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    Pteridines and their use as agrochemicals
    5.
    发明授权
    Pteridines and their use as agrochemicals 有权
    蝶啶及其作为农用化学品的用途

    公开(公告)号：US08461164B2

    公开(公告)日：2013-06-11

    申请号：US12551008

    申请日：2009-08-31

    申请人： William K. Brewster ,  David A. Demeter ,  W. Randal Erickson ,  Christian T. Lowe ,  Carla J. R. Klittich ,  Jaime S. Nugent ,  Brent J. Rieder ,  Thomas L. Siddall ,  Chenglin Yao ,  Carla N. Yerkes ,  Yuanming Zhu

    发明人： William K. Brewster ,  David A. Demeter ,  W. Randal Erickson ,  Christian T. Lowe ,  Carla J. R. Klittich ,  Jaime S. Nugent ,  Brent J. Rieder ,  Thomas L. Siddall ,  Chenglin Yao ,  Carla N. Yerkes ,  Yuanming Zhu

    IPC分类号： A61K31/519

    CPC分类号： A01N43/90 ,  C07D475/06

    摘要： The present disclosure relates to 1- or 2-(4-(aryloxy)-phenyl)ethylamino-, oxy- or sulfanyl)pteridines and 1- or 2-(4-(heteroaryloxy)-phenyl)ethylamino-, oxy- or sulfanyl)pteridines and their use as agrochemicals and animal health products. More specifically, the invention provides new compounds of the formula (I-A): wherein: R is H, CH3, phenyl, or a heterocycle comprising a 5 or 6 membered single ring or a fused ring system comprising at least one 5 or 6 membered heterocycle optionally substituted with H, halo, lower alkyl, lower alkoxy, benzyloxy, lower alkenyl, lower alkynyl, haloalkyl, haloalkoxy, NO2, CN, lower alkoxycarbonyl, lower alkylcarbonyl, lower alkyl-SOq, and aldoximes and lower alkyloximes, optionally substituted on oxygen by lower alkyl. Z is H, a C—C single bond, CH2, NH, O, S, CN, CH2O, OCH2, CH2CH2O, or OCH2CH2: m is 4; p is 0 or 1; q is an integer from 0 to 2; R1 is independently H, halo, lower alkyl, lower alkenyl, lower alkynyl, hydroxy, lower alkoxy, haloalkyl, haloalkoxy, NO2, CN, lower alkylcarbonyl, lower alkoxycarbonyl, mercapto, lower alkylthio, aldoximes and lower alkyloximes, optionally substituted on oxygen by lower alkyl; Y is a C—C single bond, C(R5n)O or C(R5n); n is 2.

    摘要翻译： 本公开涉及1-或2-（4-（芳氧基） - 苯基）乙基氨基 - ，氧基或硫烷基）蝶啶和1-或2-（4-（杂芳氧基） - 苯基）乙基氨基 - ，氧基或硫烷基 ）蝶啶及其作为农药和动物保健品的用途。 更具体地，本发明提供新的式（IA）化合物：其中：R是H，CH 3，苯基或包含5或6元单环或稠环体系的杂环，其包含至少一个5或6元杂环 任选被H，卤素，低级烷基，低级烷氧基，苄氧基，低级烯基，低级炔基，卤代烷基，卤代烷氧基，NO2，CN，低级烷氧基羰基，低级烷基羰基，低级烷基-SO 2，和低级烷基肟取代， 通过低级烷基。 Z为H，C-C单键，CH2，NH，O，S，CN，CH2O，OCH2，CH2CH2O或OCH2CH2：m为4; p为0或1; q是0至2的整数; R1独立地是H，卤素，低级烷基，低级烯基，低级炔基，羟基，低级烷氧基，卤代烷基，卤代烷氧基，NO2，CN，低级烷基羰基，低级烷氧基羰基，巯基，低级烷硫基，醛基和低级烷基肟基， 低级烷基 Y是C-C单键，C（R5n）O或C（R5n）; n是2。