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20 条记录 (耗时 0.032 秒)

    Hydrogel composition for measuring glucose flux
    1.
    发明授权
    Hydrogel composition for measuring glucose flux 有权
    用于测量葡萄糖通量的水凝胶组合物

    公开(公告)号：US07150975B2

    公开(公告)日：2006-12-19

    申请号：US10643631

    申请日：2003-08-18

    申请人： Janet A. Tamada ,  Michael J. Tierney ,  Stephen C. Williams

    发明人： Janet A. Tamada ,  Michael J. Tierney ,  Stephen C. Williams

    IPC分类号： C12Q1/54

    CPC分类号： A61B5/1486 ,  A61N1/0436 ,  A61N1/044 ,  A61N1/325 ,  C08J3/075

    摘要： The present invention relates to compositions for use in analyte monitoring devices. These compositions are useful to increase the flux of analyte across skin, tissue or mucosal surfaces. The compositions include hydrogels and collection reservoir systems comprising ionically conductive materials. The present invention also includes methods of making/manufacturing hydrogels or collection reservoir systems, collection assemblies comprising the hydrogels, electrode assemblies in combination with the hydrogels or collection reservoir systems, and methods of using the same.

    摘要翻译： 本发明涉及用于分析物监测装置的组合物。 这些组合物可用于增加分析物通过皮肤，组织或粘膜表面的通量。 组合物包括包含离子导电材料的水凝胶和收集储存器系统。 本发明还包括制造/制造水凝胶或收集储存器系统的方法，包括水凝胶的收集组件，与水凝胶或收集储存器系统组合的电极组件及其使用方法。

    Electrochemical sensor ink compositions, electrodes, and uses thereof
    3.
    发明授权
    Electrochemical sensor ink compositions, electrodes, and uses thereof 有权

    公开(公告)号：US07189341B2

    公开(公告)日：2007-03-13

    申请号：US10692761

    申请日：2003-10-24

    申请人： Huawen Li ,  Michael J. Tierney

    发明人： Huawen Li ,  Michael J. Tierney

    IPC分类号： H01B1/22 ,  C25B11/04 ,  G01N27/327

    CPC分类号： C09D11/52 ,  C09D11/101 ,  C09D11/30 ,  G01N27/3271

    摘要： The invention is directed to conductive polymer compositions, catalytic ink compositions (e.g., for use in screen-printing), electrodes produced by deposition of an ink composition, as well as methods of making, and methods of using such compositions and electrodes. An exemplary ink material comprises a metal catalyst (e.g., platinum black and/or platinum-on-carbon), graphite as a conducting material, a polymer binding material, and an organic solvent. In one aspect, the polymer binding material comprises a polymer binder blend comprising first and second polymers, wherein the first polymer has a glass transition temperature higher than the second polymer. In a second aspect, the polymer binding material comprises a hydrophilic acrylic polymer, copolymer, or terpolymer. The conductive polymer compositions of the present invention may be used, for example, to make electrochemical sensors. Such sensors may be used, for example, in a variety of devices to monitor analyte amount or concentrations in subjects.

    Highly catalytic screen-printing ink
    4.
    发明授权
    Highly catalytic screen-printing ink 有权

    公开(公告)号：US07018568B2

    公开(公告)日：2006-03-28

    申请号：US10327506

    申请日：2002-12-19

    申请人： Michael J. Tierney

    发明人： Michael J. Tierney

    IPC分类号： H01B1/22

    CPC分类号： C09D11/52 ,  C08K3/04 ,  C08K3/08 ,  C09D11/101 ,  C09D11/30

    摘要： The invention is directed to conductive polymer compositions, catalytic ink compositions (e.g., for use in screen-printing), electrodes produced by deposition of an ink composition, methods of making, and methods of using thereof. An exemplary ink material comprises platinum black and/or platinum-on-carbon as the catalyst, graphite as a conducting material, a polymer binding material, and an organic solvent. The polymer binding material is typically a copolymer of hydrophilic and hydrophobic monomers. The conductive polymer compositions of the present invention can be used, for example, to make electrochemical sensors. Such sensors can be used in a variety of analyte monitoring devices to monitor analyte amount or concentrations in subjects, for example, glucose monitoring devices to monitor glucose levels in subjects with diabetes.

