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公开(公告)号:US20100048610A1
公开(公告)日:2010-02-25
申请号:US12474799
申请日:2009-05-29
申请人: Yuki Yamaguchi , Minoru Koura , Sayaka Kurobuchi , Takayuki Matsuda , Ayumu Okuda , Hisashi Sumida , Yuuichirou Watanabe , Takashi Enomoto , Kimiyuki Shibuya
发明人: Yuki Yamaguchi , Minoru Koura , Sayaka Kurobuchi , Takayuki Matsuda , Ayumu Okuda , Hisashi Sumida , Yuuichirou Watanabe , Takashi Enomoto , Kimiyuki Shibuya
IPC分类号: A61K31/436 , C07D401/06 , A61K31/4439 , C07D491/056
CPC分类号: C07D233/72 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D405/04 , C07D405/14 , C07D491/048
摘要: [Object] To provide a novel LXRβ agonist that is useful as a preventative and/or therapeutic agent for atherosclerosis; arteriosclerosis such as those resulting from diabetes; dyslipidemia; hypercholesterolemia; lipid-related diseases; inflammatory diseases that are caused by inflammatory cytokines; skin diseases such as allergic skin diseases; diabetes; or Alzheimer's disease.[Solving Means] A carbinol compound represented by the following general formula (I) or salt thereof, or their solvate.
摘要翻译: [目的]提供一种新型的LXR&bgr; 可用作动脉粥样硬化的预防和/或治疗剂的激动剂; 动脉硬化,如糖尿病引起的; 血脂异常 高胆固醇血症 脂质相关疾病; 由炎性细胞因子引起的炎性疾病; 皮肤病如过敏性皮肤病; 糖尿病; 或阿尔茨海默病。 [解决方案]由以下通式(I)表示的甲醇化合物或其盐或其溶剂化物。
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公开(公告)号:US20100063119A1
公开(公告)日:2010-03-11
申请号:US12516944
申请日:2007-11-29
申请人: Takayuki Matsuda , Ayumu Okuda , Minoru Koura , Yuki Yamaguchi , Sayaka Kurobuchi , Yuuichirou Watanabe , Kimiyuki Shibuya
发明人: Takayuki Matsuda , Ayumu Okuda , Minoru Koura , Yuki Yamaguchi , Sayaka Kurobuchi , Yuuichirou Watanabe , Kimiyuki Shibuya
IPC分类号: A61K31/4164 , C07D233/72 , C07D405/10 , C07D409/04 , A61K31/4178
CPC分类号: C07D233/72 , C07D233/76 , C07D233/78 , C07D235/02 , C07D401/04 , C07D403/04 , C07D405/04 , C07D409/04
摘要: There is provided a novel LXRβ agonist useful as a preventative and/or therapeutic agent for arteriosclerosis; arteriosclerosis such as those resulting from diabetes; hyperlipidemia; hypercholesterolemia; lipid-related diseases; inflammatory diseases caused by inflammatory cytokines, skin diseases such as allergic skin diseases, diabetes or Alzheimer's disease. The agonist is a carbinol derivative represented by the following general formula (1) or salt thereof, or their solvate.
摘要翻译: 提供了一个新颖的LXR&bgr; 可用作动脉硬化的预防和/或治疗剂的激动剂; 动脉硬化,如糖尿病引起的; 高脂血症 高胆固醇血症 脂质相关疾病; 由炎性细胞因子引起的炎性疾病,皮肤疾病如过敏性皮肤疾病,糖尿病或阿尔茨海默病。 激动剂是由以下通式(1)表示的甲醇衍生物或其盐或其溶剂合物。
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公开(公告)号:US08168666B2
公开(公告)日:2012-05-01
申请号:US12516944
申请日:2007-11-29
申请人: Takayuki Matsuda , Ayumu Okuda , Minoru Koura , Yuki Yamaguchi , Sayaka Kurobuchi , Yuuichirou Watanabe , Kimiyuki Shibuya
发明人: Takayuki Matsuda , Ayumu Okuda , Minoru Koura , Yuki Yamaguchi , Sayaka Kurobuchi , Yuuichirou Watanabe , Kimiyuki Shibuya
IPC分类号: A61K31/4015 , C07D233/32
CPC分类号: C07D233/72 , C07D233/76 , C07D233/78 , C07D235/02 , C07D401/04 , C07D403/04 , C07D405/04 , C07D409/04
摘要: There is provided a novel LXRβ agonist useful as a preventative and/or therapeutic agent for arteriosclerosis; arteriosclerosis such as those resulting from diabetes; hyperlipidemia; hypercholesterolemia; lipid-related diseases; inflammatory diseases caused by inflammatory cytokines, skin diseases such as allergic skin diseases, diabetes or Alzheimer's disease. The agonist is a carbinol derivative represented by the following general formula (1) or salt thereof, or their solvate.
