公开(公告)号：US5197983A

公开(公告)日：1993-03-30

申请号：US747595

申请日：1991-08-20

申请人： Andrew B. Berman ,  William C. Bruchman ,  Stanislaw L. Zukowski

发明人： Andrew B. Berman ,  William C. Bruchman ,  Stanislaw L. Zukowski

IPC分类号： A61F2/08

CPC分类号： A61F2/08

摘要： This invention provides for an improved implantable prosthetic device and in particular to a prosthetic ligament or tendon. One process provides for a means by which tensile loads may be transferred from one-load bearing member of the prosthesis to another so that damage at different sites is isolated. Another process provides a means by which the prosthesis is more abrasion resistant.

摘要翻译： 本发明提供了一种改进的可植入假体装置，特别涉及一种假体韧带或腱。 一种方法提供了一种可以将拉伸载荷从假体的单承载构件转移到另一方的装置，使得在不同位置处的损伤被隔离。 另一种方法提供了假体更耐磨的手段。

公开(公告)号：US07641958B2

公开(公告)日：2010-01-05

申请号：US10133653

申请日：2002-04-25

申请人： Andrew B. Berman ,  Thane L. Kranzer ,  Dean R. Wentworth

发明人： Andrew B. Berman ,  Thane L. Kranzer ,  Dean R. Wentworth

IPC分类号： A61F2/04 ,  A61F2/02 ,  B32B5/22

CPC分类号： A61L17/04 ,  A61F2/0063 ,  A61F2/0077 ,  A61F2002/0081 ,  A61F2002/0086 ,  A61F2002/009 ,  A61L27/16 ,  A61L27/50 ,  Y10T428/24355 ,  Y10T428/24372 ,  Y10T428/24405 ,  Y10T428/24479 ,  Y10T428/249979 ,  Y10T428/31544 ,  C08L27/18

摘要： An improved, polymeric surgical membrane, which can be used in a variety of surgical procedures, such as sutured and sutureless duraplasty procedures. For sutureless applications, a textured, discontinuous, outer polymer layer is provided which encourages rapid incorporation and anchoring into surrounding tissue. In cooperation with the discontinuous first layer, a second elastomeric layer provides elasticity and resilience. A third barrier layer is provided to essentially eliminate adhesions and irritation to surrounding tissue. In those applications requiring anchoring sutures, the second elastomeric layer “self-seals” against the sutures, essentially eliminating the leakage of blood, cerebrospinal fluid, or other fluids. In addition, the composite structure of the present invention has a high degree of suture retention strength is polymeric with a high degree of biocompatibility, is thin and very flexible.

摘要翻译： 一种改进的聚合物手术膜，其可用于各种外科手术，例如缝合和无缝合的持续成型手术。 对于无缝线应用，提供纹理不连续的外部聚合物层，其促进快速结合并锚定到周围组织中。 与不连续的第一层协作，第二弹性体层提供弹性和弹性。 提供第三阻挡层以基本上消除对周围组织的粘连和刺激。 在需要锚定缝线的那些应用中，第二弹性层“针对缝合线”自我密封“，基本上消除了血液，脑脊髓液或其它液体的泄漏。 此外，本发明的复合结构具有高度的缝合保持强度，聚合物具有高度的生物相容性，薄且非常灵活。

