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公开(公告)号：US20240149280A1
公开(公告)日：2024-05-09
申请号：US18407827
申请日：2024-01-09
发明人： Stephen B. Kessler , T. David Marro
CPC分类号： B04B11/04 , B04B11/02 , B04B11/082 , B04B2005/0464
摘要： An apparatus for separating cell suspension material into centrate and concentrate, includes a single use structure (178, 240, 250) releasably positioned in a cavity in a solid wall rotatable centrifuge bowl (172). The bowl and portions of single use structure rotate about an axis (174). A stationary inlet feed tube (184), a centrate discharge tube (212) and a concentrate discharge tube (230) extend along the axis of the rotating single use structure. A centrate centripetal pump (208) is in fluid connection with the centrate discharge tube. A concentrate centripetal pump (216) is in fluid connection with the concentrate discharge tube. A controller (274) operates responsive to sensors (264, 270) in respective centrate and concentrate discharge lines (262, 268), to control flow rates of a concentrate pump (272) and a centrate pump (266) to produce output flows of cell concentrate and generally cell free centrate.
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公开(公告)号：US20240131529A1
公开(公告)日：2024-04-25
申请号：US18396084
申请日：2023-12-26
发明人： Stephen B. Kessler , T. David Marro
CPC分类号： B04B11/04 , B04B11/02 , B04B11/082 , B04B2005/0464
摘要： An apparatus for separating cell suspension material into centrate and concentrate, includes a single use structure (178, 240, 250) releasably positioned in a cavity in a solid wall rotatable centrifuge bowl (172). The bowl and portions of single use structure rotate about an axis (174). A stationary inlet feed tube (184), a centrate discharge tube (212) and a concentrate discharge tube (230) extend along the axis of the rotating single use structure. A centrate centripetal pump (208) is in fluid connection with the centrate discharge tube. A concentrate centripetal pump (216) is in fluid connection with the concentrate discharge tube. A controller (274) operates responsive to sensors (264, 270) in respective centrate and concentrate discharge lines (262, 268), to control flow rates of a concentrate pump (272) and a centrate pump (266) to produce output flows of cell concentrate and generally cell free centrate.
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公开(公告)号：US11377792B2
公开(公告)日：2022-07-05
申请号：US17511501
申请日：2021-10-26
发明人： Feng Ling
IPC分类号： B01D1/00 , D21C11/00 , B01D1/26 , B01D3/14 , B01D3/38 , B04B11/02 , B04B11/08 , C05F5/00 , C07G1/00 , C08B1/08 , C08L5/14 , C12F3/10 , D21C9/00 , B01D3/00
摘要： Provided herein are compositions and processes concerning efficient downstream processing of products derived from organic acids pretreatment of plant materials.
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公开(公告)号：US11065629B2
公开(公告)日：2021-07-20
申请号：US16433180
申请日：2019-06-06
发明人： Stephen B. Kessler , T. David Marro
摘要： An apparatus for separating cell suspension material into centrate and concentrate, includes a single use structure (178, 240, 250) releasably positioned in a cavity in a solid wall rotatable centrifuge bowl (172). The bowl and portions of single use structure rotate about an axis (174). A stationary inlet feed tube (184), a centrate discharge tube (212) and a concentrate discharge tube (230) extend along the axis of the rotating single use structure. A centrate centripetal pump (208) is in fluid connection with the centrate discharge tube. A concentrate centripetal pump (216) is in fluid connection with the concentrate discharge tube. A controller (274) operates responsive to sensors (264, 270) in respective centrate and concentrate discharge lines (262, 268), to control flow rates of a concentrate pump (272) and a centrate pump (266) to produce output flows of cell concentrate and generally cell free centrate.
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公开(公告)号：US11033911B2
公开(公告)日：2021-06-15
申请号：US16003659
申请日：2018-06-08
发明人： Stephen B Kessler , T David Marro
IPC分类号： B04B11/04 , B04B11/02 , B04B15/08 , B04B5/04 , B04B11/08 , B04B1/06 , C12M1/12 , C12M1/26 , C12M1/00
摘要： A method and apparatus for separating cell suspension into centrate and concentrate includes a solid wall rotatable centrifuge bowl (82). A single use rotatable core (88) is positioned in the bowl and bounds a cavity (90) which serves as a separation chamber. The bowl rotates about an axis (84). An inlet tube (92) and an outlet tube (102) extend along the axis in the bowl cavity. The centripetal pump (98) in the cavity is in connection with the outlet tube. The centrate discharge pump (120) is in connection with the outlet tube. A pressure damping reservoir (122) is fluidly connected between the outlet tube and the discharge pump. At least one control circuit (142) is operative to control the apparatus to maintain a positive pressure above atmospheric pressure within the cavity, so as to maintain the cell suspension away from at least one seal (106) that bounds the interior of the cavity.
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公开(公告)号：US10562040B2
公开(公告)日：2020-02-18
申请号：US16391023
申请日：2019-04-22
发明人： Jung-Ming Wu
摘要： A centrifugal filtering device includes a centrifugal drum and a rotary filter. The centrifugal drum has a receiving space for accommodating the source fluid. The rotary filter rotatably mounted in the receiving space includes a filter body and a filtrate discharge pipe. The filter body includes a filter cartridge defining a filtrate-collecting space. The filtrate discharge pipe connecting the filter body is communicative in space with the filtrate-collecting space. By rotating at least one of the centrifugal drum and the rotary filter, the source fluid is driven to generate a vortex by a centrifugal force. The centrifugal force drives the source fluid to form a heavy-phase fluid hitting the centrifugal drum and a light-phase fluid approaching the filter cartridge. The light-phase fluid passes the filter cartridge and then reaches the filtrate-collecting space as a filtrate, and the filtrate is exhausted via the filtrate discharge pipe of the centrifugal filtering device.