摘要翻译: 提供了一个新颖的LXR&bgr; 可用作动脉硬化的预防和/或治疗剂的激动剂; 动脉硬化,如糖尿病引起的; 高脂血症 高胆固醇血症 脂质相关疾病; 由炎性细胞因子引起的炎性疾病,皮肤疾病如过敏性皮肤疾病,糖尿病或阿尔茨海默病。 激动剂是由以下通式(1)表示的甲醇衍生物或其盐或其溶剂合物。
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公开(公告)号:US10253774B2
公开(公告)日:2019-04-09
申请号:US14346704
申请日:2012-08-29
IPC分类号: F04C23/00 , F04B39/02 , F04C29/00 , F04C18/356
摘要: A compressor includes a closed container housing a compression element driven by the shaft of a motor. The compression element includes a first and second bearings supporting first and second shaft portions, and at least one cylinder having at least one cylinder chamber disposed between the first and second bearings. At least one roller is fitted to the shaft in the at least one cylinder chamber. The first bearing is disposed closer to the motor than the second bearing. The first and second bearings have first and second annular grooves opened to the at least one cylinder chamber and first and second elastic portions provided in first and second opposing surfaces, respectively. A diameter of the second shaft portion is smaller than a diameter of the first shaft portion. A rigidity of the second elastic portion is smaller than a rigidity of the first elastic portion.
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公开(公告)号:US20140227116A1
公开(公告)日:2014-08-14
申请号:US14346701
申请日:2012-08-29
IPC分类号: F04C29/02 , F04C18/063
CPC分类号: F04C29/023 , F01C21/108 , F04C18/04 , F04C18/063 , F04C18/356 , F04C23/008 , F04C29/028 , F04C2240/56
摘要: A compressor includes a closed container, a compression element disposed in the closed container, and a motor disposed in the closed container to drive the compression element via a shaft. The compression element includes a first and second bearings supporting the shaft. At least one cylinder having at least one cylinder chamber is disposed between the first and second bearings, with at least one roller fitted to the shaft disposed in the at least one cylinder chamber. The first bearing is disposed closer to the motor than the second bearing. The first and second bearings have first and second annular grooves formed in first and second opposing surfaces opposed to end faces of the at least one roller. The first and second annular grooves are opened to the at least one cylinder chamber. A width of the second annular groove is larger than a width of the first annular groove.
摘要翻译: 压缩机包括密封容器,设置在密闭容器中的压缩元件和设置在密闭容器中的电动机,以经由轴驱动压缩元件。 压缩元件包括支撑轴的第一和第二轴承。 具有至少一个气缸室的至少一个气缸设置在第一和第二轴承之间,其中至少一个辊安装在设置在至少一个汽缸室中的轴上。 第一轴承比第二轴承更靠近马达设置。 第一和第二轴承具有形成在与至少一个辊的端面相对的第一和第二相对表面中的第一和第二环形槽。 第一和第二环形槽向至少一个气缸室敞开。 第二环形槽的宽度大于第一环形槽的宽度。
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公开(公告)号:US07823560B2
公开(公告)日:2010-11-02
申请号:US12418395
申请日:2009-04-03
IPC分类号: F02D9/00
CPC分类号: B62K11/04 , B60W2510/0638 , B60W2520/10 , B60W2540/10 , F02D11/105 , F02D31/002 , F02D2011/102 , F02D2200/602 , Y10T477/753
摘要: A straddle-type vehicle includes an engine, an air intake pipe, a throttle valve being controlled in accordance with an operation amount of an accelerator grip, an engine rotating speed detector or a vehicle speed detector, and an electronic control unit (ECU). The ECU increases the opening degree of the throttle valve or maintains the opening degree at a constant value until the engine rotating speed reaches a set rotating speed which is smaller than a prescribed rotating speed, but if the engine rotating speed exceeds the set rotating speed, the ECU reduces the opening degree of the throttle valve irrespective of operation of the accelerator grip.
