公开(公告)号：US20070244328A1

公开(公告)日：2007-10-18

申请号：US11628818

申请日：2005-06-30

申请人： Wie Wang ,  Jian Wang ,  Hao Li

发明人： Wie Wang ,  Jian Wang ,  Hao Li

IPC分类号： C07D207/10 ,  C07C205/04 ,  C07C381/00 ,  C07D315/00 ,  C07F11/00 ,  C07D333/22 ,  C07D211/00 ,  C07C45/00

CPC分类号： C07D207/09 ,  C07B2200/07 ,  C07C45/511 ,  C07C45/54 ,  C07C45/72 ,  C07C45/74 ,  C07C47/56 ,  C07C49/203 ,  C07C49/21 ,  C07C49/235 ,  C07C49/647 ,  C07C49/653 ,  C07C49/683 ,  C07C49/697 ,  C07C49/753 ,  C07C49/86 ,  C07C67/343 ,  C07C201/12 ,  C07C205/44 ,  C07C205/45 ,  C07C213/02 ,  C07C215/42 ,  C07C227/32 ,  C07C239/20 ,  C07C253/30 ,  C07C319/14 ,  C07C391/02 ,  C07C2601/08 ,  C07C2601/14 ,  C07C2601/16 ,  C07C2601/18 ,  C07D309/30 ,  C07D317/72 ,  C07D333/22 ,  C07C49/258 ,  C07C49/245 ,  C07C69/76 ,  C07C323/22 ,  C07C255/56 ,  C07C229/22 ,  C07C229/28 ,  C07C229/30 ,  C07C229/36

摘要： The present invention pertains generally to compositions comprising organocatalysts that facilitate stereo-selective reactions and the method of their synthesis and use. Particularly, the invention relates to metal-free organocatalysts for facilitation of stereo-selective reactions, and the method of their synthesis and use. These compounds have the structure of the Formulas (I) and (II). Where X is independently selected from CH2, N—Ra, O, S or C═O; Y is CH2, N—Ra, O, S or C═O, with the proviso that at least one of X or Y is CH2, and preferably both of X and Y are CH2; Ra is H, an optionally substituted C1-C12 alkyl, preferably an optionally substituted C1-C6alkyl including a C3-C6 cyclic alkyl group, or an optionally substituted aryl group, preferably an optionally substituted phenyl group; Rb is H, an optionally substituted C1-C12 alkyl, preferably an optionally substituted C1-C6 acyclic or a a C3-C6 cyclic alkyl group, CIIO, N(Me)O, CO(S)Ra or the group of Formula (III). Where Rc and Rd are each independently H, F, Cl, an optionally substituted C1-C20 alkyl, preferably an optionally substituted C1-C12 alkyl, more preferably a C1-C6 alkyl, and an optionally substituted aryl group, or together Rc and Rd form an optionally substituted carbocyclic or optionally substituted heterocyclic ring; R1 is OH, OR, NR′R″, NHC(═O)R, NHSO2R; R2 is H, F, Cl, an optionally substituted C1-C20 alkyl, preferably an optionally substituted C1C6 alkyl, an optionally substituted aryl group or a ═O group (which establishes a carbonyl group with the carbon to which ═O is attached; R3 is H, OH, F, Cl, Br, I, Cl, an optionally substituted C1-C20 alkyl, alkenyl or alkynyl (“hydrocarbyl”) group, preferably an optionally substituted C1-C6 alkyl, or an optionally substituted aryl, such that the carbon to which R3 is attached has an R or S configuration; R is II, an optionally substituted C1-C20 alkyl, preferably an optionally substituted C1-C6 alkyl, or an optionally substituted aryl group, R′ and R″ are each independently H, an optionally substituted C1-C20 alkyl group, preferably an optionally substituted C1-C6 alkyl, or an optionally substituted aryl group; or together R′ and R″ form an optionally substituted heterocyclic, preferably a 4 to 7 membered optionally substituted heterocyclic group or an optionally substituted heteroaryl ring with the nitrogen to which R′ and R″ are attached; and wherein said compound is free from a metal catalyst.

公开(公告)号：US06867162B2

公开(公告)日：2005-03-15

申请号：US10717094

申请日：2003-11-19

申请人： Bi Le-Khac ,  Wie Wang

发明人： Bi Le-Khac ,  Wie Wang

IPC分类号： C08G18/22 ,  B01J27/26 ,  B01J31/22 ,  C08G65/10 ,  C08G65/26 ,  C08G65/28 ,  B01J31/00 ,  B01J31/02 ,  B01J31/06

CPC分类号： B01J31/165 ,  B01J27/26 ,  B01J31/1805 ,  B01J31/2208 ,  B01J31/2234 ,  B01J31/26 ,  B01J31/28 ,  B01J2231/10 ,  B01J2531/0205 ,  B01J2531/26 ,  B01J2531/827 ,  B01J2531/84 ,  B01J2531/845 ,  C08G65/2663

摘要： The present invention is directed to double metal cyanide catalysts (“DMC”) which are prepared by combining i) at least one metal salt; ii) at least one metal cyanide salt; iii) at least one organic complexing ligand; iv) at least one alkali metal salt; and, optionally, v) at least one functionalized polymer under conditions sufficient to form a catalyst; and adding a sufficient amount of the at least one alkali metal salt to the catalyst so formed in an amount such that the catalyst includes the at least one alkali metal salt in an amount of from about 0.4 to about 6 wt. % based on the total weight of the catalyst. The polyols produced in the presence of the catalysts of the present invention have reduced levels of high molecular weight tail.

摘要翻译： 本发明涉及通过组合i）至少一种金属盐制备的双金属氰化物催化剂（“DMC”）， ii）至少一种金属氰化物盐; iii）至少一种有机络合配体; iv）至少一种碱金属盐; 和任选地，v）在足以形成催化剂的条件下的至少一种官能化聚合物; 并向所形成的催化剂中加入足量的至少一种碱金属盐，其量使得催化剂包含至少一种碱金属盐，其量为约0.4至约6wt。 ％，基于催化剂的总重量。 在本发明的催化剂存在下制备的多元醇具有降低的高分子量尾料水平。