公开(公告)号：WO2018081253A1

公开(公告)日：2018-05-03

申请号：PCT/US2017/058266

申请日：2017-10-25

Applicant: SMITH, Michael, D.

Inventor： SMITH, Michael, D.

IPC: A61B10/00

Abstract: A handheld surgical device with a working portion driven by a motor, wherein the working portion is contained in a concave-shaped portion when it is not activated, and the working portion becomes exposed from the concave-shaped portion when it is activated. The activation of the working portion can be controlled by a switch located at a handle portion of the handheld surgical device. The handheld surgical device includes a concave-shaped portion with a cutting edge, which is not driven by the motor.

Abstract translation: 手持式外科手术装置，其具有由马达驱动的工作部分，其中，当工作部分未被激活时，该工作部分被容纳在凹形部分中，并且工作部分从凹形形状 当它被激活时。 工作部分的激活可以通过位于手持式手术装置的手柄部分处的开关来控制。 手持式手术装置包括具有切割边缘的凹形部分，该切割边缘不由马达驱动。

公开(公告)号：WO2012127221A2

公开(公告)日：2012-09-27

申请号：PCT/GB2012/050607

申请日：2012-03-20

Applicant: PERKINS ENGINES COMPANY LIMITED ,  ANANTHASIVAN, Venkatramanan V ,  BABBE, Alexander ,  CRAWFORD, Christopher ,  SMITH, Michael D

Inventor： ANANTHASIVAN, Venkatramanan V ,  BABBE, Alexander ,  CRAWFORD, Christopher ,  SMITH, Michael D

IPC: F02D31/00 ,  F16H61/16 ,  B60W10/06

CPC classification number: B60W10/06 ,  B60W10/10 ,  B60W10/11 ,  B60W30/146 ,  B60W2050/0024 ,  B60W2510/0604 ,  B60W2510/0638 ,  B60W2710/0644 ,  B60W2710/0661 ,  B60W2710/1005 ,  F02D31/006 ,  F02D31/009 ,  F16H61/16 ,  F16H2061/166

Abstract: An engine forming part of a machine is controlled in order to effect a predetermined machine speed limit. One or more engine control parameters are determined based on a theoretical engine speed limit that is based on the predetermined machine speed limit and variable machine parameters. This comprises one or more of: varying a control software engine speed limit from a first engine speed value to a desired engine speed limit value that is based on the theoretical limit; setting the control software engine speed limit at a locked engine speed limit value that remains constant when the theoretical limit is within a set range; setting an engine governor gain based on the theoretical limit; setting control software engine speed filter parameters based on the theoretical limit; and determining control commands to prevent the machine transmission from changing gears based on the engine speed limit with a hysteresis applied.

Abstract translation: 控制机器的一部分的发动机，以实现预定的机器速度限制。 基于基于预定机器速度限制和可变机器参数的理论发动机速度限制来确定一个或多个发动机控制参数。 这包括以下中的一个或多个：将控制软件引擎速度限制从第一发动机速度值改变到基于理论极限的期望的发动机速度极限值; 在理论极限在设定范围内时，在锁定的发动机速度限制值下设定控制软件引擎速度限制，该值保持恒定; 根据理论限制设定引擎调速器增益; 基于理论限制设置控制软件引擎速度滤波器参数; 并确定控制命令以防止机器传输根据发动机速度限制而变化，并施加滞后。

公开(公告)号：WO2009100028A1

公开(公告)日：2009-08-13

申请号：PCT/US2009/032880

申请日：2009-02-02

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ,  TSENG, Hsian-rong ,  KAMEI, Kenichiro ,  SUN, Jing ,  MISCHEL, Paul S. ,  MASTERMAN-SMITH, Michael D. ,  NATHANSON, David A. ,  HUANG, Tiffany ,  VAN DAM, Michael ,  BEHRENBRUCH, Christian ,  SARKARIA, Shawn M.

Inventor： TSENG, Hsian-rong ,  KAMEI, Kenichiro ,  SUN, Jing ,  MISCHEL, Paul S. ,  MASTERMAN-SMITH, Michael D. ,  NATHANSON, David A. ,  HUANG, Tiffany ,  VAN DAM, Michael ,  BEHRENBRUCH, Christian ,  SARKARIA, Shawn M.

