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公开(公告)号:WO2010126433A1
公开(公告)日:2010-11-04
申请号:PCT/SE2010/050454
申请日:2010-04-23
Applicant: GE HEALTHCARE BIO-SCIENCES AB , LUNDKVIST, Mats
Inventor: LUNDKVIST, Mats
CPC classification number: B01L9/50 , F16B2/243 , F16B2/245 , F16B21/09 , G01N30/6047
Abstract: An attachment arrangement comprising -two resilient arms (1a, 1b) connected to a device to be attached, the other ends of the resilient arms (1a, 1b) pointing away from each other; -one locking part (7a, 7b) on each resilient arm (1a, 1b), said locking parts (7a, 7b) being T- shaped and adapted to together fit into a T-groove by forcing the resilient arms (1a, 1b) towards each other and twist the attachment arrangement during insertion into the T-groove. Said attachment arrangement is secured in the T-groove when the attachment arrangement is twisted back again and the pressure on the resilient arms (1a, 1b) is released. A column holder provided with an attachment arrangement according to the invention.
Abstract translation: 一种连接装置,包括: - 连接到待连接装置的两个弹性臂(1a,1b),弹性臂(1a,1b)的另一端彼此指向; (1a,1b)上的一个锁定部分(7a,7b),所述锁定部分(7a,7b)是T形并且一体地通过迫使弹性臂(1a,1b)配合到T形槽中 )朝向彼此并且在插入T形槽期间扭转附接装置。 当附接装置再次扭转并且弹性臂(1a,1b)上的压力被释放时,所述附接装置固定在T形槽中。 一种柱保持器,其具有根据本发明的附接装置。
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公开(公告)号:WO2013014193A1
公开(公告)日:2013-01-31
申请号:PCT/EP2012/064610
申请日:2012-07-25
Applicant: GE HEALTHCARE BIO-SCIENCES AB , LUNDKVIST, Mats
Inventor: LUNDKVIST, Mats
CPC classification number: G01N1/28 , B01L3/0217 , B01L3/502715 , B01L3/52 , B01L2300/123 , B01L2400/0478 , B01L2400/0487 , B01L2400/065 , G01N35/1097
Abstract: Disclosed is a fluid sample holder 20 for delivering or receiving a fluid sample to or from fluid processing equipment such as a chromatography column 5 (Figure 1). The sample holder 20 comprises: a sample fluid reservoir 15; a sample fluid port 23; a buffer fluid port 21; and a sliding seal 25 within the reservoir 15 having an external area 258 (Figure 3) which generally sealing engages with a wall of the reservoir 15 thereby defining first 22 and second 24 fluid separated regions in the reservoir 15. The sliding seal 25 is displaceable within the reservoir 15 by means of a working fluid pressure differential between the first 22 and second 24 regions to thereby change the respective volumes of the first and second regions, and the external area at least is formed from a plastics moulded material which elastically flexes when subjected to a pressure differential greater than the working fluid pressure differential and when so flexed allows fluid flow between the first and second regions.
Abstract translation: 公开了一种流体样品保持器20,用于将流体样品递送或接收到流体处理设备例如色谱柱5(图1)。 样品保持器20包括:样品流体储存器15; 样品流体端口23; 缓冲液口21; 和储存器15内的滑动密封件25具有外部区域258(图3),该外部区域通常密封地与贮存器15的壁接合,由此限定储存器15中的第一22和第二24个流体分离区域。滑动密封件25可移位 在储存器15内通过第一和第二区域24之间的工作流体压力差,从而改变第一和第二区域的相应体积,并且外部区域至少由塑料模制材料形成,该塑料模制材料弹性弯曲时 受到大于工作流体压力差的压差,并且当其弯曲时允许流体在第一和第二区域之间流动。
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公开(公告)号:WO2010144037A1
公开(公告)日:2010-12-16
申请号:PCT/SE2010/050624
申请日:2010-06-04
Applicant: GE HEALTHCARE BIO-SCIENCES AB , BLOMBERG, Johan , LUNDKVIST, Mats
Inventor: BLOMBERG, Johan , LUNDKVIST, Mats
CPC classification number: G01N35/1097 , B01D15/08 , B01D15/10 , B01D17/12 , B01D29/60 , B01D2201/54 , G01N30/24 , G01N30/38 , G01N30/88 , G01N2030/027 , G01N2030/8804 , G01N2030/8881 , G01N2035/00326 , Y10T137/6416 , Y10T137/6525 , Y10T137/6851 , Y10T137/85986 , Y10T137/87885
Abstract: Automated fluid handling system comprising a housing (20) and two or more fluid handling units (26) arranged as interchangeable modular components with an external fluidics section (30) and an internal non fluidics section (32), and wherein the housing (20) comprises a liquid handling panel (22) with two or more of component positions for receiving said interchangeable modular components (26) such that the external fluidics section (30) is separated from the non fluidics section (32) by the liquid handling panel (22).
