THERAPEUTIC COMPOUNDS ISOLATED FORM CALOMERIA AMARNTHOIDES
    33.
    发明申请
    THERAPEUTIC COMPOUNDS ISOLATED FORM CALOMERIA AMARNTHOIDES 审中-公开
    治疗化合物分离型卡马西亚钠

    公开(公告)号:WO2006067603A1

    公开(公告)日:2006-06-29

    申请号:PCT/IB2005/003874

    申请日:2005-12-23

    CPC classification number: A61K31/343

    Abstract: The present invention relates to extracts and compounds which are isolated from Calomeria amaranthoides, and to derivatives and analogues of such compounds, which demonstrate cytotoxic activity against a variety of cell types exhibiting hyperproliferative cell division.

    Abstract translation: 本发明涉及从Cal ho are分离的提取物和化合物,以及这些化合物的衍生物和类似物,其显示出对多种增殖细胞分裂的多种细胞类型的细胞毒活性。

    TORPEDO PILE WITH ENHANCED CLAMPING STRENGTH FOR ANCHORING FLOATING STRUCTURES AND METHOD OF INSTALLATION
    34.
    发明申请
    TORPEDO PILE WITH ENHANCED CLAMPING STRENGTH FOR ANCHORING FLOATING STRUCTURES AND METHOD OF INSTALLATION 审中-公开
    用于锚固浮动结构的增强夹紧强度的TORPEDO桩和安装方法

    公开(公告)号:WO2006067410A1

    公开(公告)日:2006-06-29

    申请号:PCT/GB2005/004931

    申请日:2005-12-20

    CPC classification number: B63B21/50 B63B21/29

    Abstract: A Torpedo Pile (100) is described for the anchoring of floating structures used for drilling and production wells for oil and gas, the pile (100) comprising a tapering body (1) provided with fins (20) and a point (30) for embedding in the seabed, its upper end being provided with at least two plates (2) provided with flaps (3), said flaps being capable of inducing a rotation of the articulation elements (4) when a dragging force is exerted on the system. With the continuation of the dragging force, the plates (2) continue to rotate as far as a final configuration, when the points of contact (6) of stops (5) are reached. The pile (100) comprises one embodiment for permanent anchorage and another for temporary anchorage. The method of installation/withdrawal of the two embodiments is also described.

    Abstract translation: 描述了用于锚定用于油气钻井和生产井的浮动结构的鱼雷桩(100),桩(100)包括具有翅片(20)的锥形体(1)和用于 包埋在海床中,其上端设置有至少两个设置有襟翼(3)的板(2),当所述系统上施加拖曳力时,所述襟翼能够引起关节元件(4)的旋转。 随着拖曳力的延续,当达到止挡件(5)的接触点(6)时,板(2)继续旋转直到最终构造。 桩(100)包括用于永久锚固的一个实施例,另一个用于临时锚固。 还描述了两个实施例的安装/取出方法。

    ALZHEIMER'S AND MILD COGNITIVE IMPAIRMENT DIAGNOSTICS
    35.
    发明申请
    ALZHEIMER'S AND MILD COGNITIVE IMPAIRMENT DIAGNOSTICS 审中-公开
    ALZHEIMER和MILD认知障碍诊断

    公开(公告)号:WO2006034542A1

    公开(公告)日:2006-04-06

    申请号:PCT/AU2005/001485

    申请日:2005-09-27

    Inventor: KHALIL, Zeinab

    CPC classification number: A61K49/0006

    Abstract: A method of Alzheimer's disease diagnosis and/or diagnosis of MCI in a patient comprising: (i) dermally administering to the patient an amount of an endothelial acting vasodilating agent effective to induce local microvascular dilation in a normal patient; and (ii) detecting local microvascular blood flow change following vasodilating agent administration; wherein Alzheimer's disease and/or MCI is indicated if vasodilating agent induced microvascular dilation is reduced in a statistically significant manner relative to dilation detected in a normal patient population. The invention also relates to a diagnostic kit for detecting Alzheimer's disease and/or MCI.

    Abstract translation: 一种阿尔茨海默病在患者中诊断和/或诊断MCI的方法,包括:(i)向患者皮肤施用一定量的有效诱导正常患者局部微血管扩张的内皮作用血管舒张剂; 和(ii)在血管舒张剂给药后检测局部微血管血流变化; 如果血管扩张剂诱导的微血管扩张相对于在正常患者群体中检测到的扩张以统计学显着的方式降低,则表明阿尔茨海默病和/或MCI。 本发明还涉及用于检测阿尔茨海默病和/或MCI的诊断试剂盒。

    FLUID LEVEL SENSING APPARATUS AND METHOD FOR A SPRAY APPLICATOR
    36.
    发明申请
    FLUID LEVEL SENSING APPARATUS AND METHOD FOR A SPRAY APPLICATOR 审中-公开
    液体水平传感装置和喷雾装置的方法