IPC: C12M3/00 ,  G01N1/30

CPC classification number: C12M23/16 ,  B01L3/021 ,  B01L3/502715 ,  B01L2200/027 ,  B01L2300/0816 ,  G01N15/1484 ,  G01N35/1065 ,  G01N2015/1006 ,  G01N2015/1477 ,  G01N2035/00158 ,  G01N2035/1039

Abstract: A microfluidic system has a pipette system comprising a plurality of pipettes, a microfluidic chip arranged proximate the pipette system, an imaging optical detection system arranged proximate the microfluidic chip, and an image processing system in communication with the imaging optical detection system. The microfluidic chip has a plurality of cell culture chambers defined by a body of the microfluidic chip, each cell culture chamber being in fluid connection with an input channel and an output channel defined by the microfluidic chip. The pipette system is constructed and arranged to at least one of inject fluid through the plurality of pipettes into the plurality of input channels or extract fluid through the plurality of pipettes from the plurality of output channels while the microfluidic system is in operation.

Abstract translation: 微流体系统具有包括多个移液管的移液管系统，靠近移液管系统布置的微流体芯片，布置在微流体芯片附近的成像光学检测系统以及与成像光学检测系统通信的图像处理系统。 微流体芯片具有由微流体芯片的主体限定的多个细胞培养室，每个细胞培养室与输入通道和由微流体芯片限定的输出通道流体连接。 移液管系统被构造并布置成通过多个移液管的注射流体中的至少一个进入多个输入通道，或者在微流体系统运行时从多个输出通道提取流体通过多个移液管。

公开(公告)号：WO1997026847A1

公开(公告)日：1997-07-31

申请号：PCT/US1997000457

申请日：1997-01-17

Applicant: ADVANCED BIO SURFACES, INC. ,  FELT, Jeffrey, C. ,  BOURGEAULT, Craig, A. ,  BAKER, Matthew, W. ,  RYDELL, Mark, A. ,  SMITH, Michael, D.

Inventor： ADVANCED BIO SURFACES, INC.

IPC: A61F02/44

CPC classification number: A61B17/7098 ,  A61B1/00165 ,  A61B17/00234 ,  A61B17/1671 ,  A61B17/1682 ,  A61B17/1684 ,  A61B17/1686 ,  A61B17/1757 ,  A61B17/7097 ,  A61B17/8855 ,  A61B2017/00535 ,  A61F2/28 ,  A61F2/30756 ,  A61F2/30767 ,  A61F2/3099 ,  A61F2/32 ,  A61F2/38 ,  A61F2/4081 ,  A61F2/4202 ,  A61F2/441 ,  A61F2/442 ,  A61F2/4601 ,  A61F2/4611 ,  A61F2002/30024 ,  A61F2002/30583 ,  A61F2002/30957 ,  A61F2002/4233 ,  A61F2002/444 ,  A61F2002/4635 ,  A61F2210/0085 ,  A61F2250/0021 ,  A61L27/18 ,  A61L29/041 ,  A61L29/06 ,  A61L2430/38 ,  C08G18/10 ,  C08G18/4854 ,  C08G18/69 ,  Y10S623/92 ,  C08L83/04 ,  C08L75/04 ,  C08L23/00 ,  C08L67/02 ,  C08G18/3206

Abstract: A method and related materials and apparatus for using minimally invasive means to repair (e.g., reconstruct) tissue such as fibrocartilage, and particularly fibrocartilage associated with diarthroidal and amphiarthroidal joints. The method involves the use of minimally invasive means to access and prepare damaged or diseased fribrocartilage within the body, and to then deliver a curable biomaterial, such as a curable polyurethane system, to the prepared site, and to cure the biomaterial in situ in order to repair the fibrocartilage. Applications include repair (e.g., reconstruction or replacement) of the intervertebral disc of the spine. An apparatus is provided in the form of an uninflated balloon that can be inserted into the disc space and there inflated with biomaterial in order to distract the space and provide a permanent replacement disc.

Abstract translation: 一种使用微创手段来修复（例如，重建）诸如纤维软骨的组织，特别是与二骨关节和关节软骨关节相关联的纤维软骨的方法和相关材料和装置。 该方法涉及使用微创手段来获取和准备身体内的受损或患病的飞行物质，然后将可固化生物材料（例如可固化的聚氨酯体系）递送到制备的部位，并按顺序固化原位生物材料 修复纤维软骨。 应用包括脊椎椎间盘的修复（例如，重建或替换）。 提供了一种未充气气囊的形式的装置，其可以插入椎间盘空间中，并且用生物材料膨胀，以便分散空间并提供永久替换盘。

公开(公告)号：WO2017120467A1

公开(公告)日：2017-07-13

申请号：PCT/US2017/012529

申请日：2017-01-06

Applicant: SMITH, Michael, D.

Inventor： SMITH, Michael, D.

