Amino substituted-4-t-butylphthalic acid esters
    1.
    发明授权
    Amino substituted-4-t-butylphthalic acid esters 失效
    氨基取代-4-叔丁基邻苯二甲酸酯

    公开(公告)号:US4078142A

    公开(公告)日:1978-03-07

    申请号:US700583

    申请日:1976-06-28

    申请人: Robert G. Keske

    发明人: Robert G. Keske

    IPC分类号: C08G73/10 C07C101/66

    CPC分类号: C08G73/1067

    摘要: Novel amino-substituted derivatives of 4-t-butylphthalic anhydride are used as monomers to produce novel polyimides with improved solubility characteristics. Increased solubility in organic solvents permits these polyimides to be used in coating applications where structurally similar polyimides could not otherwise be used.

    摘要翻译: 使用4-叔丁基邻苯二甲酸酐的新型氨基取代衍生物作为单体以产生具有改善的溶解度特征的新型聚酰亚胺。 在有机溶剂中增加的溶解性允许这些聚酰亚胺被用于涂料应用,其中结构上相似的聚酰亚胺不能被使用。

    Aromatic compounds and their manufacture
    2.
    发明授权
    Aromatic compounds and their manufacture 失效
    芳香族化合物及其制造

    公开(公告)号:US4371694A

    公开(公告)日:1983-02-01

    申请号:US197772

    申请日:1980-07-01

    摘要: Compounds of Formula I or Formula II ##STR1## where A is an electron withdrawing group and B is a secondary or tertiary amino group or the group OD where D is H, aryl or an aliphatic group are made by reacting a corresponding compound of Formula Ia or Formula IIa ##STR2## in a solvent with a reagent selected from organic primary and secondary amines and compounds of the formula MOD where M is an alkali metal and A and D are as defined above. In this process the nitro group and the group B in Formula I and Ia are in the 2- or 4- position and the compounds of Formula I, Ia, II and IIa may optionally be further substituted. Preferably a primary or secondary amine is reacted with a compound of formula Ia, preferably using dimethylformamide as solvent. The process can result in the production of novel compounds, including (1) Compounds of Formula III wherein each group A is CO.sub.2 H or an alkali metal, amine or ammonium salt thereof or the two groups A together form a carboxylic anhydride group and B is in the 2- or 4-position and is OD, where D is hydrogen or an aliphatic group or is a secondary or tertiary amine group, (2) compounds of Formula IV ##STR3## where B is the group OD or the group NR.sub.2 R.sub.3 and wherein at least one of R.sub.1 and D or at least one of R.sub.1, R.sub.2 and R.sub.3 comprise a solubilizing group containing a primary amino, carboxylic, sulphonate or phosphate ester group in the form of an alkali metal, amine or ammonium salt or is a polyalkylene oxide group, the compounds optionally being further substituted.

    摘要翻译: PCT No.PCT / GB79 / 00183 Sec。 371日期1980年7月1日 102(e)日期1980年7月1日PCT申请日1979年11月7日PCT公布。 出版物WO80 / 00963 日期:1980年5月15日。式I或式II的化合物,其中A是吸电子基团,B是仲或叔氨基或基团OD,其中D是H,芳基或脂族基团,是通过 式Ia或式IIa的相应化合物在溶剂中与选自有机伯胺和仲胺的试剂和式MOD化合物,其中M是碱金属,A和D如上所定义。 在该方法中,式I和Ia中的硝基和B基团在2-或4-位,式I,Ia,II和IIa的化合物可以任选地被进一步取代。 优选地,伯胺或仲胺与式Ia化合物反应,优选使用二甲基甲酰胺作为溶剂。 该方法可以产生新化合物,其包括(1)式III化合物其中每一组A为CO 2 H或其碱金属,胺或铵盐或两组A一起形成羧酸酐基团 B为2-或4-位,其中D为氢或脂族基团或二胺或叔胺基团,(2)式IV化合物其中B为基团OD或 基团NR 2 R 3,并且其中R 1和D中的至少一个或R 1,R 2和R 3中的至少一个包含含有碱金属,胺或铵盐形式的伯氨基,羧酸,磺酸酯或磷酸酯基团的增溶基团 或者是聚环氧烷基,该化合物任选进一步被取代。

    4-(Monoalkylamino)benzene polycarboxylic acids
    5.
    发明授权
    4-(Monoalkylamino)benzene polycarboxylic acids 失效
    4-(单烷基氨基)苯多元羧酸

    公开(公告)号:US4245120A

    公开(公告)日:1981-01-13

    申请号:US836945

    申请日:1977-09-27

    IPC分类号: C07C101/66

    CPC分类号: Y10S514/824

    摘要: This disclosure describes the monoalkylaminobenzene multi-carboxylic acids, derivatives and salts thereof useful as hypolipidemic and anti-atherosclerotic agents.

    摘要翻译: 本公开描述了可用作降血脂和抗动脉粥样硬化剂的单烷基氨基苯多羧酸,其衍生物和盐。

    4-(Monoalkylamino) benzene polycarboxylic acids
    6.
    发明授权
    4-(Monoalkylamino) benzene polycarboxylic acids 失效
    4-(单烷基氨基)苯多元羧酸

    公开(公告)号:US4245119A

    公开(公告)日:1981-01-13

    申请号:US959537

    申请日:1978-11-13

    IPC分类号: C07C101/66

    CPC分类号: Y10S514/824

    摘要: This disclosure describes the monoalkylaminobenzene multi-carboxylic acids, derivatives and salts thereof useful as hypolipidemic and anti-atherosclerotic agents.

    摘要翻译: 本公开描述了可用作降血脂和抗动脉粥样硬化剂的单烷基氨基苯多羧酸,其衍生物和盐。

    N-(carboxymethoxy-benzylidine)carboxy anilines and pharmaceutical
compositions thereof
    8.
    发明授权
    N-(carboxymethoxy-benzylidine)carboxy anilines and pharmaceutical compositions thereof 失效
    N-(羧基甲氧基 - 亚苄基)羧基苯胺及其药物组合物

    公开(公告)号:US4046916A

    公开(公告)日:1977-09-06

    申请号:US529464

    申请日:1974-12-04

    摘要: Novel products having analgesic and antipyretic activity are provided having the formula:R -- Z -- R'in which each of R and R', which may be the same or different, represents a phenyl or pyridyl radical which is optionally substituted by at least one substituent selected from a halogen atom, --NO.sub.2, --CONH.sub.2 --, --OC.sub.2 H.sub.5, OCH.sub.3, --CH.sub.3, --COOC.sub.2 H.sub.5, --COOCH.sub.3, --COOH and --OCH.sub.2 --COOH radical; Z represents a radical selected from --CH=N-- and >CH--NH-- in which the radical >CH-- of said amino group forms part of a heterocyclic structure of the formula: ##STR1## in which the two carbon atoms connected by a double bond form part of the radical R or R'. Specific compounds include 2-(2'-carboxamido-anilino)-o-phthalide and 2-(2' or 4'-ethoxy-anilino)-o-phthalide.

    摘要翻译: 提供具有镇痛和解热活性的新产品,具有下式: