公开(公告)号：US6011989A

公开(公告)日：2000-01-04

申请号：US129213

申请日：1998-08-05

申请人： Yoshihiro Sugo ,  Takeshi Sohma ,  Rie Tanaka ,  Wenxi Chen ,  Shigeru Aso ,  Ryoichi Ochiai

发明人： Yoshihiro Sugo ,  Takeshi Sohma ,  Rie Tanaka ,  Wenxi Chen ,  Shigeru Aso ,  Ryoichi Ochiai

IPC分类号： A61B5/00 ,  A61B5/0205 ,  A61B5/0468 ,  A61B5/0472 ,  A61B5/02

CPC分类号： A61B5/0468 ,  A61B5/0205 ,  A61B5/1455

摘要： An electrocardiogram signal derived from electrocardiogram measuring means 1 and a pulse signal derived from pulse-wave measuring means 2 are applied to a CPU 30. The CPU 30 processes the cardiogram signal to detect a QRS wave signal, and processes the pulse signal to detect the amplitude of the pulse signal. The CPU 30 judges whether or not the QRS wave is caused by a ventricular premature contraction. If two QRS waves, not caused by ventricular premature contraction, occurs successively, and the CPU 30 judges if A0.times.k>A1. The CPU 30 judges that a supraventricular extrasystole is occurred. Here, A0 is an amplitude of the first QSR wave; A1 is an amplitude of the second QSR wave; and k is a preset value, 0

摘要翻译： 将来自心电图测量装置1的心电图信号和从脉搏波测量装置2导出的脉冲信号施加到CPU 30.CPU30处理心电图信号以检测QRS波信号，并处理脉冲信号以检测 脉冲信号的幅度。 CPU30判断QRS波是否由心室过早收缩引起。 如果不是由心室过早收缩引起的两个QRS波连续发生，并且CPU 30判断A0xk> A1。 CPU30判断出发生室上性收缩期。 这里，A0是第一QSR波的振幅; A1是第二个QSR波的振幅; k是0

公开(公告)号：US06241682B1

公开(公告)日：2001-06-05

申请号：US09639232

申请日：2000-08-16

申请人： Ryoichi Ochiai ,  Yoshihiro Sugo ,  Takeshi Sohma ,  Rie Tanaka ,  Wenxi Chen

发明人： Ryoichi Ochiai ,  Yoshihiro Sugo ,  Takeshi Sohma ,  Rie Tanaka ,  Wenxi Chen

IPC分类号： A61B504

CPC分类号： A61B5/0452 ,  A61B5/022

摘要： A pacing-pulse detecting circuit 3 detects pacing pulses from an electrocardiogram signal led from an electrocardiogram electrode 1. A mode-status judging means 21 judges a mode status, a pacing mode or a nonpacing mode, on the basis of the pacing pulse detected. The detect result is transmitted to a CPU 5. The CPU 5 causes a display device 10 to display the result. An operator sees the display and operates a key 22, and gives an instruction to start a blood pressure measurement to the CPU 5. The CPU 5 drives a pump 13 and an exhaust valve 14 to supply and discharge air to and from a cuff 11, and measures a blood pressure by use of pressure data led from a pressure sensor 15.

摘要翻译： 起搏脉冲检测电路3根据从心电图电极1引出的心电图信号检测起搏脉冲。模式状态判断装置21基于检测到的起搏脉冲来判断模式状态，起搏模式或非起搏模式。 检测结果被发送到CPU 5.CPU5使显示装置10显示结果。 操作者看到显示器并操作键22，并给出了对CPU 5进行血压测量的指令.CPU5驱动泵13和排气阀14以向袖口11供给和排出空气， 并且通过使用从压力传感器15引导的压力数据来测量血压。

公开(公告)号：US6049731A

公开(公告)日：2000-04-11

申请号：US136964

申请日：1998-08-20

申请人： Ryoichi Ochiai ,  Yoshihiro Sugo ,  Takeshi Sohma ,  Rie Tanaka ,  Wenxi Chen

发明人： Ryoichi Ochiai ,  Yoshihiro Sugo ,  Takeshi Sohma ,  Rie Tanaka ,  Wenxi Chen

