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    METHOD AND KIT FOR DELIVERING REGENERATIVE ENDODONTIC TREATMENT
    11.
    发明申请
    METHOD AND KIT FOR DELIVERING REGENERATIVE ENDODONTIC TREATMENT 审中-公开
    用于输送再生内源性治疗的方法和工具包

    公开(公告)号：WO2009078971A1

    公开(公告)日：2009-06-25

    申请号：PCT/US2008/013699

    申请日：2008-12-12

    Applicant: NOVA SOUTHEASTERN UNIVERSITY ,  MURRAY, Peter E. ,  GARCIA-GODOY, Franklin

    Inventor： MURRAY, Peter E. ,  GARCIA-GODOY, Franklin

    IPC: A61K6/00

    CPC classification number: A61K6/0032

    Abstract: The present invention provides novel methods and kits for removing unhealthy or necrotic pulp tissue from inside the root canals of a tooth, and to replace it with new vascularized tissue created by regenerative endodontic treatment. The present invention provides alternatives to current root canal therapies, as well as obturation of the root canal with dental materials.

    Abstract translation: 本发明提供了用于从牙根的根管内去除不健康或坏死牙髓组织的新方法和试剂盒，并且用再生牙髓治疗产生的新的血管化组织代替它。 本发明提供了当前根管治疗的替代方案，以及牙根材料的根管封堵。

    A METHOD OF TREATMENT OF THE DENTAL PULP AND FILLING ROOT CANALS USING WATER-BASED MATERIALS
    13.
    发明申请
    A METHOD OF TREATMENT OF THE DENTAL PULP AND FILLING ROOT CANALS USING WATER-BASED MATERIALS 审中-公开
    使用水基材料处理牙髓和填充根管的方法

    公开(公告)号：WO2008100451A2

    公开(公告)日：2008-08-21

    申请号：PCT/US2008001758

    申请日：2008-02-08

    Applicant: DENTSPLY INT INC ,  PRIMUS CAROLYN M ,  GUTMANN JAMES L ,  BREUER MIKLOS M ,  JEFFERIES STEVEN R

    Inventor： PRIMUS CAROLYN M ,  GUTMANN JAMES L ,  BREUER MIKLOS M ,  JEFFERIES STEVEN R

    IPC: A61K6/00

    CPC classification number: A61K6/083 ,  A61K6/0032 ,  A61K6/0038 ,  A61K6/0067 ,  A61K6/007 ,  A61K6/0073 ,  A61K6/0088 ,  A61K6/033 ,  A61K6/06 ,  A61K6/0612 ,  A61K6/0637 ,  A61K6/0675 ,  A61K6/0681 ,  A61K6/0835 ,  A61K6/0035 ,  C08L39/06 ,  C08L29/04 ,  C08L31/04 ,  C08L33/08 ,  C08L33/10 ,  C08L33/14

    Abstract: Improved compositions comprising a mixture of particulate materials with water-based liquids containing water-soluble polymers and surfactants are provided. Examples of particulate powders include mixtures of calcium silicate, calcium aluminate, calcium sulfate, and hydroxyapatite. Examples of water-soluble polymers include polyvinyl alcohols, polyvinyl pyrrolidone, partially hydrolyzed polyvinyl acetates, polyacrylic acid, and polymethacrylic acid. Surfactants such as sodium dodecyl sulfate are added to the composition to interact with the polymeric materials. The compositions are particularly suitable for sealing and obturating dental root canals and root apices. The composition provides a stable barrier to bacterial' and fluid leakage in the root canal system of a tooth. In addition, the compositions help promote the growth of new bone and tissue surrounding the root-tip area or dentin tissue that covers an injured or amputated pulp.

    Abstract translation: 提供了包含颗粒材料与含有水溶性聚合物和表面活性剂的水性液体的混合物的改进的组合物。 颗粒粉末的实例包括硅酸钙，铝酸钙，硫酸钙和羟基磷灰石的混合物。 水溶性聚合物的实例包括聚乙烯醇，聚乙烯吡咯烷酮，部分水解的聚乙酸乙烯酯，聚丙烯酸和聚甲基丙烯酸。 将表面活性剂如十二烷基硫酸钠加入到组合物中以与聚合物材料相互作用。 该组合物特别适用于密封和填充牙根管和根尖。 该组合物为牙根管系统中的细菌和流体泄漏提供了稳定的屏障。 此外，该组合物有助于促进覆盖受伤或截肢的纸浆的根尖区域或牙本质组织周围的新骨骼和组织的生长。

    DENTAL OBTURATOR POINT
    14.
    发明申请
    DENTAL OBTURATOR POINT 审中-公开
    牙科点阻塞器

    公开(公告)号：WO2008046557A1

    公开(公告)日：2008-04-24

    申请号：PCT/EP2007/008859

    申请日：2007-10-11

    Applicant: DENTSPLY DE TREY GMBH ,  KLEE, Joachim, E.