公开(公告)号：US5899942A

公开(公告)日：1999-05-04

申请号：US79346

申请日：1998-05-15

申请人： Andrew B. Berman

发明人： Andrew B. Berman

IPC分类号： A61B17/06 ,  A61F2/00 ,  A61F2/30 ,  A61F2/32 ,  A61F2/34 ,  A61F2/36 ,  A61F2/46 ,  A61L27/16

CPC分类号： A61F2/30742 ,  A61L27/16 ,  A61B17/06166 ,  A61F2/32 ,  A61F2/34 ,  A61F2/367 ,  A61F2002/30013 ,  A61F2002/30113 ,  A61F2002/30115 ,  A61F2002/30125 ,  A61F2002/30176 ,  A61F2002/30217 ,  A61F2002/30322 ,  A61F2002/30332 ,  A61F2002/30448 ,  A61F2002/30461 ,  A61F2002/30462 ,  A61F2002/30594 ,  A61F2002/30596 ,  A61F2002/30604 ,  A61F2002/30682 ,  A61F2002/30772 ,  A61F2002/3625 ,  A61F2002/3631 ,  A61F2002/365 ,  A61F2002/4631 ,  A61F2220/0033 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2230/0006 ,  A61F2230/0008 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2250/0024 ,  A61F2250/0026

摘要： The disclosure relates to a tissue and debris barrier for use in association with implanted joint replacement devices. The barrier comprises a biocompatible membrane that is impermeable to debris. The membrane defines an aperture which is positioned about a component of the joint replacement prosthesis. The periphery of the membrane may be mechanically attached by suturing to adjacent tissue or may be provided with areas of selected porosity to promote tissue adherence. The barrier permits full motion of the replacement joint while preventing or impeding tissue and debris from migrating to and from bone implant interfaces.

摘要翻译： 本公开涉及与植入关节置换装置相关联使用的组织和碎片屏障。 屏障包括不透气的生物相容膜。 膜限定了围绕关节置换假体的部件定位的孔。 膜的周边可以通过缝合到相邻组织而机械附着，或者可以设置有选择的孔隙率的区域以促进组织粘附。 屏障允许替换关节的全运动，同时防止或阻止组织和碎屑迁移到骨植入物界面和从骨植入物界面迁移。

公开(公告)号：US20100106258A1

公开(公告)日：2010-04-29

申请号：US12624877

申请日：2009-11-24

申请人： Andrew B. Berman ,  Thane L. Kranzler ,  Dean R. Wentworth

发明人： Andrew B. Berman ,  Thane L. Kranzler ,  Dean R. Wentworth

IPC分类号： A61F2/02

CPC分类号： A61L17/04 ,  A61F2/0063 ,  A61F2/0077 ,  A61F2002/0081 ,  A61F2002/0086 ,  A61F2002/009 ,  A61L27/16 ,  A61L27/50 ,  Y10T428/24355 ,  Y10T428/24372 ,  Y10T428/24405 ,  Y10T428/24479 ,  Y10T428/249979 ,  Y10T428/31544 ,  C08L27/18

摘要： An improved, polymeric surgical membrane, which can be used in a variety of surgical procedures, such as sutured and sutureless duraplasty procedures. For sutureless applications, a textured, discontinuous, outer polymer layer is provided which encourages rapid incorporation and anchoring into surrounding tissue. In cooperation with the discontinuous first layer, a second elastomeric layer provides elasticity and resilience. A third barrier layer is provided to essentially eliminate adhesions and irritation to surrounding tissue. In those applications requiring anchoring sutures, the second elastomeric layer “self-seals” against the sutures, essentially eliminating the leakage of blood, cerebrospinal fluid, or other fluids. In addition, the composite structure of the present invention has a high degree of suture retention strength is polymeric with a high degree of biocompatibility, is thin and very flexible.

摘要翻译： 一种改进的聚合物手术膜，其可用于各种外科手术，例如缝合和无缝合的持续成型手术。 对于无缝线应用，提供纹理不连续的外部聚合物层，其促进快速结合并锚定到周围组织中。 与不连续的第一层协作，第二弹性体层提供弹性和弹性。 提供第三阻挡层以基本上消除对周围组织的粘连和刺激。 在需要锚定缝线的那些应用中，第二弹性层“针对缝合线”自我密封“，基本上消除了血液，脑脊髓液或其它液体的泄漏。 此外，本发明的复合结构具有高度的缝合保持强度，聚合物具有高度的生物相容性，薄且非常灵活。

