公开(公告)号：US09745621B2

公开(公告)日：2017-08-29

申请号：US15239155

申请日：2016-08-17

Applicant: WISYS Technology Foundation, Inc.

Inventor： Aric Martin Opdahl

IPC: G01N21/55 ,  C12Q1/68 ,  G01N21/64 ,  G01N21/552 ,  G01N21/03 ,  G01N21/27 ,  G01N21/17

CPC classification number: C12Q1/6837 ,  C12Q1/6825 ,  G01N21/0332 ,  G01N21/274 ,  G01N21/553 ,  G01N21/6428 ,  G01N21/648 ,  G01N2021/1731 ,  G01N2201/1211

Abstract: A system and method for sensitive measurements of molecular binding as a function of time and temperature provided by a surface plasmon resonance (SPR) instrument producing a stable temperature gradient over the sensor surface. Continuous monitoring of reflected light intensity from different locations of the sensor allows simultaneous measurement of time and temperature dependence of binding interactions.

公开(公告)号：US20170052133A1

公开(公告)日：2017-02-23

申请号：US15239155

申请日：2016-08-17

Applicant: WISYS Technology Foundation, Inc.

Inventor： Aric Martin Opdahl

IPC: G01N25/00 ,  G01N21/64 ,  C12Q1/68 ,  G01N21/552

CPC classification number: C12Q1/6837 ,  C12Q1/6825 ,  G01N21/0332 ,  G01N21/274 ,  G01N21/553 ,  G01N21/6428 ,  G01N21/648 ,  G01N2021/1731 ,  G01N2201/1211

Abstract: A system and method for sensitive measurements of molecular binding as a function of time and temperature provided by a surface plasmon resonance (SPR) instrument producing a stable temperature gradient over the sensor surface. Continuous monitoring of reflected light intensity from different locations of the sensor allows simultaneous measurement of time and temperature dependence of binding interactions.

Abstract translation: 用于通过在传感器表面上产生稳定温度梯度的表面等离子体共振（SPR）仪器提供的作为时间和温度的函数的分子结合的敏感测量的系统和方法。 连续监测来自传感器不同位置的反射光强度，可以同时测量结合相互作用的时间和温度依赖性。