公开(公告)号：US11490623B2

公开(公告)日：2022-11-08

申请号：US16846770

申请日：2020-04-13

申请人： Colgate-Palmolive Company ,  The Trustees of the University of Pennsylvania

发明人： Carl Myers ,  Carlo Daep ,  Lynette Zaidel ,  James Masters ,  Russell Composto ,  Hyun-Su Lee

IPC分类号： A01N47/44 ,  C11D3/37 ,  A61K31/785 ,  A61Q17/00 ,  C11D3/48 ,  A61Q11/00 ,  C08F126/02 ,  A61K8/91 ,  A01N25/08 ,  A61K8/81 ,  C08F8/30 ,  C09D5/14 ,  C09D139/00

摘要： Antimicrobial compositions and methods for depositing or coating the antimicrobial or antibacterial compositions on a substrate to prevent microbial adhesion are provided. The antimicrobial composition may include a cationic polymer having a poly-allylamine backbone. A portion of the poly-allylamine backbone may be functionalized with at least one of a guanidine functional group and a biguanide functional group.

公开(公告)号：US10239828B2

公开(公告)日：2019-03-26

申请号：US15459475

申请日：2017-03-15

申请人： 3M INNOVATIVE PROPERTIES COMPANY

发明人： Jerald K. Rasmussen ,  George W. Griesgraber ,  James I. Hembre

IPC分类号： C07C277/08 ,  C07C277/02 ,  C07C279/12 ,  D06M14/30 ,  G01N33/53 ,  C08F26/00 ,  C08F220/36 ,  C09D133/14 ,  B01J20/26 ,  B01J20/32 ,  C08F126/02 ,  G01N33/545 ,  B01J20/28 ,  C08F120/36 ,  C09D4/00 ,  G01N1/40

摘要： A process for preparing guanidino-functional, free radically polymerizable compounds comprises (a) combining (1) an amine compound comprising (i) at least one primary aliphatic amino group and (ii) at least one secondary aliphatic amino group, primary aromatic amino group, or secondary aromatic amino group, and (2) a guanylating agent; (b) allowing or inducing reaction of the amine compound and the guanylating agent to form a guanylated amine compound; (c) combining (1) the guanylated amine compound, and (2) a reactive monomer comprising (i) at least one ethylenically unsaturated group and (ii) at least one group that is reactive with an amino group; and (d) allowing or inducing reaction of the guanylated amine compound and the reactive monomer to form a guanidino-functional, free radically polymerizable compound.

公开(公告)号：US09925215B1

公开(公告)日：2018-03-27

申请号：US15792962

申请日：2017-10-25

申请人： UNIWERSYTET JAGIELLONSKI

发明人： Maria Nowakowska ,  Krzysztof Szczubialka ,  Krzysztof Pyrc ,  Justyna Ciejka ,  Magdalena Wytrwal ,  Aleksandra Milewska

IPC分类号： A61K31/795 ,  C08F126/02

CPC分类号： A61K31/795 ,  A61K9/0073 ,  C08F8/36 ,  C08F8/44 ,  C08F126/02 ,  C08F8/00

摘要： The subject of the invention is an N-sulfonic polyallylamine derivative (NSPAH) with Formula 1, wherein R is —SO3− or —H, and n is an integer from 150 to 15000; an application of the N-sulfonic polyallylamine derivative as a medicine, particularly for prevention and treatment of respiratory tract infections caused by the human metapneumovirus (hMPV), respiratory tract infections caused by the human rhinoviruses (HRV), and infections caused by the influenza A virus; as well as a pharmaceutical composition comprising the N-sulfonic polyallylamine derivative and application thereof.

公开(公告)号：US20170240591A1

公开(公告)日：2017-08-24

申请号：US15591490

申请日：2017-05-10

申请人： 3M INNOVATIVE PROPERTIES COMPANY

发明人： Jerald K. Rasmussen ,  Kannan Seshadri ,  Robert T. Fitzsimons, JR. ,  James I. Hembre ,  Catherine A. Bothof ,  Erin A. Satterwhite ,  George W. Griesgraber ,  Yi He ,  Louis C. Haddad

IPC分类号： C07K1/14 ,  B01D21/01 ,  C08F126/02 ,  C08F120/60 ,  C12N11/08 ,  C08G73/02

CPC分类号： C07K1/14 ,  B01D21/01 ,  C08F120/60 ,  C08F126/02 ,  C08G69/10 ,  C08G73/0206 ,  C08G73/022 ,  C08G73/028 ,  C08L77/04 ,  C08L79/02 ,  C08L83/08 ,  C12N7/02 ,  C12N11/08 ,  G01N33/54393 ,  G01N33/545 ,  Y10T428/249978 ,  Y10T428/249991 ,  Y10T428/2935 ,  Y10T428/2998 ,  Y10T442/20

摘要： Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.

