Monocotyledon plant indications extract compositions, method of preparation and pharmaceutical compositions containing them
    8.
    发明申请
    Monocotyledon plant indications extract compositions, method of preparation and pharmaceutical compositions containing them 审中-公开
    单子叶植物适应症提取物组合物,制备方法和含有它们的药物组合物

    公开(公告)号:US20080089957A1

    公开(公告)日:2008-04-17

    申请号:US11545442

    申请日:2006-10-11

    IPC分类号: A61K36/899 A61K36/88

    摘要: The present invention relates to a method for immuno-modulation in an organism by using a protein extract from a monocotyledon plant. The present invention also relates to a method for inhibiting nitrite production or anti-oxidation activity in an organism by using an organic extract from a monocotyledon plant. The present invention also relates to a method for regulating uric acid in an organism by using 6-aminopurine analogues.

    摘要翻译: 本发明涉及通过使用单子叶植物的蛋白质提取物在生物体中进行免疫调节的方法。 本发明还涉及通过使用来自单子叶植物的有机提取物来抑制生物体中的亚硝酸盐产生或抗氧化活性的方法。 本发明还涉及通过使用6-氨基嘌呤类似物来调节生物体中尿酸的方法。

    Anti liver disease drug R-YEEE and method of synthesizing branched galactose-terminal glycoproteins
    10.
    发明授权
    Anti liver disease drug R-YEEE and method of synthesizing branched galactose-terminal glycoproteins 有权
    抗肝病药物R-YEEE及合成支链半乳糖末端糖蛋白的方法

    公开(公告)号:US06383812B1

    公开(公告)日:2002-05-07

    申请号:US09490734

    申请日:2000-01-25

    IPC分类号: C12N1509

    CPC分类号: C07H15/18

    摘要: The present invention provides a novel method of synthesizing branched galactose-terminal glycoproteins. A number of these glycoproteins have binding affinity to the asialoglycoprotein receptor. The present invention also provides novel conjugates having branched galactose-terminal glycoproteins that is complexed to a therapeutically effective agent, such as an isolated protein, polysacharides, lipids and radioactive isotope. These conjugates may be used to deliver the therapeutically effective agent to mammalian cells generally, and to hepatocytes specifically.

    摘要翻译: 本发明提供了一种合成支链半乳糖末端糖蛋白的新方法。 许多这些糖蛋白与脱唾液酸糖蛋白受体具有结合亲和力。 本发明还提供了具有与治疗有效药物如分离的蛋白质,多糖,脂质和放射性同位素复合的支链半乳糖末端糖蛋白的新缀合物。 这些缀合物可以用于将治疗有效的药剂一般递送到哺乳动物细胞,特别是向肝细胞递送。