    公开(公告)号:WO2005060539A2

    公开(公告)日:2005-07-07

    申请号:PCT/US2004/040064

    申请日:2004-11-30

    Abstract: The present invention relates to a level sensing spray applicator. In one embodiment, the spray applicator includes a gun that receives a liquid and a supply vessel coupled to the gun. The vessel includes a level sensor responsive to the volume retained by the supply vessel. In another aspect, a level-sensing supply vessel includes a level sensor responsive to a volume of liquid retained by the supply vessel, the sensor including a sensor element to detect the volume by sensing a resistance property of the liquid. In still a further aspect, a method of sensing a level of a liquid retained within a storage vessel includes sensing a first liquid volume, removing a portion of the first volume to define a second volume, determining if the second volume is less than a minimum volume, and generating an alarm signal if the second volume is less than the minimum volume.

    Abstract translation: 本发明涉及液位传感喷雾器。 在一个实施例中,喷涂器包括接收液体的枪和连接到枪的供应容器。 容器包括响应于由供给容器保留的体积的液位传感器。 在另一方面,液位感测供应容器包括响应于由供应容器保留的液体体积的液位传感器,该传感器包括通过感测液体的电阻特性来检测体积的传感器元件。 在另一方面,一种感测保存在存储容器内的液体水平的方法包括检测第一液体体积,去除第一体积的一部分以限定第二体积,确定第二体积是否小于最小值 并且如果第二卷小于最小音量则产生报警信号。

    MAGNETIC ROD APPARATUS AND METHOD FOR MANIPULATING MAGNETIC PARTICLES FOR DETECTING ANALYTES
    37.
    发明申请
    MAGNETIC ROD APPARATUS AND METHOD FOR MANIPULATING MAGNETIC PARTICLES FOR DETECTING ANALYTES 审中-公开
    用于检测分析物的磁性粒子操作磁棒装置和方法

    公开(公告)号:WO2005059929A2

    公开(公告)日:2005-06-30

    申请号:PCT/US2004/042022

    申请日:2004-12-13

    IPC: H01F

    CPC classification number: H01F7/20 B82Y25/00 G01N35/0098 H01F1/0045

    Abstract: Disclosed herein are electromagnetic rod devices, systems and methods using the same, for manipulating magnetic particles within a fluid sample well to facilitate processing the magnetic particles for detection of analytes bound thereto. The electromagnetic rods are used to transfer magnetic particles between different sample wells in a multi-step analyte detection procedure and /or to facilitate washing of the magnetic particles within a sample well. The electromagnetic rod devices include an upper portion, and a lower portion configured as a tip or configured to engage a disposable tip sheath. Magnetic particles are alternatively engaged and disengaged with the surface of the tip or the tip sheath by turning the electromagnet on and off at selected times. The electromagnetic rod devices may optionally be configured with an actuator assembly to move the electromagnetic rod devices vertically and/or horizontally in an instrument system configured for performing biological assays.

    Abstract translation: 本文公开了电磁棒装置,使用该装置的系统和方法,用于操纵流体样品池内的磁性颗粒以促进处理该磁性颗粒以检测与其结合的分析物。 电磁棒用于在多步分析物检测程序中在不同样品孔之间转移磁性颗粒和/或便于清洗样品孔内的磁性颗粒。 电磁杆装置包括上部和下部,下部构造成尖端或者构造成接合一次性尖端护套。 通过在选定时间打开和关闭电磁体,磁性颗粒交替地与尖端或尖端护套的表面接合和脱离。 电磁杆装置可以可选地配置有致动器组件以在被配置用于执行生物测定的仪器系统中垂直和/或水平地移动电磁杆装置。

    PRODUCTION OF PLANT SECONDARY METABOLITES USING ADSORPTION AND ELICITATION IN CELL SUSPENSION CULTURE
    38.
    发明申请
    PRODUCTION OF PLANT SECONDARY METABOLITES USING ADSORPTION AND ELICITATION IN CELL SUSPENSION CULTURE 审中-公开
    在细胞悬浮培养中使用吸附和释放的植物次生代谢产物的生产

    公开(公告)号:WO2005012507A1

    公开(公告)日:2005-02-10

    申请号:PCT/AU2004/000991

    申请日:2004-07-23

    CPC classification number: C12N5/0025 A01H4/001 C12N5/04 C12P7/22

    Abstract: The invention discloses a method of producing a plant secondary metabolite of interest,comprising: (a) cultivating by suspension culture in a suitable nutrient medium plant cells that produce the secondary metabolite; (b) including within the suspension culture an amount of adsorbent and one or more elicitor agents suitable to increase production of the secondary metabolite; (c)recovering the secondary metabolite from the suspension culture. In a preferred emobidment the invention discloses a method of producing a stilbene plant secondary metabolite of interest, comprising: (a) cultivating by suspension culture in a suitable nutrient medium plant cells that produce a stilbene secondary metabolite; (b) including within the suspension culture an amount of adsorbent and one or more elicitor agents suitable to increase production of the stilbene; (c) recovering the stilbene from the suspension culture.