摘要翻译: 一种跨乘式车辆包括发动机,进气管,根据加速踏板的操作量控制的节气门,发动机转速检测器或车速检测器以及电子控制单元(ECU)。 ECU增加节流阀的开度,或将开度维持在恒定值,直到发动机转速达到比规定转速小的设定转速,但如果发动机转速超过设定转速, 无论加速器夹持的操作如何,ECU都会减小节流阀的开度。
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公开(公告)号:US20090260908A1
公开(公告)日:2009-10-22
申请号:US12418395
申请日:2009-04-03
CPC分类号: B62K11/04 , B60W2510/0638 , B60W2520/10 , B60W2540/10 , F02D11/105 , F02D31/002 , F02D2011/102 , F02D2200/602 , Y10T477/753
摘要: A straddle-type vehicle includes an engine, an air intake pipe, a throttle valve being controlled in accordance with an operation amount of an accelerator grip, an engine rotating speed detector or a vehicle speed detector, and an electronic control unit (ECU). The ECU increases the opening degree of the throttle valve or maintains the opening degree at a constant value until the engine rotating speed reaches a set rotating speed which is smaller than a prescribed rotating speed, but if the engine rotating speed exceeds the set rotating speed, the ECU reduces the opening degree of the throttle valve irrespective of operation of the accelerator grip.
摘要翻译: 一种跨乘式车辆包括发动机,进气管,根据加速踏板的操作量控制的节气门,发动机转速检测器或车速检测器以及电子控制单元(ECU)。 ECU增加节流阀的开度,或将开度维持在恒定值,直到发动机转速达到比规定转速小的设定转速,但如果发动机转速超过设定转速, 无论加速器夹持的操作如何,ECU都会减小节流阀的开度。
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公开(公告)号:US09709058B2
公开(公告)日:2017-07-18
申请号:US14346701
申请日:2012-08-29
IPC分类号: F04C18/04 , F04C29/02 , F01C21/10 , F04C18/356 , F04C18/063 , F04C23/00
CPC分类号: F04C29/023 , F01C21/108 , F04C18/04 , F04C18/063 , F04C18/356 , F04C23/008 , F04C29/028 , F04C2240/56
摘要: A compressor includes a closed container, a compression element disposed in the closed container, and a motor disposed in the closed container to drive the compression element via a shaft. The compression element includes a first and second bearings supporting the shaft. At least one cylinder having at least one cylinder chamber is disposed between the first and second bearings, with at least one roller fitted to the shaft disposed in the at least one cylinder chamber. The first bearing is disposed closer to the motor than the second bearing. The first and second bearings have first and second annular grooves formed in first and second opposing surfaces opposed to end faces of the at least one roller. The first and second annular grooves are opened to the at least one cylinder chamber. A width of the second annular groove is larger than a width of the first annular groove.
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公开(公告)号:US20140219833A1
公开(公告)日:2014-08-07
申请号:US14346704
申请日:2012-08-29
IPC分类号: F04B35/00
CPC分类号: F04C23/008 , F04B39/0246 , F04B39/0253 , F04C18/356 , F04C29/0021 , F04C2240/601
摘要: A compressor includes a closed container housing a compression element driven by the shaft of a motor. The compression element includes a first and second bearings supporting first and second shaft portions, and at least one cylinder having at least one cylinder chamber disposed between the first and second bearings. At least one roller is fitted to the shaft in the at least one cylinder chamber. The first bearing is disposed closer to the motor than the second bearing. The first and second bearings have first and second annular grooves opened to the at least one cylinder chamber and first and second elastic portions provided in first and second opposing surfaces, respectively. A diameter of the second shaft portion is smaller than a diameter of the first shaft portion. A rigidity of the second elastic portion is smaller than a rigidity of the first elastic portion.
摘要翻译: 压缩机包括容纳由电动机的轴驱动的压缩元件的密闭容器。 压缩元件包括支撑第一和第二轴部分的第一和第二轴承,以及至少一个具有设置在第一和第二轴承之间的至少一个气缸室的气缸。 至少一个气缸室中的至少一个辊安装在轴上。 第一轴承比第二轴承更靠近马达设置。 第一和第二轴承具有向至少一个气缸室敞开的第一和第二环形槽,分别设置在第一和第二相对表面中的第一和第二弹性部分。 第二轴部的直径小于第一轴部的直径。 第二弹性部的刚性小于第一弹性部的刚性。
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