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1.发明申请DURABLE HIGH STRENGTH POLYMER COMPOSITE SUITABLE FOR IMPLANT AND ARTICLES PRODUCED THEREFROM 有权耐久高强度聚合物复合材料适用于生产的植入物及其制品公开(公告)号：US20120253453A1
公开(公告)日：2012-10-04
申请号：US13078774
申请日：2011-04-01
IPC分类号： A61F2/82
CPC分类号： A61F2/24 , A61F2/2412 , A61F2/2415 , A61F2/2418 , A61F2/2472 , A61F2/2475 , A61F2210/0076 , A61F2220/005 , A61F2230/00 , A61F2230/0006 , A61F2230/0013 , A61F2230/0054 , A61L27/025 , A61L27/40 , A61L27/48 , A61L27/507 , A61L2430/20 , C08L27/00
摘要： A thin, biocompatible, high-strength, composite material is disclosed that is suitable for use in various implanted configurations. In one aspect, the composite material maintains flexibility in high-cycle flexural applications, making it particularly applicable to high-flex implants such as heart pacing lead or heart valve leaflet. The composite material includes a porous expanded fluoropolymer membrane and an elastomer, wherein the elastomer fills substantially all of the pores of the porous expanded fluoropolymer, and the composite material comprising less than about 80% fluoropolymer by weight.
摘要翻译： 公开了一种适用于各种植入构型的薄的，生物相容的，高强度的复合材料。 在一个方面，复合材料在高周期弯曲应用中保持灵活性，使其特别适用于诸如心脏起搏引线或心脏瓣膜小叶的高柔性植入物。 复合材料包括多孔膨胀氟聚合物膜和弹性体，其中弹性体基本上填充多孔膨胀氟聚合物的所有孔，并且复合材料包含按重量计小于约80％的含氟聚合物。
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2.发明授权Durable high strength polymer composite suitable for implant and articles produced therefrom 有权耐用的高强度聚合物复合材料适用于植入物和由其制造的制品公开(公告)号：US08961599B2
公开(公告)日：2015-02-24
申请号：US13078774
申请日：2011-04-01
CPC分类号： A61F2/24 , A61F2/2412 , A61F2/2415 , A61F2/2418 , A61F2/2472 , A61F2/2475 , A61F2210/0076 , A61F2220/005 , A61F2230/00 , A61F2230/0006 , A61F2230/0013 , A61F2230/0054 , A61L27/025 , A61L27/40 , A61L27/48 , A61L27/507 , A61L2430/20 , C08L27/00
摘要： A thin, biocompatible, high-strength, composite material is disclosed that is suitable for use in various implanted configurations. In one aspect, the composite material maintains flexibility in high-cycle flexural applications, making it particularly applicable to high-flex implants such as heart pacing lead or heart valve leaflet. The composite material includes a porous expanded fluoropolymer membrane and an elastomer, wherein the elastomer fills substantially all of the pores of the porous expanded fluoropolymer, and the composite material comprising less than about 80% fluoropolymer by weight.
摘要翻译： 公开了一种适用于各种植入构型的薄的，生物相容的，高强度的复合材料。 在一个方面，复合材料在高周期弯曲应用中保持灵活性，使其特别适用于诸如心脏起搏引线或心脏瓣膜小叶的高柔性植入物。 复合材料包括多孔膨胀氟聚合物膜和弹性体，其中弹性体基本上填充多孔膨胀氟聚合物的所有孔，并且复合材料包含按重量计小于约80％的含氟聚合物。
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3.发明授权Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom 有权耐用的多层高强度聚合物复合材料，适用于植入物和由其制造的制品公开(公告)号：US08945212B2
公开(公告)日：2015-02-03
申请号：US13485823
申请日：2012-05-31
CPC分类号： A61F2/2403 , A61F2/24 , A61F2/2415 , A61F2210/0076 , A61F2230/00 , A61F2240/001 , A61F2240/005 , A61L27/34 , A61L27/48 , A61L27/507 , A61L27/56 , A61L2420/04 , A61L2420/08 , A61L2430/20 , Y10T29/49412 , C08L27/18
摘要： A thin, biocompatible, high-strength, composite material is disclosed that is suitable for use in various implanted configurations. The composite material maintains flexibility in high-cycle flexural applications, making it particularly applicable to high-flex implants such as heart pacing lead or heart valve leaflet. The composite material includes at least one porous expanded fluoropolymer layer and an elastomer substantially filling substantially all of the pores of the porous expanded fluoropolymer.