    Abstract translation: 本发明公开了一种生产感兴趣的植物次生代谢物的方法,包括:(a)通过悬浮培养培养在合适的营养培养基中产生次级代谢物的植物细胞; (b)在悬浮培养物中包含一定量的吸附剂和一种或多种适于增加次级代谢产物产生的诱导剂; (c)从悬浮培养物中回收次级代谢物。 在优选的方案中,本发明公开了一种生产茋植物次要代谢产物的方法,其包括:(a)通过悬浮培养在合适的营养培养基中培养产生二苯乙烯次级代谢物的植物细胞; (b)在悬浮培养物中包含一定量的吸附剂和一种或多种适于增加芪生产的诱导剂; (c)从悬浮培养物中回收二苯乙烯。

    METHOD FOR, AND THE CONSTRUCTION OF, A LONG-DISTANCE WELL FOR THE PRODUCTION, TRANSPORT, STORAGE AND EXPLOITATION OF MINERAL LAYERS AND FLUIDS
    39.
    发明申请
    METHOD FOR, AND THE CONSTRUCTION OF, A LONG-DISTANCE WELL FOR THE PRODUCTION, TRANSPORT, STORAGE AND EXPLOITATION OF MINERAL LAYERS AND FLUIDS 审中-公开
    用于生产,运输,储存和利用矿物层和流体的长距离井的方法和建造

    公开(公告)号:WO2005003509A1

    公开(公告)日:2005-01-13

    申请号:PCT/GB2003/002809

    申请日:2003-06-30

    CPC classification number: E21B43/017 E21B43/305

    Abstract: A method is described for the construction of an arrangement of Extended Reach Wells (ERW) for the production, transport, and exploitation of mineral layers, in that an offshore reservoir of fluids (3) is initially penetrated by an initial well (1), followed by penetration by a multilateral well (2), close to or connected at the end of the drilling section (5) of the multilateral well (2) to the end of the drilling section (7) of the initial well (1). A well of long distance is therefore formed, connected hydraulically at one end (6) of the multilateral well (2) to end (7) of the initial well and to the production unit (8). The resulting long-distance well allows for the drainage of the reservoir in deep and extremely deep water (10) from a platform in shallower water (9).

    Abstract translation: 描述了一种用于构建用于矿物层的生产,运输和开采的延伸井(ERW)的布置的方法,其中最初由初始井(1)渗透流体(3)的近海储层, 随后在多孔井(2)的钻井段(5)的最后端接近或连接到初井(1)的钻井段(7)的末端的多边井(2)穿透。 因此,形成长距离井,在多孔井(2)的一端(6)至初始井的端部(7)和生产单元(8)之间液压连接。 所产生的长距离井允许在较浅的水(9)中的平台在深水和极深的水(10)中排放储存器。

    COMPLEXING RESINS AND METHOD FOR PREPARATION THEREOF
    40.
    发明申请
    COMPLEXING RESINS AND METHOD FOR PREPARATION THEREOF 审中-公开
    复合树脂及其制备方法

    公开(公告)号:WO2003057739A1

    公开(公告)日:2003-07-17

    申请号:PCT/AU2003/000015

    申请日:2003-01-08

    CPC classification number: C08K3/22 C08F2/08 C08F2/44 C08F8/32 C08F220/32

    Abstract: The invention provides a process for preparing polymeric beads of complexing resin incorporating magnetic particles, which process comprises: producing a dispersion having a continuous aqueous phase and a dispersed organic phase, said organic phase comprising one or more polymerisable monomers, magnetic particles and a dispersing agent for dispersing said magnetic particles in the organic phase; polymerising said one or more polymerisable monomers to form polymeric beads incorporating said magnetic particles, wherein said polymeric beads include amine groups capable of complexing a transition metal cation, or wherein said polymeric beads are reacted with one or more compounds to provide amine groups capable of complexing a transition metal cation, complexing resins prepared by this process, and polymeric beads of complexing resin comprising a polymer matrix having magnetic particles dispersed substantially uniformly therein, wherein the polymer matrix incorporates amine groups capable of complexing a transition metal cation.

    Abstract translation: 本发明提供了一种制备掺入磁性颗粒的络合树脂的聚合物珠的方法,该方法包括:制备具有连续水相和分散有机相的分散体,所述有机相包含一种或多种可聚合单体,磁性颗粒和分散剂 用于将所述磁性颗粒分散在有机相中; 聚合所述一种或多种可聚合单体以形成掺入所述磁性颗粒的聚合物珠,其中所述聚合物珠粒包括能够络合过渡金属阳离子的胺基团,或其中所述聚合物珠粒与一种或多种化合物反应以提供能够络合的胺基团 过渡金属阳离子,通过该方法制备的络合树脂和包含具有基本均匀分散的磁性颗粒的聚合物基质的络合树脂的聚合物珠粒,其中聚合物基质包含能够络合过渡金属阳离子的胺基团。

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