Composition and method for treating cancer
    3.
    发明授权
    Composition and method for treating cancer 失效
    用于治疗癌症的组合物和方法

    公开(公告)号:US07074825B2

    公开(公告)日:2006-07-11

    申请号:US10383811

    申请日:2003-03-07

    IPC分类号: A61K31/35 A61K31/335

    CPC分类号: A61K45/06

    摘要: A composition and an associated method of treating cancer cells by impeding cancer cell growth with the composition are disclosed. The composition includes at least a first and a second HMG-CoA reductase inhibitor, wherein the total amount of the first and second HMG-CoA reductase inhibitors is effective in synergistically impeding cancer cell growth and wherein the cancer cell growth synergistic impedance from the total amount of the first and second HMG-CoA reductase inhibitors is greater than a theoretical additive effect from the combined first and second HMG-CoA reductase inhibitors. The present composition does not simultaneously contain both a tocotrienol and an ionone when the composition contains only a first and a second HMG-CoA reductase inhibitor. The method includes treating cancer cells with the claimed composition to impede cancer cell growth.

    摘要翻译: 公开了通过阻止癌细胞生长与组合物来治疗癌细胞的组合物和相关方法。 所述组合物包含至少第一和第二HMG-CoA还原酶抑制剂,其中所述第一和第二HMG-CoA还原酶抑制剂的总量有效协同地阻碍癌细胞生长,并且其中所述癌细胞生长协同阻抗从总量 的第一和第二HMG-CoA还原酶抑制剂大于来自组合的第一和第二HMG-CoA还原酶抑制剂的理论叠加效应。 当组合物仅含有第一和第二HMG-CoA还原酶抑制剂时,本发明组合物不同时含有生育三烯酚和紫罗酮。 该方法包括用所要求保护的组合物治疗癌细胞以阻止癌细胞生长。

    Acyclic monoterpenoid derivatives
    4.
    发明授权
    Acyclic monoterpenoid derivatives 失效
    无环单萜衍生物

    公开(公告)号:US06303654B1

    公开(公告)日:2001-10-16

    申请号:US09263622

    申请日:1999-03-05

    IPC分类号: A01N3712

    CPC分类号: A61K31/216 A61K31/00

    摘要: A method of inhibiting or preventing the growth of tumor cells is disclosed. In one embodiment, this method comprises the step of administering a compound selected from the group consisting of citracetal, citral dimethyl acetal, citral diethyl acetal, geranyl benzoate, geranyl tiglate, geranyl anthranilate, farnesyl benzoate, farnesyl anthranilate, farnesyl tiglate, farnesyl acetate and combinations thereof to a human tumor patient, wherein the amount is effective to reduce or inhibit tumor growth by at least 50%.

    摘要翻译: 公开了抑制或预防肿瘤细胞生长的方法。 在一个实施方案中,该方法包括施用选自柠檬醛,柠檬醛二甲基缩醛,柠檬醛二乙基缩醛,香叶基苯甲酸酯,香叶基邻苯二甲酸盐,香叶基邻氨苯甲酸酯,法尼基苯甲酸酯,邻氨基苯甲酸茴香酯,法尼基酯,醋酸法呢酯和 它们与人类肿瘤患者的组合,其中该量有效地减少或抑制肿瘤生长至少50%。

    Method of suppressing tumor growth with combinations of isoprenoids and statins
    8.
    发明授权
    Method of suppressing tumor growth with combinations of isoprenoids and statins 失效
    用类异戊二烯和他汀类药物组合抑制肿瘤生长的方法

    公开(公告)号:US06441029B1

    公开(公告)日:2002-08-27

    申请号:US09587737

    申请日:2000-06-05

    申请人: Charles E. Elson

    发明人: Charles E. Elson

    IPC分类号: A61K3135

    摘要: A method of inhibiting the growth of tumor cells is disclosed. In one embodiment, this method comprises the step of exposing tumor cells to an effective amount of a composition comprising at least two compounds selected from the group consisting of tocotrienols, statins and ionones.

    摘要翻译: 公开了抑制肿瘤细胞生长的方法。 在一个实施方案中,该方法包括将肿瘤细胞暴露于有效量的包含至少两种选自生育三烯酚,他汀类和紫罗兰酮的化合物的组合物的步骤。