公开(公告)号：WO2019210318A1

公开(公告)日：2019-10-31

申请号：PCT/US2019/029722

申请日：2019-04-29

Applicant: MILLENNIUM PHARMACEUTICALS, INC.

Inventor： GALAS, Richard John, Jr.

IPC: B65B3/04 ,  B65B3/12 ,  B65B3/26 ,  B67C3/00 ,  B67C3/12

Abstract: Systems and methods for distributing a filling fluid are discussed. More particularly an exemplary filling system may include a reservoir holding a filling fluid for distribution. The filling system may also include a pump and filling nozzle fluidly coupled to the reservoir. A processor executes a filling module that when executed receives at least one input fluid property of the filling fluid and generates at least one set of operating parameters for controlling operation of the pump during a filling operation based at least in part on the fluid property. The generated set of operating parameters enable control of the pump to distribute the filling fluid through the filling nozzle, such that a fluid interface with a stable resting profile forms in the filling fluid in the filling nozzle adjacent to the nozzle opening after the filling fluid is distributed from the filling nozzle.

公开(公告)号：WO2018144325A1

公开(公告)日：2018-08-09

申请号：PCT/US2018/015367

申请日：2018-01-26

Applicant: NORDSON CORPORATION

Inventor： SPRINGHORN, Robert, W.

IPC: B05C17/005 ,  B05C17/01 ,  B65D81/32 ,  B65B3/12

Abstract: A dual fluid cartridge assembly (30) includes a cartridge (32), a flange (56), and a piston tube (36). The cartridge defines a channel and includes said flange. The flange defines a cavity (78) that extends from a cavity opening (80) to a cavity base (82). The cavity opening is positioned within the channel of the cartridge, and the cavity base is positioned external to the cartridge. The piston tube has an extended end (57), and is positioned at least partially within the channel. The extended end is positioned within the cavity.

公开(公告)号：WO2016127211A1

公开(公告)日：2016-08-18

申请号：PCT/AU2016/050077

申请日：2016-02-10

Applicant: FLUID TRANSFER TECHNOLOGY PTY LTD

Inventor： MCINNES, Luke William ,  BONDI, John Raymond ,  BONDI, Brian Mark

IPC: G01N1/14 ,  B65B3/12

CPC classification number: G01N1/14 ,  G01N1/2035 ,  G01N2001/1427 ,  G01N2001/2071

Abstract: The invention provides a liquid sampler for the automated sampling of liquids at dedicated pre-determined intervals. The liquid sampler includes a liquid inlet connectable to a liquid circuit containing a liquid to be sampled, a sampling reservoir for collecting a liquid sample, and a sampling pump connected to the liquid inlet, operable to extract a discrete amount of liquid from the liquid inlet and to discharge the discrete amount of liquid into the sampling reservoir.

Abstract translation: 本发明提供一种液体采样器，用于以专用的预定间隔自动采样液体。 液体采样器包括可连接到液体回路的液体入口，该液体回路包含待采样的液体，用于收集液体样品的采样容器和连接到液体入口的采样泵，可操作以从液体入口抽取离散量的液体 并将离散量的液体排出到采样储存器中。

公开(公告)号：WO2014077857A1

公开(公告)日：2014-05-22

申请号：PCT/US2012/066336

申请日：2012-11-21

Applicant: REGENERON PHARMACEUTICALS, INC.

Inventor： DISSANAYAKE, Tikiri Jean

IPC: B65B3/00 ,  B65B3/22 ,  B65B3/12

CPC classification number: B65B3/04 ,  B65B3/003 ,  B65B3/06 ,  B65B3/12 ,  B65B3/22

Abstract: A pre-sterilized system (5) for dispensing biopharmaceutical materials includes a reservoir (10) for holding biopharmaceutical materials coupled to a filter and distribution manifold (20) connected to a plurality of receiving containers (30). The manifold (20) includes a plurality of container conduits (60) and a plurality of distribution conduits (50). The plurality of container conduits (60) is connected to the plurality of receiving containers (30) and supports the plurality of distribution conduits (50) above the plurality of receiving containers (30) to allow flow of the biopharmaceutical materials from the plurality of distribution conduits (50) by gravity into the plurality of receiving containers (30. The plurality of receiving containers (30) and the manifold (20) are sealed relative to an ambient environment outside the manifold and the plurality of containers to inhibit contamination of the biopharmaceutical materials when the biopharmaceutical materials are inside at least one of the plurality of receiving containers (30 and the manifold (20).

