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公开(公告)号：US07994139B2
公开(公告)日：2011-08-09
申请号：US12398866
申请日：2009-03-05
申请人： Yarlagadda S. Babu , Pooran Chand , Pravin Kotian , Minwan Wu , V. Satish Kumar
发明人： Yarlagadda S. Babu , Pooran Chand , Pravin Kotian , Minwan Wu , V. Satish Kumar
CPC分类号： C12N9/99 , C07D487/06 , C07D491/06 , C07D498/06 , C12N9/1241
摘要： The invention provides compounds of Formula I: as described herein, as well as pharmaceutical compositions comprising the compounds, and synthetic methods and intermediates that are useful for preparing the compounds. The compounds of Formula (I) are useful as anti-viral agents and/or as anti-cancer agents.
摘要翻译： 本发明提供式I化合物：如本文所述，以及包含该化合物的药物组合物，以及可用于制备化合物的合成方法和中间体。 式（I）的化合物可用作抗病毒剂和/或作为抗癌剂。
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公开(公告)号：US20120142617A1
公开(公告)日：2012-06-07
申请号：US13181078
申请日：2011-07-12
申请人： Yarlagadda S. Babu , Pooran Chand , Pravin Kotian , Minwan Wu , V. Satish Kumar
发明人： Yarlagadda S. Babu , Pooran Chand , Pravin Kotian , Minwan Wu , V. Satish Kumar
IPC分类号： A61K31/706 , C07H11/04 , A61K31/7068 , A61P35/00 , C12N9/99 , C07H7/06 , A61P31/12
CPC分类号： C12N9/99 , C07D487/06 , C07D491/06 , C07D498/06 , C12N9/1241
摘要： The invention provides compounds of Formula I: as described herein, as well as pharmaceutical compositions comprising the compounds, and synthetic methods and intermediates that are useful for preparing the compounds. The compounds of Formula (I) are useful as anti-viral agents and/or as anti-cancer agents.
摘要翻译： 本发明提供式I化合物：如本文所述，以及包含该化合物的药物组合物，以及可用于制备化合物的合成方法和中间体。 式（I）的化合物可用作抗病毒剂和/或作为抗癌剂。
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公开(公告)号：US20090227524A1
公开(公告)日：2009-09-10
申请号：US12398866
申请日：2009-03-05
申请人： Yarlagadda S. Babu , Pooran Chand , Pravin Kotian , Minwan Wu , V. Satish Kumar
发明人： Yarlagadda S. Babu , Pooran Chand , Pravin Kotian , Minwan Wu , V. Satish Kumar
IPC分类号： A61K31/7052 , C07H7/00 , C12N9/99 , A61P35/00 , A61P31/12
CPC分类号： C12N9/99 , C07D487/06 , C07D491/06 , C07D498/06 , C12N9/1241
摘要： The invention provides compounds of Formula I: as described herein, as well as pharmaceutical compositions comprising the compounds, and synthetic methods and intermediates that are useful for preparing the compounds. The compounds of Formula (I) are useful as anti-viral agents and/or as anti-cancer agents.
摘要翻译： 本发明提供式I化合物：如本文所述，以及包含该化合物的药物组合物，以及可用于制备化合物的合成方法和中间体。 式（I）的化合物可用作抗病毒剂和/或作为抗癌剂。
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公开(公告)号：US20120213735A1
公开(公告)日：2012-08-23
申请号：US13372067
申请日：2012-02-13
申请人： Yarlagadda S. Babu , Pooran Chand , Minwan Wu , Pravin L. Kotian , V. Satish Kumar , Tsu-Hsing Lin , Yahya El-Kattan , Ajit K. Ghosh
发明人： Yarlagadda S. Babu , Pooran Chand , Minwan Wu , Pravin L. Kotian , V. Satish Kumar , Tsu-Hsing Lin , Yahya El-Kattan , Ajit K. Ghosh
IPC分类号： A61K31/7068 , A61K38/21 , A61P31/20 , A61K31/7064 , A61P35/00 , C07H19/24 , C12N9/99
CPC分类号： C07D495/04 , A61K31/675 , A61K31/7076 , A61K38/212 , A61K38/2292 , C07D491/048 , C07D493/04 , C07F9/6561 , C07H7/06 , C07H19/22 , Y02A50/393 , Y02A50/465 , A61K2300/00
摘要： The invention provides compounds of formula I, II, and III as described herein, as well as pharmaceutical compositions comprising the compounds, and synthetic methods and intermediates that are useful for preparing the compounds. The compounds of formula I, II, and III are useful as anti-viral agents and/or as anti-cancer agents.
