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公开(公告)号:US09006468B2
公开(公告)日:2015-04-14
申请号:US13358090
申请日:2012-01-25
Applicant: Gary D. Crouse , Thomas C. Sparks , CaSandra L. McLeod , David A. Demeter , Kristy Bryan , Annette V. Brown , William H. Dent, III , Denise P. Cudworth , Jaime S. Nugent , Ricky Hunter , Jack G. Samaritoni
Inventor: Gary D. Crouse , Thomas C. Sparks , CaSandra L. McLeod , David A. Demeter , Kristy Bryan , Annette V. Brown , William H. Dent, III , Denise P. Cudworth , Jaime S. Nugent , Ricky Hunter , Jack G. Samaritoni
IPC: C07D309/10 , C07D309/12 , C07H15/18 , C07H15/26 , C07H13/12 , A01N51/00 , A01N47/06 , A01N47/02 , A01N47/18 , A01N47/20 , A61K31/7064 , A61K31/7048 , A61K31/7034 , A01N43/00 , A01N43/16 , A01N43/40 , A01N43/50 , A01N43/653 , G06Q99/00
CPC classification number: C07H13/12 , A01N43/00 , A01N43/16 , A01N43/36 , A01N43/40 , A01N43/50 , A01N43/56 , A01N43/653 , A01N43/72 , A01N43/76 , A01N43/78 , A01N43/80 , A01N43/82 , A01N47/02 , A01N47/06 , A01N47/18 , A01N51/00 , C07D309/10 , C07D309/12 , C07D405/14 , C07D407/14 , C07H15/18 , C07H15/26 , G06Q99/00
Abstract: The invention disclosed in this document is related to the field of pesticides and their use in controlling pests. A compound having the following structure is disclosed.
Abstract translation: 本文件披露的发明涉及农药领域及其在防治害虫方面的应用。 公开了具有以下结构的化合物。
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公开(公告)号:US20120122805A1
公开(公告)日:2012-05-17
申请号:US13358090
申请日:2012-01-25
Applicant: Gary D. Crouse , Thomas C. Sparks , CaSandra Lee McLeod , David A. Demeter , Kristy Bryan , Annette V. Brown , William H. Dent, III , Denise P. Cudworth , Jaime S. Nugent , Ricky Hunter , Jack G. Samaritoni
Inventor: Gary D. Crouse , Thomas C. Sparks , CaSandra Lee McLeod , David A. Demeter , Kristy Bryan , Annette V. Brown , William H. Dent, III , Denise P. Cudworth , Jaime S. Nugent , Ricky Hunter , Jack G. Samaritoni
IPC: A01N43/50 , A01N43/653 , A01N43/40 , A01N43/54 , A01N43/56 , G06Q90/00 , A61K31/7056 , A61K31/706 , A61K31/7064 , A61P33/00 , A01P5/00 , C07H15/26 , A01P7/04
CPC classification number: C07H13/12 , A01N43/00 , A01N43/16 , A01N43/36 , A01N43/40 , A01N43/50 , A01N43/56 , A01N43/653 , A01N43/72 , A01N43/76 , A01N43/78 , A01N43/80 , A01N43/82 , A01N47/02 , A01N47/06 , A01N47/18 , A01N51/00 , C07D309/10 , C07D309/12 , C07D405/14 , C07D407/14 , C07H15/18 , C07H15/26 , G06Q99/00
Abstract: The invention disclosed in this document is related to the field of pesticides and their use in controlling pests. A compound having the following structure is disclosed.
