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公开(公告)号：US20060199223A1
公开(公告)日：2006-09-07
申请号：US11326852
申请日：2006-01-06
IPC分类号： G01N33/53 , C12Q1/66 , C07D277/84 , C07D263/60 , C07K16/46
CPC分类号： C07D209/60 , G01N33/533
摘要： The present invention relates to novel chemiluminescent compounds, to a method for synthesizing these compounds, to derivatives and conjugates comprising these compounds, to the use of these compounds or conjugates thereof in chemiluminescence based assays, especially in immunoassays.
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公开(公告)号：US07262306B2
公开(公告)日：2007-08-28
申请号：US11326852
申请日：2006-01-06
IPC分类号： C07D209/56 , G01N33/53 , C12Q1/66 , C07K16/00
CPC分类号： C07D209/60 , G01N33/533
摘要： The present invention relates to novel chemiluminescent compounds, to a method for synthesizing these compounds, to derivatives and conjugates comprising these compounds, to the use of these compounds or conjugates thereof in chemiluminescence based assays, especially in immunoassays.
摘要翻译： 本发明涉及新颖的化学发光化合物，涉及将这些化合物合成的方法，包含这些化合物的衍生物和缀合物，以使用这些化合物或其缀合物在基于化学发光的测定中，特别是在免疫测定中。
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公开(公告)号：US20070196852A1
公开(公告)日：2007-08-23
申请号：US11707399
申请日：2007-02-16
申请人： Dieter Heindl , Frank Bergmann , Hans-Peter Josel , Dirk Kessler , Gunter Lampert , Christian Weilke
发明人： Dieter Heindl , Frank Bergmann , Hans-Peter Josel , Dirk Kessler , Gunter Lampert , Christian Weilke
摘要： The current invention restates substituted indole nucleosides as both terminal as well as internal building blocks of labeled oligonucleotide probes for the detection, analysis and quantitation of nucleic acids. The substituent comprises a linker and a detectable group or a linker and a reactive group for post synthesis coupling. These modified nucleosides grant access to a wide application area. These new substituted indole nucleosides can be used as labeling reagents for the facile preparation of e.g. optimized hybridization probes, Taqman-probes, or molecular beacon probes.
摘要翻译： 本发明将取代的吲哚核苷作为两个末端以及用于核酸检测，分析和定量的标记的寡核苷酸探针的内部构建块重述。 取代基包括接头和可检测的基团或接头以及用于后合成偶联的反应性基团。 这些修饰的核苷允许进入广泛的应用领域。 这些新的取代的吲哚核苷可以用作标记试剂，用于容易地制备例如 优化的杂交探针，Taqman探针或分子信标探针。
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公开(公告)号：US07759470B2
公开(公告)日：2010-07-20
申请号：US11707399
申请日：2007-02-16
申请人： Dieter Heindl , Frank Bergmann , Hans-Peter Josel , Dirk Kessler , Gunter Lampert , Christian Weilke
发明人： Dieter Heindl , Frank Bergmann , Hans-Peter Josel , Dirk Kessler , Gunter Lampert , Christian Weilke
摘要： The current invention restates substituted indole nucleosides as both terminal as well as internal building blocks of labeled oligonucleotide probes for the detection, analysis and quantitation of nucleic acids. The substituent comprises a linker and a detectable group or a linker and a reactive group for post synthesis coupling. These modified nucleosides grant access to a wide application area. These new substituted indole nucleosides can be used as labeling reagents for the facile preparation of e.g. optimized hybridization probes, Taqman-probes, or molecular beacon probes.
摘要翻译： 本发明将取代的吲哚核苷作为两个末端以及用于核酸检测，分析和定量的标记的寡核苷酸探针的内部构建块重述。 取代基包括接头和可检测的基团或接头以及用于后合成偶联的反应性基团。 这些修饰的核苷允许进入广泛的应用领域。 这些新的取代的吲哚核苷可以用作标记试剂，用于容易地制备例如 优化的杂交探针，Taqman探针或分子信标探针。
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