公开(公告)号：US20170216347A1

公开(公告)日：2017-08-03

申请号：US15329324

申请日：2015-07-29

申请人： UNIWERSYTET JAGIELLONSKI

发明人： MARIA NOWAKOWSKA ,  KRZYSZTOF SZCZUBIALKA ,  KRZYSZTOF PYRC ,  JUSTYNA CIEJKA ,  MAGDALENA WYTRWAL ,  ALEKSANDRA MILEWSKA

IPC分类号： A61K31/795 ,  C08F126/02

CPC分类号： A61K31/795 ,  A61K9/0073 ,  C08F8/36 ,  C08F8/44 ,  C08F126/02 ,  C08F8/00

摘要： The subject of the invention is an N-sulfonic polyallylamine derivative (NSPAH) with Formula 1, wherein R is —SO3− or —H, and n is an integer from 150 to 15000; an application of the N-sulfonic polyallylamine derivative as a medicine, particularly for prevention and treatment of respiratory tract infections caused by the human metapneumovirus (hMPV), respiratory tract infections caused by the human rhinoviruses (HRV), and infections caused by the influenza A virus; as well as a pharmaceutical composition comprising the N-sulfonic polyallylamine derivative and application thereof.

公开(公告)号：US20160176995A1

公开(公告)日：2016-06-23

申请号：US14969918

申请日：2015-12-15

申请人： Cytec Industries Inc

发明人： Airong Song ,  Lei Zhang ,  Douglas Cywar ,  Haunn-Lin Tony Chen ,  Matthew Taylor

IPC分类号： C08F126/02 ,  C02F1/68

摘要： Silicon containing polyamine scale inhibitors derived from poly(primary amine)s are disclosed. The scale inhibitors can be used to reduce siliceous scale formation in industrial process streams such as alumina recovery process streams, nuclear waste streams and kraft paper mill effluent streams.

摘要翻译： 公开了衍生自聚（伯胺）的含硅多胺垢抑制剂。 减阻剂可用于减少工业过程流中的硅质垢形成，例如氧化铝回收工艺流，核废料流和牛皮纸浆流出物流。

公开(公告)号：US20160096802A1

公开(公告)日：2016-04-07

申请号：US14787930

申请日：2014-06-12

申请人： 3M INNOVATIVE PROPERTIES COMPANY

发明人： Jerald K. Rasmussen ,  George W. Griesgraber ,  James I. Hembre

IPC分类号： C07C277/08 ,  C08F126/02 ,  G01N33/545 ,  C07C279/12

CPC分类号： C07C277/08 ,  B01J20/261 ,  B01J20/28033 ,  B01J20/327 ,  C07C277/02 ,  C07C279/12 ,  C08F26/00 ,  C08F120/36 ,  C08F126/02 ,  C08F220/36 ,  C09D4/00 ,  C09D133/14 ,  D06M14/30 ,  G01N1/405 ,  G01N33/53 ,  G01N33/545 ,  C07C279/08

摘要： A process for preparing guanidino-functional, free radically polymerizable compounds comprises (a) combining (1) an amine compound comprising (i) at least one primary aliphatic amino group and (ii) at least one secondary aliphatic amino group, primary aromatic amino group, or secondary aromatic amino group, and (2) a guanylating agent; (b) allowing or inducing reaction of the amine compound and the guanylating agent to form a guanylated amine compound; (c) combining (1) the guanylated amine compound, and (2) a reactive monomer comprising (i) at least one ethylenically unsaturated group and (ii) at least one group that is reactive with an amino group; and (d) allowing or inducing reaction of the guanylated amine compound and the reactive monomer to form a guanidino-functional, free radically polymerizable compound.

