专利检索 ap:("ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.") AND inv:"Nayan Patel" 第 1 页

1.

发明授权
Cyanine dye compound and preparation method therefor, and dual-function agent for photodynamic therapy and preparation method therefor 有权

公开(公告)号：US09821062B2

公开(公告)日：2017-11-21

申请号：US14758427

申请日：2013-02-06

申请人： ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

发明人： Ravindra K. Pandey , Nayan Patel , Manivannan Ethirajan , Hua Bai , Zhenliang Chen

IPC分类号： C07B47/00 , C07D487/22 , A61K41/00 , C09B23/04 , C07D403/14 , C07D209/60

CPC分类号： A61K41/0057 , A61K41/0071 , C07D209/60 , C07D403/14 , C07D487/22 , C09B23/04

摘要： Disclosed are a cyanine dye compound and a preparation method therefor, and a dual-function agent for photodynamic therapy and a preparation method therefor. The provided cyanine dye compound is connected to multiple markers, which improves the accuracy of combination of dye and tumor cells, effectively reduces the background value, and avoids excessive residues in the liver. The provided cyanine dye compound is conjugated with the photosensitizer at 2′″ position, so that tumor highly absorbs the conjugates.