Abstract translation: 本文件披露的发明涉及农药领域及其在防治害虫方面的应用。 公开了具有以下结构的化合物。
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公开(公告)号:US07902233B2
公开(公告)日:2011-03-08
申请号:US12474928
申请日:2009-05-29
Applicant: Zoltan L. Benko , David A. Demeter , Carl Deamicis , Lowell Markley , Jack Geno Samaritoni , Carrie Schmidt , Yuanming Zhu , W. Randal Erickson , Peter B. Anzeveno , James Todd Pechacek , Gerald B. Watson , Gerrit Deboer , Joel J. Sheets , Susan Zabik , Carla N. Yerkes , Christian Schobert , James E. Dripps , Leonard Dintenfass , Laura L. Karr , Paul A. Neese , Jim X. Huang , James M. Gifford
Inventor: Zoltan L. Benko , David A. Demeter , Carl Deamicis , Lowell Markley , Jack Geno Samaritoni , Carrie Schmidt , Yuanming Zhu , W. Randal Erickson , Peter B. Anzeveno , James Todd Pechacek , Gerald B. Watson , Gerrit Deboer , Joel J. Sheets , Susan Zabik , Carla N. Yerkes , Christian Schobert , James E. Dripps , Leonard Dintenfass , Laura L. Karr , Paul A. Neese , Jim X. Huang , James M. Gifford
IPC: A61K31/44 , C07D211/82
CPC classification number: C07D401/04 , A01N43/40 , A01N43/60 , A01N47/40 , C07D213/61 , C07D213/64
Abstract: Compounds useful to control pests are provided.
Abstract translation: 提供了可用于防治害虫的化合物。
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公开(公告)号:US07018797B2
公开(公告)日:2006-03-28
申请号:US10162821
申请日:2002-06-05
Applicant: Allen B. Reitz , David A. Demeter , Daniel H. S. Lee , Hoau-Yan Wang , Robert H. Chen , Tina Morgan Ross , Malcolm K. Scott , Carlos R. Plata-Salaman
Inventor: Allen B. Reitz , David A. Demeter , Daniel H. S. Lee , Hoau-Yan Wang , Robert H. Chen , Tina Morgan Ross , Malcolm K. Scott , Carlos R. Plata-Salaman
CPC classification number: C07D295/096 , A61K31/00 , A61K31/135 , A61K31/5375 , C07C215/64 , C07C217/74 , C07C229/14 , C07C323/25 , C07C2602/10 , C07D295/088 , C07D333/20 , C07F9/3282
Abstract: The invention is directed to a method of treating a neurodegenerative disorder in a subject in need thereof which comprises administering to the subject an amount of a compound effective to inhibit the interaction of amyloid-beta with alpha-7 nicotinic acetylcholine receptors.
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公开(公告)号:US08178658B2
公开(公告)日:2012-05-15
申请号:US12369056
申请日:2009-02-11
Applicant: Gary D. Crouse , Thomas C. Sparks , CaSandra L. McLeod , David A. Demeter , Kristy Bryan , Annette V. Brown , William H. Dent, III , Denise P. Cudworth , Jaime S. Nugent , Ricky Hunter , Jack G. Samaritoni
Inventor: Gary D. Crouse , Thomas C. Sparks , CaSandra L. McLeod , David A. Demeter , Kristy Bryan , Annette V. Brown , William H. Dent, III , Denise P. Cudworth , Jaime S. Nugent , Ricky Hunter , Jack G. Samaritoni
IPC: A61K31/7034 , A61K31/7048 , A61K31/706 , A61K31/7056 , A61K31/35 , C07H17/04 , C07D309/10 , C07D309/12
CPC classification number: C07H13/12 , A01N43/00 , A01N43/16 , A01N43/36 , A01N43/40 , A01N43/50 , A01N43/56 , A01N43/653 , A01N43/72 , A01N43/76 , A01N43/78 , A01N43/80 , A01N43/82 , A01N47/02 , A01N47/06 , A01N47/18 , A01N51/00 , C07D309/10 , C07D309/12 , C07D405/14 , C07D407/14 , C07H15/18 , C07H15/26 , G06Q99/00
Abstract: The invention disclosed in this document is related to the field of pesticides and their use in controlling pests. A compound having the following structure is disclosed.
