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    INSTRUMENTS AND METHODS FOR IMPLANTING NUCLEUS REPLACEMENT MATERIAL IN AN INTERVERTEBRAL DISC NUCLEUS SPACE
    91.
    发明申请
    INSTRUMENTS AND METHODS FOR IMPLANTING NUCLEUS REPLACEMENT MATERIAL IN AN INTERVERTEBRAL DISC NUCLEUS SPACE 审中-公开
    用于在椎间盘间隙内插入核素替代材料的仪器和方法

    公开(公告)号：WO2007090030A2

    公开(公告)日：2007-08-09

    申请号：PCT/US2007/061050

    申请日：2007-01-25

    Applicant: WARSAW ORTHOPEDIC, INC. ,  ALLARD, Randall, N. ,  FRANCIS, Tom, J. ,  TRIEU, Hai, H.

    Inventor： ALLARD, Randall, N. ,  FRANCIS, Tom, J. ,  TRIEU, Hai, H.

    CPC classification number: A61F2/4611 ,  A61F2002/444 ,  A61F2002/4627

    Abstract: Instruments and methods are provided for implanting nucleus replacement material in an intervertebral disc nucleus space employing an inserter having proximal and distal end regions and a passageway effective for passing the material therethrough. The distal end region of the inserter includes a conical-shaped outer surface, and the passageway exits through a side surface of the inserter in the distal end region at other than the apex of the conical-shaped outer surface. The nucleus replacement material passing through the inserter exits into an intervertebral disc nucleus space when the passageway exit in the side surface at the distal end region is disposed in the nucleus space. The instrument may also include a cover locking mechanism having pivotally connected first and second cover plates with a latching tab and landing sized and configured to mate and lock the cover plates automatically when the inserter assumes an implanting configuration.

    Abstract translation: 提供的仪器和方法用于使用具有近端和远端区域的插入器以及有效地使材料通过其中的通道将细胞核置换材料植入椎间盘细胞核空间中。 插入器的远端区域包括圆锥形的外表面，并且该通道在除圆锥形外表面的顶点之外的远端区域中通过插入器的侧表面离开。 通过插入器的核置换材料在远端区域的侧表面中的通道出口设置在细胞核空间中时，离开椎间盘细胞核空间。 仪器还可以包括具有枢转连接的第一和第二盖板的盖锁定机构，其具有锁定突片和着陆部，其尺寸和构造在插入器呈现植入构造时自动地配合和锁定盖板。

    SURFACE TREATMENTS FOR PROMOTING SELECTIVE TISSUE ATTACHMENT TO MEDICAL IMPLANTS
    92.
    发明申请
    SURFACE TREATMENTS FOR PROMOTING SELECTIVE TISSUE ATTACHMENT TO MEDICAL IMPLANTS 审中-公开
    促进选择性组织与医用植入物接触的表面处理

    公开(公告)号：WO2006116374A3

    公开(公告)日：2007-08-02

    申请号：PCT/US2006015583

    申请日：2006-04-24

    Applicant: WARSAW ORTHOPEDIC INC ,  TRIEU HAI H ,  MOLZ FRED

    Inventor： TRIEU HAI H ,  MOLZ FRED

    IPC: A61L27/54 ,  A61L31/16

    CPC classification number: A61L27/50 ,  A61F2/30767 ,  A61F2002/30028 ,  A61F2002/3093 ,  A61F2002/30932 ,  A61F2250/0051 ,  A61L27/54 ,  A61L31/16 ,  A61L2300/414 ,  A61L2400/18

    Abstract: Embodiments include a method for promoting selective tissue attachment to medical implants. By treating implant surfaces where tissue attachment is desired with tissue attachment promoting treatments, and treating implant surfaces where tissue attachment is not desired with tissue attachment inhibiting treatments, selective tissue attachment to medical implants may be achieved. Also, embodiments include an implant with at least one tissue contacting surface and at least one secondary surface where tissue attachment is not desired, and appropriate tissue attachment promoting or inhibiting treatments on the surfaces.

    Abstract translation: 实施例包括用于促进对医疗植入物的选择性组织附着的方法。 通过处理植入物表面，其中组织附着需要组织附着促进治疗，并且通过组织附着抑制治疗来治疗不需要组织附着的植入物表面，可以实现对医疗植入物的选择性组织附着。 此外，实施方案包括具有至少一个组织接触表面和至少一个辅助表面的植入物，其中不需要组织附着，以及在表面上促进或抑制治疗的适当的组织附着。

    METHODS AND DEVICES FOR THE TREATMENT OF INTERVERTEBRAL DISCS
    100.
    发明申请
    METHODS AND DEVICES FOR THE TREATMENT OF INTERVERTEBRAL DISCS 审中-公开
    用于治疗椎间盘突出症的方法和装置

    公开(公告)号：WO2005014071A1

    公开(公告)日：2005-02-17

    申请号：PCT/US2004/025389

    申请日：2004-08-06

    Applicant: SDGI HOLDINGS, INC. ,  TRIEU, Hai, H.

    Inventor： TRIEU, Hai, H.

    IPC: A61L27/00

    CPC classification number: A61K47/32 ,  A61F2002/30586 ,  A61F2002/30677 ,  A61F2002/444 ,  A61K9/0024 ,  A61K47/34 ,  A61L27/54 ,  A61L2300/254 ,  A61L2300/414 ,  A61L2300/45 ,  A61L2300/602 ,  A61L2300/622 ,  A61L2430/38

    Abstract: Devices for the treatment of intervertebral discs are described. The devices, when implanted into the nucleus pulposus of an intervertebral disc, provide for the controlled release of one or more active agents into the disc. The active agent can be a chemonucleolytic agent such as chymopapain. The device can also comprise one or more binders. The device can be an elongate solid body having a tapered or rounded insertion end. Alternatively, the device can include a plurality of particles. For devices containing multiple active agents, the configuration of the device be chosen to provide for the sequential or simultaneous release of each of the active agents. The elongate solid body can include a sheath comprising a first active agent and a core comprising a second active agent. Methods of making the devices and methods of treatment comprising implanting the devices into an intervertebral disc are also described.

    Abstract translation: 描述了用于治疗椎间盘的装置。 当植入到椎间盘的髓核中时，这些装置提供了将一种或多种活性剂受控释放到椎间盘中。 活性剂可以是化学溶解剂如木瓜凝乳蛋白酶。 该装置还可以包括一种或多种粘合剂。 该装置可以是具有锥形或圆形插入端的细长实心体。 或者，该装置可以包括多个颗粒。 对于包含多个活性剂的装置，选择装置的配置来提供每个活性剂的顺序或同时释放。 细长固体可以包括包含第一活性剂和包含第二活性剂的核心的护套。 还描述了制造装置的方法和包括将装置植入椎间盘的治疗方法。

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