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公开(公告)号：US11219367B2
公开(公告)日：2022-01-11
申请号：US16777252
申请日：2020-01-30
申请人： Reichert, Inc.
摘要： A spatially compact, lightweight positioning system for guiding an operator in positioning an ophthalmic instrument relative to an eye of a test subject has first and second light sources and an area detector spaced apart from a measurement axis of the instrument and from each other for providing positioning images which may be evaluated relative to stored calibration image information to determine current position of the instrument relative to the eye. The first and second light sources may fit within a lateral distance less than or equal to 25 mm. First and second illumination axes associated with the light sources may reside in a horizontal plane containing the measurement axis, and an observation axis of the area detector may reside in a vertical plane containing the measurement axis. The light sources and the area detector may be intersected by a plane which is normal to the measurement axis.
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公开(公告)号：US20210378503A1
公开(公告)日：2021-12-09
申请号：US16896506
申请日：2020-06-09
申请人： Reichert, Inc.
IPC分类号： A61B3/00
摘要： A headrest for an ophthalmic instrument facilitates fine positioning of the instrument relative to an eye of a test subject without the need to remove a contact element of the headrest from contact with the test subject's face. The ophthalmic instrument may be, for example, a rebound tonometer or a non-contact tonometer. The headrest includes a hollow bulbous contact element formed of resiliently deformable material, for example a thermoplastic elastomer (TPE) or silicone rubber. An outer surface of the contact element may have a spherical shape or a spheroidal shape when the contact element is not deformed.
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公开(公告)号：US08613704B2
公开(公告)日：2013-12-24
申请号：US13013102
申请日：2011-01-25
申请人： David A. Luce
发明人： David A. Luce
IPC分类号： A61B3/16
CPC分类号： A61B3/165
摘要： An ophthalmic instrument that discharges a fluid pulse to deform the cornea of a test subject is improved by reducing the working distance between a nosepiece or a discharge tube from which the fluid pulse is discharged and the eye of the test subject. The invention improves measurement repeatability and patient comfort.
摘要翻译： 通过减少流体脉冲被排出的鼻梁或放电管与受试者的眼睛之间的工作距离，可以改善排出流体脉冲以使测试对象的角膜变形的眼科仪器。 本发明提高了测量重复性和患者舒适度。
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公开(公告)号：US20090093698A1
公开(公告)日：2009-04-09
申请号：US12335566
申请日：2008-12-16
申请人： David A. Luce
发明人： David A. Luce
IPC分类号： A61B3/16
CPC分类号： A61B3/165
摘要： A method and apparatus for measuring intraocular pressure of an eye use an empirically derived function wherein an inward applanation pressure P1 and an outward applanation pressure P2 obtained during a corneal deformation cycle caused by a fluid pulse are separately weighted so as to minimize cornea-related influence on the intraocular pressure value calculated by the function. In one embodiment, the function is optimized, at least in part, to minimize change in calculated IOP between measurements made before surgical alteration of the cornea and measurements made after surgical alteration of the cornea.
摘要翻译： 用于测量眼睛眼压的方法和装置使用经验导出的功能，其中在由流体脉冲引起的角膜变形循环期间获得的向内压迫压力P1和向外压迫压力P2被分别加权，以便最小化与角膜相关的影响 对由功能计算出的眼内压值。 在一个实施例中，该功能被优化，至少部分地最小化在角膜手术改变之前进行的测量和角膜手术改变后进行的测量之间的计算IOP的变化。
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公开(公告)号：US20220015631A1
公开(公告)日：2022-01-20
申请号：US16932265
申请日：2020-07-17
申请人： Reichert, Inc.
发明人： David A. TAYLOR , Mary M. MURPHY
摘要： A contact tip for a contact tonometer has a body including a contact surface, and a coating applied to the contact surface. The coating includes a light-activated material and a biocompatible water soluble adhesive for adhering the coating to the contact surface. The water soluble adhesive dissolves upon contact with the corneal tear film during a tonometric measurement, thereby releasing the light-activated material into the tear film. The present disclosure further provides a single-use tonometer contact tip product which includes a sterilized contact tip having the mentioned contact surface coating, and an opaque package containing the sterilized contact tip.
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公开(公告)号：US09320430B2
公开(公告)日：2016-04-26
申请号：US12751281
申请日：2010-03-31
申请人： David A. Luce
发明人： David A. Luce
CPC分类号： A61B3/165 , A61B3/0025
摘要： In an ophthalmic instrument that directs a fluid pulse at a cornea to cause reversible deformation of the cornea and monitors the corneal deformation to generate a deformation signal, the shape of the deformation signal is analyzed with respect to deformation signal data from a statistical population of eyes to calculate a deformation signal score indicating a degree of probability that the deformation signal corresponds in shape to a normal deformation signal for normal eyes in the population. In calculating the deformation signal score, significant geometrical signal parameters are calculated and combined. The deformation signal score may be used as a basis to keep or discard intraocular pressure measurements in a non-contact tonometer, and/or as a basis to conduct further diagnostic screening.
摘要翻译： 在眼科仪器中，指示角膜上的流体脉冲引起角膜的可逆变形并监测角膜变形以产生变形信号，相对于来自统计学上的眼睛的变形信号数据分析变形信号的形状 计算出变形信号得分，其表示变形信号的形状对于群体中正常眼睛的正常变形信号的概率。 在计算变形信号得分时，计算并组合了重要的几何信号参数。 变形信号得分可以用作在非接触眼压计中保持或丢弃眼压测量的基础，和/或作为进一步诊断筛查的基础。
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公开(公告)号：US08885156B2
公开(公告)日：2014-11-11
申请号：US13128260
申请日：2010-08-24
CPC分类号： A61B3/101 , G01N21/31 , G01N21/33 , G01N21/43 , G01N2021/434
摘要： An apparatus comprises a spectrophotometer system configured to measure light absorbance by a tear sample, a refractometer system configured to measure refractive index of the tear sample, and an evaluation unit programmed to calculate an osmolarity of the tear sample based on the measured absorbance and refractive index and stored calibration curves. The spectrophotometer and refractometer systems may share a common prism contacted by the tear sample during measurement. The evaluation unit may be programmed to carry out steps of a method for determining osmolarity of the tear sample in accordance with the invention. The osmolarity of the tear sample may be used as an indicator in diagnosing dry eye.
