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    METHOD AND APPARATUS FOR GENDER SELECTION BASED ON PH
    42.
    发明申请
    METHOD AND APPARATUS FOR GENDER SELECTION BASED ON PH 审中-公开
    基于PH的性别选择方法与设备

    公开(公告)号：WO2008088601A2

    公开(公告)日：2008-07-24

    申请号：PCT/US2007/083235

    申请日：2007-10-31

    Applicant: TEXAS TECH UNIVERSITY SYSTEM ,  PRIEN, Samuel, D. ,  PENROSE, Lindsay, L.

    Inventor： PRIEN, Samuel, D. ,  PENROSE, Lindsay, L.

    IPC: C12N5/06

    CPC classification number: C12M47/04 ,  C12N5/0612

    Abstract: The present invention includes methods and apparatus to separate X or Y-chromosome bearing sperm cells in a population by first placing the population of sperm cells at physiological pH environment, and simultaneously contacting the population of sperm cells with one or more additional sub-environments with different pH values. The exposure allows mobile sperm cells bearing X or Y-chromosome to migrate to the different pH sub-environments, wherein each cell only exposed or come in contact with one pH sub-environment. Finally, the collecting X or Y- chromosome enriched population of sperm cells is performed.

    Abstract translation: 本发明包括通过首先将精子细胞群体置于生理pH环境中来分离群体中携带X或Y染色体的精子细胞的方法和装置，同时使精子细胞群与一个或多个其它亚环境接触， 不同的pH值。 暴露允许携带X或Y染色体的移动精子细胞迁移到不同的pH亚环境，其中每个细胞仅暴露或与一个pH亚环境接触。 最后，进行收集X或Y染色体富集的精子细胞群体。

    METHOD FOR RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM ACTIVATION AND CONTROL THEREOF
    43.
    发明申请
    METHOD FOR RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM ACTIVATION AND CONTROL THEREOF 审中-公开
    用于肾素 - 血管紧张素 - 阿尔托斯酮系统激活和控制的方法

    公开(公告)号：WO2006135621A2

    公开(公告)日：2006-12-21

    申请号：PCT/US2006/022028

    申请日：2006-06-07

    Applicant: TEXAS TECH UNIVERSITY ,  SIMONI, Jan S. ,  SIMONI, Grace ,  MOELLER, John F.

    Inventor： SIMONI, Jan S. ,  SIMONI, Grace ,  MOELLER, John F.

    IPC: A61K31/00 ,  A61K35/14 ,  A61K45/06 ,  A61P7/08

    CPC classification number: A61K45/06 ,  A61K31/401 ,  A61K31/41 ,  A61K31/4184 ,  A61K31/585 ,  A61K35/14 ,  A61K38/42 ,  A61K38/556 ,  A61K2300/00

    Abstract: An improved blood substitute composition comprising a blood substitute and a renin-angiotensin-aldosterone An improved blood substitute composition comprising a blood substitute and a renin-angiotensin-aldosterone system inhibitor. A method of treating a patient having a disorder requiring a blood transfusion comprising administering a free hemoglobin based blood substitute and a renin-angiotensin-aldosterone system inhibitor. A renin-angiotensin-aldosterone system activator comprising hemoglobin or hemoglobin and a peroxide. A method of increasing the activity of angiotensin converting enzyme comprising incubation with hemoglobin or hemoglobin and peroxide. A method according of activating the renin-angiotensin-aldosterone system comprising contacting in vivo a free hemoglobin based blood substitute with a peroxide wherein the product induces the production of angiotensin I metabolites which comprise metabolites capable of affecting the vascular tone and/or stimulating aldosterone production.

    Abstract translation: 包含血液替代物和肾素 - 血管紧张素 - 醛固酮的改进的血液替代物组合物包含血液代用品和肾素 - 血管紧张素 - 醛固酮系统抑制剂的改进的血液替代物组合物。 一种治疗患有需要输血的病症的方法，包括施用游离血红蛋白基血液替代物和肾素 - 血管紧张素 - 醛固酮系统抑制剂。 包含血红蛋白或血红蛋白和过氧化物的肾素 - 血管紧张素 - 醛固酮系统激活剂。 包括增加血管紧张素转换酶的活性的方法，包括与血红蛋白或血红蛋白和过氧化物孵育。 一种激活肾素 - 血管紧张素 - 醛固酮系统的方法，其包括使体内游离血红蛋白基血液替代物与过氧化物接触，其中所述产物诱导产生能够影响血管紧张度和/或刺激醛固酮生成的代谢物的血管紧张素I代谢物 。

    CASTOR OIL/EPOXIDIZED SOYBEAN OIL BASED ELASTOMERIC COMPOSITIONS
    45.
    发明申请
    CASTOR OIL/EPOXIDIZED SOYBEAN OIL BASED ELASTOMERIC COMPOSITIONS 审中-公开
    蓖麻油/环氧化大豆油基弹性体组合物

    公开(公告)号：WO2004063245A1

    公开(公告)日：2004-07-29

    申请号：PCT/US2004/000475

    申请日：2004-01-08

    Applicant: TEXAS TECH UNIVERSITY ,  PARKER, Harry, W. ,  TOCK, Richard, W. ,  QIAO, Fang ,  LENOX, Ronald, S.

    Inventor： PARKER, Harry, W. ,  TOCK, Richard, W. ,  QIAO, Fang ,  LENOX, Ronald, S.

    IPC: C08G59/00

    CPC classification number: C08G59/186 ,  C08G59/4284 ,  C08K3/013 ,  C08K5/0025 ,  C08L63/00 ,  C08L67/00 ,  C08L2666/22

    Abstract: Elastomers are formed from castor oil and/or ricinoleic acid estolides and a polyester formed form an epoxidized vegetable oil such as ESO and a polycarboxylic acid such as sebacic acid, optionally in the presence of a peroxide initiator, or include crosslinked reaction products derived from ricinoleic acid or castor oil estolides, epoxy group-containing compounds such as epoxy resins and/or epoxidized vegetable oil, epoxy hardeners such as polyamine and polycarboxylic acid hardeners, thermally activated free radical initiators such as peroxides, and optionally but preferably include fillers such as limestone or wood flour. The elastomers can be prepared using a two-step, solvent-less procedure at elevated or ambient temperatures. These predominantly “all-natural” elastomers have physical properties comparable to conventional petroleum-based elastomers and composites and exhibit good flexibility, resiliency, abrasion resistance and inertness to hydrolysis. The resulting elastomers display good mechanical strength and resiliency, are resistant to abrasion and hydrolysis, and can be processed into sheet materials, which makes them attractive a floor covering components.

    Abstract translation: 弹性体由蓖麻油和/或蓖麻油酸酯和由环氧化植物油如ESO和多元羧酸如癸二酸形成的聚酯，任选在过氧化物引发剂的存在下形成，或包括衍生自蓖麻油酸的交联反应产物 酸或蓖麻油，含环氧基的化合物如环氧树脂和/或环氧化植物油，环氧硬化剂如多胺和多元羧酸硬化剂，热活化的自由基引发剂如过氧化物，以及任选但优选包括填料如石灰石 或木粉。 弹性体可以在升高或环境温度下使用两步无溶剂方法制备。 这些主要的“全天然”弹性体具有与传统的基于石油的弹性体和复合材料相当的物理性能，并且具有良好的柔韧性，弹性，耐磨性和对水解的惰性。 所得到的弹性体显示良好的机械强度和弹性，耐磨损和水解，并且可以加工成片材，这使得它们具有吸引力的地板覆盖部件。

    MAMMALIAN MIGRATION INDUCTING GENE AND METHODS FOR DETECTION AND INHIBITION OF MIGRATING TUMOR CELLS
    46.
    发明申请
    MAMMALIAN MIGRATION INDUCTING GENE AND METHODS FOR DETECTION AND INHIBITION OF MIGRATING TUMOR CELLS 审中-公开

    公开(公告)号：WO2003066808A3

    公开(公告)日：2003-08-14

    申请号：PCT/US2003/002047

    申请日：2003-01-23

    Applicant: TEXAS TECH UNIVERSITY ,  LINDSEY, Suzanne, J.

    Inventor： LINDSEY, Suzanne, J.

