公开(公告)号：US20110022326A1

公开(公告)日：2011-01-27

申请号：US12787712

申请日：2010-05-26

申请人： Yoshiya ODA ,  Yasushi Ishihama ,  Tsuyoshi Tabata

发明人： Yoshiya ODA ,  Yasushi Ishihama ,  Tsuyoshi Tabata

IPC分类号： G06F19/00 ,  C12N5/07 ,  C12Q1/02 ,  C07C229/08

CPC分类号： G01N33/6848 ,  Y10T436/10 ,  Y10T436/104165 ,  Y10T436/104998 ,  Y10T436/105831 ,  Y10T436/24

摘要： Problem: An object of the present invention is to quantitate with good accuracy, furthermore, quantitate absolutely, one or a plurality of biological molecules in a sample such as a tissue, a biological fluid, a cell, a cell organ or protein complex.Solution: By adding a metabolically isotope labeled biological molecule as an internal standard substance and measuring with a mass spectrometer, quantitating with good accuracy one or a plurality of target molecules in a sample has become possible. In addition, by performing waveform separation processing during mass analysis, a highly accurate quantitative analysis method of mass analysis is provided.

摘要翻译： 问题：本发明的目的是准确定量，此外，在样品如组织，生物流体，细胞，细胞器官或蛋白质复合物中绝对地定量分析一种或多种生物分子。 解决方案：通过添加代谢同位素标记的生物分子作为内标物质并用质谱仪进行测量，以高精度定量，样品中的一个或多个目标分子成为可能。 此外，通过在质量分析中进行波形分离处理，提供了高精度的质量分析的定量分析方法。

公开(公告)号：US07759130B2

公开(公告)日：2010-07-20

申请号：US10579780

申请日：2004-11-22

申请人： Yoshiya Oda ,  Yasushi Ishihama ,  Tsuyoshi Tabata

发明人： Yoshiya Oda ,  Yasushi Ishihama ,  Tsuyoshi Tabata

IPC分类号： G01N24/00

CPC分类号： G01N33/6848 ,  Y10T436/10 ,  Y10T436/104165 ,  Y10T436/104998 ,  Y10T436/105831 ,  Y10T436/24

摘要： An object of the present invention is to quantitate with good accuracy, furthermore, quantitate absolutely, one or a plurality of biological molecules in a sample such as a tissue, a biological fluid, a cell, a cell organ or protein complex.By adding a metabolically isotope labeled biological molecule as an internal standard substance and measuring with a mass spectrometer, quantitating with good accuracy one or a plurality of target molecules in a sample has become possible. In addition, by performing waveform separation processing during mass analysis, a highly accurate quantitative analysis method of mass analysis is provided.

摘要翻译： 本发明的目的是准确定量，另外，在样品如组织，生物流体，细胞，细胞器官或蛋白质复合物中绝对地定量分析一种或多种生物分子。 通过添加代谢同位素标记的生物分子作为内标物质并用质谱仪进行测量，以高精度定量，样品中的一个或多个靶分子已成为可能。 此外，通过在质量分析中进行波形分离处理，提供了高精度的质量分析的定量分析方法。

公开(公告)号：US20070134806A1

公开(公告)日：2007-06-14

申请号：US10579780

申请日：2004-11-22

申请人： Yoshiya Oda ,  Yasushi Ishihama ,  Tsuyoshi Tabata

发明人： Yoshiya Oda ,  Yasushi Ishihama ,  Tsuyoshi Tabata

IPC分类号： G01N24/00

CPC分类号： G01N33/6848 ,  Y10T436/10 ,  Y10T436/104165 ,  Y10T436/104998 ,  Y10T436/105831 ,  Y10T436/24

摘要： Problem: An object of the present invention is to quantitate with good accuracy, furthermore, quantitate absolutely, one or a plurality of biological molecules in a sample such as a tissue, a biological fluid, a cell, a cell organ or protein complex. Solution: By adding a metabolically isotope labeled biological molecule as an internal standard substance and measuring with a mass spectrometer, quantitating with good accuracy one or a plurality of target molecules in a sample has become possible. In addition, by performing waveform separation processing during mass analysis, a highly accurate quantitative analysis method of mass analysis is provided.

