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公开(公告)号：US09828444B2
公开(公告)日：2017-11-28
申请号：US14652093
申请日：2013-12-04
IPC分类号： C08L5/08 , C08B37/00 , D01F9/00 , C08B37/08 , C09D105/08
CPC分类号： C08B37/0027 , C08B37/003 , C09D105/08 , D01F9/00
摘要： A poly-[1-4]-D-glucosamine derivative comprising [1-4]-D-glucosamine recurring units and comprising a fluoropolyether chain bound to the nitrogen atom in the C-2 position of at least one of the [1-4]-D-glucosamine recurring units.
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公开(公告)号：US07115588B2
公开(公告)日：2006-10-03
申请号：US10194740
申请日：2002-07-12
CPC分类号： A61K31/726 , A61K9/0014 , A61K9/7007 , A61K31/715 , A61K31/722 , A61K31/737 , C08B37/0027 , C08B37/003 , Y10S514/93
摘要： The present invention relates to compositions comprising semi-crystalline β-1-4-N-acetylglucosamine polymers (p-GlcNac) and methods utilizing such polymers modulation of vascular structure and/or function. The compositions and methods disclosed are useful for stimulating, in a p-GlcNac concentration-dependent manner, endothelin-1 release, vasoconstriction, and/or reduction in blood flow out of a breached vessel, as well as for contributing to or effecting cessation of bleeding. The methods of the present invention comprise topical administration of materials comprising semi-crystalline p-GlcNac polymers that are free of proteins, and substantially free of single amino acids as well as other organic and inorganic contaminants, and whose constituent monosaccharide sugars are attached in a β-1-4 conformation.
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公开(公告)号：US5663254A
公开(公告)日：1997-09-02
申请号：US445865
申请日：1995-05-22
申请人： Yuan-Chuan Lee , Jian-Qiang Fan
发明人： Yuan-Chuan Lee , Jian-Qiang Fan
CPC分类号： C08B37/0027 , C07H3/06 , C12P19/14
摘要： Neoglycoconjugates and new intermediates for the synthesis thereof are synthesized by use of Endo-.beta.-N-acetylglucosaminidase from Arthrobacter protophormiae (Endo-A) in a medium containing an organic solvent.
摘要翻译： 通过使用来自节杆菌（Endo-A）的Endo-β-N-乙酰氨基葡萄糖苷酶在含有机溶剂的培养基中合成神经覆盖物及其合成的新中间体。
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公开(公告)号：US20150045221A1
公开(公告)日：2015-02-12
申请号：US14511272
申请日：2014-10-10
申请人： FYTOFEND S.A.
CPC分类号： A01N43/16 , A01N43/40 , A01N43/42 , A01N43/56 , A01N47/12 , A01N47/24 , A01N57/10 , A01N59/00 , A01N59/02 , C07H3/06 , C07H5/06 , C08B37/0024 , C08B37/0027 , C08B37/003 , C08B37/0045 , Y02A40/17 , A01N43/653 , A01N57/12 , A01N2300/00
摘要： The present invention generally relates to new plant elicitor compositions, and the use of these compositions in agricultural applications, more particularly to protect plants against (infection by) plant pathogens and the corresponding methods of, and uses in, the protection of plants and crops by application of these compositions.
摘要翻译： 本发明一般涉及新的植物诱发剂组合物，以及这些组合物在农业应用中的用途，更具体地说是通过以下方式保护植物免受植物病原体的感染（植物病原体的感染）和植物和作物的相应方法和用途 这些组合物的应用。
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5.发明授权Compositions and methods for modulation of vascular structure and/or function 有权用于调节血管结构和/或功能的组合物和方法公开(公告)号：US08859528B2
公开(公告)日：2014-10-14
申请号：US13932860
申请日：2013-07-01
IPC分类号： A01N43/04 , A61K31/70 , A61K31/722 , C08B37/08 , A61K31/726 , A61K31/715 , C08B37/00 , A61K31/737
CPC分类号： A61K31/726 , A61K9/0014 , A61K9/7007 , A61K31/715 , A61K31/722 , A61K31/737 , C08B37/0027 , C08B37/003 , Y10S514/93
摘要： The present invention relates to compositions comprising semi-crystalline β-1-4-N-acetylglucosamine polymers (p-GlcNac) and methods utilizing such polymers modulation of vascular structure and/or function. The compositions and methods disclosed are useful for stimulating, in a p-GlcNac concentration-dependent manner, endothelin-1 release, vasoconstriction, and/or reduction in blood flow out of a breached vessel, as well as for contributing to or effecting cessation of bleeding. The methods of the present invention comprise topical administration of materials comprising semi-crystalline p-GlcNac polymers that are free of proteins, and substantially free of single amino acids as well as other organic and inorganic contaminants, and whose constituent monosaccharide sugars are attached in a β-1-4 conformation.
