochem Henkelmann ,  Heike Becker ,  Juan Jose Aiscar Bayeto

发明人： Volker Maywald ,  Adrian Steinmetz ,  Michael Rack ,  Norbert Götz ,  Roland Götz ,  Jochem Henkelmann ,  Heike Becker ,  Juan Jose Aiscar Bayeto

IPC分类号： C07D23120

CPC分类号： C07D231/20

摘要： The invention relates to a method for the production of 1-substituted 5-hydroxypyrazoles of formula (I) wherein R1 is C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkinyl, C3-C6-cycloalkyl or C1-C4-alkoxy, whereby these groups can be substituted by halogen, C1-C4-alkoxy, phenoxy, C1-C6-alkoxycarbonyl, C1-C6-alkylthiocarbonyl or a cyclic ring system with 3-14 ring atoms, by reacting a) an alkylvinylether of general formula (III) wherein R2 is C1-C6-alkyl or C3-C6-cycloalkyl, with phosgene (IVa), “diphosgene” (IVb) or “triphosgene” (IVc) to form acid chlorides of formula (V), b) transforming said acid chlorides by eliminating hydrogen chloride into the corresponding 3-alkoxyacrylic acid chloride of formula (VI) and c) reacting said acid chloride with hydrazines of formula (VII) wherein R1 has the above cited meaning, to form 5-hydroxypyrazoles of formula (I).

摘要翻译： 本发明涉及制备式（I）的1-取代的5-羟基吡唑的方法，其中R1是C1-C6-烷基，C2-C6-烯基，C2-C6-炔基，C3-C6-环烷基或C1- C4烷氧基，其中这些基团可以被卤素，C 1 -C 4 - 烷氧基，苯氧基，C 1 -C 6 - 烷氧基羰基，C 1 -C 6烷硫基羰基或具有3-14个环原子的环状体系取代，通过使a）烷基乙烯基醚 （IVa），“二光气”（IVb）或“三光气”（IVc））中形成式（V）的酰氯的通式（III）的化合物，其中R2为C1-C6-烷基或C3-C6- b）通过将氯化氢除去相应的式（VI）的3-烷氧基丙烯酰氯，并且c）使所述酰氯与式（Ⅶ）的肼反应，其中R 1具有上述含义，形成5-羟基吡唑 的式（I）化合物。

公开(公告)号：US06392058B1

公开(公告)日：2002-05-21

申请号：US09856201

申请日：2001-05-17

申请人： Volker Maywald ,  Adrian Steinmetz ,  Michael Rack ,  Norbert Götz ,  Roland Götz ,  Jochem Henkelmann ,  Heike Becker ,  Juan Jose Aiscar Bayeto

发明人： Volker Maywald ,  Adrian Steinmetz ,  Michael Rack ,  Norbert Götz ,  Roland Götz ,  Jochem Henkelmann ,  Heike Becker ,  Juan Jose Aiscar Bayeto

IPC分类号： C07D23120

CPC分类号： C07D231/20

摘要： The invention relates to a process for preparing 1-substituted 5- and/or 3-hydroxypyrazoles of the formulae I and II in which R1 is C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C6-cycloalkyl or C1-C4-alkoxy, where these groups may be substituted by halogen, C1-C4-alkoxy, phenoxy, C1-C6-alkoxycarbonyl, C1-C6-alkylthiocarbonyl or by a cyclic ring system having 3-14 ring atoms, which comprises reacting an alkyl 3-alkoxyacrylate of the formula III in which R2, R3 independently of one another are C1-C6-alkyl or C3-C6-cycloalkyl with a hydrazine of the formula IV in which R1 is as defined above a) at a pH of 6-11 to give 5-hydroxypyrazoles of the formula I or b) at a pH of 11-14 to give 3-hydroxypyrazoles of the formula II.