摘要翻译： 制备胍基官能的可自由基聚合化合物的方法包括（a）将（1）胺化合物（i）至少包含一个伯脂肪族氨基和（ii）至少一个仲脂肪族氨基，伯芳族氨基 或仲芳族氨基，和（2）脒基化剂; （b）允许或诱导胺化合物和脒基化剂反应形成胍化胺化合物; （c）将（1）胍化胺化合物和（2）包含（i）至少一种烯属不饱和基团和（ii）至少一个与氨基反应的基团的反应性单体的组合; 和（d）允许或诱导胍化胺化合物和反应性单体的反应以形成胍基官能的可自由基聚合的化合物。

公开(公告)号：US20160024233A1

公开(公告)日：2016-01-28

申请号：US14776059

申请日：2014-03-12

申请人： GENZYME CORPORATION

发明人： Stephen Randall HOLMES-FARLEY ,  Pradeep K. DHAL ,  Magnus BESEV ,  Robert J. MILLER ,  Andrew T. PAPOULIS

IPC分类号： C08F126/02

CPC分类号： C08F126/02 ,  A61K31/785

摘要： Sequestrants of AGE precursors comprise amines separated by 2, 3 or 4 carbons. Sequestrants of AGE precursors can be used as pharmaceutical agents and in pharmaceutical compositions. The sequestrants of AGE precursors are particularly useful binding AGE precursors and dietary dicarbonyls in mammals in the gastrointestinal tract for the treatment of ailments such as diabetic nephropathy, chronic renal disease, atherosclerosis, stroke, cataracts, and Alzheimer's disease.

摘要翻译： AGE前体的螯合剂包括被2,3或4个碳分开的胺。 AGE前体的螯合剂可用作药剂和药物组合物。 AGE前体的多价螯合剂在胃肠道的哺乳动物中特异性地结合AGE前体和膳食二羰基用于治疗疾病如糖尿病性肾病，慢性肾脏病，动脉粥样硬化，中风，白内障和阿尔茨海默病。

公开(公告)号：US09217048B2

公开(公告)日：2015-12-22

申请号：US14183791

申请日：2014-02-19

申请人： EMD Millipore Corporation

发明人： Jad Jaber ,  Wilson Moya ,  James Hamzik ,  Arezki Boudif ,  Yu Zhang ,  Neil Soice ,  John Charkoudian ,  Nripen Singh

IPC分类号： C08F126/00 ,  C08F126/02 ,  C07K1/30 ,  C07K1/32 ,  C08F8/00 ,  C08F8/02 ,  C07K16/00

CPC分类号： B01J41/14 ,  B01J41/13 ,  C07K1/30 ,  C07K1/32 ,  C07K16/00 ,  C07K2317/10 ,  C08F8/00 ,  C08F8/02 ,  C08F126/02 ,  C08F26/02

摘要： The present invention provides novel and improved stimulus responsive polymers and methods of using the same for the purification of biomolecules.

摘要翻译： 本发明提供了新的和改进的刺激响应聚合物及其用于生物分子纯化的方法。

公开(公告)号：US08829154B2

公开(公告)日：2014-09-09

申请号：US14017844

申请日：2013-09-04

申请人： Phillip B. Messersmith ,  Haeshin Lee ,  Yuhan Lee ,  Zhongqiang Liu ,  Lesley Hamming

发明人： Phillip B. Messersmith ,  Haeshin Lee ,  Yuhan Lee ,  Zhongqiang Liu ,  Lesley Hamming

IPC分类号： C08G63/66 ,  B05D7/00 ,  C08B37/08 ,  C08F126/02 ,  C08G69/48 ,  C08G85/00 ,  C08G83/00 ,  B05D3/00 ,  C08F26/02 ,  C08G65/48 ,  C08G73/04

CPC分类号： C08F126/02 ,  B05D7/52 ,  C08B37/0072 ,  C08F26/02 ,  C08G69/48 ,  C08G73/0206 ,  C08G83/00 ,  C08G85/004

摘要： The present invention provides a simple, non-destructive and versatile method that enables layer-by-layer (LbL) assembly to be performed on virtually any substrate. A novel catechol-functionalized polymer which adsorbs to virtually all surfaces and can serve as a platform for LbL assembly in a surface-independent fashion is also provided.

摘要翻译： 本发明提供了一种简单的，非破坏性和通用的方法，其能够在几乎任何基底上执行逐层（LbL）组件。 还提供了一种新颖的儿茶酚官能化聚合物，其吸附到几乎所有表面并且可以作为以表面无关的方式用于LbL组装的平台。