摘要翻译： 本发明涉及包含半结晶和1-84-N-乙酰葡糖胺聚合物（p-GlcNac）的组合物以及利用这种聚合物调节血管结构和/或功能的方法。 所公开的组合物和方法可用于以p-GlcNac浓度依赖性方式刺激内皮素-1释放，血管收缩和/或从破裂的血管中减少血流，以及促进或停止 流血的。 本发明的方法包括局部施用包含不含蛋白质的半结晶p-GlcNac聚合物的材料，并且基本上不含单一氨基酸以及其它有机和无机污染物，并且其构成单糖糖连接在 ＆bgr; -1-4构象。
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公开(公告)号：US07041657B2
公开(公告)日：2006-05-09
申请号：US09781182
申请日：2001-02-12
IPC分类号： A01N43/04 , A61K31/715
CPC分类号： A61K31/726 , A61K9/0014 , A61K9/7007 , A61K31/715 , A61K31/722 , A61K31/737 , C08B37/0027 , C08B37/003 , Y10S514/93
摘要： The present invention relates to compositions comprising semi-crystalline β-1-4-N-acetylglucosamine polymers (p-GlcNac) and methods utilizing such polymers modulation of vascular structure and/or function. The compositions and methods disclosed are useful for stimulating, in a p-GlcNac concentration-dependent manner, endothelin-1 release, vasoconstriction, and/or reduction in blood flow out of a breached vessel, as well as for contributing to or effecting cessation of bleeding. The methods of the present invention comprise topical administration of materials comprising semi-crystalline p-GlcNac polymers that are free of proteins, and substantially free of single amino acids as well as other organic and inorganic contaminants, and whose constituent monosaccharide sugars are attached in a β-1-4 conformation.
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公开(公告)号：US06534294B1
公开(公告)日：2003-03-18
申请号：US09723657
申请日：2000-11-28
申请人： Jin Woo Lee , Walter G. Yeomans , Alfred L. Allen , Fang Deng , Richard A. Gross , David L. Kaplan
发明人： Jin Woo Lee , Walter G. Yeomans , Alfred L. Allen , Fang Deng , Richard A. Gross , David L. Kaplan
IPC分类号： C12P1904
CPC分类号： C08B37/0027 , C08B37/003 , C12P19/04 , C12P19/26
摘要： A method of producing biosynthetic copolymers comprising glucose and glucose analogs is provided. Glucose:glucose analog copolymers such as glucose:glucosamine, glucose:N-acetylglucosamine and glucose:glucosamine:N-acetylglucosamine are also provided.
摘要翻译： 提供了包含葡萄糖和葡萄糖类似物的生物合成共聚物的生产方法。 葡萄糖：葡萄糖类似物共聚物如葡萄糖：葡糖胺，葡萄糖：N-乙酰葡糖胺和葡萄糖：葡糖胺：N-乙酰氨基葡萄糖。
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8.发明申请Compositions and Methods For Modulation of Vascular Structure and/or Function 审中-公开用于调节血管结构和/或功能的组合物和方法公开(公告)号：US20150118281A1
公开(公告)日：2015-04-30
申请号：US14479196
申请日：2014-09-05
IPC分类号： A61K31/726 , A61K9/00 , A61K9/70
CPC分类号： A61K31/726 , A61K9/0014 , A61K9/7007 , A61K31/715 , A61K31/722 , A61K31/737 , C08B37/0027 , C08B37/003 , Y10S514/93
摘要： The present invention relates to compositions comprising semi-crystalline β-1-4-N-acetylglucosamine polymers (p-GlcNac) and methods utilizing such polymers modulation of vascular structure and/or function. The compositions and methods disclosed are useful for stimulating, in a p-GlcNac concentration-dependent manner, endothelin-1 release, vasoconstriction, and/or reduction in blood flow out of a breached vessel, as well as for contributing to or effecting cessation of bleeding. The methods of the present invention comprise topical administration of materials comprising semi-crystalline p-GlcNac polymers that are free of proteins, and substantially free of single amino acids as well as other organic and inorganic contaminants, and whose constituent monosaccharide sugars are attached in a β-1-4 conformation.