摘要翻译： 本发明涉及一种制备式I和IIin的1-取代的5-和/或3-羟基吡唑的方法，其中R 1为C 1 -C 6 - 烷基，C 2 -C 6 - 烯基，C 2 -C 6 - 炔基，C 3 -C 6 - 环烷基或C 1 -C 4 - 烷氧基，其中这些基团可以被卤素，C 1 -C 4 - 烷氧基，苯氧基，C 1 -C 6 - 烷氧基羰基，C 1 -C 6 - 烷硫基羰基或具有3-14个环原子的环状体系取代， 包括式IIIin的3-烷氧基丙烯酸烷基酯，其中R 2，R 3彼此独立地是C 1 -C 6烷基或C 3 -C 6环烷基与式IVin的肼，其中R 1如上所定义），其pH为6- 11得到式I的5-羟基吡唑）在11-14的pH下，得到式II的3-羟基吡唑。

公开(公告)号：US07034181B1

公开(公告)日：2006-04-25

申请号：US10130821

申请日：2000-11-27

申请人： Roland Götz ,  Norbert Götz ,  Michael Keil ,  Bernd Wolf ,  Adrian Steinmetz ,  Armin Stamm ,  Jochem Henkelmann

发明人： Roland Götz ,  Norbert Götz ,  Michael Keil ,  Bernd Wolf ,  Adrian Steinmetz ,  Armin Stamm ,  Jochem Henkelmann

IPC分类号： C07C51/58

CPC分类号： C07C51/60 ,  C07C63/10

摘要： The invention relates to a method for producing o-chloromethyl benzoic acid chlorides of formula (I), in which R1 to R4 can be the same or different and represent hydrogen C1–C4 alkyl, halogen or trifluoromethyl, by reaction benzo condensed lactones of formula (II), in which R1 to R4 have the above-mentioned meaning, with thionyl chloride. The inventive method is characterized in that the reaction is carried out in the presence of catalytic quantities of a Lewis acid and in the presence of catalytic quantities of a phosphine derivative.

摘要翻译： 本发明涉及一种制备式（I）的邻氯甲基苯甲酰氯的方法，其中R 1至R 4可以相同或不同，表示氢 C 1 -C 4烷基，卤素或三氟甲基，通过反应式（II）的苯并稠合内酯，其中R 1至R 4， SUP> 4 具有上述含义，与亚硫酰氯。 本发明的方法的特征在于反应在催化量的路易斯酸存在下和在催化量的膦衍生物的存在下进行。

公开(公告)号：US06727385B1

公开(公告)日：2004-04-27

申请号：US10130825

申请日：2002-08-12

申请人： Roland Götz ,  Norbert Götz ,  Michael Keil ,  Bernd Wolf ,  Adrian Steinmetz ,  Armin Stamm ,  Jochem Henkelmann

发明人： Roland Götz ,  Norbert Götz ,  Michael Keil ,  Bernd Wolf ,  Adrian Steinmetz ,  Armin Stamm ,  Jochem Henkelmann

IPC分类号： C07C5536

CPC分类号： C07C51/60 ,  C07C63/04 ,  C07C63/10

摘要： A process for preparing o-chloromethylbenzoyl chlorides of the formula I, in which R1 to R4 can be identical or different and are hydrogen, C1-C4-alkyl, halogen or trifluoromethyl, by reacting benzo-fused lactones of the formula II, in which R1 to R4 are as defined above, with thionyl chloride, which comprises carrying out the reaction in the presence of catalytic amounts of boric acid, boric anhydride, borate, boronic acid or boronic acid esters and catalytic amounts of a quaternary ammonium salt is described.

摘要翻译： 制备式I的邻氯甲基苯甲酰氯的方法，其中R 1至R 4可以相同或不同，并且是氢，C 1 -C 4 - 烷基，卤素或三氟甲基，通过使苯并稠合的内酯与 其中R 1至R 4如上所定义的式II与亚硫酰氯反应，其包括在催化量的硼酸，硼酸酐，硼酸盐，硼酸或硼酸的存在下进行反应 描述了酯和催化量的季铵盐。

公开(公告)号：US06734322B1

公开(公告)日：2004-05-11

申请号：US10130826

申请日：2002-05-23

申请人： Armin Stamm ,  Roland Götz ,  Norbert Götz ,  Jochem Henkelmann ,  Heinz-Josef Kneuper ,  Bernd Wolf

