利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

227 条记录 (耗时 0.033 秒)

    Dissolution liquid for drug in iontophoresis
    1.
    发明授权
    Dissolution liquid for drug in iontophoresis 失效
    药物溶出液在离子电渗疗法中的应用

    公开(公告)号：US5993848A

    公开(公告)日：1999-11-30

    申请号：US659372

    申请日：1996-06-06

    申请人： Yasuyuki Suzuki ,  Katsumi Iga ,  Yukihiro Matsumoto

    发明人： Yasuyuki Suzuki ,  Katsumi Iga ,  Yukihiro Matsumoto

    IPC分类号： A61N1/30 ,  A61K31/785 ,  A61F13/00

    CPC分类号： A61N1/30

    摘要： A drug held or supported by an interface comprising a porous matrix is dissolved with a drug dissolution liquid containing a humectant, and the drug is transdermally delivered by iontophoresis. The humectant includes e.g. glycerin and other polyhydric alcohols, sugar alcohols, proline and other amino acids and acidic mucopolysaccharides. The concentration of the humectant may be about 1 to 50% by weight, and the concentration of proline or other amino acid or its salt may be about 1 to 30% by weight. The drug includes (1) a physiologically active peptide or protein with a molecular weight of 100 to 30,000 or (2) a nonpeptide physiologically active compound with a molecular weight of 100 to 1,000.

    摘要翻译： 由包含多孔基质的界面保持或负载的药物与含有保湿剂的药物溶解液溶解，并且通过离子电渗法透皮递送药物。 保湿剂包括例如 甘油等多元醇，糖醇，脯氨酸等氨基酸和酸性粘多糖。 保湿剂的浓度可以为约1至50重量％，脯氨酸或其它氨基酸或其盐的浓度可以为约1至30重量％。 药物包括（1）分子量为100〜30,000的生理活性肽或蛋白质，或（2）分子量为100〜1,000的非肽生理活性化合物。

    Matrix for iontophoreses
    2.
    发明授权
    Matrix for iontophoreses 失效
    离子电极矩阵

    公开(公告)号：US06416503B1

    公开(公告)日：2002-07-09

    申请号：US08842516

    申请日：1997-04-24

    申请人： Yasuyuki Suzuki ,  Katsumi Iga ,  Hiroaki Okada ,  Yukihiro Matsumoto

    发明人： Yasuyuki Suzuki ,  Katsumi Iga ,  Hiroaki Okada ,  Yukihiro Matsumoto

    IPC分类号： A61N130

    CPC分类号： A61N1/30

    摘要： To provide a practical matrix for iontophoresis with markedly improved drug availability. A system for iontophoreses, which comprises an anode side matrix and a cathode side matrix, wherein the anode side matrix contains a cationized drug and the cathode side matrix contains a water soluble acidic substance. A matrix for iontophoreses comprising a drug reservoir containing a drug, the drug reservoir having a thickness of less than 0.05 mm. Iontophoresis using the iontophoretic matrix of the present invention makes it possible to administer a drug to the body at high availability.

    摘要翻译： 为离子电渗提供实用的基质，显着改善了药物的可用性。 一种用于离子电极的系统，其包括阳极侧基质和阴极侧基质，其中阳极侧基质含有阳离子化药物，阴极侧基质含有水溶性酸性物质。 一种用于离子载体的基质，其包含含有药物的药物储存器，所述药物储存器的厚度小于0.05mm。 使用本发明的离子电渗基质的离子电渗疗法使得可以以高可用性将药物施用于身体。

    Dissolution liquid for drug in iontophoresis
    3.
    发明授权
    Dissolution liquid for drug in iontophoresis 有权
    药物溶出液在离子电渗疗法中的应用