摘要翻译： 公开了一种适用于各种植入构型的薄的，生物相容的，高强度的复合材料。 复合材料在高周期弯曲应用中保持灵活性，使其特别适用于高柔性植入物，如心脏起搏引线或心脏瓣膜小叶。 复合材料包括至少一个多孔膨胀氟聚合物层和基本上填充多孔膨胀氟聚合物的基本上所有孔的弹性体。
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公开(公告)号：US20130096606A1
公开(公告)日：2013-04-18
申请号：US13448277
申请日：2012-04-16
申请人： William C. Bruchman , Edward H. Cully , Cody L. Hartman , Joshua J. Lovekamp , Benjamin M. Trapp
发明人： William C. Bruchman , Edward H. Cully , Cody L. Hartman , Joshua J. Lovekamp , Benjamin M. Trapp
IPC分类号： A61F2/01
CPC分类号： A61F2/013 , A61F2002/016 , A61F2002/018 , A61F2210/0014 , A61F2230/0006 , A61F2230/0067 , A61F2230/0069 , A61F2230/008 , A61F2250/0023
摘要： According to one aspect of the disclosure, an embolic protection device is provided comprising an elongate element having a deflector at its distal end. The embolic protection device is generally configured to redirect and/or funnel embolic debris and permit at least a portion of the blood, no longer containing the redirected and/or funneled embolic debris, to perfuse the surrounding vasculature and/or tissue.
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5.发明申请DURABLE MULTI-LAYER HIGH STRENGTH POLYMER COMPOSITE SUITABLE FOR IMPLANT AND ARTICLES PRODUCED THEREFROM 有权耐久多层高强度聚合物复合材料适用于生产的植物和植物公开(公告)号：US20120323315A1
公开(公告)日：2012-12-20
申请号：US13485823
申请日：2012-05-31
CPC分类号： A61F2/2403 , A61F2/24 , A61F2/2415 , A61F2210/0076 , A61F2230/00 , A61F2240/001 , A61F2240/005 , A61L27/34 , A61L27/48 , A61L27/507 , A61L27/56 , A61L2420/04 , A61L2420/08 , A61L2430/20 , Y10T29/49412 , C08L27/18
摘要： A thin, biocompatible, high-strength, composite material is disclosed that is suitable for use in various implanted configurations. The composite material maintains flexibility in high-cycle flexural applications, making it particularly applicable to high-flex implants such as heart pacing lead or heart valve leaflet. The composite material includes at least one porous expanded fluoropolymer layer and an elastomer substantially filling substantially all of the pores of the porous expanded fluoropolymer.
摘要翻译： 公开了一种适用于各种植入构型的薄的，生物相容的，高强度的复合材料。 复合材料在高周期弯曲应用中保持灵活性，使其特别适用于高柔性植入物，如心脏起搏引线或心脏瓣膜小叶。 复合材料包括至少一个多孔膨胀氟聚合物层和基本上填充多孔膨胀氟聚合物的基本上所有孔的弹性体。
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公开(公告)号：US5258040A
公开(公告)日：1993-11-02
申请号：US662184
申请日：1991-02-28
CPC分类号： A61F2/08 , A61L27/16 , Y10S623/909
摘要： The inventive article is a ligament or tendon prosthesis having multiple longitudinally parallel strands of microporous expanded polytetrafluoroethylene, the individual strands having an average porosity greater than 30% in the areas requiring tissue ingrowth. Additionally, strand dimensions and microstructure are selected so that tissue can penetrate throughout. The prosthesis is formed from multiple loops of a single continuous filament. Densified eyelets are formed in the loop for mounting to bone. The strands are twisted 180.degree. or arranged in a loose braid about the prosthesis axis for improved load distribution during bending of the prosthesis.