发明人： Armin Stamm ,  Roland Götz ,  Norbert Götz ,  Jochem Henkelmann ,  Heinz-Josef Kneuper ,  Bernd Wolf

IPC分类号： C07C5158

CPC分类号： C07C51/09 ,  C07C63/04

摘要： The invention relates to a method for producing o-choromethyl benzenecarbonyl chlorides of formula (I), wherein R1-R4 can be the same or different and stand for hydrogen, C1-C4-alkyl, halogen or trifluoromnethyl, by converting benzocondensed lactones of formula (II), wherein R1-R4 have the aforementioned meaning, with gaseous or liquid phosgene and the dimers or trimers thereof. The inventive method is characterized in that the conversion is carried out in the presence of catalytical amounts of a Lewis acid and catalytical amounts of a phosgenation catalyst

摘要翻译： 本发明涉及一种制备式（I）的邻氯甲基苯甲酰氯的方法，其中R 1 -R 4可以相同或不同，代表氢，C 1 -C 4 - 烷基，卤素或三氟甲基， 通过用气态或液体光气及其二聚体或三聚体转化其中R 1 -R 4具有上述含义的式（II）的苯并二化内酯。 本发明的方法的特征在于转化在催化量的路易斯酸和催化量的光气化催化剂

公开(公告)号：US07091296B2

公开(公告)日：2006-08-15

申请号：US10502647

申请日：2003-02-04

申请人： Harald Meyer ,  Heike Becker ,  Ulrich Erhardt ,  Karl-Heinz Schumacher ,  Martin Jung ,  Jochem Henkelmann

发明人： Harald Meyer ,  Heike Becker ,  Ulrich Erhardt ,  Karl-Heinz Schumacher ,  Martin Jung ,  Jochem Henkelmann

IPC分类号： C08F118/04

CPC分类号： C08F246/00

摘要： The present invention relates to the use of acetophenone or benzophenone derivatives of the formula I where R is unsubstituted or substituted C1 to C3 alkyl, C6 to C10 aryl or aralkyl having from 6 to 10 carbon atoms in the aryl moiety and from 1 to 6 carbon atoms in the alkyl moiety as copolymerizable photoinitiators. The invention further relates to copolymers containing acetophenone or benzophenone derivatives of the formula I in copolymerized form, to processes for preparing said copolymers, and to the use of said copolymers in UV crosslinkable compositions.

摘要翻译： 本发明涉及式I的苯乙酮或二苯甲酮衍生物的用途，其中R是未取代或取代的C 1至C 3烷基，C 6 - 在芳基部分中具有6至10个碳原子的芳族或芳基或烷基部分中的1至6个碳原子作为可共聚的光引发剂。 本发明还涉及含有共聚形式的式I的苯乙酮或二苯甲酮衍生物的共聚物，制备所述共聚物的方法以及所述共聚物在UV可交联组合物中的用途。

公开(公告)号：US06504064B1

公开(公告)日：2003-01-07

申请号：US09884969

申请日：2001-06-21

申请人： Jochem Henkelmann ,  Heike Becker ,  Juan Aiscar ,  Boris A. Trofimov ,  Nina K. Gusarova ,  Ludmilla A. Oparina

发明人： Jochem Henkelmann ,  Heike Becker ,  Juan Aiscar ,  Boris A. Trofimov ,  Nina K. Gusarova ,  Ludmilla A. Oparina

IPC分类号： C07C4106

CPC分类号： C07C41/08 ,  C07C43/16

摘要： Enol ethers of the formula (I) where R1 to R3 are each, independently of one another, hydrogen or a carbon-containing organic radical and R4 is an unsubstituted or substituted alkyl radical, are prepared by reacting alcohols of the formula (II) R4—OH  (II), with alkynes of the formula (IlIa), alkadienes of the formula (IIIb) R1—C≡C—CHR2R3  (IIIa), R1—CH═C═CR2R3  (IIIb) or mixtures thereof, where R1 to R4 are as defined above, in the presence of an alkali metal alkoxide and a polar, aprotic solvent.