摘要翻译： 问题：本发明的目的是准确定量，此外，在样品如组织，生物流体，细胞，细胞器官或蛋白质复合物中绝对地定量分析一种或多种生物分子。 解决方案：通过添加代谢同位素标记的生物分子作为内标物质并用质谱仪进行测量，以高精度定量，样品中的一个或多个目标分子成为可能。 此外，通过在质量分析中进行波形分离处理，提供了高精度的质量分析的定量分析方法。

公开(公告)号：US08131479B2

公开(公告)日：2012-03-06

申请号：US11630927

申请日：2005-07-04

申请人： Yoshiya Oda ,  Tsuyoshi Tabata

发明人： Yoshiya Oda ,  Tsuyoshi Tabata

IPC分类号： G06F19/00 ,  G01R23/02

CPC分类号： G01N33/6842 ,  B01J20/286 ,  B01J2220/54 ,  C07K1/22 ,  G01N30/8675 ,  G01N33/6848

摘要： A method for detecting plural types of phosphorylated proteins in a sample, wherein a database consisting of data regarding plural types of proteins in the sample is used; and a method for purifying phosphorylated proteins using an immobilized metal carrier or a titania carrier, wherein a solution containing acetonitrile in a range of 40% (v/v) or greater but 60% (v/v) or less is used.

摘要翻译： 一种用于检测样品中多种磷酸化蛋白质的方法，其中使用由样本中关于多种蛋白质的数据组成的数据库; 以及使用固定金属载体或二氧化钛载体来纯化磷酸化蛋白质的方法，其中使用含有40％（v / v）以上且60％（v / v）以下范围内的乙腈的溶液。

公开(公告)号：US20080221802A1

公开(公告)日：2008-09-11

申请号：US11630927

申请日：2005-07-04

申请人： Yoshiya Oda ,  Tsuyoshi Tabata

发明人： Yoshiya Oda ,  Tsuyoshi Tabata

IPC分类号： G01N33/68 ,  C07K1/14

CPC分类号： G01N33/6842 ,  B01J20/286 ,  B01J2220/54 ,  C07K1/22 ,  G01N30/8675 ,  G01N33/6848

摘要： A method for detecting plural types of phosphorylated proteins in a sample, wherein a database consisting of data regarding plural types of proteins in the sample is used; and a method for purifying phosphorylated proteins using an immobilized metal carrier or a titania carrier, wherein a solution containing acetonitrile in a range of 40% (v/v) or greater but 60% (v/v) or less is used.

摘要翻译： 一种用于检测样品中多种磷酸化蛋白质的方法，其中使用由样本中关于多种蛋白质的数据组成的数据库; 以及使用固定金属载体或二氧化钛载体来纯化磷酸化蛋白质的方法，其中使用含有40％（v / v）以上且60％（v / v）以下范围内的乙腈的溶液。

公开(公告)号：US20070202638A1

公开(公告)日：2007-08-30

申请号：US11790130

申请日：2007-04-24

申请人： Tsuyoshi Tabata ,  Kazuo Nakazato ,  Hiroshi Kujirai ,  Masahiro Moniwa ,  Hideyuki Matsuoka ,  Teruaki Kisu ,  Teruo Kisu ,  Haruko Kisu ,  Satoru Haga

发明人： Tsuyoshi Tabata ,  Kazuo Nakazato ,  Hiroshi Kujirai ,  Masahiro Moniwa ,  Hideyuki Matsuoka ,  Teruaki Kisu ,  Teruo Kisu ,  Haruko Kisu ,  Satoru Haga

IPC分类号： H01L21/84

CPC分类号： H01L27/10864 ,  H01L27/10867 ,  H01L27/10876 ,  Y10S257/903

摘要： A semiconductor memory device includes a vertical MISFET having a source region, a channel forming region, a drain region, and a gate electrode formed on a sidewall of the channel forming region via a gate insulating film. In manufacturing the semiconductor memory device, the vertical MISFET in which leakage current (off current) is less can be realized by: counter-doping boron of a conductivity type opposite to that of phosphorus diffused into a poly-crystalline silicon film (10) constituting the channel forming region from an n type poly-crystalline silicon film (7) constituting the source region of the vertical MISFET, and the above-mentioned poly-crystalline silicon film (10); and reducing an effective impurity concentration in the poly-crystalline silicon film (10).

