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公开(公告)号：US20050015112A1
公开(公告)日：2005-01-20
申请号：US10713386
申请日：2003-11-13
申请人： William Cohn , Gregory Lambrecht , John Liddicoat , Robert Moore , Richard Streeter , Todd Davenport
发明人： William Cohn , Gregory Lambrecht , John Liddicoat , Robert Moore , Richard Streeter , Todd Davenport
CPC分类号： A61F2/2412 , A61F2/2427 , A61F2220/0016 , A61F2250/0059
摘要： Devices and methods for performing intravascular procedures without cardiac bypass include embodiments of temporary filter devices, temporary valves, and prosthetic valves. The temporary filter devices have a cannula which provides access for surgical tools for effecting repair of cardiac valves. The cannula may have filters which prevent embolitic material from entering the coronary arteries and aorta. The valve devices may also have a cannula for insertion of the valve into the aorta. The valve devices expand in the aorta to occupy the entire flow path of the vessel and operate to prevent blood flow and to permit flow through the valve. The prosthetic valves include valve fixation devices which secure the prosthetic valve to the wall of the vessel. The prosthetic valves are introduced into the vascular system in a compressed state, advanced to the site of implantation, and expanded and secured to the vessel wall.
摘要翻译： 不用心脏旁路进行血管内手术的装置和方法包括临时过滤装置，临时阀和人工瓣膜的实施例。 临时过滤装置具有套管，该套管为进行心脏瓣膜修复的外科手术工具提供通路。 套管可以具有防止栓塞材料进入冠状动脉和主动脉的过滤器。 瓣膜装置还可以具有用于将瓣膜插入主动脉的插管。 瓣膜装置在主动脉中膨胀以占据血管的整个流动路径，并且操作以防止血液流动并允许流过瓣膜。 假体瓣膜包括固定假体瓣膜至血管壁的瓣膜固定装置。 假体瓣膜以压缩状态引入血管系统中，前进到植入部位，并且扩张并固定到血管壁。
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公开(公告)号：US20050010246A1
公开(公告)日：2005-01-13
申请号：US10772782
申请日：2004-02-05
CPC分类号： A61F2/013 , A61F2/01 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/008
摘要： Apparatus for filtering and entrapping debris in the vascular system of a patient, the apparatus including a filter to allow blood to flow therethrough and to restrict passage of debris, wherein the filter captures debris carried in a first direction of blood flow. The apparatus further includes an entrapment mechanism which allows passage of debris and blood therethrough, in the first direction of blood flow and prevents debris passage in a second direction. The entrapment mechanism and filter allow blood and debris therethrough in the first direction of blood flow. The entrapment mechanism prevents debris flow in the second direction of blood flow. A method for filtering and entrapping debris in the vascular system includes inserting the apparatus into the vascular system, allowing blood and debris carried therein to flow through the entrapment mechanism, and removing the apparatus and accumulated debris from the vascular system.
摘要翻译： 用于过滤和捕获患者血管系统中的碎屑的装置，所述装置包括允许血液流过其中并且限制碎屑通过的过滤器，其中所述过滤器捕获沿第一血流方向携带的碎屑。 该装置还包括捕获机构，其允许碎屑和血液沿第一血流方向通过，并且防止碎片在第二方向上通过。 捕获机构和过滤器允许在第一血流方向上的血液和碎屑通过其中。 捕获机制防止泥石流在第二个血流方向。 用于过滤和捕获血管系统中的碎屑的方法包括将装置插入血管系统中，允许其中携带的血液和碎屑流过夹带机构，以及从血管系统移除装置并累积碎屑。
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公开(公告)号：US20050055088A1
公开(公告)日：2005-03-10
申请号：US10895272
申请日：2004-07-20
申请人： John Liddicoat , Gregory Lambrecht , Todd Davenport , William Cohn , Steven Woolfson , Daniel Taylor
发明人： John Liddicoat , Gregory Lambrecht , Todd Davenport , William Cohn , Steven Woolfson , Daniel Taylor
CPC分类号： A61F2/2427 , Y10S623/902
摘要： The present invention comprises a method for deploying an aortic valve prosthesis. This valve prosthesis may include any of the known aortic valves including, but not limited to, stented and unstented bioprosthetic valves, stented mechanical valves, and expandable or self-expanding valves, whether biological or artificial. The method involves the steps of: making a first opening leading to the left atrium; passing a valve prosthesis through the opening and into a cardiac chamber of the left side of the heart using a first manipulation instrument; making a second opening in the arterial system and advancing one end of a second manipulation instrument through the arterial opening and into the aforementioned cardiac chamber; securing the second manipulation instrument to the valve prosthesis; and using the second manipulation instrument to retract at least some portion of the valve prosthesis out of the aforementioned cardiac chamber.
摘要翻译： 本发明包括用于展开主动脉瓣假体的方法。 该瓣膜假体可以包括任何已知的主动脉瓣，包括但不限于支架化和不连续的生物假体瓣膜，支架式机械瓣膜，以及可膨胀或自膨胀阀，无论是生物还是人造的。 该方法包括以下步骤：使通向左心房的第一开口; 使用第一操纵仪器使阀门假体穿过开口进入心脏左侧的心室; 在所述动脉系统中形成第二开口，并使第二操纵器具的一端通过所述动脉开口并进入所述心室; 将第二操纵仪器固定到瓣膜假体上; 以及使用所述第二操纵器械使所述瓣膜假体的至少一部分从所述心室收回。
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公开(公告)号：US20070213814A1
公开(公告)日：2007-09-13
申请号：US11714710
申请日：2007-03-06
申请人： John Liddicoat , Daniel Taylor , Richard Streeter , Steven Woolfson , William Cohn , Todd Davenport
发明人： John Liddicoat , Daniel Taylor , Richard Streeter , Steven Woolfson , William Cohn , Todd Davenport
IPC分类号： A61F2/24
CPC分类号： A61F2/2451 , A61F2/2466 , Y10S623/903 , Y10S623/904
摘要： A method and apparatus for reducing mitral regurgitation. The apparatus is inserted into the coronary sinus of a patient in the vicinity of the posterior leaflet of the mitral valve, the apparatus being adapted to straighten the natural curvature of at least a portion of the coronary sinus in the vicinity of the posterior leaflet of the mitral valve, whereby to move the posterior annulus anteriorly and thereby improve leaflet coaptation and reduce mitral regurgitation.
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公开(公告)号：US20080103590A1
公开(公告)日：2008-05-01
申请号：US11818991
申请日：2007-06-15
申请人： Daniel Taylor , William Cohn , John Liddicoat , Steven Woolfson , Todd Davenport , Richard Streeter , Thomas Kordis , Jonathan Rourke
发明人： Daniel Taylor , William Cohn , John Liddicoat , Steven Woolfson , Todd Davenport , Richard Streeter , Thomas Kordis , Jonathan Rourke
CPC分类号： A61F2/2451 , A61B17/3468 , A61B17/3478 , A61B2017/00247 , A61B2018/00392 , A61F2250/0007 , A61F2250/0063 , Y10S623/904
摘要： A method and device for reducing mitral regurgitation. An elongated body is positioned in a coronary sinus of a patient in a vicinity of a heart mitral valve posterior leaflet. The body is adapted to straighten a natural curvature of at least a portion of the coronary sinus in the vicinity of the posterior leaflet to move a posterior annulus anteriorly, which in turn moves the posterior leaflet anteriorly, thereby to improve leaflet coaptation.
摘要翻译： 一种减少二尖瓣反流的方法和装置。 细长的身体位于心脏二尖瓣后叶附近的患者的冠状窦内。 身体适于矫正在后小叶附近的冠状窦的至少一部分的自然曲率，以向前移动后环，这又使前叶向前移动，从而改善小叶接合。
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公开(公告)号：US20060229717A1
公开(公告)日：2006-10-12
申请号：US11371642
申请日：2006-03-09
CPC分类号： A61F2/2451 , A61B17/3468 , A61B17/3478 , A61B2017/00247 , A61B2018/00392 , A61F2250/0007 , A61F2250/0063 , Y10S623/904
摘要： A method for reducing mitral regurgitation includes deploying deforming matter into a selected one of (i) a mitral valve annulus adjacent a posterior leaflet, and (ii) tissue adjacent the mitral valve annulus and proximate the posterior leaflet, to cause conformational change in the mitral valve annulus to increase mitral valve leaflet coaptation.
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公开(公告)号：US20050049679A1
公开(公告)日：2005-03-03
申请号：US10641975
申请日：2003-08-15
申请人： Daniel Taylor , John Liddicoat , Richard Streeter , Steven Woolfson , William Cohn , Todd Davenport , Thomas Kordis
发明人： Daniel Taylor , John Liddicoat , Richard Streeter , Steven Woolfson , William Cohn , Todd Davenport , Thomas Kordis
CPC分类号： A61F2/2451
摘要： A method and apparatus for reducing mitral regurgitation. The apparatus is inserted into the coronary sinus of a patient in the vicinity of the posterior leaflet of the mitral valve, the apparatus being adapted to straighten the natural curvature of at least a portion of the coronary sinus in the vicinity of the posterior leaflet of the mitral valve, whereby to move the posterior annulus anteriorly and thereby improve leaflet coaptation and reduce mitral regurgitation.
