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公开(公告)号:US20120295859A1
公开(公告)日:2012-11-22
申请号:US13452962
申请日:2012-04-23
申请人: Weidong ZHANG , Jin HUANG , Lei SHAN , Honglin LI , Liyan WANG , Shoude ZHANG , Weiqiang LU , Juan SU , Tong CHEN
发明人: Weidong ZHANG , Jin HUANG , Lei SHAN , Honglin LI , Liyan WANG , Shoude ZHANG , Weiqiang LU , Juan SU , Tong CHEN
IPC分类号: A61K31/7048 , A61P33/06
CPC分类号: A61K31/7048 , Y02A50/411
摘要: A method for treatment of malaria including administering to a patient in need thereof a flavonoid glycoside compound.
摘要翻译: 一种治疗疟疾的方法,包括向有需要的患者施用类黄酮糖苷化合物。
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公开(公告)号:US08846627B2
公开(公告)日:2014-09-30
申请号:US13452962
申请日:2012-04-23
申请人: Weidong Zhang , Jin Huang , Lei Shan , Honglin Li , Liyan Wang , Shoude Zhang , Weiqiang Lu , Juan Su , Tong Chen
发明人: Weidong Zhang , Jin Huang , Lei Shan , Honglin Li , Liyan Wang , Shoude Zhang , Weiqiang Lu , Juan Su , Tong Chen
IPC分类号: A61K31/70 , A61K31/7048
CPC分类号: A61K31/7048 , Y02A50/411
摘要: A method for treatment of malaria including administering to a patient in need thereof a flavonoid glycoside compound.
摘要翻译: 一种治疗疟疾的方法,包括向有需要的患者施用类黄酮糖苷化合物。
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3.
公开(公告)号:US08962339B2
公开(公告)日:2015-02-24
申请号:US13521047
申请日:2010-12-06
申请人: Xiaojun Peng , Jiangli Fan , Honglin Li , Jingyun Wang , Shiguo Sun
发明人: Xiaojun Peng , Jiangli Fan , Honglin Li , Jingyun Wang , Shiguo Sun
IPC分类号: G01N21/76 , C07D491/107 , C07F9/6561 , C09K11/06 , G01N21/64 , G01N21/75 , G01N21/77
CPC分类号: C07F9/6561 , C09K11/06 , C09K2211/1007 , C09K2211/1029 , C09K2211/1088 , G01N21/643 , G01N21/75 , G01N2021/6439 , G01N2021/7786
摘要: The present invention discloses a fluorescent probe compound which solved the problem of fluorescence quenching by Pd2+, and its preparation method and use as well. Excitation and emission wavelengths of the probe compound are in visible light region. The probe compound is highly sensitive and displays good selectivity for Pd2+ in near-neutral pH range. In detection of Pd2+ in 0-10 ppb level, fluorescence is evidently enhanced, and Pd2+ in the level as low as 5 nM can be detected. Fluorescence intensity is well linearly correlated to Pd2+ concentration. The probe compound can be used for detection of contaminating palladium and residual palladium in drug, soil, water sample and reactor.
摘要翻译: 本发明公开了一种解决Pd2 +荧光猝灭问题的荧光探针化合物及其制备方法和用途。 探针化合物的激发和发射波长处于可见光区域。 探针化合物是高度敏感的,并且在近中性pH范围内对Pd2 +显示出良好的选择性。 在检测到0-10ppb级别的Pd2 +时,荧光显着增强,并且可以检测到低至5nM的水平的Pd2 +。 荧光强度与Pd2 +浓度呈线性相关。 探针化合物可用于检测药物,土壤,水样和反应器中污染的钯和残留的钯。
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4.
公开(公告)号:US20120288947A1
公开(公告)日:2012-11-15
申请号:US13521047
申请日:2010-12-06
申请人: Xiaojun Peng , Jiangli Fan , Honglin Li , Jingyun Wang , Shiguo Sun
发明人: Xiaojun Peng , Jiangli Fan , Honglin Li , Jingyun Wang , Shiguo Sun
IPC分类号: G01N21/76 , C07D491/107
CPC分类号: C07F9/6561 , C09K11/06 , C09K2211/1007 , C09K2211/1029 , C09K2211/1088 , G01N21/643 , G01N21/75 , G01N2021/6439 , G01N2021/7786
摘要: The present invention discloses a fluorescent probe compound which solved the problem of fluorescence quenching by Pd2+, and its preparation method and use as well. Excitation and emission wavelengths of the probe compound are in visible light region. The probe compound is highly sensitive and displays good selectivity for Pd2 in near-neutral pH range. In detection of Pd2 in 0-10 ppb level, fluorescence is evidently enhanced, and Pd2 in the level as low as 5 nM can be detected. Fluorescence intensity is well linearly correlated to Pd2 concentration. The probe compound can be used for detection of contaminating palladium and residual palladium in drug, soil, water sample and reactor.
摘要翻译: 本发明公开了一种解决Pd2 +荧光猝灭问题的荧光探针化合物及其制备方法和用途。 探针化合物的激发和发射波长处于可见光区域。 探针化合物是高度敏感的,对近中性pH范围内的Pd2显示出良好的选择性。 在检测到0-10ppb级别的Pd2时,荧光显着增强,可以检测到低至5nM的Pd2。 荧光强度与Pd2浓度呈线性相关。 探针化合物可用于检测药物,土壤,水样和反应器中污染的钯和残留的钯。
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