公开(公告)号：US07200434B2

公开(公告)日：2007-04-03

申请号：US11089798

申请日：2005-03-25

申请人： William J. Havel ,  Paul J. Degroot ,  Thomas W. Sinner ,  Kevin Kuehn ,  Gary Kemmetmueller ,  Warren W. Wold

发明人： William J. Havel ,  Paul J. Degroot ,  Thomas W. Sinner ,  Kevin Kuehn ,  Gary Kemmetmueller ,  Warren W. Wold

IPC分类号： A61N1/39

CPC分类号： A61N1/3906 ,  A61N1/3912 ,  A61N1/3937

摘要： The present invention outlines structures and methods for delivering a controllable amount of energy to a patient by automatically compensating for the load impedance detected by an implantable-cardioverter defibrillator (ICD). The invention employs high speed, switching power converter technology for the efficient generation of high energy, arbitrarywaveforms. Unlike a linear amplifier, switching power converters deliver high-energy waveforms with an efficiency that is independent of the size and amplitude of the desired waveform. An ICD that uses a switching power converter to deliver the desired energy to the patient stores the energy to be delivered in a storage capacitor. The converter then transforms this energy into an arbitrarily shaped output voltage-controlled or current-controlled waveform by switching the storage capacitor in and out of the output circuit at a high rate of speed. Preferably, the waveform comprises a ramp-type waveform.

摘要翻译： 本发明概述了通过自动补偿由可植入式心律转复除颤器（ICD）检测的负载阻抗来向患者传送可控量的能量的结构和方法。 本发明采用高速，开关电源转换器技术，有效地生成高能量，任意波形。 与线性放大器不同，开关电源转换器提供高能量波形，效率与所需波形的大小和幅度无关。 使用开关功率转换器将期望的能量递送到患者的ICD存储要在存储电容器中传递的能量。 然后，转换器通过以高速率切换存储电容器输入和输出输出电路，将该能量转换成任意形状的输出电压控制或电流控制波形。 优选地，波形包括斜坡型波形。

公开(公告)号：US07151963B2

公开(公告)日：2006-12-19

申请号：US10308832

申请日：2002-12-03

申请人： William J. Havel ,  Paul J. DeGroot ,  Thomas W. Sinner ,  Kevin Kuehn ,  Gary Kemmetmueller ,  Warren W. Wold

发明人： William J. Havel ,  Paul J. DeGroot ,  Thomas W. Sinner ,  Kevin Kuehn ,  Gary Kemmetmueller ,  Warren W. Wold

IPC分类号： A61N1/39

CPC分类号： A61N1/3906 ,  A61N1/3912 ,  A61N1/3937

摘要： The present invention outlines structures and methods for delivering a controllable amount of energy to a patient by automatically compensating for the load impedance detected by an implantable-cardioverter defibrillator (ICD). The invention employs high speed, switching power converter technology for the efficient generation of high energy, arbitrary waveforms. Unlike a linear amplifier, switching power converters deliver high-energy waveforms with an efficiency that is independent of the size and amplitude of the desired waveform. An ICD that uses a switching power converter to deliver the desired energy to the patient stores the energy to be delivered in a storage capacitor. The converter then transforms this energy into an arbitrarily shaped output voltage-controlled or current-controlled waveform by switching the storage capacitor in and out of the output circuit at a high rate of speed. Preferably, the waveform comprises a ramp-type waveform.

公开(公告)号：US20050228453A1

公开(公告)日：2005-10-13

申请号：US11089798

申请日：2005-03-25

申请人： William Havel ,  Paul Degroot ,  Thomas Sinner ,  Kevin Kuehn ,  Gary Kemmetmueller ,  Warren Wold

发明人： William Havel ,  Paul Degroot ,  Thomas Sinner ,  Kevin Kuehn ,  Gary Kemmetmueller ,  Warren Wold

IPC分类号： A61B5/05 ,  A61N1/04 ,  A61N1/08 ,  A61N1/39

CPC分类号： A61N1/3906 ,  A61N1/3912 ,  A61N1/3937

摘要： The present invention outlines structures and methods for delivering a controllable amount of energy to a patient by automatically compensating for the load impedance detected by an implantable-cardioverter defibrillator (ICD). The invention employs high speed, switching power converter technology for the efficient generation of high energy, arbitrarywaveforms. Unlike a linear amplifier, switching power converters deliver high-energy waveforms with an efficiency that is independent of the size and amplitude of the desired waveform. An ICD that uses a switching power converter to deliver the desired energy to the patient stores the energy to be delivered in a storage capacitor. The converter then transforms this energy into an arbitrarily shaped output voltage-controlled or current-controlled waveform by switching the storage capacitor in and out of the output circuit at a high rate of speed. Preferably, the waveform comprises a ramp-type waveform.