公开(公告)号：US07985263B2

公开(公告)日：2011-07-26

申请号：US12624877

申请日：2009-11-24

申请人： Andrew B. Berman ,  Thane L. Kranzer ,  Dean R. Wentworth

发明人： Andrew B. Berman ,  Thane L. Kranzer ,  Dean R. Wentworth

IPC分类号： A61F2/04 ,  A61F2/02 ,  B32B5/22

CPC分类号： A61L17/04 ,  A61F2/0063 ,  A61F2/0077 ,  A61F2002/0081 ,  A61F2002/0086 ,  A61F2002/009 ,  A61L27/16 ,  A61L27/50 ,  Y10T428/24355 ,  Y10T428/24372 ,  Y10T428/24405 ,  Y10T428/24479 ,  Y10T428/249979 ,  Y10T428/31544 ,  C08L27/18

摘要： An improved, polymeric surgical membrane, which can be used in a variety of surgical procedures, such as sutured and sutureless duraplasty procedures. For sutureless applications, a textured, discontinuous, outer polymer layer is provided which encourages rapid incorporation and anchoring into surrounding tissue. In cooperation with the discontinuous first layer, a second elastomeric layer provides elasticity and resilience. A third barrier layer is provided to essentially eliminate adhesions and irritation to surrounding tissue. In those applications requiring anchoring sutures, the second elastomeric layer “self-seals” against the sutures, essentially eliminating the leakage of blood, cerebrospinal fluid, or other fluids. In addition, the composite structure of the present invention has a high degree of suture retention strength is polymeric with a high degree of biocompatibility, is thin and very flexible.

摘要翻译： 一种改进的聚合物手术膜，其可用于各种外科手术，例如缝合和无缝合的持续成型手术。 对于无缝线应用，提供纹理不连续的外部聚合物层，其促进快速结合并锚定到周围组织中。 与不连续的第一层协作，第二弹性体层提供弹性和弹性。 提供第三阻挡层以基本上消除对周围组织的粘连和刺激。 在需要锚定缝线的那些应用中，第二弹性层“针对缝合线”自我密封“，基本上消除了血液，脑脊髓液或其它液体的泄漏。 此外，本发明的复合结构具有高度的缝合保持强度，聚合物具有高度的生物相容性，薄且非常灵活。

公开(公告)号：US6132470A

公开(公告)日：2000-10-17

申请号：US801402

申请日：1997-02-20

申请人： Andrew B. Berman

发明人： Andrew B. Berman

IPC分类号： A61B17/06 ,  A61F2/00 ,  A61F2/30 ,  A61F2/32 ,  A61F2/34 ,  A61F2/36 ,  A61F2/46 ,  A61L27/16 ,  A61L31/04

CPC分类号： A61L27/16 ,  A61F2/30742 ,  A61L31/048 ,  A61B17/06166 ,  A61F2/32 ,  A61F2/34 ,  A61F2/367 ,  A61F2002/30011 ,  A61F2002/30013 ,  A61F2002/30113 ,  A61F2002/30115 ,  A61F2002/30125 ,  A61F2002/30176 ,  A61F2002/30217 ,  A61F2002/30322 ,  A61F2002/30332 ,  A61F2002/30448 ,  A61F2002/30461 ,  A61F2002/30462 ,  A61F2002/30594 ,  A61F2002/30596 ,  A61F2002/30604 ,  A61F2002/30682 ,  A61F2002/30772 ,  A61F2002/30971 ,  A61F2002/3625 ,  A61F2002/3631 ,  A61F2002/365 ,  A61F2002/4631 ,  A61F2220/0033 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2230/0006 ,  A61F2230/0008 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2240/001 ,  A61F2250/0023 ,  A61F2250/0024 ,  A61F2250/0026 ,  Y10S623/926

摘要： The disclosure relates to a tissue and debris barrier for use in association with implanted joint replacement devices. The barrier comprises a biocompatible membrane that is impermeable to debris. The membrane defines an aperture which is positioned about a component of the joint replacement prosthesis. The periphery of the membrane may be mechanically attached by suturing to adjacent tissue. The barrier permits full motion of the replacement joint while preventing or impeding tissue and debris from migrating to and from bone implant interfaces. The preferred barrier material is porous expanded PTFE with one side having a microstructure that promotes tissue attachment and the opposing side having a microstructure that allows highly efficient filtration of fine particulate debris. The barrier may be a single layer material or may be a composite construction in which two or more layers are bonded together.

