-
1.发明授权Control of magnetic film grain structure by modifying Ni-P plating of the substrate 失效通过改变衬底的Ni-P镀层来控制磁性膜晶粒结构公开(公告)号：US06524724B1
公开(公告)日：2003-02-25
申请号：US09779484
申请日：2001-02-09
申请人： Yuanda Randy Cheng , Connie Chunling Liu , Chung Shih , Linda Lijun Zhong , Jeff Duane St. John , Jeffery Lee Petrehn
发明人： Yuanda Randy Cheng , Connie Chunling Liu , Chung Shih , Linda Lijun Zhong , Jeff Duane St. John , Jeffery Lee Petrehn
IPC分类号： G11B566
CPC分类号： G11B5/7325 , C23C18/50 , C23C28/321 , C23C28/324 , C23C28/345 , G11B5/656 , Y10S428/90 , Y10T428/12465 , Y10T428/12854 , Y10T428/265
摘要： High areal density magnetic recording media exhibiting low noise are formed with a Ni—P—X plating layer, in which X is an additive meeting the following requirement: (1) The additive has a higher oxidation potential than that of Ni so that grains of an additive-rich-oxide will form first during oxidation under a controlled atmosphere and grains of a Ni-rich-oxide, if any, will form subsequently and separately from the grains of the additive-rich oxide. (2) The additive has a tendency to segregate to the top surface. (3) The additive is not a catalyst poison for Ni—P plating in the composition range.
摘要翻译： 使用Ni-PX镀层形成表现出低噪声的高密度磁记录介质，其中X是满足以下要求的添加剂：（1）添加剂具有比Ni更高的氧化电位，使添加剂的晶粒 在受控气氛下的氧化期间首先形成富氧氧化物，并且富含氧化物的晶粒（如果有的话）将随后和分开地与富含添加剂的氧化物的晶粒形成。 （2）添加剂倾向于分离到顶面。 （3）添加剂在组成范围内不是Ni-P镀层的催化剂毒物。
-
公开(公告)号：US20090075962A1
公开(公告)日：2009-03-19
申请号：US12277974
申请日：2008-11-25
IPC分类号： A61K31/565 , A61K31/365
CPC分类号： A61K9/0024 , A61K31/365 , A61K31/568 , A61K45/06 , A61K2300/00
摘要： An improved weight and growth stimulant for domesticated animals such as cattle, pigs and sheep is comprised of an anabolic agent that is subcutaneously administered in the form of a dual release implant formulation. Increased gains are particularly improved when zeranol is administered in an immediate-release and controlled-release formulation which allows for a one-time dosage injection.
-
公开(公告)号：US20070202363A1
公开(公告)日：2007-08-30
申请号：US11361004
申请日：2006-02-24
申请人： Erol Girt , Chung Shih , Miaogen Lu , Kueir-Weei Chour , Connie Liu , Mariana Munteanu , Jean Lee
发明人： Erol Girt , Chung Shih , Miaogen Lu , Kueir-Weei Chour , Connie Liu , Mariana Munteanu , Jean Lee
IPC分类号： G11B5/66
摘要： A magnetic recording medium having a Au, Ag-containing magnetic layer having Co, Cr, Ag and Au; the magnetic recording layer having Co-containing magnetic grains surrounded by substantially nonmagnetic Cr-containing grain boundaries; wherein said Ag and said Au are substantially immiscible in the Co-containing magnetic grains is disclosed.
摘要翻译： 具有含有Co，Cr，Ag和Au的Au，含Ag的磁性层的磁记录介质; 所述磁记录层具有由基本上非磁性的含Cr晶界包围的含Co磁性颗粒; 其中所述Ag和所述Au在含Co磁性晶粒中基本上不混溶。
-
公开(公告)号：US06998137B2
公开(公告)日：2006-02-14
申请号：US09827100
申请日：2001-04-05
申请人： Chung Shih , Gaylen Zentner , Ai-Zhi Piao
发明人： Chung Shih , Gaylen Zentner , Ai-Zhi Piao
摘要： The present invention relates to compositions and methods for the modulated release of one or more proteins or peptides. The composition is comprised of a biocompatible polymeric matrix, a protein and/or peptide, and a sparingly water-soluble or essentially insoluble particle. The protein is deposited by adsorption or some other mechanism onto the sparingly water-soluble biocompatible particle wherein the protein-particle combination is dispersed within the polymeric matrix. The deposition of the protein onto the particle acts to modulate the release of the protein or peptide from dosage forms including long-acting dosage systems.
-
5.发明授权Agent delivering system comprised of microparticle and biodegradable gel with an improved releasing profile and methods of use thereof 有权由微粒和可生物降解的凝胶组成的具有改进的释放特征的药剂递送系统及其使用方法公开(公告)号：US06287588B1
公开(公告)日：2001-09-11
申请号：US09559507
申请日：2000-04-27
申请人： Chung Shih , Gaylen M. Zentner
发明人： Chung Shih , Gaylen M. Zentner
IPC分类号： A61F200
摘要： A composition and method for releasing a bio-active agent or a drug within a biological environment in a controlled manner is disclosed. The composition is a dual phase polymeric agent-delivery composition comprising a continuous biocompatible gel phase, a discontinuous particulate phase comprising defined microparticles and an agent to be delivered. A microparticle containing a bio-active agent is releasably entrained within a biocompatible polymeric gel matrix. The bio-active agent release may be contained in the microparticle phase alone or in both the microparticles and the gel matrix. The release of the agent is prolonged over a period of time, and the delivery may be modulated and/or controlled. In addition, a second agent may be loaded in some of the microparticles and/or the gel matrix.