摘要翻译： 本发明涉及包含半结晶和1-84-N-乙酰葡糖胺聚合物（p-GlcNac）的组合物以及利用这种聚合物调节血管结构和/或功能的方法。 所公开的组合物和方法可用于以p-GlcNac浓度依赖性方式刺激内皮素-1释放，血管收缩和/或从破裂的血管中减少血流，以及促进或停止 流血的。 本发明的方法包括局部施用包含不含蛋白质的半结晶p-GlcNac聚合物的材料，并且基本上不含单一氨基酸以及其它有机和无机污染物，并且其构成单糖糖连接在 ＆bgr; -1-4构象。
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公开(公告)号：US20130302437A1
公开(公告)日：2013-11-14
申请号：US13980432
申请日：2012-01-24
IPC分类号： A01N43/16 , A01N59/00 , A01N43/42 , A01N43/40 , A01N57/10 , A01N43/56 , A01N59/02 , A01N47/12
CPC分类号： A01N43/16 , A01N43/40 , A01N43/42 , A01N43/56 , A01N47/12 , A01N47/24 , A01N57/10 , A01N59/00 , A01N59/02 , C07H3/06 , C07H5/06 , C08B37/0024 , C08B37/0027 , C08B37/003 , C08B37/0045 , Y02A40/17 , A01N43/653 , A01N57/12 , A01N2300/00
摘要： The present invention generally relates to new plant elicitor compositions, and the use of these compositions in agricultural applications, more particularly to protect plants against (infection by) plant pathogens and the corresponding methods of, and uses in, the protection of plants and crops by application of these compositions.
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10.发明申请COMPOSITIONS AND METHODS FOR MODULATION OF VASCULAR STRUCTURE AND/OR FUNCTION 有权用于调节血管结构和/或功能的组合物和方法公开(公告)号：US20100323986A1
公开(公告)日：2010-12-23
申请号：US12816957
申请日：2010-06-16
IPC分类号： A61K31/715 , A61P9/00 , A61P9/14
CPC分类号： A61K31/726 , A61K9/0014 , A61K9/7007 , A61K31/715 , A61K31/722 , A61K31/737 , C08B37/0027 , C08B37/003 , Y10S514/93
摘要： The present invention relates to compositions comprising semi-crystalline β-1-4-N-acetylglucosamine polymers (p-GlcNac) and methods utilizing such polymers modulation of vascular structure and/or function. The compositions and methods disclosed are useful for stimulating, in a p-GlcNac concentration-dependent manner, endothelin-1 release, vasoconstriction, and/or reduction in blood flow out of a breached vessel, as well as for contributing to or effecting cessation of bleeding. The methods of the present invention comprise topical administration of materials comprising semi-crystalline p-GlcNac polymers that are free of proteins, and substantially free of single amino acids as well as other organic and inorganic contaminants, and whose constituent monosaccharide sugars are attached in a β-1-4 conformation.
摘要翻译： 本发明涉及包含半结晶和1-84-N-乙酰葡糖胺聚合物（p-GlcNac）的组合物以及利用这种聚合物调节血管结构和/或功能的方法。 所公开的组合物和方法可用于以p-GlcNac浓度依赖性方式刺激内皮素-1释放，血管收缩和/或从破裂的血管中减少血流，以及促进或停止 流血的。 本发明的方法包括局部施用包含不含蛋白质的半结晶p-GlcNac聚合物的材料，并且基本上不含单一氨基酸以及其它有机和无机污染物，并且其构成单糖糖连接在 ＆bgr; -1-4构象。
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