    IPC: C07H21/04

    Abstract: The present invention relates to isolated nucleic acid molecules conferring on mammalian carcinoma cells an ability to undergo cell migration. Recombinant DNA expression systems and host cells containing the subject nucleic acid molecule, as well as antisense oligonucleotides, are also described. Also disclosed are methods of inhibiting expresssion of the subject nucleic acid molecule, inhibiting production of the encoded protein or polypeptide, inhibiting metastasis of a carcinoma cell in a subject (including in humans), inhibiting migration of carcinoma cell in a subject, detecting the presence of a migrating carcinoma cell in a sample of a subject's tissue or body fluids, and inhibiting the migration of a placental cell into the blood stream of a female mammal.

    MAMMALIAN MIGRATION INDUCTING GENE AND METHODS FOR DETECTION AND INHIBITION OF MIGRATING TUMOR CELLS
    47.
    发明申请
    MAMMALIAN MIGRATION INDUCTING GENE AND METHODS FOR DETECTION AND INHIBITION OF MIGRATING TUMOR CELLS 审中-公开
    MAMMALIAN移植诱导基因和检测和抑制移植肿瘤细胞的方法

    公开(公告)号：WO2003066808A2

    公开(公告)日：2003-08-14

    申请号：PCT/US2003/002047

    申请日：2003-01-23

    Applicant: TEXAS TECH UNIVERSITY ,  LINDSEY, Suzanne, J.

    Inventor： LINDSEY, Suzanne, J.

    IPC: C12N

    CPC classification number: C07K14/4702 ,  A61K48/00 ,  C07K14/47 ,  C12Q1/6886 ,  C12Q2600/158 ,  G01N33/57484

    Abstract: The present invention relates to isolated nucleic acid molecules conferring on mammalian carcinoma cells an ability to undergo cell migration. Recombinant DNA expression systems and host cells containing the subject nucleic acid molecule, as well as antisense oligonucleotides, are also described. Also disclosed are methods of inhibiting expresssion of the subject nucleic acid molecule, inhibiting production of the encoded protein or polypeptide, inhibiting metastasis of a carcinoma cell in a subject (including in humans), inhibiting migration of carcinoma cell in a subject, detecting the presence of a migrating carcinoma cell in a sample of a subject's tissue or body fluids, and inhibiting the migration of a placental cell into the blood stream of a female mammal.

    Abstract translation: 本发明涉及赋予哺乳动物癌细胞细胞迁移能力的分离的核酸分子。 还描述了重组DNA表达系统和含有目标核酸分子的宿主细胞以及反义寡核苷酸。 还公开了抑制受试者核酸分子表达的方法，抑制编码的蛋白质或多肽的产生，抑制受试者（包括在人体中）的癌细胞的转移，抑制受试者中癌细胞的迁移， 的受试者组织或体液样品中的迁移性癌细胞，并抑制胎盘细胞迁移到雌性哺乳动物的血液中。

    PREPARATION OF CHITIN NANOCRYSTALS AND NANOWHISKERS FROM CRUSTACEAN BIOMASS USING IONIC LIQUID
    50.
    发明申请
    PREPARATION OF CHITIN NANOCRYSTALS AND NANOWHISKERS FROM CRUSTACEAN BIOMASS USING IONIC LIQUID 审中-公开

    公开(公告)号：WO2023059499A1

    公开(公告)日：2023-04-13

    申请号：PCT/US2022/045177

    申请日：2022-09-29

    Applicant: TEXAS TECH UNIVERSITY SYSTEM

    Inventor： SHAMSHINA, Julia, L. ,  ABIDI, Noureddine

    IPC: C08B37/08

    Abstract: The present invention includes a method for the preparation of chitin nanocrystals, nanowhiskers, or both directly from a raw chitinous biomass without the prior isolation of a raw chitin polymer using an ionic liquid comprising: drying the raw chitinous biomass; and extracting in a single step a purified chitin by hydrolyzing with an ionic liquid from a raw, unpurified chitinous biomass, wherein the chitin nanocrystals and nanowhiskers comprise at least one of a high aspect ratio, are highly crystalline, or have high thermal stability.

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