    公开(公告)号：US06248349B1

    公开(公告)日：2001-06-19

    申请号：US09137744

    申请日：1998-08-21

    申请人： Yasuyuki Suzuki ,  Katsumi Iga ,  Yukihiro Matsumoto

    发明人： Yasuyuki Suzuki ,  Katsumi Iga ,  Yukihiro Matsumoto

    IPC分类号： A61K900

    CPC分类号： A61N1/30

    摘要： A drug held or supported by an interface comprising a porous matrix is dissolved with a drug dissolution liquid containing a humectant, and the drug is transdermally delivered by iontophoresis. The humectant includes e.g. glycerin and other polyhydric alcohols, sugar alcohols, proline and other amino acids and acidic mucopolysaccharides. The concentration of the humectant may be about 1 to 50% by weight, and the concentration of proline or other amino acid or its salt may be about 1 to 30% by weight. The drug includes (1) a physiologically active peptide or protein with a molecular weight of 100 to 30,000 or (2) a nonpeptide physiologically active compound with a molecular weight of 100 to 1,000.

    摘要翻译： 由包含多孔基质的界面保持或负载的药物与含有保湿剂的药物溶解液溶解，并且通过离子电渗法透皮递送药物。 保湿剂包括例如 甘油等多元醇，糖醇，脯氨酸等氨基酸和酸性粘多糖。 保湿剂的浓度可以为约1至50重量％，脯氨酸或其它氨基酸或其盐的浓度可以为约1至30重量％。 药物包括（1）分子量为100〜30,000的生理活性肽或蛋白质，或（2）分子量为100〜1,000的非肽生理活性化合物。

    Iontophoresis method
    6.
    发明授权
    Iontophoresis method 有权
    离子电渗法

    公开(公告)号：US06526316B2

    公开(公告)日：2003-02-25

    申请号：US09207605

    申请日：1998-12-09

    申请人： Katsumi Iga ,  Yasuyuki Suzuki ,  Masahiro Kawase

    发明人： Katsumi Iga ,  Yasuyuki Suzuki ,  Masahiro Kawase

    IPC分类号： A61N130

    CPC分类号： A61N1/0432 ,  A61N1/30 ,  A61N1/325

    摘要： A method for transdermal administration of parathyroid hormone by iontophoresis, which comprises applying electric current at least 2 times a day, which method is repeated one to four times each week, or an apparatus for the iontophoresis can be widely applied for not only the prevention or treatment of osteoporosis but also for general bone diseases which require promotion of bone morphogenesis, for example, treatment of ordinary fractures. The method of the present invention produces excellent pharmacological effects such as few side effects and a high bioavailability in long term administration for the prevention and treatment of bone diseases.

    摘要翻译： 通过离子电渗法透皮给药甲状旁腺激素的方法，其包括每天施加电流至少2次，该方法每周重复1-4次，或者用于离子电渗疗法的装置不仅可广泛应用于预防或 治疗骨质疏松症，而且对于需要促进骨形态发生的一般骨病，例如治疗普通骨折。本发明的方法产生优异的药理作用，例如在长期给药中的副作用少，生物利用度高，用于预防 并治疗骨病。

    SOUND GENERATING DEVICE FOR VEHICLE, AND SOUND GENERATING METHOD FOR VEHICLE
    8.
    发明申请
    SOUND GENERATING DEVICE FOR VEHICLE, AND SOUND GENERATING METHOD FOR VEHICLE 有权
    用于车辆的声音发生装置和用于车辆的声音发生方法

    公开(公告)号：US20130230185A1

    公开(公告)日：2013-09-05

    申请号：US13883614

    申请日：2012-04-16

    申请人： Hideki Osawa ,  Heiji Maruyama ,  Yasuyuki Suzuki ,  Yosuke Kuno ,  Hirofumi Onitsuka ,  Yoshikazu Honji

    发明人： Hideki Osawa ,  Heiji Maruyama ,  Yasuyuki Suzuki ,  Yosuke Kuno ,  Hirofumi Onitsuka ,  Yoshikazu Honji

