公开(公告)号：US20240230632A9

公开(公告)日：2024-07-11

申请号：US18403481

申请日：2024-01-03

Applicant: Yantai AusBio Laboratories Co., Ltd.

Inventor： Zhaoqiang Wang ,  Wolfgang Mann ,  Wolfgang Heimberg

IPC: G01N33/543 ,  B01L9/00 ,  B03C1/00 ,  B03C1/01 ,  B03C1/28 ,  B03C1/30 ,  B04B5/04 ,  B04B7/04 ,  B04B15/02 ,  B08B3/02 ,  B08B3/04 ,  B08B3/06 ,  B08B3/10 ,  B08B9/00 ,  G01N35/02

CPC classification number: G01N33/54326 ,  B01L9/523 ,  B01L13/02 ,  B03C1/002 ,  B03C1/01 ,  B03C1/288 ,  B03C1/30 ,  B04B5/0407 ,  B04B5/0414 ,  B04B7/04 ,  B04B15/02 ,  B08B3/02 ,  B08B3/04 ,  B08B3/06 ,  B08B3/10 ,  B08B9/00 ,  G01N33/54366 ,  G01N35/028 ,  B01L2300/0829 ,  B01L2400/0409 ,  B04B2011/046

Abstract: A centrifuge for cleaning a reaction vessel unit, having a rotor for holding at least one reaction vessel unit with its opening(s) directed outwardly, a motor for rotating the rotor around a rotation axis, a housing having a substantially cylindrical inner surface, wherein a drain is provided for discharging fluid expelled from the reaction vessel unit, wherein a gap is provided between the inner surface and the rotor so that by rotating the rotor a wind is generated which drives the expelled fluid on the inner surface to the drain wherein an aspiration pump is connected to the drain for discharging fluid.

公开(公告)号：US10895570B2

公开(公告)日：2021-01-19

申请号：US15028421

申请日：2014-10-07

Applicant: Yantai AusBio Laboratories Co., Ltd.

Inventor： Zhaoqiang Wang ,  Wolfgang Mann

IPC: G01N33/559 ,  G01N33/53 ,  G01N33/543 ,  G01N21/25 ,  G01N21/82 ,  B01L3/00

Abstract: The invention relates to a method for determining the result of an agglutination reaction and a microplate used in such a method. Agglutinated and non-agglutinated sample material is separated by means of a separation material such as gel material or a bead matrix in a centrifugation step. Whether an agglutination reaction took place or not is determined by comparing the color intensities and/or the gray levels of images of the top side and the bottom side of the respective reaction vessel. Comparing the color intensities and/or the gray levels of the two images makes the automatic determination reliable and stable. Furthermore, the reaction wells are arranged in a two-dimensional array which provides a high throughput.

公开(公告)号：US20160252499A1

公开(公告)日：2016-09-01

申请号：US15028421

申请日：2014-10-07

Applicant: YANTAI AUSBIO LABORATORIES CO., LTD.

Inventor： Zhaoqiang Wang ,  Wolfgang Mann

IPC: G01N33/53

Abstract: The invention relates to a method for determining the result of an agglutination reaction and a microplate used in such a method. Agglutinated and non-agglutinated sample material is separated by means of a separation material such as gel material or a bead matrix in a centrifugation step. Whether an agglutination reaction took place or not is determined by comparing the color intensities and/or the gray levels of images of the top side and the bottom side of the respective reaction vessel. Comparing the color intensities and/or the gray levels of the two images makes the automatic determination reliable and stable. Furthermore, the reaction wells are arranged in a two-dimensional array which provides a high throughput.

Abstract translation: 本发明涉及用于确定凝集反应结果的方法和在这种方法中使用的微板。 在离心步骤中，通过分离材料如凝胶材料或珠粒基质分离凝集和未凝集的样品材料。 通过比较各反应容器的顶侧和底侧的图像的颜色强度和/或灰度等级来确定凝集反应是否发生。 比较两个图像的颜色强度和/或灰度级使得自动测定可靠稳定。 此外，反应孔被排列成提供高通量的二维阵列。

公开(公告)号：US20190170740A1

公开(公告)日：2019-06-06

申请号：US16256021

申请日：2019-01-24

Applicant: Yantai AusBio Laboratories Co., Ltd.

