公开(公告)号：US20170038368A1

公开(公告)日：2017-02-09

申请号：US15228890

申请日：2016-08-04

Applicant: uBiome, Inc.

Inventor： Zachary Apte ,  Nathan Saichek ,  Jessica Richman

IPC: G01N33/543 ,  G01N27/447 ,  C12Q1/68 ,  B01L3/00 ,  C12N15/10

CPC classification number: G01N33/5438 ,  B01L3/502707 ,  B01L3/502792 ,  B01L2200/0668 ,  B01L2200/0673 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/1827 ,  B01L2400/0427 ,  B01L2400/043 ,  G01N27/745 ,  G01N33/54326

Abstract: A system and method for sample droplet processing, the system including a substrate, an electrode array network coupled to the substrate and configured to provide a pattern of controlled electric fields for manipulation of the set of sample droplets; a first layer in communication with the electrode array network, the first layer separating the electrode array network from fluid of the set of sample droplets; and a second layer opposing the first layer and displaced from the first layer to define a region wherein droplets of the set of sample droplets can reside. In some variations, the system can additionally include an electronics subsystem coupled to at least one of the substrate and the electrode array network, and a control module in communication with the electronics subsystem, wherein the control module generates and manipulates the pattern of controlled electric fields.

Abstract translation: 一种用于样本液滴处理的系统和方法，所述系统包括基板，耦合到所述基板的电极阵列网络，并且被配置为提供用于操纵所述一组样品液滴的受控电场的图案; 与所述电极阵列网络连通的第一层，所述第一层将所述电极阵列网与所述一组样品液滴的流体分离; 以及与所述第一层相对并且从所述第一层移位的第二层，以限定所述一组样品液滴的液滴可以驻留的区域。 在一些变型中，该系统还可以包括耦合到衬底和电极阵列网络中的至少一个的电子子系统以及与电子子系统通信的控制模块，其中控制模块产生并操纵受控电场的模式 。