Abstract translation: 本文件披露的发明涉及农药领域及其在防治害虫方面的应用。 公开了具有以下结构的化合物。
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6.Method of treating neurodegenerative disorders via inhibition of amyloid beta peptide binding 有权
Title translation: 通过抑制淀粉样蛋白β肽结合治疗神经变性疾病的方法公开(公告)号:US06441049B2
公开(公告)日:2002-08-27
申请号:US09320885
申请日:1999-05-27
Applicant: Allen B. Reitz , David A. Demeter , Daniel H. S. Lee , Hoau-Yan Wang , Robert H. Chen , Tina Morgan Ross , Malcolm K. Scott , Carlos R. Plata-Salaman
Inventor: Allen B. Reitz , David A. Demeter , Daniel H. S. Lee , Hoau-Yan Wang , Robert H. Chen , Tina Morgan Ross , Malcolm K. Scott , Carlos R. Plata-Salaman
IPC: A61K31135
CPC classification number: C07D295/096 , A61K31/00 , A61K31/135 , A61K31/5375 , C07C215/64 , C07C217/74 , C07C229/14 , C07C323/25 , C07C2602/10 , C07D295/088 , C07D333/20 , C07F9/3282
Abstract: The invention is directed to a method of treating a neurodegenerative disorder in a subject in need thereof which comprises administering to the subject an amount of a compound effective to inhibit the interaction of amyloid-beta with alpha-7 nicotinic acetylcholine receptors.
Abstract translation: 本发明涉及一种在有需要的受试者中治疗神经变性疾病的方法,该方法包括向受试者施用一定量的有效抑制淀粉样蛋白-β与α-7烟碱乙酰胆碱受体相互作用的化合物。
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公开(公告)号:US09018363B2
公开(公告)日:2015-04-28
申请号:US13420729
申请日:2012-03-15
Applicant: Gary D. Crouse , Thomas C. Sparks , CaSandra L. McLeod , David A. Demeter , Kristy Bryan , Annette V. Brown , William H. Dent, III , Denise P. Cudworth , Jaime S. Nugent , Ricky Hunter , Jack G. Samaritoni
Inventor: Gary D. Crouse , Thomas C. Sparks , CaSandra L. McLeod , David A. Demeter , Kristy Bryan , Annette V. Brown , William H. Dent, III , Denise P. Cudworth , Jaime S. Nugent , Ricky Hunter , Jack G. Samaritoni
IPC: C07H13/12 , C07H15/26 , C07H15/18 , C07D309/12 , A01N51/00 , A01N47/06 , C07D309/10 , A01N43/00 , A01N43/16 , A01N43/40 , A01N43/50 , A01N43/653 , A01N47/02 , A01N47/18 , G06Q99/00
CPC classification number: C07H13/12 , A01N43/00 , A01N43/16 , A01N43/36 , A01N43/40 , A01N43/50 , A01N43/56 , A01N43/653 , A01N43/72 , A01N43/76 , A01N43/78 , A01N43/80 , A01N43/82 , A01N47/02 , A01N47/06 , A01N47/18 , A01N51/00 , C07D309/10 , C07D309/12 , C07D405/14 , C07D407/14 , C07H15/18 , C07H15/26 , G06Q99/00
Abstract: The invention disclosed in this document is related to the field of pesticides and their use in controlling pests. A compound having the following structure is disclosed.
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公开(公告)号:US20120202687A1
公开(公告)日:2012-08-09
申请号:US13366602
申请日:2012-02-06
Applicant: Gary D. Crouse , Thomas C. Sparks , William H. Dent, III , CaSandra L. McLeod , Lawrence C. Creemer , David A. Demeter , Amanda E. Fritz , Lindsey G. Fischer , Erich W. Baum
Inventor: Gary D. Crouse , Thomas C. Sparks , William H. Dent, III , CaSandra L. McLeod , Lawrence C. Creemer , David A. Demeter , Amanda E. Fritz , Lindsey G. Fischer , Erich W. Baum
IPC: A01C1/06 , C07F7/10 , C07D413/12 , C07D405/12 , C07D495/04 , C07D401/12 , C07D403/12 , C07D417/12 , C07D417/14 , A01N43/653 , A01N55/10 , A01N43/76 , A01N43/80 , A61K31/454 , A61K31/496 , A01N43/78 , A61K31/427 , A01N43/86 , A01N43/72 , A01P7/04 , A01P5/00 , A01P3/00 , A01P13/00 , A01P7/02 , A01N43/90 , A61K31/4196 , A61K31/695 , A61K31/422 , A61K31/541 , A61K31/554 , A61P33/00 , A61P33/14 , A61K31/4439 , C07D249/08
CPC classification number: A01N43/60 , A01N43/653 , A01N43/72 , A01N43/76 , A01N43/78 , A01N43/80 , A01N43/86 , A01N43/90 , A01N47/34 , A01N47/42 , A61K45/06 , C07D249/08 , C07D401/12 , C07D403/12 , C07D405/12 , C07D413/12 , C07D417/12 , C07D417/14 , C07D495/04 , C07F7/0812
Abstract: This document discloses molecules having the following formulas (“Formula One” & “Formula Two” and “Formula Three”) The Ar1, Het, Ar2, R1, R2, R3, R4, and R5 are further described herein.