摘要翻译： 公开了以可控制的方式在生物环境中释放生物活性剂或药物的组合物和方法。 组合物是双相聚合物递送组合物，其包含连续的生物相容性凝胶相，包含限定的微粒的不连续颗粒相和待递送的试剂。 含有生物活性剂的微粒可释放地夹带在生物相容性聚合物凝胶基质内。 生物活性剂释放可以单独包含在微粒相中，也可以包含在微粒和凝胶基质中。 试剂的释放在一段时间内延长，并且递送可以被调节和/或控制。 另外，第二种试剂可以装载在一些微粒和/或凝胶基质中。
-
公开(公告)号：US5837228A
公开(公告)日：1998-11-17
申请号：US939539
申请日：1992-09-02
IPC分类号： A61K9/00 , A61K9/20 , A61K9/58 , A61K31/35 , A61K31/365 , A61K31/74 , A61K47/48 , A61P33/00 , A61P33/10 , A61K9/14 , A61F2/02
CPC分类号： A61K9/0024 , A61K47/48192 , A61K47/482 , A61K9/204 , Y10S514/953
摘要： A bioerodible controlled release dosage form is disclosed comprising a polymer formed by condensing beneficial agents having a hydroxyl functionality of two or more with diketene acetals or divinyl ethers which delivers beneficial agents to a biological environment of use. A statistically significant portion of the beneficial agent is covalently bonded within the polymer matrix.
摘要翻译： 公开了一种生物腐蚀性控制释放剂型，其包含通过将具有两个或更多个羟基官能团的有益剂与双烯酮缩醛或二乙烯基醚缩合形成的聚合物，其将有益剂递送到生物生物学环境。 有益试剂的统计学显着部分共价键合在聚合物基质内。
-
公开(公告)号：US07999005B2
公开(公告)日：2011-08-16
申请号：US12277974
申请日：2008-11-25
IPC分类号： A01N31/335
CPC分类号： A61K9/0024 , A61K31/365 , A61K31/568 , A61K45/06 , A61K2300/00
摘要： An improved weight and growth stimulant for domesticated animals such as cattle, pigs and sheep is comprised of an anabolic agent that is subcutaneously administered in the form of a dual release implant formulation. Increased gains are particularly improved when zeranol is administered in an immediate-release and controlled-release formulation which allows for a one-time dosage injection.
摘要翻译： 用于驯养动物如牛，猪和绵羊的改善的重量和生长兴奋剂由以双重释放植入物制剂的形式皮下施用的合成代谢剂组成。 当使用允许进行一次剂量注射的速释制剂和控制释放制剂中施用Zeranol时，增加的益处特别好。
-
公开(公告)号：US20090264537A1
公开(公告)日：2009-10-22
申请号：US12490968
申请日：2009-06-24
申请人： Chung Shih , Gaylen M. Zentner
发明人： Chung Shih , Gaylen M. Zentner
IPC分类号： A61K47/34
CPC分类号： A61K47/34 , A61K9/0024 , A61K31/765 , A61K31/77 , A61K47/10 , C08G2261/126 , C08L71/02 , C08L2666/18 , C08L2666/02
摘要： An improved drug delivery composition and method of use is disclosed. The composition comprises one or more biodegradable block copolymer drug carriers; and a reconstitution enhancing and enabling agent comprising polyethylene glycol (PEG), a PEG derivative or a mixture of PEG and a PEG derivative. The composition can be administered as is or after being be dissolved or rapidly reconstituted in an aqueous vehicle to afford a homogeneous solution or uniform colloidal systems.
摘要翻译： 公开了改进的药物递送组合物和使用方法。 组合物包含一种或多种可生物降解的嵌段共聚物药物载体; 和包含聚乙二醇（PEG），PEG衍生物或PEG和PEG衍生物的混合物的重构增强和使能剂。 组合物可以按照或在被溶解或快速重构在水性载体中以提供均匀的溶液或均匀的胶体体系来施用。
-
公开(公告)号：US20070259901A1
公开(公告)日：2007-11-08
申请号：US11733591
申请日：2007-04-10
申请人： Gaylen Zentner , Chung Shih , James McRea
发明人： Gaylen Zentner , Chung Shih , James McRea
IPC分类号： A61K31/517 , A61P35/00
CPC分类号： A61K31/517 , A61K9/0019 , A61K47/10 , A61K47/44
摘要： The present invention relates to pharmaceutical compositions and dosage compositions of compounds, including injectable formulations for the parenteral delivery of such compounds into patients in need of such treatment. Also featured are methods of making and using the compositions, including methods for the treatment of neoplastic diseases.
摘要翻译： 本发明涉及化合物的药物组合物和剂量组合物，包括用于将这些化合物胃肠外递送给需要这种治疗的患者的可注射制剂。 还特征在于制备和使用组合物的方法，包括治疗肿瘤疾病的方法。
-
公开(公告)号：US20070249632A1
公开(公告)日：2007-10-25
申请号：US11692655
申请日：2007-03-28
申请人： Gaylen Zentner , Chung Shih , James McRea
发明人： Gaylen Zentner , Chung Shih , James McRea
IPC分类号： A61K31/517 , C07D239/72
CPC分类号： A61K31/517 , A61K9/0019 , A61K47/02 , A61K47/10 , A61K47/14 , A61K47/26 , Y02A50/465
摘要： The present invention relates to pharmaceutical compositions and dosage compositions of compounds, including injectable formulations for the parenteral delivery of such compounds into patients in need of such treatment. Also featured are methods of making and using the compositions, including methods for the treatment of neoplastic diseases.
-
-
-
-
-
-
-
-
-
搜索结果
31 条记录 (耗时 0.038 秒)
