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1.发明授权5-heterocyclyl pyrazolo[4,3-d]pyrimidin-7-ones for the treatment of male erectile dysfunction 有权5-杂环基吡唑并[4,3-d]嘧啶-7-酮用于治疗男性勃起功能障碍
公开(公告)号：US6077841A
公开(公告)日：2000-06-20
申请号：US388851
申请日：1999-09-02
申请人： Zhihua Sui , Jihua Guan , Mark J. Macielag
发明人： Zhihua Sui , Jihua Guan , Mark J. Macielag
IPC分类号： A61K31/519 , A61P9/04 , A61P9/10 , A61P9/12 , A61P15/10 , C07D487/04
CPC分类号： C07D487/04
摘要： The invention is directed to novel substituted 5-heterocyclyl pyrazolopyrimidinones and derivatives thereof, their synthesis and their use in treating sexual dysfunction in mammals, especially male erectile dysfunction. Pharmaceutical compositions containing the compounds and methods of using them to treat sexual dysfunction are also described.
摘要翻译： 本发明涉及新型取代的5-杂环基吡唑并嘧啶酮及其衍生物，其合成及其在治疗哺乳动物性功能障碍，特别是雄性勃起功能障碍中的用途。 还描述了含有化合物的药物组合物和使用它们治疗性功能障碍的方法。
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2.发明授权Substituted pyrrolopyridinone derivatives useful as phosphodiesterase inhibitors 有权用作磷酸二酯酶抑制剂的取代的吡咯并吡喃酮衍生物公开(公告)号：US06818646B2
公开(公告)日：2004-11-16
申请号：US10638901
申请日：2003-08-11
申请人： Zhihua Sui , Mark J. Macielag , Jihua Guan , Weigin Jiang , James C. Lanter
发明人： Zhihua Sui , Mark J. Macielag , Jihua Guan , Weigin Jiang , James C. Lanter
IPC分类号： A61K314965
CPC分类号： C07D471/04
摘要： The invention relates to novel pyrrolopyridinone derivatives of the formula (I) or (II): pharmaceutical compositions containing the compounds and their use for the treatment of sexual dysfunction.
摘要翻译： 本发明涉及式（I）或（II）的新型吡咯并吡喃酮衍生物：含有化合物的药物组合物及其用于治疗性功能障碍的用途。
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3.发明授权Substituted pyrrolopyridinone derivatives useful as phosphodiesterase inhibitors 有权用作磷酸二酯酶抑制剂的取代的吡咯并吡喃酮衍生物公开(公告)号：US06635638B2
公开(公告)日：2003-10-21
申请号：US09847749
申请日：2001-05-02
申请人： Zhihua Sui , Mark J. Macielag , Jihua Guan , Weiqin Jiang , James C. Lanter
发明人： Zhihua Sui , Mark J. Macielag , Jihua Guan , Weiqin Jiang , James C. Lanter
IPC分类号： C07D47104
CPC分类号： C07D471/04
摘要： The invention relates to novel pyrrolopyridinone derivatives of the formula (I) or (II): pharmaceutical compositions containing the compounds and their use for the treatment of sexual dysfunction.
摘要翻译： 本发明涉及式（I）或（II）的新型吡咯并吡喃酮衍生物：含有化合物的药物组合物及其用于治疗性功能障碍的用途。
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4.发明申请NOVEL BENZIMIDAZOLE DERIVATIVES USEFUL AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) 有权新型苯并咪唑衍生物作为选择性受体调节剂（SARMS）有用公开(公告)号：US20110086883A1
公开(公告)日：2011-04-14
申请号：US12970554
申请日：2010-12-16
申请人： Raymond Ng , Zhihua Sui , Jihua Guan , James C. Lanter , Vernon C. Alford, JR.
发明人： Raymond Ng , Zhihua Sui , Jihua Guan , James C. Lanter , Vernon C. Alford, JR.
IPC分类号： A61K31/4439 , A61K31/4184 , A61K31/422 , A61K31/433 , A61P35/00 , A61P25/00 , A61P17/10 , A61P31/18 , A61P15/10
CPC分类号： C07D403/06 , C07D235/10 , C07D235/12 , C07D235/16 , C07D401/06 , C07D403/10 , C07D405/06 , C07D409/06 , C07D409/14 , C07D413/06 , C07D417/10
摘要： The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
摘要翻译： 本发明涉及新的苯并咪唑衍生物，含有它们的药物组合物及其在治疗由雄激素受体调节的病症和状况中的用途。
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5.发明申请NOVEL BENZIMIDAZOLE DERIVATIVES USEFUL AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) 审中-公开新型苯并咪唑衍生物作为选择性受体调节剂（SARMS）有用公开(公告)号：US20100298383A1
公开(公告)日：2010-11-25
申请号：US12849378
申请日：2010-08-03
申请人： Raymond Ng , Zhihua Sui , Jihua Guan , James C. Lanter , Vernon C. Alford, JR.
发明人： Raymond Ng , Zhihua Sui , Jihua Guan , James C. Lanter , Vernon C. Alford, JR.
