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    Method for producing a bioactive bone cement and bone cement kit
    1.
    发明授权
    Method for producing a bioactive bone cement and bone cement kit 失效
    生物活性骨水泥和骨水泥试剂盒的生产方法

    公开(公告)号：US07109254B2

    公开(公告)日：2006-09-19

    申请号：US10480886

    申请日：2002-06-14

    申请人： Wolf-Dieter Müller ,  Emil Nagel ,  Georg Berger

    发明人： Wolf-Dieter Müller ,  Emil Nagel ,  Georg Berger

    IPC分类号： A61K6/08 ,  A61K6/83 ,  C08K5/52 ,  C08K3/16 ,  C08K3/20 ,  C08K3/22

    CPC分类号： A61L24/0084 ,  A61L24/0089 ,  A61L27/446 ,  A61L27/46 ,  A61L2430/02 ,  C08L33/12

    摘要： A method for producing a bioactive bone cement and a bone cement kit for anchoring artificial joints and for filling out bone defects. The method avoids polymerization-linked by-products and disadvantageous effects, while at the same time providing the bone cement with long-term stability. The inventive method uses a monomer-free polymethylmethacrylate, which is mixed with a suitable non-toxic solvent, and a bioactive, vitreous-crystalline material with a particle size ranging from >20 to 200 μm, having 15–45 wt. % CaO, 40–45 wt. % P2O5, 10–40 wt. % ZrO2 and 0.7–3.5 wt. % fluoride, having apatite and calcium zircon phosphate as main crystal phases and a glass phase as an auxiliary component until a flowable mixture is obtained. The invention also relates to a bone cement kit having said components.

    摘要翻译： 生物活性骨水泥的制造方法和用于锚定人造关节并填充骨缺损的骨水泥试剂盒。 该方法避免了与聚合有关的副产物和不利影响，同时为骨水泥提供长期的稳定性。 本发明的方法使用与合适的无毒溶剂混合的无单体聚甲基丙烯酸甲酯和粒度范围> 20至200μm的生物活性玻璃态结晶材料，其具有15-45wt。 ％CaO，40-45wt。 ％P 2 O 5，10-40重量％ ％ZrO 2和0.7-3.5wt。 具有磷灰石和磷酸钙锆作为主要结晶相的氟化物，玻璃相作为辅助成分，直到得到可流动的混合物。 本发明还涉及具有所述组分的骨水泥试剂盒。

    Temporary adhesive for metal-metal and metal-ceramic bonds
    2.
    发明授权
    Temporary adhesive for metal-metal and metal-ceramic bonds 失效
    金属 - 金属和金属 - 陶瓷键的临时粘合剂

    公开(公告)号：US07223808B2

    公开(公告)日：2007-05-29

    申请号：US10480917

    申请日：2002-06-14

    申请人： Wolf-Dieter Müller ,  Georg Berger ,  Emil Nagel ,  Klaus-Peter Lange

    发明人： Wolf-Dieter Müller ,  Georg Berger ,  Emil Nagel ,  Klaus-Peter Lange

    IPC分类号： C08K3/32 ,  A61K6/00 ,  A61F2/28 ,  C03C3/247

    CPC分类号： A61L27/46 ,  A61K6/0023 ,  A61K6/0273 ,  A61K6/033 ,  A61L24/0084 ,  A61L24/0089 ,  A61L24/06 ,  A61L27/446 ,  C08L33/12 ,  C08L33/00

    摘要： The invention relates to a method for the production of an adhesive and an adhesive kit for joining similar or different metal surfaces or ceramics, especially in the field of biomedicine. The objective of the invention is to avoid polymerization-linked by-products and disadvantageous effects, in addition to enabling a temporary biocompatible bond between metal and metal or metal and ceramics. The inventive method consist in using a monomer-free polymethylmethacrylate which is mixed with a suitable, non-toxic solvent and a bioactive vitreous-crystalline material with a particle size ranging from 0.05–20μ, consisting of 15–45 wt. % CaO, 40–45 wt. % P2O5, 10–40 wt. % ZrO2 and 0.7–3.5 wt. % fluoride, having apatite and calcium zircon phosphate as main crystal phases and a glass phase as an auxiliary component until a flowable mixture is obtained. The invention also relates to an adhesive kit consisting of said components. Sufficient amounts of resistance are obtained for a temporary bond, enabling the bond to be neutralized when desired.

    摘要翻译： 本发明涉及生产用于连接类似或不同金属表面或陶瓷的粘合剂和粘合剂试剂盒的方法，特别是在生物医学领域。 本发明的目的是除了能够在金属和金属或金属和陶瓷之间实现临时的生物相容性结合之外，避免聚合相互作用的副产物和不利影响。 本发明的方法包括使用无单体的聚甲基丙烯酸甲酯，其与合适的无毒溶剂和粒度范围为0.05-20mu的生物活性玻璃结晶材料混合，其由15-45wt。 ％CaO，40-45wt。 ％P 2 O 5，10-40重量％ ％ZrO 2和0.7-3.5wt。 具有磷灰石和磷酸钙锆作为主要结晶相的氟化物，玻璃相作为辅助成分，直到得到可流动的混合物。 本发明还涉及由所述组分组成的粘合试剂盒。 获得足够量的电阻用于临时键，使得当需要时可以中和该键。

    Apparatus for treating plastic parts for use in dental and orthodontic applications
    5.
    发明授权
    Apparatus for treating plastic parts for use in dental and orthodontic applications 失效
    用于治疗用于牙科和正畸应用的塑料部件的装置

    公开(公告)号：US4771162A

    公开(公告)日：1988-09-13

    申请号：US941618

    申请日：1986-12-15

    申请人： Rolf Schatz ,  Bernhard Link ,  Emil Nagel

    发明人： Rolf Schatz ,  Bernhard Link ,  Emil Nagel

    IPC分类号： B29B13/02 ,  A61C13/14 ,  B29C35/02 ,  B29C35/04 ,  C08F2/02 ,  F27B5/04

    CPC分类号： A61C13/14 ,  B29C35/0233 ,  B29C35/04 ,  B29L2031/7536

    摘要： A device for treating plastic parts for use in dental and orthodontic applications includes a pressure receptacle which has walls which define a hollow interior with an opening which is closable by a cover or lid. A support for material to be treated is placed within the hollow interior at a spaced location in the interior walls and adjacent a heating device which is advantageously an electric heating element. The device includes a rotatable fan which is advantageously mounted on the vessel as a shaft which extends through the vessel interior and carries a rotatable fan which is rotated so as to direct a gas such as air past objects held on a support and past the heater which maintains the circulating gases at a temperature which permits polymerization of the parts. The heating air is continuously circulated and it is heated by the heater sufficiently to maintain a selected polymerization temperature.

    摘要翻译： 用于处理用于牙科和正畸使用的塑料部件的装置包括压力容器，该压力容器具有限定中空内部的壁，该开口具有可由盖或盖关闭的开口。 将待处理材料的支撑件放置在中空内部中，在内壁的间隔位置处并且邻近加热装置，其有利地是电加热元件。 该装置包括可旋转的风扇，其有利地安装在容器上作为轴，其延伸穿过容器内部并且携带旋转的可旋转风扇，所述风扇被旋转以便引导气体例如空气通过保持在支撑件上的物体并经过加热器， 将循环气体保持在允许部件聚合的温度下。 加热空气连续循环，并被加热器充分加热以保持所选择的聚合温度。