Abstract:
Devices for occluding an aperture in tissue or a vessel comprise a first flexible wire and a second flexible wire. Each of the first and second wires is comprised of a shape memory material. Each of the first and second wires is shaped into first and second geometric forms such that the first geometric form of the first wire and the first geometric form of the second wire form a first plate in a first plane, and the second geometric form of the first wire and the second geometric form of the second wire form a second plate in a second plane that is parallel to and remote from the first plane. The first and second plates are separated by a waist formed from two portions of the first wire and two portions of the second wire. Methods for occluding an aperture in tissue or a vessel using such devices are also provided.
Abstract:
An occlusion device for closing an anatomical defect in tissue comprising a conduit connecting an opening on a first tissue and an opening on a second tissue is provided. The occlusion device comprises a scaffold comprising a) a proximal support structure comprising at least two arms; b) a distal support structure comprising at least two arms, wherein the arms are adapted to provide anchorage for the device in the tissue; and c) a waist portion adapted for extending through the opening on the first tissue and connecting the proximal support structure with the distal support structure, wherein the scaffold consists essentially of a biodegradable polymer, wherein the proximal support structure and the distal support structure comprise or consist of polycaprolactone (PCL), poly-(D,L-lactide-co-caprolactone) (PLC), or a mixture thereof. A method of closing an anatomical defect using the occlusion device is also provided.
Abstract:
Devices, tools, systems, kits and methods for closing a tissue opening non-invasively are presented. The devices include a tissue closure device that reliably induces eversion of tissue edges that define a tissue opening. The devices may be used in combination with an applicator tool to provide easy and uniform apposition of the tissue closure devices across the tissue opening. Further embodiments provide for releasable locking of the tissue closure devices, allowing for drainage of wound edema and/or treatment of infection, without removal and reapplication of the devices. Still further embodiments allow for the passing of moisture or other substances that may collect under a tissue closure device.
Abstract:
A stapling and cutting system for use by a physician in the cutting and stapling together of layers of body tissue. The system includes first and second handles that are pivotally coupled together at a pivot joint located between proximate and distal ends of each of handles. First and second jaws are coupled together and movable between an open and closed position. Mounted on a distal end of the first jaw for positioning on one side of the layers of tissue is a disposable staple cartridge, which includes a plurality of staples. An anvil, mounted on the distal end of the second jaw, is positioned on opposing side of the tissue to be stapled. To manipulate the jaws, a closure mechanism couples the first and second handles to the first and second jaws. The closure mechanism maintains the anvil and the staple cartridge substantially parallel to and opposite from one another when the first and second jaws are in the open position and moved to the closed position. When operated, the staples are discharged from the system and clinched when the first and second jaws are moved into the closed position.
Abstract:
Wound closure apparatus (30) is provided including a body (32) having an elongated, lowermost force-transmitting surface (72) operable to be placed in a proximal, external, wound-closing position on a patient, together with a force-exerting assembly (34) coupled with the body (32) and operable to exert a downwardly directed force serving to generate wound-closing pressure against the patient's tissue. The force-transmitting surface (72) is preferably three-dimensionally asymmetric so that forces of different magnitude are exerted at different locations along the length of the surface (72). The apparatus (30) is especially designed for the closure of wounds attendant to endovascular interventions, e.g., a femoral artery puncture wound (138) incident to percutaneous cardiac intervention (PCI), wherein the wound (138) has an insertion site (142), an oblique tract (144) within the patient's tissue (140), and an arteriotomy (146). In such uses, the apparatus (30) is positioned and operated so as to partially close the patient's artery (148) upstream of the arteriotomy (146), thereby lessening the patient's blood flow at the arteriotomy (146). The apparatus (30) is capable of quickly effecting wound closure with a time-to-ambulation (TTA) of approximately 60 minutes, and a very low complication rate. The apparatus and methods hereof may also be used for the closure of wounds created during venous intervention procedures.
Abstract:
A closure device having evertable arms for capturing and everting tissue and method for its use with an invasive scope, such as an endoscope, for full-thickness closure of perforations and leaks in the walls of an intraluminal bodily space.
Abstract:
An anastomosis normally closed clip comprising a first side including at least one first suture guide, the first suture guide being disposed on a top of the clip, the first end portion and the first suture guide defining a first suture space open toward the top of the clip, the first side further including a first carrier slot on the bottom of the clip; and a second side which is the mirror image of the first side. An introducer device is used to open the clip and introduce it into a patient over two organ segments to be sutured together and allow the clip to close. The suture spaces allow for continuous suturing of the organ segments. The introducer device is used to remove the clip from the patient after the suture procedure.
Abstract:
An apparatus for performing a vascular treatment includes an intraluminal member that is controUingly moved during the vascular treatment. The intraluminal member of the vascular treatment device can be connected to a motor. The intraluminal member may be configured to retain endothelium during the vascular treatment procedure.
Abstract:
A removable self-retaining suture system and methods for use thereof in emergency situations. The system comprises one or more self-retaining suture segments and a grasp engagement element. The system may be used for temporary wound closure in a trauma victim, and may be easily removed upon the availability of proper medical care to the victim.
Abstract:
A closure device having evertable arms for capturing and everting tissue and method for its use with an invasive scope, such as an endoscope, for full-thickness closure of perforations and leaks in the walls of an intraluminal bodily space.