IPC分类号： A61B5/00 ,  A61B5/022 ,  A61B5/0402 ,  A61B5/0452

CPC分类号： A61B5/0452 ,  A61B5/022

摘要： A pacing-pulse detecting circuit 3 detects pacing pulses from an electrocardiogram signal led from an electrocardiogram electrode 1. A mode-status judging means 21 judges a mode status, a pacing mode or a nonpacing mode, on the basis of the pacing pulse detected. The detect result is transmitted to a CPU 5. The CPU causes a display device 10 to display the result. An operator sees the display and operates a key 22, and gives an instruction to start a blood pressure measurement to the CPU 5. The CPU 5 drives a pump 13 and an exhaust valve 14 to supply and discharge air to and from a cuff 11, and measures a blood pressure by use of pressure data led from a pressure sensor 15.

摘要翻译： 起搏脉冲检测电路3根据从心电图电极1引出的心电图信号检测起搏脉冲。模式状态判断装置21基于检测到的起搏脉冲来判断模式状态，起搏模式或非起搏模式。 检测结果被发送到CPU 5.CPU使显示装置10显示结果。 操作者看到显示器并操作键22，并给出了对CPU 5进行血压测量的指令.CPU5驱动泵13和排气阀14以向袖口11供给和排出空气， 并且通过使用从压力传感器15引导的压力数据来测量血压。

公开(公告)号：US6122543A

公开(公告)日：2000-09-19

申请号：US505664

申请日：2000-02-17

申请人： Ryoichi Ochiai ,  Yoshihiro Sugo ,  Takeshi Sohma ,  Rie Tanaka ,  Wenxi Chen

发明人： Ryoichi Ochiai ,  Yoshihiro Sugo ,  Takeshi Sohma ,  Rie Tanaka ,  Wenxi Chen

IPC分类号： A61B5/00 ,  A61B5/022 ,  A61B5/0402 ,  A61B5/0452 ,  A61B5/021

CPC分类号： A61B5/0452 ,  A61B5/022

摘要： A pacing-pulse detecting circuit 3 detects pacing pulses from an electrocardiogram signal led from an electrocardiogram electrode 1. A mode-status judging means 21 judges a mode status, a pacing mode or a nonpacing mode, on the basis of the pacing pulse detected. The detect result is transmitted to a CPU 5. The CPU 5 causes a display device 10 to display the result. An operator sees the display and operates a key 22, and gives an instruction to start a blood pressure measurement to the CPU 5. The CPU 5 drives a pump 13 and an exhaust valve 14 to supply and discharge air to and from a cuff 11, and measures a blood pressure by use of pressure data led from a pressure sensor 15.

摘要翻译： 起搏脉冲检测电路3根据从心电图电极1引出的心电图信号检测起搏脉冲。模式状态判断装置21基于检测到的起搏脉冲来判断模式状态，起搏模式或非起搏模式。 检测结果被发送到CPU 5.CPU5使显示装置10显示结果。 操作者看到显示器并操作键22，并给出了对CPU 5进行血压测量的指令.CPU5驱动泵13和排气阀14以向袖口11供给和排出空气， 并且通过使用从压力传感器15引导的压力数据来测量血压。

公开(公告)号：US6129677A

公开(公告)日：2000-10-10

申请号：US131678

申请日：1998-08-10

申请人： Takeshi Sohma ,  Yoshihiro Sugo ,  Rie Tanaka ,  Wenxi Chen ,  Hiromitsu Kasuya ,  Kohei Ono

发明人： Takeshi Sohma ,  Yoshihiro Sugo ,  Rie Tanaka ,  Wenxi Chen ,  Hiromitsu Kasuya ,  Kohei Ono

IPC分类号： A61B5/0245 ,  A61B5/0285 ,  G06F17/00 ,  A61B5/0452

CPC分类号： A61B5/0285

摘要： An apparatus for non-invasion heart monitoring includes electrocardiogram measuring means (1) for measuring electrocardiograms, pulse wave measuring means (2) for measuring pulse waves, and a CPU (30) for processing electrocardiogram signals derived from the electrocardiogram measuring means (1) and pulse wave signals derived from the pulse-wave measuring means (2). The CPU (30) detects the amplitudes of the pulse waves corresponding to the R waves of the cardiogram and the pulse wave propagation times, and computes a ratio (Nr/N) of the heart rate N and the heart rate Nr exclusive of the heart beats of wave deficits.

