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公开(公告)号：US08796405B2
公开(公告)日：2014-08-05
申请号：US13738303
申请日：2013-01-10
Applicant: Wisconsin Alumni Research Foundation
IPC: C08F118/04 , C08F120/70 , C08F120/34 , C08F120/36 , C08F126/02 , C08F126/06
CPC classification number: C08F26/06 , C08F18/04 , C08F18/22 , C08F22/26 , C08F26/02 , C08F216/1458 , C08F218/04 , C08F218/08 , C08F218/10 , C08F226/02 , C08F226/06
Abstract: Described herein are the synthesis and polymerization of a series of N-Boc-protected amino acid vinyl ester (BAAVE) monomers. Homopolymers and heteropolymers containing the monomers are described, particularly heteropolymers with vinyl ester monomers such as vinyl acetate. Deprotection can be used to produce hydrophilic and hydrophobic polymers that are particular useful in biological applications such as cellular delivery of biological materials.
Abstract translation: 本文描述了一系列N-Boc-保护的氨基酸乙烯基酯（BAAVE）单体的合成和聚合。 描述含有单体的均聚物和杂聚物，特别是与乙烯基酯单体如乙酸乙烯酯的异聚物。 脱保护可用于生产特别可用于生物应用的亲水和疏水聚合物，例如生物材料的细胞递送。
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公开(公告)号：US20140296462A1
公开(公告)日：2014-10-02
申请号：US14305039
申请日：2014-06-16
Applicant: Wisconsin Alumni Research Foundation
CPC classification number: C08F26/06 , C08F18/04 , C08F18/22 , C08F22/26 , C08F26/02 , C08F216/1458 , C08F218/04 , C08F218/08 , C08F218/10 , C08F226/02 , C08F226/06
Abstract: Described herein are the synthesis and polymerization of a series of N-Boc-protected amino acid vinyl ester (BAAVE) monomers. Homopolymers and heteropolymers containing the monomers are described, particularly heteropolymers with vinyl ester monomers such as vinyl acetate. Deprotection can be used to produce hydrophilic and hydrophobic polymers that are particular useful in biological applications such as cellular delivery of biological materials.
Abstract translation: 本文描述了一系列N-Boc-保护的氨基酸乙烯基酯（BAAVE）单体的合成和聚合。 描述含有单体的均聚物和杂聚物，特别是与乙烯基酯单体如乙酸乙烯酯的异聚物。 脱保护可用于生产特别可用于生物应用的亲水和疏水聚合物，例如生物材料的细胞递送。
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公开(公告)号：US09688789B2
公开(公告)日：2017-06-27
申请号：US14305039
申请日：2014-06-16
Applicant: Wisconsin Alumni Research Foundation
IPC: C08F26/06 , C08F26/02 , C08F22/26 , C08F226/06 , C08F226/02 , C08F216/14 , C08F218/08 , C08F218/04 , C08F18/22 , C08F18/04 , C08F218/10
CPC classification number: C08F26/06 , C08F18/04 , C08F18/22 , C08F22/26 , C08F26/02 , C08F216/1458 , C08F218/04 , C08F218/08 , C08F218/10 , C08F226/02 , C08F226/06
Abstract: Described herein are the synthesis and polymerization of a series of N-Boc-protected amino acid vinyl ester (BAAVE) monomers. Homopolymers and heteropolymers containing the monomers are described, particularly heteropolymers with vinyl ester monomers such as vinyl acetate. Deprotection can be used to produce hydrophilic and hydrophobic polymers that are particular useful in biological applications such as cellular delivery of biological materials.
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