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    METHODS FOR DIRECTING DIFFERENTIATION OF CLONOGENIC NEURAL STEM CELLS WITH COUMARINS
    2.
    发明申请
    METHODS FOR DIRECTING DIFFERENTIATION OF CLONOGENIC NEURAL STEM CELLS WITH COUMARINS 审中-公开
    用COUMARIN指导克隆性神经干细胞分化的方法

    公开(公告)号：US20090170930A1

    公开(公告)日：2009-07-02

    申请号：US12400756

    申请日：2009-03-09

    申请人： Cheng HE ,  Weidong ZHANG ,  Xiaohui XU ,  Wei ZHANG ,  Juan SU ,  Chuan ZHANG

    发明人： Cheng HE ,  Weidong ZHANG ,  Xiaohui XU ,  Wei ZHANG ,  Juan SU ,  Chuan ZHANG

    IPC分类号： A61K31/35

    CPC分类号： A61K31/37

    摘要： A method for promoting differentiation of clonogenic neural stem cells (NSCs), comprising administering to a patient in the need of such promoting a coumarin compound represented by formula I or by formula II. The representative coumarin compounds include 7-hydroxycoumarin, daphnoretin, scopoletin, edgeworin, aesculetin and esculetin-6-β-D-glucopyranoside. The coumarin compounds showed significant activity of directing the differentiation of NSCs in pharmacological test and thereof could be used to prepare drugs to direct NSCs differentiated to oligodendrocyte progenitor cells (OPCs) for the treatment of demyelinating diseases or spinal cord injury. The drug could be a pure coumarin compound or a pharmaceutical composition comprising a therapeutical dose of a coumarin compound as active ingredients and a pharmaceutically-acceptable carrier. The content of the active ingredients in the pharmaceutical composition is between 0.1% and 99.5% by weight.

    摘要翻译： 一种促进克隆型神经干细胞（NSCs）分化的方法，包括对需要这样促进由式I或式II表示的香豆素化合物的患者施用。 代表性的香豆素化合物包括7-羟基香豆素，芫花tin tin，scopoletin，edgeworin，七叶苷和七叶苷-6-β-D-吡喃葡萄糖苷。 香豆素化合物在药理学试验中显示出指导NSCs分化的显着活性，并且其可用于制备药物以指导分化为少突胶质细胞祖细胞（OPCs）的NSCs用于治疗脱髓鞘疾病或脊髓损伤。 药物可以是纯香豆素化合物或包含治疗剂量的香豆素化合物作为活性成分和药学上可接受的载体的药物组合物。 药物组合物中活性成分的含量为0.1〜99.5重量％。

    BEVERAGE BREWING POT
    4.
    发明公开
    BEVERAGE BREWING POT 审中-公开

    公开(公告)号：US20240148171A1

    公开(公告)日：2024-05-09

    申请号：US18412896

    申请日：2024-01-15

    申请人： Weidong ZHANG

    发明人： Weidong ZHANG ,  Wenbiao XIAO

    IPC分类号： A47G19/14 ,  A47J31/20 ,  A47J31/46 ,  A47J31/52

    CPC分类号： A47G19/14 ,  A47J31/20 ,  A47J31/468 ,  A47J31/525 ,  A23F3/18

    摘要： A beverage brewing pot includes a first pot liner, a second pot liner, a water-air pump and a controller. A brewing chamber is arranged between the first pot liner and the second pot liner. The first pot liner, the second pot liner and the brewing chamber are in communication. At least the first pot liner is sealed during operation. A first water-level sensor is provided at the top of the first pot liner, and a second water-level sensor is provided at the top of the second pot liner. The controller controls the water-air pump to feed air to the first pot liner to direct the water to flow into the second pot liner. The controller controls the water-air pump to operate reversely, such that the water in the second pot liner is pumped back to the first pot liner.

    BEVERAGE BREWING POT AND BEVERAGE BREWING METHOD USING SAME
    5.
    发明申请
    BEVERAGE BREWING POT AND BEVERAGE BREWING METHOD USING SAME 有权

    公开(公告)号：US20210386225A1

    公开(公告)日：2021-12-16

    申请号：US17354054

    申请日：2021-06-22

    申请人： Weidong Zhang

    发明人： Weidong ZHANG ,  Wenbiao XIAO

    IPC分类号： A47G19/14 ,  A47J31/20 ,  A47J31/46 ,  A47J31/52

    摘要： A beverage brewing pot and a beverage brewing method using the same. The brewing pot includes a first pot liner, a second pot liner, a water-air pump and a controller. A brewing chamber is arranged between the first pot liner and the second pot liner. The first pot liner, the second pot liner and the brewing chamber are in communication. At least the first pot liner is sealed during operation. A first water-level sensor is provided at the top of the first pot liner, and a second water-level sensor is provided at the top of the second pot liner. The controller controls the water-air pump to feed air to the first pot liner to direct the water to flow into the second pot liner. The controller controls the water-air pump to operate reversely, such that the water in the second pot liner is pumped back to the first pot liner.

    Method and System for Detecting QoS Anomaly
    6.
    发明申请
    Method and System for Detecting QoS Anomaly 审中-公开
    检测QoS异常的方法和系统

    公开(公告)号：US20100246432A1

    公开(公告)日：2010-09-30

    申请号：US12796136

    申请日：2010-06-08

    申请人： Weidong ZHANG ,  Yandong CAO ,  Jiying DUI

    发明人： Weidong ZHANG ,  Yandong CAO ,  Jiying DUI

    IPC分类号： H04L12/26

    CPC分类号： H04L43/16 ,  H04L41/5003 ,  H04L41/5009 ,  H04L43/0829 ,  H04L43/0852 ,  H04L43/106

    摘要： A method for detecting QoS anomaly is provided. The method includes obtaining a QoS index of data stream transmission of a parent peer, and detecting QoS anomaly of the parent peer according to the QoS index and a corresponding QoS index threshold. A method for detecting factors causing QoS anomaly is also provided. The method includes detecting whether QoS of an associated peer is abnormal or not, counting a QoS anomaly proportion of the associated peer statistically, and determining factors causing QoS anomaly according to the anomaly proportion of the associated peer. Correspondingly, a system for detecting QoS anomaly and a system for detecting factors causing QoS anomaly are also provided. Thus, the QoS anomaly information is detected, and the factors causing the QoS anomaly are also detected, so as to ensure that the QoS anomaly information is precisely detected in a P2P system, and the QoS in the system is indeed guaranteed.

    摘要翻译： 提供了一种检测QoS异常的方法。 该方法包括获取父对等体的数据流传输的QoS索引，并根据QoS索引和对应的QoS索引阈值检测父对等体的QoS异常。 还提供了一种检测导致QoS异常的因素的方法。 该方法包括检测相关对等体的QoS是否异常，统计相关对等体的QoS异常比例，根据相关对等体的异常比例确定导致QoS异常的因素。 相应地，还提供了用于检测QoS异常的系统和用于检测导致QoS异常的因素的系统。 因此，检测到QoS异常信息，并且还检测到导致QoS异常的因素，以确保在P2P系统中精确地检测到QoS异常信息，并确保系统中的QoS。