摘要翻译： 其中R 1至R 3各自独立地为氢或含碳有机基团且R 4为未取代或取代的烷基的式（I）的烯醇醚通过使式（II）的醇与 在碱金属醇盐和极性非质子溶剂的存在下，式（IIIa）的炔，式（IIIb）的链二烯或其混合物，其中R 1至R 4如上定义。

公开(公告)号：US07670464B2

公开(公告)日：2010-03-02

申请号：US10560135

申请日：2004-06-08

申请人： Katrin Klass ,  Heike Becker ,  Regina Vogelsang ,  Alexander Hauk ,  Markus Siegert ,  Jochem Henkelmann

发明人： Katrin Klass ,  Heike Becker ,  Regina Vogelsang ,  Alexander Hauk ,  Markus Siegert ,  Jochem Henkelmann

IPC分类号： B01D3/36 ,  C07C29/82 ,  C07C41/42 ,  C07C43/16 ,  C07C41/08

CPC分类号： C07C29/82 ,  C07C41/08 ,  C07C41/42 ,  Y10S203/20 ,  C07C43/16 ,  C07C31/08 ,  C07C31/10 ,  C07C31/12

摘要： Process for distillatively separating a mixture containing a vinyl ether of the general formula (I) R1—O—CH═CH2  (I) and alcohol of the general formula (II) R2—OH  (II) in which R1 and R2 are each independently a saturated or unsaturated, aliphatic or cycloaliphatic radical having from 2 to 10 carbon atoms, and in which the alcohol (II) has a boiling point which is at least 1° C. higher, measured at or extrapolated to 0.1 MPa abs, than the vinyl ether (I), by a) passing the mixture into a first distillation column and withdrawing, as a top product, an azeotrope containing vinyl ether (I) and alcohol (II) and, as a bottom product, a stream enriched with the alcohol (II); b) passing the azeotrope containing vinyl ether (I) and alcohol (II) from the first distillation column into a second distillation column which is operated at a pressure which is from 0.01 to 3 MPa higher compared to the first distillation column, and withdrawing, as a bottom product or gaseous sidestream in the stripping section, the vinyl ether (I) and, as a top product, an azeotrope containing vinyl ether (I) and alcohol (II); and c) recycling the azeotrope containing vinyl ether (I) and alcohol (II) from the second distillation column into the first distillation column.

摘要翻译： 蒸馏分离含有通式（I）的R 1 -O-CH = CH 2（I）的乙烯基醚和通式（II）的醇R 2 -OH（II）的混合物的混合物，其中R 1和R 2各自独立地 具有2至10个碳原子的饱和或不饱和的脂肪族或脂环族基团，其中醇（II）的沸点至少为1℃，高于或者外推至0.1MPa abs，比 乙烯基醚（I），通过a）将混合物通入第一蒸馏塔并作为顶部产物取出含乙烯基醚（I）和醇（II）的共沸物，并且作为底部产物，富含 酒精（II）; b）将含有乙烯基醚（I）和乙醇（II）的共沸物从第一蒸馏塔送入第二蒸馏塔，其与第一蒸馏塔相比压力高出0.01至3MPa， 作为汽提部分中的底部产物或气体侧流，乙烯基醚（I）和作为顶部产物的含乙烯基醚（I）和醇（II）的共沸物; 和c）将来自第二蒸馏塔的含乙烯基醚（I）和乙醇（II）的共沸物再循环到第一蒸馏塔中。

公开(公告)号：US20060151310A1

公开(公告)日：2006-07-13

申请号：US10560135

申请日：2004-06-08

申请人： Katrin Klass ,  Heike Becker ,  Regina Vogelsang ,  Alexander Hauk ,  Markus Siegert ,  Jochem Henkelmann

发明人： Katrin Klass ,  Heike Becker ,  Regina Vogelsang ,  Alexander Hauk ,  Markus Siegert ,  Jochem Henkelmann