摘要翻译： 一种用于非入侵心脏监测的装置包括用于测量心电图的心电图测量装置（1），用于测量脉搏波的脉搏波测量装置（2）和用于处理从心电图测量装置（1）得到的心电图信号的CPU（30） 和从脉波测量装置（2）导出的脉波信号。 CPU（30）检测与心电图的R波和脉波传播时间相对应的脉搏波的振幅，并计算出心脏N的比值（Nr / N）和排除心脏的心率Nr 波浪失败。

公开(公告)号：US5755669A

公开(公告)日：1998-05-26

申请号：US841684

申请日：1997-04-30

申请人： Kohei Ono ,  Hiromitsu Kasuya ,  Yoshihiro Sugo ,  Takeshi Sohma ,  Wenxi Chen

发明人： Kohei Ono ,  Hiromitsu Kasuya ,  Yoshihiro Sugo ,  Takeshi Sohma ,  Wenxi Chen

IPC分类号： A61B5/0225 ,  A61B5/0285 ,  A61B5/00

CPC分类号： A61B5/02125 ,  A61B5/02255 ,  A61B5/0285

摘要： After an initial blood pressure measurement using a cuff 2 has been made, not only a pulse wave propagation time Tt is counted consecutively, but also a pulse wave propagation time change .DELTA.T is calculated every time the pulse wave propagation time Tt is counted and compared with a pulse wave propagation change threshold .DELTA.Ts. When the pulse wave propagation time change .DELTA.T exceeds the pulse wave propagation time change threshold .DELTA.Ts, not only a blood pressure value BPt is measured with the cuff 2, but also a pulse wave propagation time Tt.sub.1 is counted. If there are at least two sets of data, each set of data consisting of a blood pressure value BPt and a pulse wave propagation time Tt.sub.1, coefficients .alpha., .beta. specific to a subject are calculated from such two sets of data by a least-squares method. Then, the pulse wave propagation time change threshold .DELTA.Ts is calculated from the coefficient .alpha., and the current pulse wave propagation time change threshold .DELTA.Ts is updated.

摘要翻译： 在进行了使用袖带2的初始血压测定之后，不仅脉冲波传播时间Tt连续计数，而且每当脉搏波传播时间Tt被计数并进行比较时也计算出脉搏波传播时间变化量DELTA T 具有脉波传播变化阈值DELTA Ts。 当脉波传播时间变化DELTA T超过脉波传播时间变化阈值DELTA Ts时，不仅用袖带2测定血压值BPt，而且对脉搏波传播时间Tt1进行计数。 如果存在至少两组数据，则由血压值BPt和脉搏波传播时间Tt1组成的每组数据由特定于对象的这两组数据通过最小二乘法计算 方法。 然后，根据系数α计算脉波传播时间变化阈值DELTA Ts，并且更新当前脉搏波传播时间变化阈值DELTA Ts。

公开(公告)号：US5876348A

公开(公告)日：1999-03-02

申请号：US993562

申请日：1997-12-18

申请人： Yoshihiro Sugo ,  Takeshi Sohma ,  Hiromitsu Kasuya ,  Rie Tanaka

发明人： Yoshihiro Sugo ,  Takeshi Sohma ,  Hiromitsu Kasuya ,  Rie Tanaka

IPC分类号： A61B5/022 ,  A61B5/0245 ,  A61B5/0285 ,  A61B5/0456 ,  A61B5/02

CPC分类号： A61B5/02125 ,  A61B5/022 ,  A61B5/0285 ,  A61B5/0456

摘要： During a noninvasive blood pressure measurement using a cuff 2, a pulse wave propagation time T1 from the appearance of the peak value of an R wave in an electrocardiogram (ECG) waveform to the appearance of the bottom value of a pulse wave is counted, and a blood pressure value BP1 is calculated from a count result T1 and parameters .alpha., .beta. specific to a subject obtained during a pulse wave propagation time calibration. Then, the absolute value of a difference between the blood pressure value BP1 and a blood pressure value NIBP1 obtained by the noninvasive blood pressure measurement using the cuff 2 is calculated, and it is indeed whether or not the calculated absolute value is within a predetermined threshold.sub.-- BP. If the absolute value is judged to exceed the threshold.sub.-- BP, then blood pressure is measured again noninvasively using the cuff 2, and a blood pressure value NIBP1'obtained from such repeated measurement is displayed on a display 22.