摘要翻译： 半导体存储器件包括具有源极区，沟道形成区，漏极区和形成在沟道形成区的侧壁上的栅极的垂直MISFET，栅极绝缘膜。 在制造半导体存储器件时，可以通过以下方式实现泄漏电流（截止电流）较小的垂直MISFET：将与扩散到构成的多晶硅膜（10）的磷相反的导电类型的反向掺杂硼 来自构成垂直MISFET的源极区域的n型多晶硅膜（7）的沟道形成区域和上述多晶硅膜（10）; 并降低多晶硅膜（10）中的有效杂质浓度。

公开(公告)号：US09610875B2

公开(公告)日：2017-04-04

申请号：US13969943

申请日：2013-08-19

申请人： Tsuyoshi Tabata

发明人： Tsuyoshi Tabata

IPC分类号： A47C7/02 ,  B60N2/58 ,  B68G7/05 ,  D05B11/00 ,  B60N2/48 ,  B60N2/70

CPC分类号： B60N2/5883 ,  B60N2/5891 ,  B60N2/70 ,  B60N2/80 ,  B68G7/05 ,  D05B11/00 ,  Y10T29/481

摘要： A trim cover assembly of extremely soft property comprises a surface cover element, a wadding cover, and a thick foam wadding sandwiched therebetween, wherein the thick foam wadding has a compressed thin end surface region sewn with the surface cover element and wadding cover. Sewing method for forming such trim cover assembly involves: pressing and collapsing an end surface of the thick foam wadding in downwardly slantwise direction to provide a compressed thin area, thereby allowing direct access thereto of a conventional sewing machine; operating the sewing machine to sew the compressed thin area with the surface cover element, thereby producing a sewn trim cover having a compressed thin end region therein; and thereafter sewing the wadding cover with such sewn trim cover in correspondence with the compressed thin end region. As such, a trim cover assembly having the thick foam wadding is easily formed by the conventional sewing machine.

公开(公告)号：US09290119B2

公开(公告)日：2016-03-22

申请号：US14656836

申请日：2015-03-13

申请人： Tsuyoshi Tabata

发明人： Tsuyoshi Tabata

IPC分类号： B60N2/58 ,  B68G7/05 ,  D05B11/00 ,  B60N2/48 ,  B60N2/70

CPC分类号： B60N2/5883 ,  B60N2/5891 ,  B60N2/70 ,  B60N2/80 ,  B68G7/05 ,  D05B11/00 ,  Y10T29/481

摘要： A trim cover assembly of extremely soft property comprises a surface cover element, a wadding cover, and a thick foam wadding sandwiched therebetween, wherein the thick foam wadding has a compressed thin end surface region sewn with the surface cover element and wadding cover. Sewing method for forming such trim cover assembly involves: pressing and collapsing an end surface of the thick foam wadding in downwardly slantwise direction to provide a compressed thin area, thereby allowing direct access thereto of a conventional sewing machine; operating the sewing machine to sew the compressed thin area with the surface cover element, thereby producing a sewn trim cover having a compressed thin end region therein; and thereafter sewing the wadding cover with such sewn trim cover in correspondence with the compressed thin end region. As such, a trim cover assembly having the thick foam wadding is easily formed by the conventional sewing machine.