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公开(公告)号：US20170314352A1
公开(公告)日：2017-11-02
申请号：US15582303
申请日：2017-04-28
CPC分类号： E21B21/065 , B04B1/2016 , B04B3/04 , B04B9/08 , B04B9/10 , B04B11/08
摘要： A vertical cuttings dryer (“VCD”) can be used to separate solid particulate from entrained liquid. In some examples, the VCD includes a screen mounted coaxially with an internal wiper housing that carriers a wiper sweeping out an annular space between the screen and wiper housing. The VCD may have a first motor connected through drive shaft to the screen and a second motor connect through a separate drive shaft to the wiper housing. A controller can independently control the speed of the first motor and the second motor to independently a magnitude of centrifugal force applied to material being processed as well as a residence time of the material being processed in the annular space.
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公开(公告)号：US09358554B2
公开(公告)日：2016-06-07
申请号：US13505902
申请日：2010-11-03
申请人： Jouko Pitkämäki , Robert Sandblom
发明人： Jouko Pitkämäki , Robert Sandblom
CPC分类号： B04B11/082 , B04B1/08 , B04B7/12
摘要： A hermetic centrifugal separator includes a centrifuge rotor, which is arranged to rotate around a center axis and includes a casing which defines an inner separation space, a set of separation discs in the inner separation space, two or more channels which connect to the separation space and include one or more inlet channels for supply of a liquid mixture of components to be separated to the separation space and one or more outlet channels for discharge of a component. The separator includes a torque transmitting part around the center axis and fixedly connected to the centrifuge rotor and an outlet seal between the outlet channel and the rotating centrifuge rotor preventing entrainment of unwanted substances. The separator includes a pump arranged to provide pressure to feed the separated liquid through the outlet channel.
摘要翻译： 密闭式离心分离机包括离心机转子，该离心机转子围绕中心轴线旋转并且包括限定内部分隔空间的壳体，内部分离空间中的一组分离盘，连接到分离空间的两个或更多个通道 并且包括用于供应待分离的部件的液体混合物到分离空间的一个或多个入口通道和用于排出部件的一个或多个出口通道。 分离器包括围绕中心轴线并且固定地连接到离心机转子的扭矩传递部分，以及在出口通道和旋转离心机转子之间的出口密封件，防止夹带不想要的物质。 分离器包括布置成提供压力以通过出口通道供应分离的液体的泵。
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公开(公告)号：US20160121343A1
公开(公告)日：2016-05-05
申请号：US14927726
申请日：2015-10-30
摘要： In one embodiment, a discharger for a centrifuge includes a discharger subassembly including multiple wear plates, each wear plate has an internal surface and an external surface, a receptacle that has lateral dimensions set by the internal surfaces of the multiple wear plates, multiple backing plates laterally positioned around the external surfaces of the multiple wear plates, and at least one spacing mechanism passing through part if the discharger subassembly near the external surface of the multiple wear plates, the discharger also includes a discharger ram to be placed into a receiving area of the discharger subassembly, so on insertion, the wear plates are situated between the discharge ram and the backing plates, and the discharger also includes a discharger shoe assembly joined to the discharger subassembly by the discharger ram, the discharger ram being able to position the discharger shoe assembly.
摘要翻译： 在一个实施例中，用于离心机的排放器包括排放器子组件，其包括多个耐磨板，每个耐磨板具有内表面和外表面，具有由多个耐磨板的内表面设置的侧向尺寸的多个支承板 横向定位在多个耐磨板的外表面周围;以及至少一个间隔机构，如果排放器子组件靠近多个耐磨板的外表面，则排出器还包括排放器柱塞，以将其放置在接收区域 放电器子组件插入时，耐磨板位于排出柱塞和背板之间，并且排放器还包括通过排放器柱塞连接到排放器子组件的排放器鞋组件，排放器柱塞能够将排放器 鞋组装。
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10.发明授权公开(公告)号：US09192945B2
公开(公告)日：2015-11-24
申请号：US13812719
申请日：2011-07-26
CPC分类号： B04B11/02 , A23L2/70 , B04B11/082 , C12H1/061 , C12H1/14
摘要： A separator includes a rotatable drum having a vertical rotational axis, a disk stack arranged in the drum, an inner gripper and an outer gripper that do not rotate with the drum are configured to discharge mutually-separated liquid phases. A discharge line is assigned to each gripper and is arranged in an associated gripper chamber of the drum. The inner gripper includes an inner gripper shaft and the outer gripper includes an outer gripper shaft both of which shafts protrude axially from the drum. Each associated gripper chamber, with its associated gripper, revolves on different radii with respect to the rotational axis such that a chamber is formed radially between an outer circumference of the inner gripper shaft and an inner circumference of the outer gripper shaft. A fluid is insertable into the chamber through a channel, which fluid is pressable from the chamber into the gripper chambers.
摘要翻译： 分离器包括具有垂直旋转轴的可旋转滚筒，布置在滚筒中的盘叠，不与滚筒一起旋转的内夹具和外夹具构造成排出相互分离的液相。 排放管线被分配给每个夹具并且布置在滚筒的相关联的夹持室中。 内部夹持器包括内部夹持器轴，外部夹持器包括外部夹持器轴，两个轴都从滚筒轴向突出。 每个相关联的夹持器腔室及其相关联的夹持器相对于旋转轴线在不同的半径上旋转，使得腔室径向地形成在内部夹持器轴的外周和外部夹持器轴的内周之间。 流体可以通过通道插入腔室中，该通道可从腔室压入夹持器腔室。
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