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公开(公告)号：US07323336B2
公开(公告)日：2008-01-29
申请号：US10105733
申请日：2002-03-22
申请人： Walter Callen , Toby Richardson , Gerhard Frey , Carl Miller , Martin Kazaoka , Jay M. Short , Eric J. Mathur
发明人： Walter Callen , Toby Richardson , Gerhard Frey , Carl Miller , Martin Kazaoka , Jay M. Short , Eric J. Mathur
CPC分类号： C12N9/2417 , C12P19/14
摘要： The invention relates to alpha amylases and to polynucleotides encoding the alpha amylases. In addition methods of designing new alpha amylases and methods of use thereof are also provided. The alpha amylases have increased activity and stability at increased pH and temperature.
摘要翻译： 本发明涉及α-淀粉酶和编码α-淀粉酶的多核苷酸。 另外还提供了设计新的α-淀粉酶的方法及其使用方法。 α淀粉酶在增加的pH和温度下具有增加的活性和稳定性。
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2.发明授权Enzymes having alpha amylase activity and methods of making and using them 有权具有α-淀粉酶活性的酶和制备和使用它们的方法公开(公告)号：US07666633B2
公开(公告)日：2010-02-23
申请号：US11400030
申请日：2006-04-06
申请人： Walter Callen , Toby Richardson , Gerhard Frey , Carl Miller , Martin Kazaoka , Jay M. Short , Eric J. Mathur
发明人： Walter Callen , Toby Richardson , Gerhard Frey , Carl Miller , Martin Kazaoka , Jay M. Short , Eric J. Mathur
CPC分类号： C12N9/2417 , A21D8/042 , C12N9/2414 , C12P19/04 , C12P19/14 , C12Y302/01001 , Y02E50/16 , Y02E50/17
摘要： The invention relates to alpha amylases and to polynucleotides encoding the alpha amylases, and methods of making and using them. In addition methods of designing new alpha amylases and methods of use thereof are also provided. The alpha amylases have increased activity and stability at increased pH and temperature.
摘要翻译： 本发明涉及α-淀粉酶和编码α-淀粉酶的多核苷酸，以及制备和使用它们的方法。 另外还提供了设计新的α-淀粉酶的方法及其使用方法。 α淀粉酶在增加的pH和温度下具有增加的活性和稳定性。
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3.发明授权Amylases, nucleic acids encoding them and methods for making and using them 有权淀粉酶，编码它们的核酸和制备和使用它们的方法公开(公告)号：US07659102B2
公开(公告)日：2010-02-09
申请号：US10489510
申请日：2003-03-24
申请人： Walter Callen , Toby Richardson , Gerhard Frey , Carl A. Miller , Martin Kazaoka , Eric J. Mathur , Jay M. Short
发明人： Walter Callen , Toby Richardson , Gerhard Frey , Carl A. Miller , Martin Kazaoka , Eric J. Mathur , Jay M. Short
CPC分类号： C12N9/2411 , C12N9/2417 , C12P19/14
摘要： In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for malting and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of starch into 10 sugars.
摘要翻译： 一方面，本发明涉及具有淀粉酶活性的多肽，编码多肽的多核苷酸，以及用于发芽和使用这些多核苷酸和多肽的方法。 一方面，本发明的多肽可用作淀粉酶，例如α-淀粉酶，以催化淀粉水解成10个糖。
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公开(公告)号：US07273740B2
公开(公告)日：2007-09-25
申请号：US10081739
申请日：2002-02-21
申请人： Walter Callen , Toby Richardson , Gerhard Frey , Carl Miller , Martin Kazaoka , Jay M. Short , Eric Mathur
发明人： Walter Callen , Toby Richardson , Gerhard Frey , Carl Miller , Martin Kazaoka , Jay M. Short , Eric Mathur
CPC分类号： C12N9/2417 , A21D8/042 , C12N9/2414 , C12P19/04 , C12P19/14 , C12Y302/01001 , Y02E50/16 , Y02E50/17
摘要： The invention relates to alpha amylases and to polynucleotides encoding the alpha amylases. In addition methods of designing new alpha amylases and methods of use thereof are also provided. The alpha amylases have increased activity and stability at increased pH and temperature.