摘要翻译： 在使用袖带2的无创血压测定中，计数从心电图（ECG）波形中的R波的峰值出现到脉搏波的底部值的出现的脉搏波传播时间T1， 根据计数结果T1和在脉搏波传播时间校准期间获得的对象特有的参数α，β计算血压值BP1。 然后，计算通过使用袖带2的无创血压测定得到的血压值BP1与血压值NIBP1之差的绝对值，实际上是否计算出的绝对值在规定的阈值以内 -BP。 如果绝对值被判断为超过阈值-BP，则使用袖带2再次非侵入性地测量血压，并且在显示器22上显示从这种重复测量获得的血压值NIBP1。

公开(公告)号：US5709212A

公开(公告)日：1998-01-20

申请号：US413223

申请日：1995-03-30

申请人： Yoshihiro Sugo ,  Takeshi Sohma

发明人： Yoshihiro Sugo ,  Takeshi Sohma

IPC分类号： A61B5/022 ,  G06F17/00 ,  A61B5/00

CPC分类号： A61B5/021 ,  A61B5/02125 ,  A61B5/0456

摘要： A blood pressure measuring device includes: a memory for storing a standard constant .alpha.; an input means for inputting a correcting blood pressure value; a time interval reference point detection section for detecting a time interval detection reference point in a pulse wave on the side of aortae; a pulse wave detection section for detecting a pulse wave on the side of peripheral blood vessels appearing with a time lag with respect to the pulse wave on the side of aortae; a pulse wave propagation time measurement section for measuring a pulse wave propagation time based on respective detected outputs from the time interval detection reference point detection means and the pulse wave detection means; an operation means for determining a constant .beta. using the blood pressure value for calibration, pulse wave propagation time, and standard constant .alpha. inputted for calibration; an operation means for calculating the blood pressure value from the pulse wave propagation time measured at a predetermined time interval for measuring a circadian blood pressure fluctuation, and the standard constants .alpha., .beta.; a memory for consecutively storing the measured pulse wave propagation time and the blood pressure value calculated from the pulse wave propagation time; and an external output connector for outputting at least the blood pressure value and pulse wave propagation time data as a result of the circadian blood pressure fluctuation measurement.

摘要翻译： 血压测量装置包括：用于存储标准常数α的存储器; 用于输入校正血压值的输入装置; 时间间隔参考点检测部分，用于检测大脑侧脉搏波中的时间间隔检测参考点; 脉搏波检测部，用于检测出现在相对于主动脉一侧的脉搏波的时滞的外周血管侧的脉搏波; 脉搏波传播时间测定部，其根据来自所述时间间隔检测基准点检测单元和所述脉波检测单元的各检测输出来测定脉波传播时间; 使用用于校准的血压值，脉搏波传播时间和用于校准的标准常数α来确定恒定值β的操作装置; 从用于测量昼夜血压波动的预定时间间隔测量的脉搏波传播时间和标准常数α，β计算血压值的操作装置; 用于连续存储由脉搏波传播时间计算出的测量脉搏波传播时间和血压值的存储器; 以及作为昼夜血压波动测量的结果，至少输出血压值和脉搏波传播时间数据的外部输出连接器。

公开(公告)号：US6083171A

公开(公告)日：2000-07-04

申请号：US742750

申请日：1996-11-01

申请人： Kohei Ono ,  Hiromitsu Kasuya ,  Yoshihiro Sugo ,  Takeshi Sohma ,  Hidehiro Hosaka

发明人： Kohei Ono ,  Hiromitsu Kasuya ,  Yoshihiro Sugo ,  Takeshi Sohma ,  Hidehiro Hosaka