Abstract translation: 用于分配生物药物材料的预灭菌系统（5）包括用于容纳连接到过滤器的生物药物的储存器（10）和连接到多个接收容器（30）的分配歧管（20）。 歧管（20）包括多个容器管道（60）和多个分配导管（50）。 多个容器管道（60）连接到多个接收容器（30）并且支撑多个接收容器（30）上方的多个分配管道（50），以允许生物药物材料从多个分布 管道（50）通过重力进入多个接收容器（30）。多个接收容器（30）和歧管（20）相对于歧管外部的周围环境被密封，并且多个容器抑制生物药物的污染 当所述生物药物材料位于所述多个接收容器（30和所述歧管）中的至少一个中时，所述材料是所述材料。

公开(公告)号：WO2011163379A3

公开(公告)日：2012-04-19

申请号：PCT/US2011041471

申请日：2011-06-22

Applicant: BIOJECT INC ,  WILLIAMSON DANIEL E ,  MARSHALL JOHN R

Inventor： WILLIAMSON DANIEL E ,  MARSHALL JOHN R

IPC: B65B3/12 ,  A61J1/06 ,  A61J1/20 ,  A61J3/00 ,  B65B3/04

CPC classification number: A61M5/1782 ,  A61M5/24 ,  A61M5/30 ,  B65B3/003

Abstract: A filling device for a needle-free injector system is provided that is adapted to sterilely deliver a predetermined amount of an injectate from a vial to a plurality of cartridges. The filling device normally includes a single-use fluid path disposed between the vial and a receiving cartridge. The fluid path may include a vial connector adapted to couple to a vial, a filler head, and a conduit connecting the vial connector and filler head. The filling device typically further includes a pump coupled to the fluid path and adapted to propel the injectate from the vial to the receiving cartridge, and a cartridge-advancing element. Activation of the cartridge-advancing element is adapted to sequentially advance empty cartridges into a position opposite the filler head. Also provided are disposable fluid path kits and methods of using the filling device.

Abstract translation: 提供了一种用于无针注射器系统的填充装置，其适于将预定量的注射器从小瓶输送到多个药筒。 填充装置通常包括设置在小瓶和接收盒之间的一次性流体路径。 流体路径可以包括适于联接到小瓶，填充头和连接小瓶连接器和填充头的导管的小瓶连接器。 填充装置通常还包括耦合到流体路径并适于将注射器从小瓶推进到接收盒的泵和盒推进元件。 盒前进元件的激活适于将空墨盒顺序地提前到与填充头相对的位置。 还提供了一次性流体路径套件和使用填充装置的方法。

公开(公告)号：WO2011027874A1

公开(公告)日：2011-03-10

申请号：PCT/JP2010/065179

申请日：2010-09-03

Applicant: ソニーケミカル&インフォメーションデバイス株式会社 ,  新家 由久 ,  遠藤 靖実 ,  須山 行雄

Inventor： 新家　由久 ,  遠藤　靖実 ,  須山　行雄

IPC: B65B3/12 ,  G11B7/26

CPC classification number: B32B37/1284 ,  B29C65/1406 ,  B29C65/1435 ,  B29C65/1483 ,  B29C65/4845 ,  B29C65/524 ,  B29C65/7847 ,  B29C66/1122 ,  B29C66/244 ,  B29C66/324 ,  B29C66/342 ,  B29C66/45 ,  B29C66/452 ,  B29C66/73366 ,  B29C66/7465 ,  B29C66/8322 ,  B29L2031/3475 ,  B32B2457/202 ,  G02F1/1303 ,  G02F1/1339 ,  G02F2202/28 ,  Y10T156/1798

Abstract: 　大型の板状体の貼り合わせ工程にも適用でき、気泡の混入も防止しながら行う充填装置を提供する。　板状体（２，３）を、板状体（２，３）の主面を対向させて保持する複数の保持台（４，５）と、複数の保持台（４，５）を近接離間させる移動部材（６）と、板状体（２，３）の間に挿通され、充填液（７）を板状体（２，３）間に吐出する吐出ノズル（１０）と、吐出ノズル（１０）を、板状体（２，３）の面内方向に亘って移動させるノズル移動機構（１１）と、充填液（７）を貯蔵する貯蔵部（１５）と、貯蔵部（１５）に貯蔵されている充填液（７）を吐出ノズル（１０）から吐出させる押圧機構（１３）とを備え、吐出ノズル（１０）から吐出される充填液（７）を、相対向して支持された板状体（２，３）に接触させながら充填していく。