    Inventor： KLEE, Joachim, E.

    IPC: A61K6/00 ,  A61K6/087

    CPC classification number: A61K6/0032 ,  A61C5/50 ,  A61K6/024 ,  A61K6/025

    Abstract: Dental obturator point having an obturation body of a material comprising (a) a polymer blend comprising (a1) 5 to 95 wt% based on the total amount of the polymer blend of a thermoplastic epoxide amine addition polymer, and (a2) 95 to 5 wt% based on the total blend of a high performance polymer; and (b) a particulate filler; whereby the obturation body has a radio opacity of at least 3 mm/mm Al.

    Abstract translation: 具有与材料的充填体，包括牙科闭孔点（a）一种聚合物共混物，其包括基于热塑性环氧胺加成聚合物的聚合物共混物的总量（A1）5〜95重量％，和（a2）95〜5 基于高性能聚合物的总混合物上重量％; 和（b）一种微粒填充剂; 由此密闭体具有至少为3毫米/毫米的Al无线电不透明度。

    PHOSPHONATE FOR MECHANICAL DENTAL TREATMENT
    15.
    发明申请
    PHOSPHONATE FOR MECHANICAL DENTAL TREATMENT 审中-公开
    用于机械牙科治疗的磷酸盐

    公开(公告)号：WO2005123007A1

    公开(公告)日：2005-12-29

    申请号：PCT/CH2005/000313

    申请日：2005-06-06

    Applicant: UNIVERSITÄT ZÜRICH ,  ZEHNDER, Matthias ,  SENER, Beatrice

    Inventor： ZEHNDER, Matthias ,  SENER, Beatrice

    IPC: A61K6/00

    CPC classification number: A61K6/0032 ,  A61K6/0029 ,  C08L71/02

    Abstract: The invention relates to the use of a phosphonate for the manufacture of a pharmaceutical preparation for use in a mechanical treatment of dental hard tissues. Moreover, the invention relates to a pharmaceutical preparation for use in a dental treatment that comprises a calcium complexing agent and an oxidizing agent, wherein said calcium complexing agent is a phosphonate.

    Abstract translation: 本发明涉及膦酸盐在制备用于牙科硬组织机械处理的药物制剂中的用途。 此外，本发明涉及一种用于牙科治疗的药物制剂，其包含钙络合剂和氧化剂，其中所述钙络合剂是膦酸酯。

    ADHESIVE ENDODONTIC CONES AND RELATED METHODS
    17.
    发明申请
    ADHESIVE ENDODONTIC CONES AND RELATED METHODS 审中-公开
    粘附性内分泌物及相关方法

    公开(公告)号：WO2004091420A2

    公开(公告)日：2004-10-28

    申请号：PCT/US2004/010524

    申请日：2004-04-07

    Applicant: ULTRADENT PRODUCTS, INC.

    Inventor： HASCHKE, Erich

    IPC: A61C

    CPC classification number: A61K6/0032 ,  A61C5/50 ,  C08L75/16 ,  C08L33/00

    Abstract: An adhesive endodontic cone (10) is chemically compatible with endodontic sealant resins, including hydrophilic resins used for sealing root canal chamber. The adhesive endodontic cone (10) comprises a hydrophobic elastomer substrate that is sized and shaped so as to be at least partially insertable into an exposed root canal of tooth. The cone includes an adhesive (14) attached to at least a portion of a surface of the cone (10) so as to render the cone (10) more chemically compatible with a hydrophilic endodontic resin. The adhesive (14) includes a hydrophobic portion that is chemically compatible with the hydrophobic elastomer substrate and a hydrophilic portion that is chemically compatible with a hydrophilic resin.