摘要翻译： 本发明提供了本文所述的式I，II和III的化合物，以及包含该化合物的药物组合物，以及可用于制备化合物的合成方法和中间体。 式I，II和III的化合物可用作抗病毒剂和/或作为抗癌剂。
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公开(公告)号：US20100015094A1
公开(公告)日：2010-01-21
申请号：US12522892
申请日：2008-01-11
IPC分类号： A61K38/21 , C07H19/20 , A61K31/706 , A61P31/00 , A61P35/04
CPC分类号： C07H19/23
摘要： The invention provides compounds of Formula (I), as described herein, as well as pharmaceutical compositions comprising the compounds, and synthetic methods and intermediates that are useful for preparing the compounds. The compounds of Formula (I) are useful as anti-viral agents and/or as anti-cancer agents.
摘要翻译： 本发明提供如本文所述的式（I）化合物以及包含该化合物的药物组合物，以及可用于制备化合物的合成方法和中间体。 式（I）的化合物可用作抗病毒剂和/或作为抗癌剂。
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公开(公告)号：US20100143300A1
公开(公告)日：2010-06-10
申请号：US12399521
申请日：2009-03-06
申请人： Yarlagadda S. Babu , Pooran Chand , Minwan Wu , Pravin L. Kotian , V. Satish Kumar , Tsu-Hsing Lin , Yahya El-Kattan , Ajit K. Ghosh
发明人： Yarlagadda S. Babu , Pooran Chand , Minwan Wu , Pravin L. Kotian , V. Satish Kumar , Tsu-Hsing Lin , Yahya El-Kattan , Ajit K. Ghosh
IPC分类号： A61K38/21 , C07H7/06 , A61K31/7068 , A61K31/7064 , A61K31/7088 , A61P31/12 , C12N9/12
CPC分类号： A61K31/7064 , A61K31/7056 , A61K31/7068 , A61K38/212 , A61K38/2292 , A61K45/06 , C07H7/06 , C07H11/04 , C07H19/22 , Y02A50/393 , Y02A50/465
摘要： The invention provides methods for treating hepatitis C viral infections and related viral infections, as well as compounds and compositions that are useful for treating such infections.
摘要翻译： 本发明提供了治疗丙型肝炎病毒感染和相关病毒感染的方法，以及可用于治疗这种感染的化合物和组合物。
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公开(公告)号：US07514410B2
公开(公告)日：2009-04-07
申请号：US11388060
申请日：2006-03-23
申请人： Yarlagadda S. Babu , Pooran Chand , Minwan Wu , Pravin L. Kotian , V. Satish Kumar , Tsu-Hsing Lin , Yahya El-Kattan , Ajit K. Ghosh
发明人： Yarlagadda S. Babu , Pooran Chand , Minwan Wu , Pravin L. Kotian , V. Satish Kumar , Tsu-Hsing Lin , Yahya El-Kattan , Ajit K. Ghosh
IPC分类号： A01N43/04
CPC分类号： A61K31/7064 , A61K31/7056 , A61K31/7068 , A61K38/212 , A61K38/2292 , A61K45/06 , C07H7/06 , C07H11/04 , C07H19/22 , Y02A50/393 , Y02A50/465
摘要： The invention provides methods for treating hepatitis C viral infections and related viral infections, as well as compounds and compositions that are useful for treating such infections.