Abstract translation: 提供一种填充装置，其可以用于粘附大板构件的步骤，并且在防止气泡混合的同时进行填充。 一种装置设置有多个用于保持板构件（2,3）的保持台（4,5），使得板构件（2,3）的主表面彼此面对; 移动构件（6），其使所述多个保持台（4,5）彼此靠近或分开地移动; 排出喷嘴（10），其插入在所述板构件（2,3）之间并排出所述板构件（2,3）之间的填充流体（7）; 喷嘴移动机构（11），其在所述板构件（2,3）的表面方向上移动所述排出喷嘴（10）; 用于存储填充流体（7）的存储部分（15）; 以及用于使储存在储存部分（15）中的填充流体（7）从排放喷嘴（10）排出的功能的压力机构（13）。 其中从所述排出喷嘴（10）排出的所述填充流体（7）被填充，同时所述流体与被支撑以使得它们彼此面对的所述板构件（2,3）接触。

公开(公告)号：WO2010142016A1

公开(公告)日：2010-12-16

申请号：PCT/CA2010/000653

申请日：2010-05-04

Applicant: SURFACE TECHNOLOGIES IP AG ,  FICAI, Pietrandrea, G. ,  SOMERS, Pierre

Inventor： FICAI, Pietrandrea, G. ,  SOMERS, Pierre

IPC: B65B3/12 ,  B65B3/10 ,  B65B3/26 ,  B65B31/00 ,  B67D7/02 ,  B67D7/06 ,  B67D7/72

CPC classification number: B65D1/06 ,  B65B31/003

Abstract: A refilling apparatus for a refillable container and associated methodology is described and wherein the apparatus includes a refillable dispensing container; a source of pressurized propellant for delivery to the refillable dispensing container; a valve coupled in fluid flowing relation relative to the source of pressurized propellant; a source of a liquid to be dispensed by the refillable container and which is coupled in fluid flowing relation relative to the valve, and a pressurized vessel positioned downstream relative to both the sources of the liquid to be dispensed, and the pressurized propellant, as well as the valve, and which encloses a volume of the liquid to be dispensed to refill a depleted refillable dispensing container when the refillable dispensing container engages the valve.

Abstract translation: 描述了用于可再填充容器和相关联的方法的再填充装置，并且其中所述装置包括可再填充的分配容器; 用于输送到可再填充的分配容器的加压推进剂源; 相对于加压推进剂源流体流动关系的阀; 由可再填充容器分配的液体源，其相对于阀以流体流动的关系联接，以及位于相对于待分配液体的两个源的下游的加压容器以及加压推进剂，以及 作为阀，并且当可再填充分配容器接合阀时，其包围待分配的液体的体积以重新填充耗尽的可再填充分配容器。

公开(公告)号：WO2010102716A3

公开(公告)日：2010-12-09

申请号：PCT/EP2010001121

申请日：2010-02-24

Applicant: NESTEC SA ,  WALKER JOHN HOWARD ,  LEADBEATER JOHN MICHAEL ,  SUTTON JONATHAN

Inventor： WALKER JOHN HOWARD ,  LEADBEATER JOHN MICHAEL ,  SUTTON JONATHAN

IPC: B65B3/12 ,  A23G1/20 ,  A23G3/02 ,  A23G3/20 ,  B05C5/02 ,  F16K1/08 ,  G01F11/32 ,  G01F15/00

CPC classification number: F16K1/08 ,  A21C5/006 ,  A21C9/08 ,  A21C11/16 ,  A23G1/0066 ,  A23G1/205 ,  A23G1/206 ,  A23G3/0027 ,  A23G3/0236 ,  A23G3/0252 ,  A23G3/0257 ,  A23G3/20 ,  A23G3/2023 ,  A23G3/203 ,  B05C5/0225 ,  F16K1/04

Abstract: An apparatus for depositing a liquid, semi-liquid or semi-solid food product. The apparatus comprises a fixed volume chamber for receiving the food product under a positive pressure, the chamber being defined by chamber walls, one of the chamber walls being provided with an outlet orifice for depositing the food product, the outlet orifice being provided with a first sealing surface. The apparatus also comprises a valve spindle arranged for reciprocating movement within the chamber, the length direction of the valve spindle extending substantially perpendicular to the chamber wall in which the outlet orifice is provided, a first end of the valve spindle being provided with a second sealing surface. The second sealing surface of the valve spindle is arranged for abutting the first sealing surface of the outlet orifice to thereby close the outlet orifice.