Inventor： Zhaoqiang Wang ,  Wolfgang Mann ,  Wolfgang Heimberg

IPC: G01N33/543 ,  B08B3/06 ,  B03C1/00 ,  B08B3/04 ,  B04B15/02 ,  B04B7/04 ,  B08B3/02 ,  B03C1/01 ,  B03C1/28 ,  B03C1/30 ,  B01L99/00 ,  G01N35/02 ,  B04B5/04 ,  B08B9/00 ,  B08B3/10

Abstract: A centrifuge for cleaning a reaction vessel unit, having a rotor for holding at least one reaction vessel unit with its opening(s) directed outwardly, a motor for rotating the rotor around a rotation axis, a housing having a substantially cylindrical inner surface, wherein a drain is provided for discharging fluid expelled from the reaction vessel unit, wherein a gap is provided between the inner surface and the rotor so that by rotating the rotor a wind is generated which drives the expelled fluid on the inner surface to the drain wherein an aspiration pump is connected to the drain for discharging fluid.

公开(公告)号：US20190154675A1

公开(公告)日：2019-05-23

申请号：US16255052

申请日：2019-01-23

Applicant: Yantai AusBio Laboratories Co., Ltd.

Inventor： Zhaoqiang Wang ,  Wolfgang Mann ,  Wolfgang Heimberg

IPC: G01N33/543 ,  B08B3/06 ,  B03C1/00 ,  B08B3/04 ,  B04B15/02 ,  B04B7/04 ,  B08B3/02 ,  B03C1/01 ,  B03C1/28 ,  B03C1/30 ,  B01L99/00 ,  G01N35/02 ,  B04B5/04 ,  B08B9/00 ,  B08B3/10

Abstract: A centrifuge for cleaning a reaction vessel unit, having a rotor for holding at least one reaction vessel unit with its opening(s) directed outwardly, a motor for rotating the rotor around a rotation axis, a housing having a substantially cylindrical inner surface, wherein a drain is provided for discharging fluid expelled from the reaction vessel unit, wherein a gap is provided between the inner surface and the rotor so that by rotating the rotor a wind is generated which drives the expelled fluid on the inner surface to the drain wherein an aspiration pump is connected to the drain for discharging fluid.

公开(公告)号：US20190145968A1

公开(公告)日：2019-05-16

申请号：US16243644

申请日：2019-01-09

Applicant: Yantai AusBio Laboratories Co., Ltd.

Inventor： Zhaoqiang Wang ,  Wolfgang Mann ,  Wolfgang Heimberg

IPC: G01N33/543 ,  B08B3/06 ,  B03C1/00 ,  B08B3/04 ,  B04B15/02 ,  B04B7/04 ,  B08B3/02 ,  B03C1/01 ,  B03C1/28 ,  B03C1/30 ,  B01L99/00 ,  G01N35/02 ,  B04B5/04 ,  B08B9/00 ,  B08B3/10

Abstract: A centrifuge for cleaning a reaction vessel unit, having a rotor for holding at least one reaction vessel unit with its opening(s) directed outwardly, a motor for rotating the rotor around a rotation axis, a housing having a substantially cylindrical inner surface, wherein a drain is provided for discharging fluid expelled from the reaction vessel unit, wherein a gap is provided between the inner surface and the rotor so that by rotating the rotor a wind is generated which drives the expelled fluid on the inner surface to the drain wherein an aspiration pump is connected to the drain for discharging fluid.

公开(公告)号：US20240142443A1

公开(公告)日：2024-05-02

申请号：US18408845

申请日：2024-01-10

Applicant: Yantai AusBio Laboratories Co., Ltd.

Inventor： Zhaoqiang Wang ,  Wolfgang Mann ,  Wolfgang Heimberg

IPC: G01N33/543 ,  B01L9/00 ,  B03C1/00 ,  B03C1/01 ,  B03C1/28 ,  B03C1/30 ,  B04B5/04 ,  B04B7/04 ,  B04B15/02 ,  B08B3/02 ,  B08B3/04 ,  B08B3/06 ,  B08B3/10 ,  B08B9/00 ,  G01N35/02

CPC classification number: G01N33/54326 ,  B01L9/523 ,  B01L13/02 ,  B03C1/002 ,  B03C1/01 ,  B03C1/288 ,  B03C1/30 ,  B04B5/0407 ,  B04B5/0414 ,  B04B7/04 ,  B04B15/02 ,  B08B3/02 ,  B08B3/04 ,  B08B3/06 ,  B08B3/10 ,  B08B9/00 ,  G01N33/54366 ,  G01N35/028 ,  B01L2300/0829 ,  B01L2400/0409 ,  B04B2011/046