摘要翻译： 本发明涉及α-淀粉酶和编码α-淀粉酶的多核苷酸。 另外还提供了设计新的α-淀粉酶的方法及其使用方法。 α淀粉酶在增加的pH和温度下具有增加的活性和稳定性。
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5.发明申请公开(公告)号：US20100209995A1
公开(公告)日：2010-08-19
申请号：US12697907
申请日：2010-02-01
申请人： Walter Callen , Toby Richardson , Gerhard Frey , Carl Miller , Martin Kazaoka , Eric Mathur , Jay Short
发明人： Walter Callen , Toby Richardson , Gerhard Frey , Carl Miller , Martin Kazaoka , Eric Mathur , Jay Short
IPC分类号： C12N9/26
CPC分类号： C12N9/2411 , C12N9/2417 , C12P19/14
摘要： In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of starch into sugars.
摘要翻译： 一方面，本发明涉及具有淀粉酶活性的多肽，编码多肽的多核苷酸，以及制备和使用这些多核苷酸和多肽的方法。 在一个方面，本发明的多肽可用作淀粉酶，例如α-淀粉酶，以催化淀粉水解成糖。
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6.发明申请Enyzmes having alpha amylase activity and methods of making and using them 有权具有α淀粉酶活性的Enyzmes及其制备和使用方法公开(公告)号：US20060234280A1
公开(公告)日：2006-10-19
申请号：US11400030
申请日：2006-04-06
申请人： Walter Callen , Toby Richardson , Gerhard Frey , Carl Miller , Martin Kazaoka , Jay Short , Eric Mathur
发明人： Walter Callen , Toby Richardson , Gerhard Frey , Carl Miller , Martin Kazaoka , Jay Short , Eric Mathur
IPC分类号： C12Q1/68 , A23K1/18 , C07H21/04 , C12P21/06 , C12P19/02 , C12P7/06 , C12N9/32 , C12N1/21 , C11D3/386
CPC分类号： C12N9/2417 , A21D8/042 , C12N9/2414 , C12P19/04 , C12P19/14 , C12Y302/01001 , Y02E50/16 , Y02E50/17
摘要： The invention relates to alpha amylases and to polynucleotides encoding the alpha amylases, and methods of making and using them. In addition methods of designing new alpha amylases and methods of use thereof are also provided. The alpha amylases have increased activity and stability at increased pH and temperature.
摘要翻译： 本发明涉及α-淀粉酶和编码α-淀粉酶的多核苷酸，以及制备和使用它们的方法。 另外还提供了设计新的α-淀粉酶的方法及其使用方法。 α淀粉酶在增加的pH和温度下具有增加的活性和稳定性。
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7.发明申请Amylases, nucleic acids encoding them and methods for making and using them 有权淀粉酶，编码它们的核酸和制备和使用它们的方法公开(公告)号：US20050176000A1
公开(公告)日：2005-08-11
申请号：US10489510
申请日：2003-03-24
申请人： Walter Callen , Toby Richardson , Gerhard Frey , Carl Miller , Martin Kazaoka , Eric Mathur , Jay Short
发明人： Walter Callen , Toby Richardson , Gerhard Frey , Carl Miller , Martin Kazaoka , Eric Mathur , Jay Short
CPC分类号： C12N9/2411 , C12N9/2417 , C12P19/14
摘要： In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for malting and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of starch into 10 sugars.
摘要翻译： 一方面，本发明涉及具有淀粉酶活性的多肽，编码多肽的多核苷酸，以及用于发芽和使用这些多核苷酸和多肽的方法。 一方面，本发明的多肽可用作淀粉酶，例如α-淀粉酶，以催化淀粉水解成10个糖。
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公开(公告)号：US08338131B2
公开(公告)日：2012-12-25
申请号：US12697907
申请日：2010-02-01
申请人： Walter Callen , Toby Richardson , Gerhard Frey , Carl Miller , Martin Kazaoka , Eric Mathur , Jay Short
发明人： Walter Callen , Toby Richardson , Gerhard Frey , Carl Miller , Martin Kazaoka , Eric Mathur , Jay Short
CPC分类号： C12N9/2411 , C12N9/2417 , C12P19/14
摘要： In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of starch into sugars.
摘要翻译： 一方面，本发明涉及具有淀粉酶活性的多肽，编码多肽的多核苷酸，以及制备和使用这些多核苷酸和多肽的方法。 在一个方面，本发明的多肽可用作淀粉酶，例如α-淀粉酶，以催化淀粉水解成糖。
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