摘要翻译： 具有极其柔软性的装饰罩组件包括表面覆盖元件，填充盖和夹在其间的厚泡沫填料，其中厚泡沫填料具有缝合有表面覆盖元件和填塞盖的压缩薄端表面区域。 用于形成这种装饰罩组件的缝合方法包括：将厚泡沫的端面向下倾斜压缩并塌缩以提供压缩的薄区域，从而允许直接进入常规缝纫机; 操作缝纫机以与表面覆盖元件缝合压缩的薄区域，从而产生在其中具有压缩的薄端区域的缝合装饰罩; 然后对应于压缩的薄端区域，用这种缝合装饰罩缝合填料盖。 因此，通过常规缝纫机容易地形成具有厚泡沫填料的装饰罩组件。

公开(公告)号：US20080145474A1

公开(公告)日：2008-06-19

申请号：US11640299

申请日：2006-12-18

申请人： Tsuyoshi Tabata

发明人： Tsuyoshi Tabata

IPC分类号： B29C45/03

CPC分类号： B29C33/12 ,  B29C44/1271 ,  B29L2031/3026 ,  B60N2/7017 ,  B60N2/753

摘要： A foaming die device is provided, in which can be directly placed a basic armrest unit having a shaft element and a connecting bracket rotatably secured to the shaft element. The foaming die device comprises a lower die, an upper die, and an auxiliary die element of split type to be incorporated in a working die area defined by the lower and upper dies. The auxiliary die element comprises two die pieces that can be mated together so as to be in a slidable engagement about one end portion of the shaft element. Hence, the mated two die pieces or auxiliary die element is slidable along the shaft element for its partial engagement in a through-hole of the basic armrest unit, whereupon all the basic armrest unit and auxiliary die element may be directly placed in the working die area of lower and upper dies and subjected to foaming process.

摘要翻译： 提供了一种发泡模具装置，其中可以直接放置具有轴元件和可旋转地固定到轴元件的连接支架的基本扶手单元。 发泡模具装置包括下模具，上模具和分模型的辅助模具元件，以被并入由下模具和上模具限定的工作模具区域中。 辅助模具元件包括两个模子片，其可以配合在一起，以便在轴元件的一个端部处可滑动地接合。 因此，配合的两个模具或辅助模具元件可以沿着轴元件滑动以便部分地接合在基本扶手单元的通孔中，于是所有的基本扶手单元和辅助模具元件可以直接放置在工作模具中 下模和上模的区域，并进行发泡处理。

公开(公告)号：US07338129B2

公开(公告)日：2008-03-04

申请号：US11603907

申请日：2006-11-24

申请人： Tsuyoshi Tabata

发明人： Tsuyoshi Tabata

IPC分类号： A47C7/36

CPC分类号： B60N2/70 ,  B60N2/80

摘要： A foamed product integral with trim cover assembly, of the type having a frame element provide therein, with two local portions of the frame element projecting outwardly therefrom. The trim cover assembly used has two extensions, with an opening defined therebetween. Both two extensions are bent to and juxtaposed on one cover material portion thereof, thereby forming a three-layer portion therein. The three-layer portion is sewn so as to define an unsewed region therein. The unsewed region has two spaced-part through-holes formed therethrough, hence providing two spaced-apart continuous through-hoes. The two local portions of frame element are inserted through the respective two spaced-apart continuous through-holes, so that the unsewed region is stretched horizontally to keep the corresponding portions of the juxtaposed two extensions and cover material portion in close contact with one another.

摘要翻译： 与装饰罩组件一体的泡沫产品，其中具有框架元件的类型，框架元件的两个局部部分从其向外突出。 使用的装饰罩组件具有两个延伸部，其间形成有开口。 两个延伸部弯曲并且并置在其一个覆盖材料部分上，从而在其中形成三层部分。 缝合三层部分以便在其中限定未被覆盖的区域。 未被覆盖的区域具有穿过其形成的两个间隔开的通孔，因此提供两个间隔开的连续通孔。 框架元件的两个局部部分通过相应的两个间隔开的连续通孔插入，使得未被覆盖的区域被水平地拉伸以保持并置的两个延伸部分和覆盖材料部分的相应部分彼此紧密接触。