摘要翻译： 本发明概述了通过自动补偿由可植入式心律转复除颤器（ICD）检测的负载阻抗来向患者传送可控量的能量的结构和方法。 本发明采用高速，开关电源转换器技术，有效地生成高能量，任意波形。 与线性放大器不同，开关电源转换器提供高能量波形，效率与所需波形的大小和幅度无关。 使用开关功率转换器将期望的能量递送到患者的ICD存储要在存储电容器中传递的能量。 然后，转换器通过以高速率切换存储电容器输入和输出输出电路，将该能量转换成任意形状的输出电压控制或电流控制波形。 优选地，波形包括斜坡型波形。

公开(公告)号：US08428717B2

公开(公告)日：2013-04-23

申请号：US10684759

申请日：2003-10-14

申请人： Li Wang ,  Yong K. Cho ,  Kevin Kuehn ,  Glenn C. Zillmer ,  Nirav V. Sheth

发明人： Li Wang ,  Yong K. Cho ,  Kevin Kuehn ,  Glenn C. Zillmer ,  Nirav V. Sheth

IPC分类号： A61N1/365

CPC分类号： A61B5/4869 ,  A61B5/0537 ,  A61B5/0538 ,  A61B5/7203 ,  A61B5/7285 ,  A61N1/3627 ,  A61N1/36521 ,  A61N1/3962

摘要： A fluid status monitoring system for use in implantable cardiac stimulation or monitoring devices is provided for monitoring changes in thoracic fluid content. A fluid status monitor includes excitation pulse generating and control circuitry, and voltage and current measurement and control circuitry for performing a series of cardiac-gated, intra-thoracic impedance measurements. The cardiac-gated measurements are filtered or time-averaged to provide a fluid status impedance value, with respiratory noise removed. Based on comparative analysis of the fluid status impedance value, a clinically relevant trend in fluid status may be tentatively diagnosed and a fluid status response provided. Cross-check intra-thoracic impedance measurements performed using the same or a different excitation pathway and a different measurement pathway than the primary intra-thoracic impedance measurement configuration may be used to verify a tentative diagnosis.

摘要翻译： 提供用于植入式心脏刺激或监测装置的流体状态监测系统，用于监测胸腔液含量的变化。 流体状态监测器包括激励脉冲发生和控制电路以及用于执行一系列心脏门控胸腔内阻抗测量的电压和电流测量和控制电路。 心脏门控测量被过滤或时间平均以提供流体状态阻抗值，消除呼吸噪声。 基于流体状态阻抗值的比较分析，可以暂时诊断流体状态的临床相关趋势，并提供流体状态响应。 使用与主要的胸内阻抗测量配置相同或不同的激发途径和不同的测量路径进行的交叉检查胸内阻抗测量可用于验证临时诊断。

公开(公告)号：US20050080460A1

公开(公告)日：2005-04-14

申请号：US10684759

申请日：2003-10-14

申请人： Li Wang ,  Yong Cho ,  Kevin Kuehn ,  Glenn Zillmer ,  Nirav Sheth

发明人： Li Wang ,  Yong Cho ,  Kevin Kuehn ,  Glenn Zillmer ,  Nirav Sheth

IPC分类号： A61B5/053 ,  A61N1/362 ,  A61N1/365 ,  A61N1/39

CPC分类号： A61B5/4869 ,  A61B5/0537 ,  A61B5/0538 ,  A61B5/7203 ,  A61B5/7285 ,  A61N1/3627 ,  A61N1/36521 ,  A61N1/3962

摘要： A fluid status monitoring system for use in implantable cardiac stimulation or monitoring devices is provided for monitoring changes in thoracic fluid content. A fluid status monitor includes excitation pulse generating and control circuitry, and voltage and current measurement and control circuitry for performing a series of cardiac-gated, intra-thoracic impedance measurements. The cardiac-gated measurements are filtered or time-averaged to provide a fluid status impedance value, with respiratory noise removed. Based on comparative analysis of the fluid status impedance value, a clinically relevant trend in fluid status may be tentatively diagnosed and a fluid status response provided. Cross-check intra-thoracic impedance measurements performed using the same or a different excitation pathway and a different measurement pathway than the primary intra-thoracic impedance measurement configuration may be used to verify a tentative diagnosis.

摘要翻译： 提供用于植入式心脏刺激或监测装置的流体状态监测系统，用于监测胸腔液含量的变化。 流体状态监测器包括激励脉冲发生和控制电路以及用于执行一系列心脏门控胸腔内阻抗测量的电压和电流测量和控制电路。 心脏门控测量被过滤或时间平均以提供流体状态阻抗值，消除呼吸噪声。 基于流体状态阻抗值的比较分析，可以暂时诊断流体状态的临床相关趋势，并提供流体状态响应。 使用与主要的胸内阻抗测量配置相同或不同的激发途径和不同的测量路径进行的交叉检查胸内阻抗测量可用于验证临时诊断。

公开(公告)号：US20070179544A1

公开(公告)日：2007-08-02

申请号：US11343897

申请日：2006-01-31

申请人： Kevin Kuehn

发明人： Kevin Kuehn

IPC分类号： A61N1/00

CPC分类号： A61B5/053 ,  A61B5/0538 ,  A61N1/36521 ,  A61N1/3702

摘要： An implantable medical device (IMD) provides quadripolar transthoracic impedance measurement capability by forming at least one of the two electrodes associated with the canister of the device on a lead proximate the canister.

摘要翻译： 可植入医疗装置（IMD）通过在靠近罐的导线上形成与装置的罐相关联的两个电极中的至少一个来提供四极经胸阻抗测量能力。