IPC分类号： A61K31/4439 , A61K31/4184 , A61K31/422 , A61K31/433 , A61P43/00 , A61P35/00 , A61P3/04 , A61P17/14 , A61P31/18 , A61P15/16 , A61P15/00 , A61P17/10
CPC分类号： C07D405/06 , C07D235/10 , C07D235/12 , C07D235/14 , C07D235/16 , C07D401/06 , C07D403/10 , C07D409/06 , C07D409/14 , C07D413/06 , C07D417/10
摘要： The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
摘要翻译： 本发明涉及新的苯并咪唑衍生物，含有它们的药物组合物及其在治疗由雄激素受体调节的病症和状况中的用途。
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6.发明申请Novel benzimidazole derivatives useful as selective androgen receptor modulators (SARMS) 有权用作选择性雄激素受体调节剂（SARMS）的新型苯并咪唑衍生物公开(公告)号：US20060111402A1
公开(公告)日：2006-05-25
申请号：US11235581
申请日：2005-09-26
申请人： Raymond Ng , Zhihua Sui , Jihua Guan , James Lanter , Vernon Alford
发明人： Raymond Ng , Zhihua Sui , Jihua Guan , James Lanter , Vernon Alford
IPC分类号： A61K31/4439 , A61K31/4184 , C07D403/02
CPC分类号： C07D405/06 , C07D235/10 , C07D235/12 , C07D235/14 , C07D235/16 , C07D401/06 , C07D403/10 , C07D409/06 , C07D409/14 , C07D413/06 , C07D417/10
摘要： The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
摘要翻译： 本发明涉及新的苯并咪唑衍生物，含有它们的药物组合物及其在治疗由雄激素受体调节的病症和状况中的用途。
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7.发明申请Substituted pyrrolopyridinone derivatives useful as phosphodiesterase inhibitors 审中-公开用作磷酸二酯酶抑制剂的取代的吡咯并吡喃酮衍生物公开(公告)号：US20050113402A1
公开(公告)日：2005-05-26
申请号：US10971476
申请日：2004-10-22
申请人： Zhihua Sui , Mark Macielag , Jihua Guan , Weigin Jiang , James Lanter
发明人： Zhihua Sui , Mark Macielag , Jihua Guan , Weigin Jiang , James Lanter
IPC分类号： A61K31/437 , A61K31/4709 , A61K31/496 , A61K31/506 , A61K31/5377 , A61P3/10 , A61P7/02 , A61P9/00 , A61P9/04 , A61P9/10 , A61P9/12 , A61P11/06 , A61P15/00 , A61P15/02 , A61P15/06 , A61P15/08 , A61P15/10 , A61P43/00 , C07D471/04 , A61K31/4745 , C07D471/02
CPC分类号： C07D471/04
摘要： The invention relates to novel pyrrolopyridinone derivatives of the formula (I) or (II): pharmaceutical compositions containing the compounds and their use for the treatment of sexual dysfunction.
摘要翻译： 本发明涉及式（I）或（II）的新型吡咯并吡喃酮衍生物：含有化合物的药物组合物及其用于治疗性功能障碍的用途。
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8.发明授权Benzimidazole derivatives useful as selective androgen receptor modulators (SARMS) 有权可用作选择性雄激素受体调节剂（SARMS）的苯并咪唑衍生物公开(公告)号：US07879895B2
公开(公告)日：2011-02-01
申请号：US12488752
申请日：2009-06-22
申请人： Raymond Ng , Zhihua Sui , Jihua Guan , James C. Lanter , Vernon C. Alford, Jr.
发明人： Raymond Ng , Zhihua Sui , Jihua Guan , James C. Lanter , Vernon C. Alford, Jr.
IPC分类号： A61K31/4184 , C07D235/12
CPC分类号： C07D403/06 , C07D235/10 , C07D235/12 , C07D235/16 , C07D401/06 , C07D403/10 , C07D405/06 , C07D409/06 , C07D409/14 , C07D413/06 , C07D417/10
摘要： The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
摘要翻译： 本发明涉及新的苯并咪唑衍生物，含有它们的药物组合物及其在治疗由雄激素受体调节的病症和状况中的用途。
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9.发明授权Benzimidazole derivatives useful as selective androgen receptor modulators (SARMS) 有权可用作选择性雄激素受体调节剂（SARMS）的苯并咪唑衍生物公开(公告)号：US07795446B2
公开(公告)日：2010-09-14
申请号：US12019764
申请日：2008-01-25
申请人： Raymond Ng , Zhihua Sui , Jihua Guan , James C. Lanter , Vernon C. Alford, Jr.
发明人： Raymond Ng , Zhihua Sui , Jihua Guan , James C. Lanter , Vernon C. Alford, Jr.
IPC分类号： A61K31/4184 , C07D235/10
CPC分类号： C07D405/06 , C07D235/10 , C07D235/12 , C07D235/14 , C07D235/16 , C07D401/06 , C07D403/10 , C07D409/06 , C07D409/14 , C07D413/06 , C07D417/10
摘要： The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
摘要翻译： 本发明涉及新的苯并咪唑衍生物，含有它们的药物组合物及其在治疗由雄激素受体调节的病症和状况中的用途。
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10.发明申请Novel Benzimidazole Derivatives Useful as Selective Androgen Receptor Modulators (SARMS) 有权用作选择性雄激素受体调节剂的新型苯并咪唑衍生物（SARMS）公开(公告)号：US20090258909A1
公开(公告)日：2009-10-15
申请号：US12488752
申请日：2009-06-22
申请人： Raymond Ng , Zhihua Sui , Jihua Guan , James C. Lanter , Vernon C. Alford, JR.
发明人： Raymond Ng , Zhihua Sui , Jihua Guan , James C. Lanter , Vernon C. Alford, JR.
IPC分类号： A61K31/4439 , C07D235/16 , A61K31/4184 , C07D409/14 , A61P35/00
CPC分类号： C07D403/06 , C07D235/10 , C07D235/12 , C07D235/16 , C07D401/06 , C07D403/10 , C07D405/06 , C07D409/06 , C07D409/14 , C07D413/06 , C07D417/10
摘要： The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
摘要翻译： 本发明涉及新的苯并咪唑衍生物，含有它们的药物组合物及其在治疗由雄激素受体调节的病症和状况中的用途。
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