Abstract translation: 一种用于沉积液体，半液体或半固体食品的设备。 该装置包括用于在正压力下接收食品的固定容积室，该室由室壁限定，其中一个室壁设置有用于沉积食品的出口孔，出口孔设置有第一 密封面。 该装置还包括一个阀芯，其布置用于在室内往复运动，该阀芯的长度方向基本上垂直于设置有出口孔的室壁延伸，该阀芯的第一端设有第二密封件 表面。 阀芯的第二密封面被布置成邻接出口孔的第一密封表面，从而封闭出口孔。

公开(公告)号：WO2009063253A2

公开(公告)日：2009-05-22

申请号：PCT/GB2008/051076

申请日：2008-11-17

Applicant: U-POL LIMITED ,  JULIEN, Jean-Charles

Inventor： JULIEN, Jean-Charles

IPC: B65B31/02 ,  B65B3/12

CPC classification number: B65B31/00 ,  B65D83/42

Abstract: An aerosol can filling machine has a piston (15,16) and dosage cup (4) for dispensing a dosage of flowable material into an aerosol can (8). The hopper (3) comprises a reservoir for storing the flowable material and a reservoir aperture through which said piston is moveable. A connector (2) is provided for connecting the reservoir to the dosage cup (4) and feeding flowable material thereto. The connecter (2) locating the reservoir between piston (15,16) and dosage cup (4) such that, in use, the piston (15,16) is moveable through the reservoir and into the dosage cup (4) for injecting a quantity of flowable material into the aerosol can (8). The aerosol can filling machine also having locator control means for preventing repeated operation until a locator switch (20) detects that the aerosol can (8) has been removed and replaced.

Abstract translation: 气溶胶罐灌装机具有用于将一定量的可流动材料分配到气溶胶罐（8）中的活塞（15,16）和剂量杯（4）。 料斗（3）包括用于存储可流动材料的储存器和储存器孔，所述活塞可通过该储存器孔运动。 提供一个连接器（2），用于将储存器连接到剂量杯（4）上并将可流动材料供给到其上。 连接器（2）将储存器定位在活塞（15,16）和剂量杯（4）之间，使得在使用中，活塞（15,16）能够通过储存器移动到剂量杯（4）中，用于注入 可流动材料的数量进入气溶胶罐（8）。 气溶胶罐灌装机还具有用于防止重复操作的定位器控制装置，直到定位开关（20）检测到气溶胶罐（8）已被移除和更换为止。

公开(公告)号：WO2008084234A3

公开(公告)日：2008-12-04

申请号：PCT/GB2008000079

申请日：2008-01-09

Applicant: IMI VISION LTD ,  NIGHY RICHARD JOHN

Inventor： NIGHY RICHARD JOHN

IPC: B65B3/12 ,  B67D7/02

CPC classification number: B67D1/0037 ,  B65B3/045 ,  B65D75/5872 ,  B67D1/0022 ,  B67D1/0031 ,  B67D1/0044 ,  B67D1/0048 ,  B67D1/0079 ,  B67D1/0888 ,  B67D1/1231 ,  B67D1/1234 ,  B67D1/1243 ,  B67D2001/082

Abstract: An apparatus for introducing a selected beverage into a flexible pouch (8), sealingly closing the pouch (8) and dispensing the closed pouch (8). The apparatus comprises a housing (4) adapted to, in use, accept a plurality of reservoirs (10) of beverage concentrate. Each reservoir (10) has a concentrate pump (12) provided with a diluent inlet and a mixer for mixing pumped concentrate with diluent to produce a mixed beverage. Leading from each pump (12) is flexible conduit (14) terminating in a nozzle (68) for dispensing the mixed beverage. The apparatus further comprises a multiple dispense head (20) for accepting the plurality of nozzles (68), the nozzles (68) being movable relative to a filling position such that any one of the nozzles (68) can be presented at the filling position, a means for, in use, selecting a flexible pouch (8) and bringing it into alignment with a nozzle (68) in the filling position where it is filled via an opening therein, and a means for, in use, sealingly closing the opening and dispensing the filled sealed flexible pouch (8) from the apparatus. Methods of loading a concentrate reservoir (10), disengaging a removable pump (12) and changing a removable pump (12) are also disclosed. A flexible pouch with rigid spout and mixing element are also disclosed.

Abstract translation: 一种用于将选择的饮料引入柔性袋（8）中的装置，密封地封闭袋（8）并分配封闭的袋（8）。 该装置包括适于在使用中接纳饮料浓缩物的多个储存器（10）的壳体（4）。 每个储存器（10）具有设置有稀释剂入口的浓缩物泵（12）和用于将泵送的浓缩物与稀释剂混合以产生混合饮料的混合器。 从每个泵（12）引出的是柔性导管（14），其终止于用于分配混合饮料的喷嘴（68）中。 该装置还包括用于接收多个喷嘴（68）的多个分注头（20），喷嘴（68）可相对于填充位置移动，使得任何一个喷嘴（68）可以呈现在填充位置 ，用于在使用中选择柔性袋（8）并使其与其中通过其中的开口填充的填充位置中的喷嘴（68）对准的装置，以及用于在使用中密封地关闭 从装置中打开和分配填充的密封柔性袋（8）。 还公开了装载浓缩物储存器（10），分离可移除泵（12）和改变可移除泵（12）的方法。 还公开了具有刚性喷口和混合元件的柔性袋。