    IPC分类号： B60Q5/00

    CPC分类号： B60Q5/00 ,  B60R11/0217 ,  F01N1/065 ,  F02M35/021 ,  F02M35/1038 ,  F02M35/1294 ,  G10K15/02

    摘要： Provided is a sound generating device (20) for a vehicle, including: a plurality of pressure sensors (21a to 21d) for detecting air pressures of an air intake sound of an engine (12) and outputting the air pressures as sound pressure signals; a signal processing unit (24) for performing processing of changing the sound pressure signals in accordance with a driving condition of a vehicle (10); and loudspeakers (28a and 28b) for outputting the sound pressure signals as the air intake sound of the engine (12). Then, the plurality of pressure sensors (21a to 21d) are provided at an interval in a circumferential direction of an outer periphery of an air intake duct (15) at positions in a vicinity of an air flow meter (18) on an air cleaner (16) side with respect to a center of the air intake duct (15), the air intake duct (15) connecting the air cleaner (16) to a throttle body (17).

    摘要翻译： 本发明提供一种用于车辆的发声装置（20），包括：多个用于检测发动机（12）的吸气声的空气压力并将空气压力作为声压信号输出的压力传感器（21a〜21d） 信号处理单元（24），用于根据车辆（10）的驾驶状况执行改变声压信号的处理; 以及用于输出作为发动机（12）的进气声音的声压信号的扬声器（28a和28b）。 然后，多个压力传感器（21a〜21d）在空气净化器（18）的空气流量计（18）附近的位置处，在进气管道（15）的外周的周向上隔开间隔设置 （16）相对于进气管道（15）的中心的空气吸入管道（15），将空气滤清器（16）连接到节气门体（17）的进气管道（15）。

    Method for stabilizing anti-dementia drug
    9.
    发明授权
    Method for stabilizing anti-dementia drug 有权

    公开(公告)号：US08481565B2

    公开(公告)日：2013-07-09

    申请号：US11793722

    申请日：2005-12-27

    申请人： Yosuke Ueki ,  Yasuyuki Suzuki ,  Satoshi Fujioka

    发明人： Yosuke Ueki ,  Yasuyuki Suzuki ,  Satoshi Fujioka

    IPC分类号： A01N43/42 ,  A61K9/14

    CPC分类号： A61K9/2054 ,  A61K9/1635 ,  A61K9/1652 ,  A61K9/2027 ,  A61K31/445

    摘要： The present invention provides a method for stabilizing an anti-dementia drug in a pharmaceutical composition containing the anti-dementia drug and a high molecular weight basic substance by adding a high molecular weight acidic substance to said pharmaceutical composition. Further, the present invention provides a pharmaceutical composition containing an anti-dementia drug and a high molecular basic substance in which a high molecular weight acidic substance is contained for stabilizing the anti-dementia drug. Furthermore, the present invention provides a method for manufacturing a pharmaceutical composition which comprises steps wherein a solution or suspension containing a high molecular weight acidic substance is added to a mixture of an anti-dementia drug and a high molecular weight basic substance for the sake of stabilizing the anti-dementia drug.

    COMMODITY SALES DATA PROCESSING APPARATUS AND CONTROL METHOD THEREOF
    10.
    发明申请
    COMMODITY SALES DATA PROCESSING APPARATUS AND CONTROL METHOD THEREOF 审中-公开
    商品销售数据处理装置及其控制方法

    公开(公告)号：US20120316977A1

    公开(公告)日：2012-12-13

    申请号：US13486271

    申请日：2012-06-01

    申请人： Yasuyuki Suzuki

    发明人： Yasuyuki Suzuki

    IPC分类号： G06Q20/20

    CPC分类号： G06Q20/20

    摘要： A commodity sales data processing apparatus receives input of a comprehension degree which indicates the comprehension degree of a customer purchasing the commodity whose explanation is required by a salesperson if the sales data of the commodity whose explained is required by the salesperson is input through an input unit, and stores an information indicating the comprehension degree received in association with an identification information of at least one of the commodity and the salesperson.

    摘要翻译： 商品销售数据处理装置接收输入的理解度，其指示如果销售人员所要求的商品的销售数据通过输入单元输入的，则销售人员需要解释的商品的购买商品的理解度的输入 并且存储指示与商品和销售员中的至少一个的识别信息相关联的表示理解度的信息。