Abstract translation: 自动流体处理系统包括壳体(20)和布置成具有外部流体部分(30)和内部非流体部分(32)的可互换模块化部件的两个或更多个流体处理单元(26),并且其中壳体(20) 包括具有用于接收所述可互换模块化部件(26)的两个或更多个部件位置的液体处理板(22),使得外部流体部分(30)通过液体处理板(22)与非流体部分(32)分离 )。
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公开(公告)号:WO2013014195A1
公开(公告)日:2013-01-31
申请号:PCT/EP2012/064612
申请日:2012-07-25
Applicant: GE HEALTHCARE BIO-SCIENCES AB , LUNDKVIST, Mats
Inventor: LUNDKVIST, Mats
CPC classification number: G01N30/16 , B01L3/0217 , B01L3/52 , B01L3/565 , B01L3/567 , B01L2300/123 , B01L2400/0478 , B01L2400/0487 , B01L2400/065 , G01N1/28 , G01N30/04 , G01N30/18 , G01N2030/204
Abstract: Disclosed is a fluid sample holder 20 for delivering or receiving a fluid sample to or from fluid processing equipment such as a chromatography column 5 (Figure 1). The sample holder 20 comprises a sliding seal 25 within a reservoir.The sliding seal 25 is displaceable within the reservoir 15 by means of a fluid pressure differential and includes a valve 260 operable when the sliding seal reaches or substantially reaches an end of its displacement, said valve including a stem 251 having a tapered portion 259 for cooperating with a tapering aperture 262 having a complementary taper, for substantially preventing fluid flow when so cooperating, said stem 251 being displaceable away from said aperture 262 and out of said cooperation at said end of its displacement, to open the valve 260.
Abstract translation: 公开了一种流体样品保持器20,用于将流体样品递送或接收到流体处理设备例如色谱柱5(图1)。 样品保持器20包括在储存器内的滑动密封件25.滑动密封件25可以通过流体压力差在储存器15内移动,并且包括当滑动密封件达到或基本上到达其位移的端部时可操作的阀260, 所述阀包括具有锥形部分259的杆251,所述锥形部分259用于与具有互补锥形的锥形孔262配合,用于当如此配合时基本上防止流体流动,所述杆251可移位远离所述孔262并在所述端部脱离所述协作 的位移,以打开阀门260。
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公开(公告)号:WO2012072494A1
公开(公告)日:2012-06-07
申请号:PCT/EP2011/070953
申请日:2011-11-24
Applicant: GE HEALTHCARE BIO-SCIENCES AB , SALVEN, Owe , OLOVSSON, Bjorn , LUNDKVIST, Mats , KRANSE, Jan
Inventor: SALVEN, Owe , OLOVSSON, Bjorn , LUNDKVIST, Mats , KRANSE, Jan
CPC classification number: F04B53/16 , F04B11/0033 , F04B53/06
Abstract: The invention relates to a chromatography pump, comprising a cylinder (202, 402) in which a piston (204, 404) is arranged for a reciprocating movement; a front element (208) provided with a cylinder head area (210) which together with the cylinder (202, 402) and the piston (204, 404) defines a cylinder space (212); an inlet valve (214) and an outlet valve (216) arranged in the front element (208); an inlet channel (218) arranged in the front element (208) between the inlet valve (214) and the cylinder head area (210); an outlet channel (220) arranged in the front element (208) between the cylinder head area (210) and the outlet valve (216). The inlet channel (218) and outlet channel (220) extend in a substantially straight direction, so that air bubbles (234) are prevented from being trapped within the inlet and outlet channels (218, 220).
Abstract translation: 本发明涉及一种色谱泵,其包括其中布置有用于往复运动的活塞(204,404)的气缸(202,402) 设置有与气缸(202,402)和活塞(204,404)一起限定气缸空间(212)的气缸盖区域(210)的前部元件(208); 布置在前元件(208)中的入口阀(214)和出口阀(216); 布置在入口阀(214)和气缸盖区域(210)之间的前部元件(208)中的入口通道(218); 布置在气缸盖区域(210)和出口阀(216)之间的前部元件(208)中的出口通道(220)。 入口通道(218)和出口通道(220)在基本直的方向上延伸,从而防止气泡(234)被捕获在入口和出口通道(218,220)内。
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公开(公告)号:WO2010138061A1
公开(公告)日:2010-12-02
申请号:PCT/SE2010/050559
申请日:2010-05-24
Applicant: GE HEALTHCARE BIO-SCIENCES AB , GEBAUER, Klaus , KRANSE, Jan , LUNDKVIST, Mats
Inventor: GEBAUER, Klaus , KRANSE, Jan , LUNDKVIST, Mats
CPC classification number: G01N30/6017 , B33Y30/00 , B33Y80/00 , Y10T29/494 , Y10T137/87265
Abstract: A fluid distributor unit comprising a channel system where one or more inlet channels (2) starting on an inlet side (3) of the distributor unit branch out successively into several channels (6) ending on the other side of the distributor unit, called the outlet side (4), characterised in that said distributor unit is provided in one single body (1) by free form fabrication.