IPC分类号： A61B5/022 ,  A61B5/0285 ,  A61B5/00

CPC分类号： A61B5/022 ,  A61B5/0285

摘要： A pulse wave propagation time is counted constantly. Not only it is judged whether or not a pulse wave propagation time change .DELTA.T exceeds a pulse wave propagation time change threshold .DELTA.Ts, but also it is judged whether or not cardiovascular dynamic changes .DELTA.HR, r.sub.1, r.sub.2 exceed thresholds thereof .DELTA.HRs, r.sub.1 s, r.sub.2 s, whereby a sudden turn for the worse in the blood pressure fluctuation of a subject is monitored. If any one of the changes exceeds the threshold thereof, a blood pressure measurement using a cuff 2 is made on the subject.

摘要翻译： 不断对脉搏波传播时间进行计数。 不仅判断脉波传播时间变化DELTA T是否超过脉波传播时间变化阈值DELTA Ts，而且判断心血管动态变化DELTA HR，r1，r2是否超过阈值DELTA HR， r1s，r2s，从而监测受试者的血压波动的突然转动。 如果任何一个变化超过其阈值，则对被检体进行使用袖带2的血压测量。

公开(公告)号：US5649543A

公开(公告)日：1997-07-22

申请号：US466746

申请日：1995-06-06

申请人： Hidehiro Hosaka ,  Hiroshi Sakata ,  Yoshihiro Sugo ,  Takeshi Sohma ,  Hiromitsu Kasuya

发明人： Hidehiro Hosaka ,  Hiroshi Sakata ,  Yoshihiro Sugo ,  Takeshi Sohma ,  Hiromitsu Kasuya

IPC分类号： A61B5/0205 ,  A61B5/022 ,  A61B5/0225 ,  A61B5/0285 ,  A61B5/00

CPC分类号： A61B5/0285 ,  A61B5/02255

摘要： A pulse-wave propagation time basis blood pressure monitor includes a memory for storing an equation describing the relationship between the pulse wave propagation time and the parameter .alpha., input means for entering the blood pressure value for calibration, a time-interval detect reference point detecting means for detecting a reference point for detecting the time interval of a pulse wave in the aorta of a subject; pulse wave detecting means for detecting a pulse wave which appears in the peripheral blood vessel after it appears in the aorta; pulse-wave propagation time measuring section for measuring a pulse wave propagation time from the output signals of the time-interval detect reference point detecting means and the pulse wave detecting means, first computing means for determining the parameter .alpha. proper to the subject on the basis of the general equation stored in the memory by using the pulse wave propagation time for calibration gathered from the subject, second computing means for determining the parameter .beta. to be added in computing a blood pressure value by using the pulse wave propagation time, by using the blood pressure value inputted for calibration, the pulse wave propagation time measured for calibration, and the parameter .alpha. determined by the first computing means, third computing means for computing a blood pressure value by using the measured pulse wave propagation time, and the parameters .alpha. and .beta., and measured data output means for outputting data of the computed blood pressure value.

摘要翻译： 脉搏波传播时间基准血压监视器包括用于存储描述脉搏波传播时间和参数α之间的关系的方程式的存储器，用于输入用于校准的血压值的输入装置，时间间隔检测参考点检测 用于检测用于检测被检体的主动脉中的脉搏波的时间间隔的参考点的装置; 脉波检测装置，用于检测外周血管出现在主动脉中后出现的脉搏波; 用于根据时间间隔检测基准点检测装置和脉搏波检测装置的输出信号测量脉搏波传播时间的脉波传播时间测量部分，第一计算装置，用于在此基础上确定对象的参数α 通过使用从对象收集的校准的脉搏波传播时间存储在存储器中的一般方程式的第二计算装置，用于通过使用脉波传播时间来确定计算血压值时要添加的参数β的第二计算装置， 用于校准输入的血压值，用于校准的脉搏波传播时间和由第一计算装置确定的参数α，第三计算装置，用于通过使用测量的脉搏波传播时间计算血压值，以及参数α和 β和用于输出计算出的血压值的数据的测量数据输出装置。