摘要翻译： 一种装置包括分光光度计系统，其被配置为测量泪液样品的光吸收率，构造成测量泪液样品的折射率的折射计系统，以及基于测量的吸光度和折射率计算泪液样品的渗透压的评估单元 并存储校准曲线。 在测量期间，分光光度计和折射计系统可以共享与泪液样品接触的普通棱镜。 评估单元可以被编程为执行根据本发明的用于确定泪液样本的渗透压的方法的步骤。 泪液样本的渗透压可用作诊断干眼症的指标。
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公开(公告)号：US08226237B2
公开(公告)日：2012-07-24
申请号：US11860584
申请日：2007-09-25
IPC分类号： A61B3/02
CPC分类号： A61B3/032 , A61B3/0091 , A61B3/024 , A61B3/113
摘要： A system for delivering a touch sensitive screen task to a subject includes a touch sensitive display for presenting visual stimuli to a subject and for providing a response of the subject, hand position monitoring unit(s) for receiving input indicative of the position of a hand of the subject and for providing output signals representing said position and a controller/processor unit operatively coupled to the touch sensitive display unit and to the hand position monitoring unit(s) for receiving output signals from the hand position monitoring unit(s) and for processing the output signals to control the displaying of the visual stimuli on the touch sensitive display unit. A method for operating the system includes receiving from the subject signals representing a response of the subject to visual stimuli, receiving signals indicative of the position of the subject's hand and processing the signals to control the presenting of visual stimuli.
摘要翻译： 用于向对象传送触敏屏幕任务的系统包括用于向对象呈现视觉刺激并用于提供对象的响应的触敏显示器，用于接收指示手的位置的输入的手位置监视单元 并且用于提供表示所述位置的输出信号和可操作地耦合到触敏显示单元的控制器/处理器单元和用于接收来自手位置监视单元的输出信号的手位置监视单元，并且用于 处理输出信号以控制触敏显示单元上的视觉刺激的显示。 一种用于操作该系统的方法包括从所述对象接收表示所述受试者对视觉刺激的响应的信号，接收指示所述对象的手的位置的信号并处理所述信号以控制所述视觉刺激的呈现。
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公开(公告)号：US07665847B2
公开(公告)日：2010-02-23
申请号：US10556146
申请日：2004-05-05
申请人： Yair Alster , Omer Rafaeli , Edward Elikhis
发明人： Yair Alster , Omer Rafaeli , Edward Elikhis
IPC分类号： A61B3/10
CPC分类号： A61B3/024 , A61B3/0033 , A61B3/032 , G06F19/321
摘要： A method of providing an eye diagnosis. The method includes displaying stimuli to a patient, receiving indications of locations in which the stimuli were perceived by the patient, analyzing the spatial relationship between at least some of the received indicated locations and classifying the patient with regard to a retinal related disease, at least partially based on the spatial analysis.
摘要翻译： 提供眼睛诊断的方法。 所述方法包括向患者显示刺激，接收患者感觉到刺激的位置的指示，分析至少一些所接收到的指示位置之间的空间关系并且对视网膜相关疾病进行分类，至少 部分基于空间分析。
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10.发明授权Method and apparatus for measuring biomechanical characteristics of corneal tissue 失效测量角膜组织生物力学特性的方法和装置公开(公告)号：US07004902B2
公开(公告)日：2006-02-28
申请号：US10394833
申请日：2003-03-21
申请人： David A. Luce
发明人： David A. Luce
IPC分类号： A61B3/16
CPC分类号： A61B3/165 , A61B3/1005 , A61F2009/00872 , G06F19/00
摘要： A method for measuring a biomechanical characteristic of corneal tissue of a cornea comprises the steps of measuring a geometric parameter of the cornea, measuring hysteresis associated with deformation of the cornea, and evaluating the measured geometric parameter and hysteresis. In an ophthalmic system for practicing the method, a pachometer is used to measure corneal thickness and a tonometer is used to measure hysteresis, and the measurement data is supplied to a computer for evaluation. A related method for prequalifying LASIK patients comprises the steps of establishing a multi-dimensional space wherein a first dimension is a geometric corneal parameter and a second dimension is hysteresis associated with corneal deformation, measuring the geometric corneal parameter and hysteresis of the patient's cornea, registering the geometric corneal parameter and corneal hysteresis in a data point in the multi-dimensional space, and evaluating a location of the data point in the multi-dimensional space.
摘要翻译： 用于测量角膜角膜组织的生物力学特性的方法包括以下步骤：测量角膜的几何参数，测量与角膜变形相关的滞后，以及评估所测量的几何参数和滞后。 在用于实施该方法的眼科系统中，使用血压计来测量角膜厚度，并且使用眼压计来测量滞后，并将测量数据提供给计算机进行评估。 用于资格预测LASIK患者的相关方法包括建立多维空间的步骤，其中第一维度是几何角膜参数，第二维度是与角膜变形相关的滞后，测量患者角膜的几何角膜参数和滞后，登记 在多维空间中的数据点中的几何角膜参数和角膜滞后，以及评估多维空间中数据点的位置。
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