SYSTEM AND METHODS OF CONCURRENT WHITE LIGHT AND VISIBLE FLUORESCENCE VISUALIZATION

    公开(公告)号:US20240085684A1

    公开(公告)日:2024-03-14

    申请号:US18467564

    申请日:2023-09-14

    IPC分类号: G02B21/36 G02B21/02 G02B21/16

    摘要: A visualization system and methods for simultaneously visualizing white light and visible fluorescent light, the visualization involving an illumination system and an imaging system operable with the illumination system. The illumination system has a light source produces illumination light (white light and fluorescence excitation light), an optical notch rejection filter to remove light having peak fluorescence excitation wavelengths from the illumination light, and illumination optics to at least one of deliver and condense the filtered illumination light. The imaging system has imaging optics, a fluorescence excitation light removal filter to remove excitation light from the imaged light, a beam splitter to split the filtered images light into a first beam (white light), and a second beam (fluorescent imaging light), an optical notch rejection filter to ensure that light, having peak fluorescence emission wavelengths of a fluorophore, does not reach a white light camera, an optical notch pass filter to pass only the fluorescent imaging light component, a camera to image the white light; and another camera to image the fluorescent light.

    Gradient coil apparatus and methods for MRI

    公开(公告)号:US11821970B2

    公开(公告)日:2023-11-21

    申请号:US17645108

    申请日:2021-12-20

    IPC分类号: G01R33/385

    CPC分类号: G01R33/3856 G01R33/3858

    摘要: A coil apparatus and methods for magnetic resonance imaging involving a wire winding, the wire winding having at least one of: a hollow cross-section wire and a solid cross-section wire, the solid cross-section wire having at least one of: a solid small cross-section wire and a solid large cross-section wire, the solid large cross-section wire having a thickness greater than that of the solid small cross-section wire, and the solid small cross-section wire disposed in one of adjacent and proximate at least one of the hollow cross-section wire and the solid large cross-section wire, whereby at least one of current density, winding density, and heat extraction are increasable.

    Dynamic B
    9.
    发明授权

    公开(公告)号:US11686795B2

    公开(公告)日:2023-06-27

    申请号:US17369924

    申请日:2021-07-07

    CPC分类号: G01R33/3875 G01R33/4828

    摘要: A fat saturation method for a magnetic resonance imaging system having a main magnet providing a magnetic field B0 The method includes: driving a shim coil assembly with a first set of shimming currents to sufficiently alter a B0 field inhomogeneity of the magnetic field B0 within a region that includes a first imaging volume of interest such that water saturation inside the region is reduced from before the first set of shimming currents are applied; applying a fat saturation pulse to the region; identifying the first imaging volume of interest from the region; driving the shim coil assembly with a second set of shimming currents to alter the B0 field inhomogeneity of the magnetic field B0 within the first imaging volume of interest such that the B0 field inhomogeneity within the first imaging volume of interest is reduced; and obtaining magnetic resonance signals from the first imaging volume of interest.

    Integrated active detuning for magnetic resonance imaging

    公开(公告)号:US11668775B2

    公开(公告)日:2023-06-06

    申请号:US17362005

    申请日:2021-06-29

    IPC分类号: G01R33/36 G01R33/34

    摘要: A coil assembly includes: a radio frequency (RF) coil operable to be placed over a portion of a subject; a quarter-wave transformer coupled to the RF coil and configured to transform a characteristic impedance of the RF coil; and a diode placed behind the quarter-wave transformer and away from the RF coil, wherein the diode is operable to: (i) when the diode is forward biased, the diode turns the quarter-wave transformer into an open circuit such that the power amplifier drives the RF coil with sufficient electrical power for the RF coil to transmit an RF pulse into the portion of the subject; and (ii) when the diode is provided zero or revers bias, the diode turns the quarter-wave transformer into a short circuit such that the RF coil is detuned from a Lamor frequency of nuclei of interest immersed in the main magnet.