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公开(公告)号：US20230071061A1
公开(公告)日：2023-03-09
申请号：US17940080
申请日：2022-09-08
摘要： A phantom is disclosed containing fluorescence properties similar to anatomy that is needed to be visualized during surgical procedures. The phantom is created using substances including fluorophores that respond to UV light excitation to give visual cues of the phantom. The phantom can vary in phase and fluorescent properties depending on what it needs to simulate in the medical field with the purpose to help train users for surgical and diagnostic procedures, and develop, enhance, and calibrate imaging technology.
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公开(公告)号：US11576726B2
公开(公告)日：2023-02-14
申请号：US16368533
申请日：2019-03-28
IPC分类号： A61B34/10 , A61B5/00 , A61B34/00 , A61B90/00 , G01B9/02 , G01B9/02091 , A61B17/34 , A61B34/20 , G01N21/47
摘要： Systems and methods are provided for identifying a suitable surgical location and/or trajectory for proceeding with a surgical procedure based on local polarization-sensitive optical coherence tomography imaging (PS-OCT). PS-OCT images are obtained of a tissue region and are processed to provide a spatial map of anisotropic structure within the tissue region. The anisotropic structure is processed to determine one or more suitable surgical locations and/or trajectories for avoiding or reducing damage to local anisotropic tissue structure identified within the tissue region. The spatial map of the anisotropic structure is registered with pre-operative volumetric image data identifying anisotropic tissue structure within a second tissue region that is larger than the tissue region imaged by PS-OCT.
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公开(公告)号：US11567155B2
公开(公告)日：2023-01-31
申请号：US17026541
申请日：2020-09-21
发明人： Chad Tyler Harris , Geron Andre Bindseil , Alexander Gyles Panther , Jeff Alan Stainsby , Philip J. Beatty
IPC分类号： G01R33/389 , G01R33/38 , G01R33/3875 , G01R33/421 , G01R33/385
摘要： Described here are systems and methods for mitigating or otherwise removing the effects of short-term magnetic field instabilities caused by oscillations of the cold head in a cryogen-free magnet system used for magnetic resonance systems, such as magnetic resonance imaging (“MRI”) systems, nuclear magnetic resonance (“NMR”) systems, or the like.
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公开(公告)号：US11567152B2
公开(公告)日：2023-01-31
申请号：US17383020
申请日：2021-07-22
发明人： Ian Robert Oliphant Connell , Gilbert Thevathasan , William Wai-Leung Lau , Alexander Gyles Panther
IPC分类号： G01R31/00 , G01R33/34 , A61B5/055 , G01R33/341
摘要： A head coil assembly includes a housing with a lower portion, an upper portion, a left portion, and a right portion, wherein each portion includes two or more radio-frequency (RF) coils, wherein the portions are sized and shaped to adjustably conform to a curvature of the subject's head for magnetic resonance (MR) imaging of the subject's head placed inside the housing, wherein the portions are operable to transition from an open position where the portions are sufficiently apart from each other to a closed position where the portions are adjusted to tighten a wrap around the subject's head along the curvature, and wherein the two or more RF coils in each portion are disposed in such manner that when the portions are operated to transition from the open position to the closed position, the RF coils of each portion remain decoupled to each other even along edges of each portion.
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5.发明授权公开(公告)号：US11474176B2
公开(公告)日：2022-10-18
申请号：US17331378
申请日：2021-05-26
发明人： Ian Connell , Chad Harris , Geron Bindseil , Andrew T. Curtis
IPC分类号： G01R33/3875 , G01R33/54 , G01R33/381
摘要： A method, device, and system for reducing inhomogeneity in an imaging magnetic field during magnetic resonance imaging is described. The method includes generating a corrective magnetic field during imaging, the corrective magnetic field having a first magnetic field component and a second magnetic field component with a phase separation therebetween. The first and second components are generated according to a stability parameter decomposed from a stability field that correct an instability identified within the imaging magnetic field.