Abstract translation: 流体分配器单元,其包括通道系统,其中从分配器单元的入口侧(3)开始的一个或多个入口通道(2)连续分支到在分配器单元的另一侧终止的多个通道(6),称为 出口侧(4),其特征在于,所述分配器单元通过自由形式制造设置在一个单体(1)中。
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公开(公告)号:WO2019229201A1
公开(公告)日:2019-12-05
申请号:PCT/EP2019/064119
申请日:2019-05-29
Applicant: GE HEALTHCARE BIO-SCIENCES AB
Inventor: EHRING, Hanno , LUNDKVIST, Mats , BERGMAN, David , MARCSTRÖM, Andreas
Abstract: Disclosed is an optical flow cell (300') comprising: a housing (910) forming;an enclosed and elongated fluid channel (920) arranged along a first axis (923);a first light guide (961) and a second light guide (962) generally concentrically arranged along a second axis (970) and on opposite side walls of the fluid channel, said first and second light guides having ends (961c,962c) removed in situ to provide a sensing gap (d).
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公开(公告)号:WO2018087339A1
公开(公告)日:2018-05-17
申请号:PCT/EP2017/078965
申请日:2017-11-10
Applicant: GE HEALTHCARE BIO-SCIENCES AB
Inventor: LUNDKVIST, Mats , SALOMONSSON, Daniel
Abstract: Disclosed is a chromatography column cylinder (200) formed from a polymer composite comprising an outer layer (220) and inner layer (210) intended to be in direct contact with the intended contents of the cylinder in a volume (202), wherein the outer layer supports the inner layer, for example when there is negative pressure in the volume (202). In one embodiment, one of said layers is molded directly onto a surface of the other layer such that there is no gap between the two layers. Disclosed also is a method for forming a chromatography column cylinder.
Abstract translation: 公开了一种由聚合物复合材料形成的色谱柱圆柱体(200),所述聚合物复合材料包括外层(220)和内层(210),所述外层(220)和内层(210)旨在直接接触圆柱体的预期内容物 体积(202),其中例如当体积(202)中存在负压时,外层支撑内层。 在一个实施例中,所述层之一被直接模制到另一层的表面上,使得两层之间不存在间隙。 还公开了一种形成色谱柱筒的方法。 p>
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公开(公告)号:WO2017129802A1
公开(公告)日:2017-08-03
申请号:PCT/EP2017/051867
申请日:2017-01-27
Applicant: GE HEALTHCARE BIO-SCIENCES AB
Inventor: DARGY, Stefan , BJERNULF, Olle , LUNDKVIST, Mats
CPC classification number: G01N30/80 , G01N35/1011
Abstract: Disclosed is a fraction collector for dispensing liquids into plural receptacles (P1,P2) arranged in a two dimensional array. The fraction collector comprises a table (22) for supporting said receptacles, and an arm supported above the table, in turn supporting a liquid dispenser (35), the fraction collector arm is rotatable about an arm axis (C) and the liquid dispenser is movable along the arm on a carriage 34 (Figure 2). Thereby, the dispenser is low cost and is repositionable simply above the receptacles as a result of said rotation and as a result of said movement along the arm, without occupying too much laboratory bench space.
Abstract translation: 公开了一种用于将液体分配成布置成二维阵列的多个容器(P1,P2)的分部收集器。 所述馏分收集器包括用于支撑所述接收器的桌子(22)和支撑在所述桌子上方的臂,所述臂又支撑液体分配器(35),所述馏分收集器臂可绕臂轴线(C)旋转,并且所述液体分配器 可沿支架34上的臂移动(图2)。 因此,分配器成本低,并且由于所述旋转和作为所述沿着臂的运动的结果,可简单地重新定位在容器上方,而不会占用太多的实验室工作台空间。 p>
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公开(公告)号:WO2020115165A2
公开(公告)日:2020-06-11
申请号:PCT/EP2019/083735
申请日:2019-12-04
Applicant: GE HEALTHCARE BIO-SCIENCES AB
Inventor: SALOMONSSON, Daniel , LUNDKVIST, Mats
Abstract: Disclosed is a chromatographic separation column assembly (100) comprising a column cylinder (120) having a cylinder wall (126) including an inner wall surface (124) partially defining a column volume (50), and a column component (110/130) insertable into to the cylinder (120), wherein at least an edge region (113/133) of the column component is intended to be in contact or adjacent a part of the inner wall surface (124) in use, the edge region and the contacting or adjacent part of inner wall surface each being formed from a compatible heat fusible material or materials, and wherein at least the cylinder wall in the area of the contacting or adjacent part of the inner wall is formed from a material which allows transmission of the light energy needed to cause said fusing of the adapter plate edge region to the inner wall surface.
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