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公开(公告)号：US20050261669A1
公开(公告)日：2005-11-24
申请号：US11115087
申请日：2005-04-26
申请人： Richard Streeter , John Liddicoat , Todd Davenport
发明人： Richard Streeter , John Liddicoat , Todd Davenport
CPC分类号： A61N1/36114 , A61B17/3417 , A61B2017/00243 , A61B2017/00969 , A61B2017/0243 , A61B2017/3445 , A61B2017/3449 , A61N1/056 , A61N1/362 , A61N1/385 , A61N1/3962
摘要： Apparatus is disclosed for providing access to a functioning vascular system of a patient, the apparatus comprising: a main body having sidewalls defining an interior region and an exterior region, a bottom end and a top end; a base being formed at the bottom end of the main body, securing means being configured on the base so as to allow attachment and formation of a seal between the base and the functioning vascular system of the patient, and the base being configurable to provide a passageway from the interior region of the main body to the functioning vascular system of the patient; and a cover being formed at the top end of the main body, wherein the cover provides a barrier between the interior region and the exterior region at the top end of the main body.
摘要翻译： 公开了用于提供对患者的功能性血管系统的访问的装置，该装置包括：主体，其具有限定内部区域和外部区域，底部端部和顶端的侧壁; 基部形成在主体的底端，固定装置构造在基部上，以便允许在基部和患者的功能性血管系统之间的密封的附接和形成，并且基座可配置成提供 从主体的内部区域到患者的功能性血管系统的通道; 以及盖，其形成在所述主体的顶端，其中所述盖在所述主体的顶端处在所述内部区域与所述外部区域之间提供阻挡层。
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9.发明授权公开(公告)号：US08142412B2
公开(公告)日：2012-03-27
申请号：US12008130
申请日：2008-01-09
IPC分类号： A61M31/00
CPC分类号： A61L27/56 , A61L29/146 , A61L31/146
摘要： A system comprising: a hollow tube having a distal end, a proximal end, and a lumen extending between the distal end and the proximal end; at least a portion of the tube comprising a porous membrane; and a gas-rich perfluorocarbon solution incorporated in the porous membrane; wherein the porous membrane has a porosity in the range of 0.001-200 microns, in order that: (i) the gas-rich perfluorocarbon solution is effectively incorporated into the porous membrane; and (ii) when the porous membrane is positioned in blood, the gas-rich perfluorocarbon solution elutes out of the porous membrane, in aggregations small enough to prevent the creation of embolisms in the blood, with the elution of the gas-rich perfluorocarbon solution into the blood varying between minutes and several hours, depending on the temperature and the hemodynamics of the blood.
摘要翻译： 一种系统，包括：中空管，其具有远端，近端和在远端和近端之间延伸的内腔; 所述管的至少一部分包括多孔膜; 和掺入多孔膜中的富含气体的全氟化碳溶液; 其中所述多孔膜的孔隙率在0.001-200微米的范围内，以便：（i）富气体全氟化碳溶液有效地并入多孔膜中; 和（ii）当多孔膜位于血液中时，富含气体的全氟化碳溶液以足够小的聚集体从多孔膜中洗脱出来，以防止在血液中产生栓塞，同时溶解富含气体的全氟化碳溶液 根据血液的温度和血液动力学，血液在几分钟到几个小时之间变化。
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10.发明申请公开(公告)号：US20080294086A1
公开(公告)日：2008-11-27
申请号：US12008130
申请日：2008-01-09
CPC分类号： A61L27/56 , A61L29/146 , A61L31/146
摘要： A system comprising: a hollow tube having a distal end, a proximal end, and a lumen extending between the distal end and the proximal end; at least a portion of the tube comprising a porous membrane; and a gas-rich perfluorocarbon solution incorporated in the porous membrane; wherein the porous membrane has a porosity in the range of 0.001-200 microns, in order that: (i) the gas-rich perfluorocarbon solution is effectively incorporated into the porous membrane; and (ii) when the porous membrane is positioned in blood, the gas-rich perfluorocarbon solution elutes out of the porous membrane, in aggregations small enough to prevent the creation of embolisms in the blood, with the elution of the gas-rich perfluorocarbon solution into the blood varying between minutes and several hours, depending on the temperature and the hemodynamics of the blood.
摘要翻译： 一种系统，包括：中空管，其具有远端，近端和在远端和近端之间延伸的内腔; 所述管的至少一部分包括多孔膜; 和掺入多孔膜中的富含气体的全氟化碳溶液; 其中所述多孔膜的孔隙率在0.001-200微米的范围内，以便：（i）富气体全氟化碳溶液有效地并入多孔膜中; 和（ii）当多孔膜位于血液中时，富含气体的全氟化碳溶液以足够小的聚集体从多孔膜中洗脱出来，以防止在血液中产生栓塞，同时溶解富含气体的全氟化碳溶液 根据血液的温度和血液动力学，血液在几分钟到几个小时之间变化。
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