IPC分类号： C07C41/00 ,  B01D3/00

CPC分类号： C07C29/82 ,  C07C41/08 ,  C07C41/42 ,  Y10S203/20 ,  C07C43/16 ,  C07C31/08 ,  C07C31/10 ,  C07C31/12

摘要： Process for distillatively separating a mixture containing a vinyl ether of the general formula (I) R1—O—CH═CH2   (I) and alcohol of the general formula (II) R2—OH (II) in which R1 and R2 are each independently a saturated or unsaturated, aliphatic or cycloaliphatic radical having from 2 to 10 carbon atoms, and in which the alcohol (II) has a boiling point which is at least 1° C. higher, measured at or extrapolated to 0.1 MPa abs, than the vinyl ether (I), by a) passing the mixture into a first distillation column and withdrawing, as a top product, an azeotrope containing vinyl ether (I) and alcohol (II) and, as a bottom product, a stream enriched with the alcohol (II); b) passing the azeotrope containing vinyl ether (I) and alcohol (II) from the first distillation column into a second distillation column which is operated at a pressure which is from 0.01 to 3 MPa higher compared to the first distillation column, and withdrawing, as a bottom product or gaseous sidestream in the stripping section, the vinyl ether (I) and, as a top product, an azeotrope containing vinyl ether (I) and alcohol (II); and c) recycling the azeotrope containing vinyl ether (I) and alcohol (II) from the second distillation column into the first distillation column.

摘要翻译： 蒸馏分离含有通式（I）的乙烯基醚的混合物的方法<？in-line-formula description =“In-line formula”end =“lead”？> R 1 -O -CH-CH 2（I）<？在线公式描述=“直列式”末端=“尾”→和通式（II）的醇< line-formula description =“In-line Formulas”end =“lead”？> R 2 -O 2（II）<？in-line-formula description =“In-line Formulas”end =“ 其中R 1和R 2各自独立地是具有2至10个碳原子的饱和或不饱和的脂族或脂环族基团，其中醇 （II）的沸点比乙烯基醚（I）具有至少1℃以上测量或外推至0.1MPa abs的沸点，a）将混合物通入第一蒸馏塔并取出，作为 顶部产物，含乙烯基醚（I）和醇（II）的共沸物，和作为底部产物的富含醇（II）的物流; b）将含有乙烯基醚（I）和乙醇（II）的共沸物从第一蒸馏塔送入第二蒸馏塔，其与第一蒸馏塔相比压力高出0.01至3MPa， 作为汽提部分中的底部产物或气体侧流，乙烯基醚（I）和作为顶部产物的含乙烯基醚（I）和醇（II）的共沸物; 和c）将来自第二蒸馏塔的含乙烯基醚（I）和乙醇（II）的共沸物再循环到第一蒸馏塔中。

公开(公告)号：US20060205984A1

公开(公告)日：2006-09-14

申请号：US10554607

申请日：2004-04-16

申请人： Katrin Klass ,  Heike Becker ,  Regina Vogelsang ,  Alexander Hauk ,  Markus Siegert ,  Jochem Henkelmann

发明人： Katrin Klass ,  Heike Becker ,  Regina Vogelsang ,  Alexander Hauk ,  Markus Siegert ,  Jochem Henkelmann

IPC分类号： C07C41/08

CPC分类号： C07C41/08 ,  C07C43/16

摘要： A process for continuously preparing methyl vinyl ether by reacting methanol with ethyne in the liquid phase in the presence of a basic alkali metal or alkaline earth metal compound at a temperature of from 40 to 300° C. and a pressure of from 0.1 to 5 MPa abs, by carrying out the reaction in the absence of a continuous gas phase and at a methyl vinyl ether concentration in the entire liquid phase of ≦30% by weight.

摘要翻译： 在碱性碱金属或碱土金属化合物存在下，在40-300℃的温度和0.1-5MPa的压力下，使甲醇与乙炔在液相中反应连续制备甲基乙烯基醚的方法 abs，通过在不存在连续气相的情况下进行反应，并且在整个液相中的甲基乙烯基醚浓度<30重量％。