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公开(公告)号：US11428764B2
公开(公告)日：2022-08-30
申请号：US17162051
申请日：2021-01-29
IPC分类号： G01R33/3815 , H01F6/04 , G01R33/38
摘要： A magnetic resonance imaging (MRI) system includes a set of magnet coils for generating a magnetic field. The set of magnet coils are composed of a superconducting material. The system further includes a mechanical cryocooler in thermal contact with the set of magnet coils and operable to reduce and maintain a temperature of the set of magnet coils below a transition temperature of the superconducting material, and an energy storage device coupled to the set of magnet coils. The energy storage device may be capable of receiving and storing energy dissipated from the set of magnet coils during rapid shutdown of the set of magnet coils. The system may also include a controller coupled to the energy storage device. The controller may be programmed to recharge the set of magnet coils using the energy stored in the energy storage device during the rapid shutdown of the set of magnet coils.
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公开(公告)号：US20220236148A1
公开(公告)日：2022-07-28
申请号：US17658734
申请日：2022-04-11
摘要： The present invention provides a system and method for collection, storage and processing of tissues and cells. The system includes a collection container with chambers for storing and processing tissues, which are controllably separated and maintain a physiologic environment for the tissues. The system also includes a fluidic device for isolating target cells of interest. The method includes receiving the tissue into a collection chamber, transferring the tissue to a processing chamber, dissociating the tissue into single cells, and passing the single cells to a device for isolating one or more target cells.
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公开(公告)号：US20220167868A1
公开(公告)日：2022-06-02
申请号：US17651392
申请日：2022-02-16
发明人： Gal SELA , Neil Jeffrey WITCOMB
摘要： The navigation systems and methods facilitate aligning a tool in relation to a trajectory in real-time to receive input data from a pre-operative plan image, at least one multi-modal image, and at least one real-time multi-modal image; interactively track at least one neural fiber, whereby interactively tracked fiber data is obtainable; automatically generate output data by way of data transformation using the input data and the interactively tracked neural fiber data; and transmit the output data to at least one of: at least one display device for rendering at least one real-time interactive navigation display for facilitating neural navigation, and at least one drive device for positioning at least one tracking device in relation to the tool in real-time, whereby real-time alignment data is achievable, and whereby at least one neurological structure is preservable.
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公开(公告)号：US11310477B2
公开(公告)日：2022-04-19
申请号：US16703179
申请日：2019-12-04
发明人： William La , Siu Wai Jacky Mak
IPC分类号： H04N13/239 , G02B27/10 , G02B3/14 , G02B27/14 , G02B27/00 , H04N13/156 , A61B90/00 , H04N13/296
摘要： An exoscope with enhanced depth of field imaging is provided. The exoscope includes first and second sets of optical devices, the first set having a fixed image plane, the second set having a variable image plane adjacent the fixed image plane of the first set. The second set includes at least one variable device configured to change the position of the variable image plane. A beamsplitter splits light from a combined optical path of the first and second set to respective image devices of the first and second set of optical devices. A controller controls the at least one variable device to change the position of the variable image plane relative to the fixed image plane, combines images acquired by the respective image devices, and controls a display device to render a combined image.
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公开(公告)号：US20220079442A1
公开(公告)日：2022-03-17
申请号：US17190897
申请日：2021-03-03
发明人： Cameron Piron , Michael Wood , Murugathas Yuwaraj , Alex Panther , Nishanthan Shanmugaratnam , William Lau , Monroe M. Thomas , Gal Sela , Joshua Richmond , Wes Hodges , Simon Alexander , David Gallop
摘要： Insertable imaging devices, and methods of use thereof in minimally invasive medical procedures, are described. In some embodiments, insertable imaging devices are described that can be introduced and removed from an access port without disturbing or risking damage to internal tissue. In some embodiments, imaging devices are integrated into an access port, thereby allowing imaging of internal tissues within the vicinity of the access port, while, for example, enabling manipulation of surgical tools in the surgical field of interest. In other embodiments, imaging devices are integrated into an imaging sleeve that is insertable into an access port. Several example embodiments described herein provide imaging devices for performing imaging within an access port, where the imaging may be based one or more imaging modalities that may include, but are not limited to, magnetic resonance imaging, ultrasound, optical imaging such as hyperspectral imaging and optical coherence tomography, and electrically conductive measurements.
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