Abstract: A centrifuge for cleaning a reaction vessel unit, having a rotor for holding at least one reaction vessel unit with its opening(s) directed outwardly, a motor for rotating the rotor around a rotation axis, a housing having a substantially cylindrical inner surface, wherein a drain is provided for discharging fluid expelled from the reaction vessel unit, wherein a gap is provided between the inner surface and the rotor so that by rotating the rotor a wind is generated which drives the expelled fluid on the inner surface to the drain wherein an aspiration pump is connected to the drain for discharging fluid.

公开(公告)号：US10928387B2

公开(公告)日：2021-02-23

申请号：US16250092

申请日：2019-01-17

Applicant: Yantai AusBio Laboratories Co., Ltd.

Inventor： Zhaoqiang Wang ,  Wolfgang Mann ,  Wolfgang Heimberg

IPC: G01N33/543 ,  B08B3/10 ,  B08B9/00 ,  B04B5/04 ,  G01N35/02 ,  B03C1/00 ,  B03C1/01 ,  B03C1/28 ,  B03C1/30 ,  B04B7/04 ,  B04B15/02 ,  B01L9/00 ,  B08B3/02 ,  B08B3/04 ,  B08B3/06 ,  B04B11/04 ,  G01N35/04 ,  B01L3/00

Abstract: A centrifuge for washing magnetic beads in a reaction vessel unit that includes at least one opening, having a housing including an inner surface and a drain, a rotor disposed within the housing, the rotor being configured to hold a reaction vessel unit with its opening(s) directed outwardly toward the inner surface of the housing, a motor coupled with the rotor to rotate around a horizontal rotation axis, and a magnetic element arranged in the rotor to apply a magnetic field to one or more reaction vessels of a reaction vessel unit held by the rotor.

公开(公告)号：US10338063B2

公开(公告)日：2019-07-02

申请号：US14910681

申请日：2014-08-06

Applicant: Yantai AusBio Laboratories Co., Ltd.

Inventor： Zhaoqiang Wang ,  Wolfgang Mann ,  Wolfgang Heimberg

IPC: B03C1/00 ,  B03C1/01 ,  B03C1/28 ,  B03C1/30 ,  B04B5/04 ,  B04B7/04 ,  B08B3/02 ,  B08B3/04 ,  B08B3/06 ,  B08B3/10 ,  B08B9/00 ,  B01L99/00 ,  B04B11/04 ,  B04B15/02 ,  G01N35/02 ,  G01N35/04 ,  G01N33/543

Abstract: A centrifuge for cleaning a reaction vessel unit, having a rotor for holding at least one reaction vessel unit with its opening(s) directed outwardly, a motor for rotating the rotor around a rotation axis, a housing having a substantially cylindrical inner surface, wherein a drain is provided for discharging fluid expelled from the reaction vessel unit, wherein a gap is provided between the inner surface and the rotor so that by rotating the rotor a wind is generated which drives the expelled fluid on the inner surface to the drain wherein an aspiration pump is connected to the drain for discharging fluid.

公开(公告)号：US20190145969A1

公开(公告)日：2019-05-16

申请号：US16250092

申请日：2019-01-17

Applicant: Yantai AusBio Laboratories Co., Ltd.

Inventor： Zhaoqiang Wang ,  Wolfgang Mann ,  Wolfgang Heimberg

IPC: G01N33/543 ,  B08B3/06 ,  B03C1/00 ,  B08B3/04 ,  B04B15/02 ,  B04B7/04 ,  B08B3/02 ,  B03C1/01 ,  B03C1/28 ,  B03C1/30 ,  B01L99/00 ,  G01N35/02 ,  B04B5/04 ,  B08B9/00 ,  B08B3/10

Abstract: A centrifuge for cleaning a reaction vessel unit, having a rotor for holding at least one reaction vessel unit with its opening(s) directed outwardly, a motor for rotating the rotor around a rotation axis, a housing having a substantially cylindrical inner surface, wherein a drain is provided for discharging fluid expelled from the reaction vessel unit, wherein a gap is provided between the inner surface and the rotor so that by rotating the rotor a wind is generated which drives the expelled fluid on the inner surface to the drain wherein an aspiration pump is connected to the drain for discharging fluid.