    Abstract translation: 粘性牙根管锥（10）与牙髓密封剂树脂化学相容，包括用于密封根管腔的亲水性树脂。 粘性牙根管锥体（10）包括疏水性弹性体基底，其尺寸和形状被至少部分地插入到暴露的牙根管中。 圆锥体包括附着到锥体（10）的表面的至少一部分上的粘合剂（14），以使得锥体（10）与亲水性牙髓固化树脂更具化学相容性。 粘合剂（14）包括与疏水弹性体基材化学相容的疏水部分和与亲水性树脂化学相容的亲水部分。

    USE OF CHLORHEXIDINE IN THE PREVENTION OF ROOT CARIES
    18.
    发明申请
    USE OF CHLORHEXIDINE IN THE PREVENTION OF ROOT CARIES 审中-公开
    氯丙嗪在预防根癌中的应用

    公开(公告)号：WO0174321A3

    公开(公告)日：2002-05-16

    申请号：PCT/IB0100794

    申请日：2001-04-03

    Applicant: CHX TECHNOLOGIES INC ,  SYMINGTON JOHN M ,  SYMINGTON ALISON ,  TEN CATE ARNOLD R ,  PERRY OLIVER R

    Inventor： SYMINGTON JOHN M ,  SYMINGTON ALISON ,  TEN CATE ARNOLD R ,  PERRY OLIVER R

    IPC: A61K6/00 ,  A61K8/43 ,  A61Q11/00 ,  A61K7/16 ,  A61K31/155

    CPC classification number: A61K6/0032 ,  A61K6/0017 ,  A61K8/43 ,  A61Q11/00 ,  C08L75/04

    Abstract: Topical application of a solution of the antimicrobial chlorhexidine to teeth, particularly including exposed root surfaces, prevents the destruction of exposed cementum and associated exposed enamel at the cementum-enamel junction on tooth root surfaces (root caries) and the inflammation of the gingival tissue. In a method of use, a topical solution containing 10% (w/v) chlorhexidine, 20% (w/v) Sumatra benzoin, and 70% (w/v) ethanol is applied to the appropriate area of the tooth surface, followed immediately by application of a sealant which is a solution containing 29% (w/v) medical-grade polyurethane in 49% (w/v) acetone and 22% (w/v) ethyl acetate. Application of the chlorhexidine and sealant to the tooth cementum and gingival margin of "at risk" older adult patients has significantly reduced the prevalence and incidence of root caries and gingival inflammation.

    Abstract translation: 将抗微生物氯己定溶液局部应用于牙齿，特别是包括暴露的根表面，可防止在牙根表面（根龋齿）牙根牙釉质接合处和牙龈组织炎症时暴露的牙骨质和相关暴露牙釉质的破坏。 在使用方法中，将含有10％（w / v）氯己定，20％（w / v）苏门答腊安息香和70％（w / v）乙醇的局部溶液施加到牙齿表面的适当区域，随后 立即通过在49％（w / v）丙酮和22％（w / v）乙酸乙酯中施加含有29％（w / v）医用级聚氨酯的溶液的密封剂。 氯己定和密封剂对牙骨质质和“有风险”的老年成人患者的牙龈边缘的应用显着降低了龋齿和牙龈炎症的发病率和发病率。

    A METHOD FOR IMPROVING PENETRATION OR LONG TERM ADHESION OF COMPOSITIONS TO DENTAL TISSUES AND COMPOSITIONS USABLE IN SAID METHOD
    20.
    发明申请
    A METHOD FOR IMPROVING PENETRATION OR LONG TERM ADHESION OF COMPOSITIONS TO DENTAL TISSUES AND COMPOSITIONS USABLE IN SAID METHOD 审中-公开
    用于改善组合物渗透或长期粘合到牙科组织中的方法和可用于所述方法的组合物

    公开(公告)号：WO2012146832A3

    公开(公告)日：2013-03-14

    申请号：PCT/FI2012050422

    申请日：2012-04-30

    Applicant: OULUN YLIOPISTO ,  TJAEDERHANE LEO

    Inventor： TJAEDERHANE LEO

    IPC: A61K6/00

    CPC classification number: A61K6/027 ,  A61K6/0029 ,  A61K6/0032 ,  A61K6/0047 ,  A61Q11/00 ,  C08L33/00

    Abstract: This invention concerns a method of improving penetration of compositions to dentin, enamel, dental pulp or cement and dental compositions for restoration or decoration of teeth, for use in pulp medication comprising, for root canal disinfection and/or obturation and for desensitizing. This invention also concerns uses of DMSO for improving the bond strength of dental composition and in preparing dental compositions. Further the invention concerns a new method of treating teeth so that penetration of components is increased.

    Abstract translation: 本发明涉及一种改善组合物渗透到牙质，牙釉质，牙髓或水泥的牙科用组合物和用于牙齿修复或装饰的牙科用组合物的方法，所述牙齿组合物用于牙髓药物，包括根管消毒和/或封闭和脱敏。 本发明还涉及DMSO用于改善牙科组合物的粘合强度和制备牙科用组合物的用途。 此外，本发明涉及一种治疗牙齿的新方法，使得组分的渗透增加。

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