Abstract translation: 该文献公开了具有下式(“一级”,“二式”和“式三”)的分子。本文进一步描述了Ar1,Het,Ar2,R1,R2,R3,R4和R5。
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公开(公告)号:US20090209476A1
公开(公告)日:2009-08-20
申请号:US12369056
申请日:2009-02-11
Applicant: Gary D. Crouse , Thomas C. Sparks , CaSandra L. McLead , David A. Demeter , Kristy Bryan , Annette V. Brown , William H. Dent, III , Denise P. Cudworth , Jaime S. Nugent , Ricky Hunter , Jack G. Samaritoni
Inventor: Gary D. Crouse , Thomas C. Sparks , CaSandra L. McLead , David A. Demeter , Kristy Bryan , Annette V. Brown , William H. Dent, III , Denise P. Cudworth , Jaime S. Nugent , Ricky Hunter , Jack G. Samaritoni
CPC classification number: C07H13/12 , A01N43/00 , A01N43/16 , A01N43/36 , A01N43/40 , A01N43/50 , A01N43/56 , A01N43/653 , A01N43/72 , A01N43/76 , A01N43/78 , A01N43/80 , A01N43/82 , A01N47/02 , A01N47/06 , A01N47/18 , A01N51/00 , C07D309/10 , C07D309/12 , C07D405/14 , C07D407/14 , C07H15/18 , C07H15/26 , G06Q99/00
Abstract: The invention disclosed in this document is related to the field of pesticides and their use in controlling pests. A compound having the following structure is disclosed.
Abstract translation: 本文件披露的发明涉及农药领域及其在防治害虫方面的应用。 公开了具有以下结构的化合物。
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公开(公告)号:US08815922B2
公开(公告)日:2014-08-26
申请号:US13366602
申请日:2012-02-06
Applicant: Gary D. Crouse , Thomas C. Sparks , William H. Dent, III , CaSandra L. McLeod , Lawrence C. Creemer , David A. Demeter , Amanda E. Fritz , Lindsey G. Fischer , Erich W. Baum
Inventor: Gary D. Crouse , Thomas C. Sparks , William H. Dent, III , CaSandra L. McLeod , Lawrence C. Creemer , David A. Demeter , Amanda E. Fritz , Lindsey G. Fischer , Erich W. Baum
IPC: A61K31/427 , A61K31/422 , C07D263/30 , C07D277/04
CPC classification number: A01N43/60 , A01N43/653 , A01N43/72 , A01N43/76 , A01N43/78 , A01N43/80 , A01N43/86 , A01N43/90 , A01N47/34 , A01N47/42 , A61K45/06 , C07D249/08 , C07D401/12 , C07D403/12 , C07D405/12 , C07D413/12 , C07D417/12 , C07D417/14 , C07D495/04 , C07F7/0812
Abstract: This document discloses molecules having the following formulas (“Formula One” & “Formula Two” and “Formula Three”) The Ar1, Het, Ar2, R1, R2, R3, R4, and R5 are further described herein.
Abstract translation: 该文献公开了具有下式(“一级”,“二式”和“式三”)的分子。本文进一步描述了Ar1,Het,Ar2,R1,R2,R3,R4和R5。
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