摘要翻译： 本公开涉及与植入关节置换装置相关联使用的组织和碎片屏障。 屏障包括不透气的生物相容膜。 膜限定了围绕关节置换假体的部件定位的孔。 膜的周边可以通过缝合机械连接到相邻的组织。 屏障允许替换关节的全运动，同时防止或阻止组织和碎屑迁移到骨植入物界面和从骨植入物界面迁移。 优选的阻隔材料是多孔膨体PTFE，其一侧具有促进组织附着的微结构，相对侧具有允许高效过滤细颗粒碎片的微结构。 阻挡层可以是单层材料，或者可以是其中两层或更多层结合在一起的复合结构。

公开(公告)号：US6017366A

公开(公告)日：2000-01-25

申请号：US844486

申请日：1997-04-18

申请人： Andrew B. Berman

发明人： Andrew B. Berman

IPC分类号： A61L27/00 ,  A61B17/56 ,  A61F2/00 ,  A61F2/02 ,  A61F2/08 ,  A61F2/30 ,  A61F2/42 ,  A61L27/58

CPC分类号： A61B17/562 ,  A61F2/4261 ,  A61L27/58 ,  A61F2/08 ,  A61F2002/30034 ,  A61F2002/30062 ,  A61F2002/30293 ,  A61F2002/30299 ,  A61F2002/30301 ,  A61F2002/30563 ,  A61F2002/30754 ,  A61F2002/30878 ,  A61F2002/4248 ,  A61F2002/4258 ,  A61F2002/4276 ,  A61F2210/0004 ,  A61F2230/0091 ,  A61F2230/0093 ,  A61F2230/0095 ,  A61F2250/0031

摘要： A resorbable implant for interposition arthroplasty which is intended to fill a void between two adjacent bone ends, providing a cushion between the bone ends to prevent impingement of the bone ends while providing time for tissue to infiltrate into the space occupied by the implant. It has a protracted resorption time of preferably at least three months to allow time for the proliferation of load-bearing host fibrous tissue in place of the resorbed implant material. The implant preferably is porous with a pore size of greater than about 80 microns in order to enhance infiltration of fibrous tissue. The implant has a modulus in the range of 0.8 to 20 MPa which is soft enough to allow it to conform to surface irregularities of the adjacent bone surfaces while being hard enough to maintain a desired separation between those bones while tissue infiltration replaces the resorbable implant material. The implant may be preformed to the desired shape or alternatively may be formable by the surgeon by methods such as carving with a scalpel. A preferred application for the implant is as a trapezium bone replacement.

摘要翻译： 用于插入关节成形术的可再吸收植入物，其旨在填充两个相邻骨端之间的空隙，在骨端之间提供衬垫，以防止骨端部的撞击，同时为组织浸入到由植入物占据的空间中提供时间。 它具有优选至少三个月的延长吸收时间，以允许承载宿主纤维组织的增殖代替吸收的植入材料的时间。 为了增强纤维组织的浸润，植入物优选是多孔的孔径大于约80微米。 植入物具有在0.8至20MPa的范围内的模量，其足够柔软以使其符合相邻骨表面的表面不规则性，同时足够坚硬以在这些骨骼之间保持期望的分离，同时组织浸润取代可再吸收的植入材料 。 植入物可以预成形为期望的形状，或者可以由外科医生通过诸如用手术刀雕刻的方法形成。 植入物的优选应用是梯形骨置换。