摘要翻译： 本发明的制品是具有多个纵向平行的微孔膨胀聚四氟乙烯股线的韧带或腱假体，在需要组织向内生长的区域中，各股线的平均孔隙率大于30％。 另外，选择线的尺寸和微结构使得组织可以贯穿整个。 假体由单个连续细丝的多个环形成。 在环中形成密封的孔眼以安装到骨头。 股线扭转180°或围绕假体轴布置在松散的编织物中，以改善假体弯曲期间的负荷分布。
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公开(公告)号：US5584876A
公开(公告)日：1996-12-17
申请号：US235071
申请日：1994-04-29
摘要： The present invention is directed to a sheath for use with vascular prostheses derived from donor blood vessels, particularly mammalian blood vessels. A vascular prosthesis of the present invention employs an external sheath around a donor blood vessel. The sheath prevents access to the donor vessel wall by host cells originating from perigraft tissue. While resistant to host cell ingrowth, the external sheath is permeable to the flux of macromolecules across its thickness. The exclusion of host cells by the external sheath and the bi-directional flow of macromolecules through the external sheath assists in maintaining the original function of the underlying donor vascular tissue of the prosthesis.
摘要翻译： 本发明涉及用于源自供体血管，特别是哺乳动物血管的血管假体的护套。 本发明的血管假体在供体血管周围采用外鞘。 护套防止由源自周围组织的宿主细胞进入供体血管壁。 虽然对宿主细胞向内生长具有抗性，外鞘对其大分子的通量在其厚度上是可渗透的。 通过外部护套排除宿主细胞和通过外部鞘的大分子的双向流动有助于维持假体的潜在供体血管组织的原始功能。
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公开(公告)号：US5197983A
公开(公告)日：1993-03-30
申请号：US747595
申请日：1991-08-20
IPC分类号： A61F2/08
CPC分类号： A61F2/08
摘要： This invention provides for an improved implantable prosthetic device and in particular to a prosthetic ligament or tendon. One process provides for a means by which tensile loads may be transferred from one-load bearing member of the prosthesis to another so that damage at different sites is isolated. Another process provides a means by which the prosthesis is more abrasion resistant.
摘要翻译： 本发明提供了一种改进的可植入假体装置，特别涉及一种假体韧带或腱。 一种方法提供了一种可以将拉伸载荷从假体的单承载构件转移到另一方的装置，使得在不同位置处的损伤被隔离。 另一种方法提供了假体更耐磨的手段。
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公开(公告)号：US4321914A
公开(公告)日：1982-03-30
申请号：US142840
申请日：1980-04-22
CPC分类号： A61M39/0247 , A61M2039/0261
摘要： A percutaneous device to provide a path from the exterior of the epidermal tissue to interior body spaces and structures with a skirt of material with PTFE having an open microstructure for the ingrowth of epidermal and connective tissue.
摘要翻译： 提供从表皮组织的外部到内部空间和结构的经皮装置，其中具有PTFE的材料裙部具有用于表皮和结缔组织向内生长的开放微结构。
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公开(公告)号：US5049155A
公开(公告)日：1991-09-17
申请号：US568625
申请日：1990-08-16
摘要： The inventive article is a ligament or tendon prosthesis having multiple longitudinally parallel strands of microporous expanded polytetrafluoroethylene, the individual strands having an average porosity greater than 30% in the areas requiring tissue ingrowth. Additionally, strand dimensions and microstructure are selected so that tissue can penetrate throughout. The prosthesis is formed from multiple loops of a single continuous filament. Densified eyelets are formed in the loop for mounting to bone. The strands are twisted 180.degree. or arranged in a loose braid about the prothesis axis for improved load distribution during bending of the prosthesis.
摘要翻译： 本发明的制品是具有多个纵向平行的微孔膨胀聚四氟乙烯股线的韧带或腱假体，在需要组织向内生长的区域中，各股线的平均孔隙率大于30％。 另外，选择线的尺寸和微结构使得组织可以贯穿整个。 假体由单个连续细丝的多个环形成。 在环中形成密封的孔眼以安装到骨头。 股线被扭转180°或者围绕假体轴线布置在松散的编织物中，以改善假体弯曲期间的负荷分布。
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