公开(公告)号：US20240226845A1

公开(公告)日：2024-07-11

申请号：US18407660

申请日：2024-01-09

Applicant: Waters Technologies Corporation

Inventor： Matthew Lauber ,  Nicole Lawrence ,  Daniel Walsh ,  Jessica Field

IPC: B01J20/10 ,  B01J20/28 ,  B01J20/30 ,  G01N21/33 ,  G01N30/02 ,  G01N30/88

CPC classification number: B01J20/103 ,  B01J20/28016 ,  B01J20/28045 ,  B01J20/3085 ,  G01N21/33 ,  G01N30/88 ,  G01N2030/027 ,  G01N2030/8827

Abstract: Provided herein are compositions, kits and methods that may be useful for improving the efficiency of solid phase extraction to separate oligonucleotides from a complex matrix. Particularly, the present technology relates to a sorbent material including porous particles, the surface of which is modified with a ligand that includes one or more bridging alkyl substituted amines and at least two siloxyl terminal groups.