摘要翻译： 本发明提供了治疗丙型肝炎病毒感染和相关病毒感染的方法，以及可用于治疗这种感染的化合物和组合物。
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公开(公告)号：US20130078218A1
公开(公告)日：2013-03-28
申请号：US13430341
申请日：2012-03-26
申请人： Yarlagadda S. Babu , Pooran Chand , Minwan Wu , Pravin L. Kotian , V. Satish Kumar , Tsu-Hsing Lin , Yahya El-Kattan , Ajit K. Ghosh
发明人： Yarlagadda S. Babu , Pooran Chand , Minwan Wu , Pravin L. Kotian , V. Satish Kumar , Tsu-Hsing Lin , Yahya El-Kattan , Ajit K. Ghosh
IPC分类号： A61K31/7064 , A61K31/7068 , A61K45/06 , A61K31/7056 , A61K38/22 , A61K38/21 , C07H7/06 , C07H11/04
CPC分类号： A61K31/7064 , A61K31/7056 , A61K31/7068 , A61K38/212 , A61K38/2292 , A61K45/06 , C07H7/06 , C07H11/04 , C07H19/22 , Y02A50/393 , Y02A50/465
摘要： The invention provides methods for treating hepatitis C viral infections and related viral infections, as well as compounds and compositions that are useful for treating such infections.
摘要翻译： 本发明提供了治疗丙型肝炎病毒感染和相关病毒感染的方法，以及可用于治疗这种感染的化合物和组合物。
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公开(公告)号：US08163703B2
公开(公告)日：2012-04-24
申请号：US12399521
申请日：2009-03-06
申请人： Yarlagadda S. Babu , Pooran Chand , Minwan Wu , Pravin L. Kotian , V. Satish Kumar , Tsu-Hsing Lin , Yahya El-Kattan , Ajit K. Ghosh
发明人： Yarlagadda S. Babu , Pooran Chand , Minwan Wu , Pravin L. Kotian , V. Satish Kumar , Tsu-Hsing Lin , Yahya El-Kattan , Ajit K. Ghosh
CPC分类号： A61K31/7064 , A61K31/7056 , A61K31/7068 , A61K38/212 , A61K38/2292 , A61K45/06 , C07H7/06 , C07H11/04 , C07H19/22 , Y02A50/393 , Y02A50/465
摘要： The invention provides methods for treating hepatitis C viral infections and related viral infections, as well as compounds and compositions that are useful for treating such infections.
摘要翻译： 本发明提供了治疗丙型肝炎病毒感染和相关病毒感染的方法，以及可用于治疗这种感染的化合物和组合物。
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公开(公告)号：US08133870B2
公开(公告)日：2012-03-13
申请号：US11666264
申请日：2005-10-28
申请人： Yarlagadda S. Babu , Pooran Chand , Minwan Wu , Pravin L. Kotian , V. Satish Kumar , Tsu-Hsing Lin , Yahya El-Kattan , Ajit K. Ghosh
发明人： Yarlagadda S. Babu , Pooran Chand , Minwan Wu , Pravin L. Kotian , V. Satish Kumar , Tsu-Hsing Lin , Yahya El-Kattan , Ajit K. Ghosh
CPC分类号： C07D495/04 , A61K31/675 , A61K31/7076 , A61K38/212 , A61K38/2292 , C07D491/048 , C07D493/04 , C07F9/6561 , C07H7/06 , C07H19/22 , Y02A50/393 , Y02A50/465 , A61K2300/00
摘要： The invention provides compounds of formula I, II, and III as described herein, as well as pharmaceutical compositions comprising the compounds, and synthetic methods and intermediates that are useful for preparing the compounds. The compounds of formula I, II, and III are useful as anti-viral agents and/or as anti-cancer agents.
摘要翻译： 本发明提供了本文所述的式I，II和III的化合物，以及包含该化合物的药物组合物，以及可用于制备化合物的合成方法和中间体。 式I，II和III的化合物可用作抗病毒剂和/或作为抗癌剂。
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