IPC: A61B17/3205

CPC classification number: A61B17/1633 ,  A61B17/1615 ,  A61B17/1622 ,  A61B17/32002 ,  A61B17/320708 ,  A61B2017/00353 ,  A61B2017/00367 ,  A61B2017/00991 ,  A61B2017/320052 ,  A61B2090/08021

Abstract: A handheld surgical device having a working portion that can be covered or uncovered. The working portion of the handheld surgical device can have an advanced position or a retracted position, which can be controlled by one or more switch(s) at the handle portion of the handheld surgical device. The handheld surgical device can also include a shroud that can cover the working portion having a cutting blade driven by a powered motor. The shroud can also have a cutting edge, which is not driven by the powered motor.

Abstract translation: 手持式手术装置具有可被覆盖或未被覆盖的工作部分。 手持式手术装置的工作部分可以具有前进位置或缩回位置，其可以通过手持式手术装置的手柄部分处的一个或多个开关来控制。 手持式手术装置还可以包括护罩，该护罩可以覆盖具有由动力马达驱动的切割刀片的工作部分。 护罩还可以有一个切割边缘，不受电动马达驱动。

公开(公告)号：WO2010011708A2

公开(公告)日：2010-01-28

申请号：PCT/US2009/051344

申请日：2009-07-22

Applicant: WELCH ALLYN, INC. ,  LANE, John, A. ,  KUGLER, Andrew ,  FAHRENKRUG, Corinn ,  GUNTER, Suzanne, Abate ,  KRAUTER, Allan ,  MCCANN, Lucas, C. ,  TUDOR, Ashley, E. ,  SMITH, Michael, D. ,  SCOTT, William

Inventor： LANE, John, A. ,  KUGLER, Andrew ,  FAHRENKRUG, Corinn ,  GUNTER, Suzanne, Abate ,  KRAUTER, Allan ,  MCCANN, Lucas, C. ,  TUDOR, Ashley, E. ,  SMITH, Michael, D. ,  SCOTT, William

IPC: A61M37/00 ,  A61M5/00

CPC classification number: A61B5/0059 ,  A61B5/411 ,  A61B5/441 ,  A61B5/6833

Abstract: A flexible and disposable allergen-containing patch is provided with markings transferable to the skin. The patch may also include piercing elements to become an all-in-one system. A reusable actuator enables a user with little training or experience to administer multiple test injections with the disposable patch. A scope allows magnified viewing of a test site after the skin test is provided, the scope incorporating the patch as a releasable component. An all-in-one applicator assembly that can be bent to fit a convex engagement surface of a rolling actuator is also provided.

Abstract translation: 一种柔性且一次性的含过敏原的贴剂具有可转移至皮肤的标记。 贴片还可以包括刺穿元件以成为一体化系统。 可重复使用的执行器使用户几乎没有培训或经验，可以使用一次性贴剂进行多次测试注射。 范围允许在提供皮肤测试之后放大观察测试位置，该范围将贴片作为可释放组件。 还提供了可以弯曲以配合滚动致动器的凸形接合表面的一体式涂敷器组件。

公开(公告)号：WO2004109443A3

公开(公告)日：2004-12-16

申请号：PCT/US2004/016848

申请日：2004-05-27

Applicant: LIQUID MACHINES, INC. ,  LESER, Norbert ,  KYNE, Fajen ,  MORGAN, Robert ,  BARCLAY, Christopher, B. ,  GAUDET, Edward, J. ,  SCHOONMAKER, James ,  EPSTEIN, Arnold, S. ,  SMITH, Michael, D.

Inventor： LESER, Norbert ,  KYNE, Fajen ,  MORGAN, Robert ,  BARCLAY, Christopher, B. ,  GAUDET, Edward, J. ,  SCHOONMAKER, James ,  EPSTEIN, Arnold, S. ,  SMITH, Michael, D.

IPC: G06F11/30

Abstract: In a network of intermittently-connected computers (200), a method and apparatus for maintaining and managing control over data objects (32) authored, accessed, and altered by users in dynamic, distributed, and collaborative contexts. The invention method and apparatus attach to each data object an identification (23) of a respective control policy. Each control policy comprises at least an indication of a subset of the users (20) who may access the data object, an indication of the privileges granted to each subset of users able to access the data object, and an indication of a subset or users (30) who may define or edit the control policy. The invention method and apparatus separate the management control policies (27) of data objects from the creation and use of the data objects. The invention method and apparatus automate common policy changes, distribution of policy changes to the enforcement agents, and propagation of control policies to derivative works.