    Electrochemical sensor ink compositions, electrodes, and uses thereof
    5.
    发明授权
    Electrochemical sensor ink compositions, electrodes, and uses thereof 有权
    电化学传感器油墨组合物，电极及其用途

    公开(公告)号：US07731867B2

    公开(公告)日：2010-06-08

    申请号：US11656675

    申请日：2007-01-23

    申请人： Huawen Li ,  Michael J. Tierney

    发明人： Huawen Li ,  Michael J. Tierney

    IPC分类号： H01B1/22 ,  G01N27/327

    CPC分类号： C09D11/52 ,  C09D11/101 ,  C09D11/30 ,  G01N27/3271

    摘要： The invention is directed to conductive polymer compositions, catalytic ink compositions (e.g., for use in screen-printing), electrodes produced by deposition of an ink composition, as well as methods of making, and methods of using such compositions and electrodes. An exemplary ink material comprises a metal catalyst (e.g., platinum black and/or platinum-on-carbon), graphite as a conducting material, a polymer binding material, and an organic solvent. In one aspect, the polymer binding material comprises a polymer binder blend comprising first and second polymers, wherein the first polymer has a glass transition temperature higher than the second polymer. In a second aspect, the polymer binding material comprises a hydrophilic acrylic polymer, copolymer, or terpolymer. The conductive polymer compositions of the present invention may be used, for example, to make electrochemical sensors. Such sensors may be used, for example, in a variety of devices to monitor analyte amount or concentrations in subjects.

    摘要翻译： 本发明涉及导电聚合物组合物，催化油墨组合物（例如，用于丝网印刷），通过沉积油墨组合物制备的电极，以及制备方法，以及使用这种组合物和电极的方法。 示例性的油墨材料包括金属催化剂（例如，铂黑和/或铂 - 碳），作为导电材料的石墨，聚合物粘合材料和有机溶剂。 一方面，聚合物结合材料包括包含第一和第二聚合物的聚合物粘合剂共混物，其中第一聚合物的玻璃化转变温度高于第二聚合物。 在第二方面，聚合物粘合材料包括亲水丙烯酸聚合物，共聚物或三元共聚物。 本发明的导电聚合物组合物可用于例如制造电化学传感器。 这种传感器可以用于例如各种装置中以监测受试者中的分析物量或浓度。

    Methods for improving performance and reliability of biosensors
    6.
    发明申请
    Methods for improving performance and reliability of biosensors 审中-公开
    提高生物传感器性能和可靠性的方法

    公开(公告)号：US20100049022A1

    公开(公告)日：2010-02-25

    申请号：US12589237

    申请日：2009-10-19

    申请人： Norman A. Parris ,  Russell O. Potts ,  Michael J. Tierney ,  Christopher Uhegbu

    发明人： Norman A. Parris ,  Russell O. Potts ,  Michael J. Tierney ,  Christopher Uhegbu

    IPC分类号： A61B5/1477 ,  A61B5/145 ,  G06F19/00

    CPC分类号： A61B5/14532 ,  A61B5/14514 ,  A61B5/1486

    摘要： The present invention relates to a predictive-kinetic method for use with data processing of a sensor-generated signal, as well as, microprocessors and monitoring systems employing such a predictive-kinetic method. Data from a transient region of a signal is used with suitable models and curve-fitting methods to predict the signal that would be measured for the system at the completion of the reaction. The values resulting from data processing of sensor response using the methods of the present invention are less sensitive to measurement variables.

    摘要翻译： 本发明涉及一种用于传感器生成信号的数据处理的预测动力学方法，以及采用这种预测动力学方法的微处理器和监视系统。 来自信号的瞬态区域的数据与合适的模型和曲线拟合方法一起使用以预测在反应完成时将对系统测量的信号。 使用本发明的方法的传感器响应的数据处理产生的值对测量变量较不敏感。